• Archives of Reconstructive Microsurgery
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• v.20 no.1
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• pp.26-31
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• 2011

Purpose: We compared wound healing between the conventional tie-over dressing and silicone sheeting after skin grafting in patients with skin defects. Materials and Methods: Of a total of 30 cases of skin defects, 15 underwent conventional tie-over dressing and the remaining 15 underwent silicone sheeting skin grafting, we compared hematoma formation and infection status between the 2 techniques 1 and 2 weeks after operation Results: Hematoma was not observed in all cases. The wound infection rate decreased in silicone group. Conclusions: Silicone sheeting skin graft may be helpful in reducing wound infection.

• Journal of Korean Neurosurgical Society
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• v.62 no.1
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• pp.123-129
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• 2019

Objective : Ventriculoperitoneal (VP) shunt surgery is a common and effective treatment for hydrocephalus and cerebrospinal fluid disorders. Infection remains a major cause of morbidity and mortality after a VP shunt. There is evidence that a deep skin flora microbiome may have a role to play in post-operative infections. In this technical note, we present a skin preparation technique that addresses the issue of the skin flora beyond the initial incision. Methods : The patient is initially prepped, as standard, with. a single layer of 2% CHG+70% isopropyl alcohol. The novel stage is the 'double incision' whereby an initial superficial incision receives a further application of povidone-iodine prior to completing the full depth incision. Results : Of the 84 shunts inserted using the double-incision method (September 2015 to September 2016), only one developed a shunt infection. Conclusion : The double incision approach to skin preparation is a unique operative stage in VP shunt surgery that may have a role to play in reducing acute shunt infection.

• The Journal of the Korea Contents Association
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• v.14 no.12
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• pp.808-817
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• 2014

Purpose: This study was to investigate the recognition of skin infection (RSI) and management practice (MP) on caregivers in geriatric hospital. Methods: The subjects were 209 caregivers who work at geriatric hospital in G city and J do. Data were analyzed with ${\chi}^2$-test, t-test. and ANOVA using SPSS 18.0 program. Results: Prevalence rate of caregivers' skin diseases was 76.6%. Diagnosis of Skin disease was contact dermatitis 42.5%, scabies 26.9%, and skin xerosis 25.0%. The Mean RSI score was 3.81 and MP was 4.12. In addition, MP was significantly different by number of bed hospitals (F=4.63, p=.011) and number of caring patients (F=2.67, p=.049). Conclusion: This study will be a useful on continuing education for caregivers and basis for the guidance of medical infection control standards development.

• Archives of Plastic Surgery
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• v.35 no.2
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• pp.134-138
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• 2008

Purpose: In a diabetic foot ulcer, superficial fungal infection of the foot may disrupt the skin integrity and provide an avenue for bacterial infection. The prevalence of fungal infection in diabetic foot ulcer has been reported as 12-30% in Caucasian patients. However, no data are available for Korean patients. The purpose of the study was to examine the prevalence of fungal infection in diabetic foot patients admitted in our clinic. Methods: This study included consecutive 30 diabetic foot ulcer patients(24 males and 6 females) admitted from May 2007 to July 2007. The mean age was 60.5 years. All patients underwent mycological examination including direct microscopic examination in KOH and culturing on slants and tubes with Sabouraud's glucose agar. Results: Clinical signs of presumed fungal infection, which were examined by dermatologists, were found in all patients included in this study. Direct microscopic examination was positive for the specimens of the skin and the toenails in 28(93.3%) and 25(83.3%) patients, respectively. In addition, culture result was positive for the specimens of the skin and the toenails in 5(16.73%) and 7(23.3%) patients, respectively. Conclusion: The prevalence of fungal infection in diabetic foot ulcer patients admitted in our clinic is much higher than that in Caucasian patients(83.3-93.3% vs 12-30%).

