• 제목/요약/키워드: Skin neoplasms/pathology

검색결과 24건 처리시간 0.022초

원발성 폐암 치료 중 발생한 Henoch-Schönlein Purpura 1예 (A Case of Henoch-Schönlein Purpura Developed during Treatment of Lung Cancer)

  • 강민수;노금엽;장영주;조수연;임경진;노희선;김혜련;김철현;이재철
    • Tuberculosis and Respiratory Diseases
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    • 제67권3호
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    • pp.234-238
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    • 2009
  • Henoch-$Sch\ddot{o}nlein$ Purpura (HSP) is a systemic vasculitis involving small vessels with the deposition of immune complexes containing IgA and C3, which is characterized by associated skin, joint, renal, and gastrointestinal manifestations. Although there were several causes such as autoimmunity, infection, and drugs, it also can be presented as a form of vasculitidies associated with malignancies. We report a case of HSP developed during treatment for non-small cell lung cancer in a 66-year-old man. Multiple purpuric skin lesions occurred in both legs after the first cycle of chemotherapy, which was diagnosed as HSP by clinical and pathologic examinations. Due to the itching sensation, topical steroid was applied and the patient was improved 3 weeks later without a scheduled change in chemotherapy.

혈관기원종양으로 오인된 귓바퀴의 색소 모기질종: 증례 보고 (Pigmented Pilomatricoma on the Ear Resembling Vascular Tumor before Surgery: A Case Report)

  • 임석범;고인창;김훈;권건영;임수연
    • 대한두경부종양학회지
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    • 제39권2호
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    • pp.31-34
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    • 2023
  • Pilomatricoma is characterized by a semi-transparent epidermis, especially pigmented pilomatricoma, containing melanocytes in basaloid cells, which are dark and purple, resembling vessel-derived skin masses. If the vascularity at doppler ultrasound is high before surgery, it may be misdiagnosed. A 10-year-old female patient visited our clinic because of a mass in the right ear triangular fossa. Ultrasonography was performed, and a vascular-origin tumor was suspected because of the high vascularity. The excised mass was diagnosed as pigmented pilomatricoma by a pathologist. Pilomatricoma is mistaken for other masses owing to its various phenotypes. A misdiagnosis can lead to misdirected strategies which can cause delayed treatment and can result in an increase in the size of the pilomatricoma, making the sequalae of surgery more complicated. For proper treatment, careful examination and evaluation are required before surgery.

Intensity-modulated radiotherapy for stage I glottic cancer: a short-term outcomes compared with three-dimensional conformal radiotherapy

  • Cho, Ick Joon;Chung, Woong-Ki;Lee, Joon Kyoo;Lee, Min-Cheol;Paek, Jayeong;Kim, Yong-Hyub;Jeong, Jae-Uk;Yoon, Mee Sun;Song, Ju-Young;Nam, Taek-Keun;Ahn, Sung-Ja;Lee, Dong Hoon;Yoon, Tae Mi;Lim, Sang-Chul
    • Radiation Oncology Journal
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    • 제37권4호
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    • pp.271-278
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    • 2019
  • Purpose: To investigate the differences in treatment outcomes between two radiation techniques, intensity-modulated radiotherapy (IMRT) and three-dimensional conformal radiotherapy (3DCRT). Materials and Methods: We retrospectively analyzed 160 (IMRT = 23, 3DCRT = 137) patients with stage I glottic cancer treated from January 2005 through December 2016. The IMRT was performed with TomoTherapy (16 patients), volumetric-modulated arc therapy (6 patients), and step-and-shoot technique (1 patient), respectively. The 3DCRT was performed with bilateral parallel opposing fields. The median follow-up duration was 30 months (range, 31 to 42 months) in the IMRT group and 65 months (range, 20 to 143 months) in the 3DCRT group. Results: The 5-year overall survival and 3-year local control rates of the 160 patients were 95.7% and 91.4%, respectively. There was no significant difference in 3-year local control rates between the IMRT and 3DCRT groups (94.4% vs. 91.0%; p = 0.587). Thirteen of 137 patients in the 3DCRT group had recurrences. In the IMRT group, one patient had a recurrence at the true vocal cord. Patients treated with IMRT had less grade 2 skin reaction than the 3DCRT group, but this had no statistical significance (4.3% vs. 21.2%; p = 0.080). Conclusion: IMRT had comparable outcomes with 3DCRT, and a trend of less acute skin reaction in stage I glottic cancer patients.

성인에서 발견된 중추성 요붕증이 합병된 폐 랑게르한스 세포 조직구증 -1예 보고- (A Case of Pulmonary Langerhans Cell Histiocytosis associated with Central Diabetes Insipidus in Adult -A case report -)

  • 유병수;이재웅;조태준;홍기우;김건일;이원용;김동규;전선영
    • Journal of Chest Surgery
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    • 제38권12호
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    • pp.866-869
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    • 2005
  • 랑게르한스 세포 조직구증(Langerhans Cell Histiocytosis)은 병적인 랑게르한스 세포의 과도한 증식과 침윤으로 생기는 병으로 병태 생리가 확실하게 밝혀져 있지 않다. 소아에서 백만명 당 3$\∼$4명의 발생률을 보이나 성인의 경우 그 발생빈도가 확실치 않다. 피부, 귀, 골수, 간, 비장, 폐, 뇌하수체-시상하부, 위장관 등 거의 모든 장기가 침범되며 뇌하수체-시상하부 축이 침범되면 요붕증이 발생한다. 원발성 폐 랑게르한스 세포 조직구증이 타장기의 침범과 동반되는 경우는 드물며, 요붕증을 동반한 경우는 더욱 드물다. 국내에서 랑게르한스 세포 조직구증 중 요붕증을 동반한 예는 다수의 보고가 있었으나 중추신경계 등 폐 이외의 장기침범이었으며 원발성 폐 랑게르한스 세포 조직구증과 동반된 중추성 요붕증은 1예가 보고되었다. 저자는 중추성 요붕증을 동반한 폐 랑게르한스 세포 조직구증을 경험하였기에 문헌고찰과 함께 보고하는 바이다.