• 대한화장품학회지
• /
• 제43권4호
• /
• pp.349-355
• /
• 2017

피부색은 건강상태나 연령을 인식하는데 중요한 역할을 할 뿐만 아니라 선호하는 피부색에 따라 매력을 느끼는 기준이 되기도 한다. 다수의 소비자들은 자신의 피부색을 개선시키기 위해 화장품을 선택하기도 하며 이러한 수요에 따라 화장품의 종류는 다양해졌다. 최근에는 '하얗고 밝은 피부'에서 '건강하고 생기있어 보이는 피부' 등 안색의 선호가 다양해지고 관련 표현의 효능을 표방하는 화장품이 증가하고 있지만 '피부색(안색) 개선'에 대한 객관적인 평가 기준이 없어 본 연구에서는 피부색을 표현하는 형용사(complexion -describing adjectives, CDAs)를 선정하고 quasi $L^*a^*b^*$ 값을 이용한 통계분석 방법으로 피부색을 표현하는 형용사를 정량화하였다. CDA 7개['창백한(pale)', '깨끗한(clear)', '화사한(radiant)', '생기있는(lively)', '건강한(healthy)', '불그스름한(rosy)', '칙칙한(dull)']를 선별하였고 피부색을 평가한 경험이 있는 30명의 패널이 각각의 형용사를 밝은 피부 사진과 어두운 피부 사진의 색감에 적용하고 이를 다시 수치화하여 단어간에 통계적 유의성 여부를 확인하였다. 그 결과, 어두운 피부의 기준 이미지와 각각의 CDA를 반영한 조정 이미지, 밝은 피부의 기준 이미지와 각각의 CDA를 반영한 조정 이미지간의 quasi $L^*$, $a^*$, $b^*$ 값이 통계적 유의차를 보였다(p< 0.05). 그러나 같은 CDA를 반영한 밝은 피부와 어두운 피부간에는 통계적 유의차가 없었고, 비슷한 계열의 형용사 간에 그룹화되는 경향[(i)창백한-깨끗한-화사한 (ii)생기있는-건강한-불그스름한 (iii)칙칙한]을 확인하였다. 본 연구에서는 주관적인 느낌을 표현하는 형용사를 객관적 지표로 수치화하고 이를 통해 피부색을 평가하는 기준으로 활용할 수 있음을 제시하고자 한다.

• 한국응용약물학회:학술대회논문집
• /
• 한국응용약물학회 2007년도 Proceedings of The Convention
• /
• pp.79-92
• /
• 2007

Oxidative stress have known to be a risk factor for the degenerative processes and closely related to a lot of diseases. It is well established that antioxidants are good in protection and therapeutic means against oxidative damage. There is increasing interest in natural antioxidants and many natural antioxidants have been found and utilized as the possible protection for various diseases and skin aging. We have screened natural antioxidant agents for cosmeceuticals, nutraceuticals, and drugs as therapeutic and preventive means against oxidative stress, and have developed a number of novel antioxidants from various natural sources. A novel melanin synthesis inhibitor, Melanocin A, isolated from the metabolite of a fungal strain Eupenicillium shearii F80695 inhibited mushroom tyrosinase and melanin biosynthesis of B16 melanoma cells with $IC_{50}$ value of 9.0 nM and MIC value of $0.9\;{\mu}M$, respectively. Melanocin A also exhibited potent antioxidant activity by scavenging of DPPH and superoxide anion radicals. UV was found to increase the level of hydrogen peroxides and other reactive oxygen species (ROS) in skin tissues. This increase in ROS may not only alter the structure and function of many genes and proteins directly but may also modulate their expressions through signal transduction pathways and, ultimately, lead to skin damage. We investigated the effect of Melanocin A on UV-induced premature skin aging. Firstly, the effect of Melanocin A on UV-induced matrix metalloproteinase (MMP)-9 expression in an immortalized human keratinocyte cell line, HaCaT in vitro was investigated. Acute UV irradiation induced MMP-9 expression at both the mRNA and protein levels and Melanocin A suppressed this expression in a dose-dependent manner. We then investigated UV-induced skin changes in hairless mice in vivo by Melanocin A. Chronic exposure of hairless mouse dorsal skin to UV increased skin thickness and induced wrinkle formation and the gelatinase activities of MMP-2 and MMP-9. Moreover, Melanocin A significantly suppressed UV-induced morphologic skin changes and MMP-2 and MMP-9 expression. These results show that Melanocin A can prevent the harmful effects of UV that lead to skin aging. Therefore, we suggest that Melanocin A should be viewed as a potential therapeutic agent for preventing and/or treating premature skin aging. Terrein is a bioactive fungal metabolite isolated from Penicillium species. Terrein has a relatively simple structure and can be easily synthesized. However, the biologic effects of terrein are comparatively unknown. We found for the first time that terrein potently inhibit melanin production in melanocytes and has a strong hypopigmentary effect in a spontaneously immortalized mouse melanocyte cell line, Mel-Ab. Treatment of Mel-Ab cells with terrein (10-100 mM) for 4 days significantly reduced melanin levels in a dose-dependent manner. In addition, terrein at the same concentration also reduced tyrosinase activity. We then investigated whether terrein influences the extracellular signal-regulated protein kinase (ERK) pathway and the expression of microphthalmia-associated transcription factor (MITF), which is required for tyrosinase expression. Terrein was found to induce sustained ERK activation and MITF down-regulation, and luciferase assays showed that terrein inhibits MITF promoter activity in a dose-dependent manner. To elucidate the correlation between ERK pathway activation and a decreased MITF transcriptional level, PD98059, a specific inhibitor of the ERK pathway, was applied before terrain treatment and found to abrogate the terrein-induced MITF attenuation. Terrein also reduced the tyrosinase protein level for at least 72 h. These results suggest that terrain reduces melanin synthesis by reducing tyrosinase production via ERK activation, and that this is followed by MITF down-regulation.