• Journal of Acupuncture Research
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• v.38 no.2
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• pp.159-164
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• 2021

Background: Cupping is widely used in Korean medicine, but there is a risk of bacterial infection if the suction pump (used for inducing negative pressure) and the patients' skin are not separated. This study aimed to investigate the effect of layer cupping by comparing the pressure changes between layer cupping and conventional cupping. Methods: To evaluate pressure changes the study was designed with 3 types of conditions applied to a skin model: (1) a Dongbang cup with a manual or motor suction pump (conventional cupping); (2) layer cupping with 2 Dongbang cups; and (3) layer cupping with a cup made by 3D printing and a Dongbang cup. Results: When a manual suction pump was used (conventional cupping), the pressure did not decrease steadily, and in 1 section there was an increase in pressure. When layer cupping was used, the pressure in the lower cup (which would be directly applied to the patient's skin), decreased steadily. Conclusion: In the pressure change graph for layer cupping in this skin model, the pressure in the lower cup (which would be placed on the patient's skin) steadily decreased, and reached equilibrium. Therefore, the layer cupping model may help to reduce the risks of bacterial infection.

• Toxicological Research
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• v.13 no.1_2
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• pp.157-160
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• 1997

The primary skin and eye irritancy of the combined vaccine (KGCC-95VI) for the prophylaxis against Japanese encephalitis and Hantaan virus infection recently developed by Korea Green Cross Corporation was investigated. The KGCC-95VI was applied to the back skins of the New Zealand White rabbits. The rabbits were observed for 72 hours and did not exhibit erythema, eschar and edema. The eyes of the rabbits were exposed to the KGCC-95VI. The rabbits were observed for 7 days and did not exhibit any ocular findings on cornea, iris and conjuntivae. The KGCC-95VI is considered not to have the primary skin and eye toxicity in rabbits.

• Journal of Microbiology and Biotechnology
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• v.19 no.6
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• pp.622-628
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• 2009

In the present study, the therapeutic potential of purified and well-characterized bacteriophages was evaluated in thermally injured mice infected with Klebsiella pneumoniae B5055. The efficacy of five Klebsiella phages (Kpn5, Kpn12, Kpn13, Kpn17, and Kpn22) was evaluated on the basis of survival rate, decrease in bacterial counts in different organs of phage-treated animals, and regeneration of skin cells as observed by histopathological examination of phage-treated skin. Toxicity studies performed with all the phages showed them to be non-toxic, as no signs of morbidity and mortality were observed in phage-treated mice. The results of the study indicate that a single dose of phages, intraperitoneally (i.p.) at an MOI of 1.0, resulted in significant decrease in mortality, and this dose was found to be sufficient to completely cure K. pneumoniae infection in the burn wound model. Maximum decrease in bacterial counts in different organs was observed at 72 h post infection. Histopathological examination of skin of phage-treated mice showed complete recovery of burn infection. Kpn5 phage was found to be highly effective among all the phages and equally effective when compared with a cocktail of all the phages. From these results, it can be concluded that phage therapy may have the potential to be used as stand-alone therapy for K. pneumoniae induced burn wound infection, especially in situations where multiple antibiotic-resistant organisms are encountered.

• Journal of Mycology and Infection
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• v.23 no.4
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• pp.99-104
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• 2018

Background: Trichophyton verrucosum (T. verrucosum) is a zoophilic dermatophyte that causes ringworm in cattle and is prevalent worldwide. This dermatophyte may be responsible for various conditions, especially inflammatory skin lesions. Objective: In this study, we aimed to investigate the changes in the clinical and epidemiological characteristics of T. verrucosum infections in southeastern Korea. Methods: A total of 34 patients who visited the Catholic Skin Clinic and the Kyungpook National University Hospital in Daegu, Korea from 2005 to 2017 were diagnosed with T. verrucosum infection. The diagnosis was confirmed using fungal culture. The data were based on a retrospective survey of the medical records. Results: The annual incidence of T. verrucosum infection was very low. There was no difference in the sexual incidence. T. verrucosum infection was most common among subjects in their fifties and sixties. The highest incidence was during the month of September. The arm was most frequently involved, followed by the face. This infection was predominant in patients living in rural areas. Conclusion: These clinicoepidemiological findings provide useful information for understanding the changes in the infection caused by T. verrucosum. In particular, it was interesting to note that the incidence was very low, majority of the affected subjects were in their fifties and sixties, and the most commonly affected site was the arm.

