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원발성 폐암 치료 중 발생한 Henoch-Schönlein Purpura 1예

A Case of Henoch-Schönlein Purpura Developed during Treatment of Lung Cancer

  • Kang, Min Soo (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences) ;
  • Noh, Geum Yeub (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences) ;
  • Jang, Young Joo (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences) ;
  • Cho, Soo Youn (Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences) ;
  • Rhim, Kyung Jin (Department of Dermatology, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences) ;
  • Noh, Hee Sun (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences) ;
  • Kim, Hye-Ryoun (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences) ;
  • Kim, Cheol Hyeon (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences) ;
  • Lee, Jae Cheol (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences)
  • 투고 : 2009.08.04
  • 심사 : 2009.08.19
  • 발행 : 2009.09.30

초록

Henoch-$Sch\ddot{o}nlein$ Purpura (HSP) is a systemic vasculitis involving small vessels with the deposition of immune complexes containing IgA and C3, which is characterized by associated skin, joint, renal, and gastrointestinal manifestations. Although there were several causes such as autoimmunity, infection, and drugs, it also can be presented as a form of vasculitidies associated with malignancies. We report a case of HSP developed during treatment for non-small cell lung cancer in a 66-year-old man. Multiple purpuric skin lesions occurred in both legs after the first cycle of chemotherapy, which was diagnosed as HSP by clinical and pathologic examinations. Due to the itching sensation, topical steroid was applied and the patient was improved 3 weeks later without a scheduled change in chemotherapy.

키워드

참고문헌

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