• 한국축산식품학회지
• /
• 제35권1호
• /
• pp.35-40
• /
• 2015

Super- and sub-critical water treatments have been of interest as novel methods for protein hydrolysis. In the present study, we studied the effect of sub-critical water (Sub-$H_2O$, $300^{\circ}C$, 80 bar) treatment as well as super-critical water (Super-$H_2O$, $400^{\circ}C$, 280 bar) treatment on the physicochemical properties of porcine skin (PS), which has abundant collagen. Porcine skin was subjected to pre-thermal treatment by immersion in water at $70^{\circ}C$, and then treated with sub- or super-critical water. Physicochemical properties of the hydrolysates, such as molecular weight distribution, free amino acid content, amino acid profile, pH, color, and water content were determined. For the molecular weight distribution analysis, 1 kDa hydrolyzed porcine skin (H-PS) was produced by Super-$H_2O$ or Sub-$H_2O$ treatment. The free amino acid content was 57.18 mM and 30.13 mM after Sub-$H_2O$ and Super-$H_2O$ treatment, respectively. Determination of amino acid profile revealed that the content of Glu (22.5%) and Pro (30%) was higher after Super-$H_2O$ treatment than after Sub-$H_2O$ treatment, whereas the content of Gly (28%) and Ala (13.1%) was higher after Sub-$H_2O$ treatment. Super-$H_2O$ or Sub-$H_2O$ treatment affected the pH of PS, which changed from 7.29 (Raw) to 9.22 (after Sub-$H_2O$ treatment) and 9.49 (after Super-$H_2O$ treatment). Taken together, these results showed that Sub-$H_2O$ treatment was slightly more effective for hydrolysis than Super-$H_2O$ was. However, both Sub-$H_2O$ and Super-$H_2O$ treatments were effective processing methods for hydrolysis of PS collagen in a short time and can be regarded as a green chemistry technology.

• 패션비즈니스
• /
• 제27권3호
• /
• pp.132-149
• /
• 2023

This study aims to analyze Instagram hashtags based on big data to investigate changes in consumer trends and perceptions of vegan fashion, and to derive strategies for revitalizing vegan fashion brands based on derived results. Among social media, Instagram was selected as a collection channel, and Instagram hashtags for 'Vegan Fashion' were collected from July 1, 2021 to December 31, 2021. After conducting semantic network analysis with the Ucinet 6 program based on the collected data, the CONCOR analysis on vegan fashion showed the following four clusters: 'Veganism practiced with fashion', 'Bag type of vegan fashion brand', 'Sharing vegan fashion', and 'Diversification of eco-friendly products'. Analysis results showed that the Instagram hashtag for vegan fashion confirmed the MZ generation's increased interest in vegan fashion and their thoughts to recommend and share frequently used items or brand products to people around them. CONCOR analysis of vegan fashion brands showed the following four groups: 'Differentiating the material of vegan bags', 'Eco-friendly products of vegan fashion brands', 'Interest in vegan shoes', and 'Donation campaign of vegan fashion brands'. CONCOR analysis on Meaningout showed the following four clusters: 'MZ Generation's Meaningout Start-up', 'Recommendation Platform for Skin Products', 'Value Consumption Trend for Eco-friendly Clothing', and 'Interest in Eco-friendly Packaging'. The results of this study on vegan fashion, a practical eco-friendly movement that can require changes in social responsibility and perception as issues that directly affect animals, the environment, and humans, are expected to provide basic data to help domestic vegan fashion brands develop marketing strategies.