• Korean Journal of Occupational Health Nursing
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• v.29 no.3
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• pp.192-201
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• 2020

Purpose: This study aims to conduct an integrated literature review of infection control studies conducted by nursing care workers in long-term care facilities in Korea. Methods: Through the domestic search engines RISS and KISS, seven articles were selected by searching for theses and academic journals published in Korea from 2008 to January 2020. Results: In total, six research studies and one intervention study out of seven studies were analyzed. Measurement tools for examining the knowledge and performance of infection-related care workers consisted of skin infection, aspiration pneumonia, urinary tract infection, and hand hygiene. Factors affecting nursing care workers' infection management performance were infection management knowledge, education level, health status, and importance awareness. Conclusion: This study showed it is necessary to develop a tool that can accurately measure nursing care workers' infection management knowledge and performance. In addition, it is necessary to develop an intervention program for nursing care workers' infection control.

• Journal of Korean Public Health Nursing
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• v.2 no.2
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• pp.45-61
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• 1988

Clonorchiasis should be realized as an important public health problems in Korea by their wide distribution, high prevalence rate and heavy infection intensity. This study was designed to obtain the infection rate, contributing factors as well as the behavior of infected persons among the factory workers in Pohang area where that parasite still remains as a problem. Study was undertaken from September '86 to October '87. Clonorchiasis skin test was performed for 3180 factory workers, and stools of skin test positive reactors were examined. Praziquantel was prescribed to stool examination positive persons for clonorchis sinensis ova. After one year. stool examination was repeated for them who received medicine. At the same time. a structured questionnaire was given and the results were analyzed and compared with control group. The results of this study are summarized as follows; 1. The infection rate of Clonorchis sinensis. 1) Clonorchiassis skin test positive rate was $26.2\%$ (834/3180). 2) Stool(Clonorchis sinensis ova) positive rate among skin test positive reactors was $21.6\%$ (129/598) All 129 infected persons were male. 2. Contributing factors of Clonorchis sinensis infection. 1) The chance of infection was higher in low-educated peple(p<0.01) 2) Stool(Clonorchis sinensis ova)positive rate was higher among the persons who reside near the riverside now(p<0.01), or among the persons who long history of riverside residence(p<0.01) 3) The infection rate was higher in thoes who like sliced raw fresh water fishes than in those who like cooked fishes(p<0.05). 4) Correct answering rate for questions about the cause and route of Clonorchis sinensis infection was low in infected persons. 5) The infection rate was lower among those who had experience of previous clonorchiasis test(p<0.01). 6) Family members of infected persons show higher rates of infection(p <0.01). 3. Treatment effect and compliance of infected person to treatment. 1) After one year, negative stool conversion rate was $85.4\%$. 2) $70.8\%$ of infected persons took the medicine; Only $3.1\%$ of them consulted to physician to know the medication effect; As many as $29.4\%$ of them continued to consume raw fresh water fishes. As a conclusion, City of Pohang area, Hyung San River in the center, is an endemic area of clonorchiasis. Current clonorchiasis control system seemed to be ineffective; many of the skin test positive group did not submitted their stool for examination; only $70.8\%$ of infected persons took the medicine even though the drugs were given free of charge; $29.4\%$ continued to consume raw fresh water fishes after taking medicine. Therefore. proper education program should be provided to improve the compliance to treatment. Follow-up for infected cases is mandatory to prevent waste of restricted budget.