• 한국응용과학기술학회지
• /
• 제40권4호
• /
• pp.724-732
• /
• 2023

본 연구에서는 코로나 이후 색조화장품 시장의 소비자들의 온라인 관심 정보에 대한 자료 수집을 통하여 색조화장품 정보 검색의 특성과 텍스트 마이닝 분석 결과에 나타난 코로나 이후 색조화장품 시장의 주요 관심정보들을 분석하고자 하였다. 실증분석에서는 "색조화장품" 이라는 단어를 포함하는 뉴스, 블로그, 카페, 웹페이지 등의 모든 문서들을 분석 대상으로 텍스트 마이닝을 수행하였다. 분석 결과 코로나 이후 색조화장품에 대한 온라인 정보 검색은 주로 구매 정보와 피부와 마스크 관련 화장법 등에 관한 정보와 관심 브랜드와 행사 정보 등의 주요 토픽이 주를 이루고 있었다. 결과적으로 코로나 이후 색조화장품 구매자들은 적극적인 온라인 정보 검색을 통하여 제품 가치와 안전성, 가격 혜택, 매장 정보 등의 구매 정보에 더욱 민감하게 될 것이므로 이에 대한 대응전략이 요구된다.

• 소음진동
• /
• 제7권4호
• /
• pp.613-620
• /
• 1997

Steady and unsteady flows between rotating cylinders are of interest on lubrication, convective heat transfer and flow-induced vibration in large rotating machinery. Steady rotating flow is generated by rotating cylinder with constant velocity while the unsteady rotating flow by oscillating cylinder with homogeneoysly oscillating velocity. An analytical method is developed based on the simple radial coordinate transformation for the steady and unsteady rotating flows in concentric annulus. The governing equations are simplified from Navier-Stokes equatins. Considering the skin friction based on the radial variation of circumferential flow velocity, the torques acting on the fixed and the rotating cylinder are evaluated in terms of added-inertia and added-damping torque coefficients. The coefficients are found to be influenced by the oscillatory Reynolds number and the radius ratio of two cylinders; however, the effect of the oscillatory Reynolds number on the coefficients is minor in case of relatively low radius ratio.

• Journal of Yeungnam Medical Science
• /
• 제24권2호
• /
• pp.97-106
• /
• 2007

Functional electrical stimulation (FES) has developed over the last 35 years to become a scientifically, technologically and clinically recognized field of interest in clinical medicine. FES has been applied to locomotion, grasping, ventilation, incontinence, and decubitus healing. However, all of these achievements illustrate the initial applications of FES; its true potential has not yet been realized. Recently, FES systems, which are miniaturized stimulation devices, have been utilized in the clinical setting. However, because the stimulating electrodes of the current FES devices are percutaneous electrodes, which are susceptible to wire breakage, and skin infection an implantable FES stimulating electrode has been introduced in the U.S. and Japan. In the present study, an external power supply method using radio frequency (RF) coupling and data transmission was developed for the control of the implantable FES device. In addition, we review the current understanding of FES devices and their application in clinical medicine.

• 복식
• /
• 제67권1호
• /
• pp.95-109
• /
• 2017

The objectives of this study are to develop a cosmetic involvement scale focusing on Korean men in their 20s and 30s, verify its validity and examine the characteristics of this group. The results of this study's analyses showed that cosmetic involvement scale could be classified into 5 factors: 'trend & interest involvement', 'prestige sensitivity involvement', 'price and value involvement', 'skin involvement,' and 'obligatory involvement'. Also the cosmetic involvement of the target group was classified into 'amusing high-involvement group', 'rational low-involvement group', and 'obligatory high-involvement group'. This study has significance in showing differences of cosmetic involvement factors by gender and proposing a cosmetic involvement scale of Korean men in their 20s and 30s, which has taken men's distinctiveness into consideration.

• 패션비즈니스
• /
• 제18권5호
• /
• pp.99-115
• /
• 2014

This thesis aimed examine the relationship between the health characteristics (musculoskeletal, respiratory, skin, digestive, nervous mental system) of cosmetologists and their demographic, health management, and working environment characteristics to help cosmetologists maintain a healthy work life while solving health problems. These research was carried out via survey and statistics analysis. A total of 279 cosmetologists living in Seoul, Kyeongkido, and Choongchungdo from 8 July to 30 August, 2014 were surveyed. Frequency, mean, factor, and regression analysis were carried out on the data with SPSS(V. 14). The results were as follows; (1) a relationship between health & the demographic characteristics of gender was found;- (2) health and the health management characteristics of interest in health problem prevention, active exterior health support, muscular exercise, interior health support, and stress management were found to be related;- (3) health and working the environment characteristics of working time per day, and work days per week were related.

• 한국지반공학회:학술대회논문집
• /
• 한국지반공학회 2002년도 봄 학술발표회 논문집
• /
• pp.583-588
• /
• 2002

As environmental problem in course of construction has been a matter of interest, noise and vibration in the process of piling are considered as a serious problem. For this reason, the use of SIP method inserting pile as soon as boring and cement grouting is rapidly increasing for preventing vibration and noise. But a resonable bearing capacity formula for SIP method does not exit and even the standard specification for domestic condition isn't formed, though the lateral friction between cement paste and the ground does an important role and boring depth largely influences to the design bearing capacity, applying the SIP method . Therefore, the lateral friction was analyzed after the direct shear test worked with the lateral face of SIP and the soil.