• Title/Summary/Keyword: Skin function

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A Human Engineering Study of Clothing in an Environmental Aspect (I) - Based on the Skin Temperature after Physical Exercise of Human Body - (환경요소면으로 본 의복의 인간공학적 연구 (I) - 인체동작후의 피부온 변화를 중심으로 -)

  • 이전숙
    • Journal of the Korean Home Economics Association
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    • v.20 no.2
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    • pp.65-71
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    • 1982
  • Comfort concept of heating and cooling between body and environment is modified by the clothing. So were can say the clothing is one of the environment. To maintain“pleasantness”, clothing must have the elements of comfort and function. This study carried out for the 1st step to describe the relation between clothing and the human body I aspect to the emvironmental elements of temperature and working part of the body. Observations of skin temperature were taken on young adults female subjects in training wear and the skin temperature was measured onto 9 points of the body while taking part in two physical exercise, with Rawing machine and Bicycle ergometer. The results obtained are as follows; 1. The skin temperature after physical exercise is lower than that after repose. 2. After physical exercise of the lower part of the body, the skin temperature is less than that after physical exercise of the upper part of the body. 3. After physical exercise of the upper part of the body, skin temperature of the lower part of the body rises a little, and vice versa.

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Classification of Make-up (현대 메이크 업의 분류)

  • Shin, Seong-Yoon;Shin, Kwang-Seong;Nam, Soo-Tai
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2021.05a
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    • pp.344-345
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    • 2021
  • In this paper, the classification and types of makeup were newly written appropriately for the present day. And the exact meaning of makeup was newly designated. Make-up protects the skin from various external environmental changes. In addition, it has a beautification function that hides many flaws in our skin and makes it beautiful.

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Theoretical Model for the Electrical Resistance of Skin (피부의 전기적 저항에 대한 이론적 모델)

  • Oh, Seaung-Youl
    • Journal of Pharmaceutical Investigation
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    • v.26 no.3
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    • pp.207-213
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    • 1996
  • The kinetic change of electrical resistance of hairless mouse skin as a function of ionic strength of the bathing medium was determined from impedance measurements. After increasing (decreasing) the ionic strength of the bathing medium, resistance decreased (increased) continuously with time, finally reaching an equilibrium value. We have modelled this process, using nonsteady-state diffusion kinetics. The results show semi-quantitative correlation between theoretically derived and experimentally obtained values. Overall, this work provides further mechanistic insight into ion-conduction through the skin.

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Effects of Skin Mobilization on Pain and Joint Range Improvement in Patients with Axillary Web Syndrome: A Single Case Report

  • Choi, Suhong;Lee, Sangyeol
    • Physical Therapy Rehabilitation Science
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    • v.10 no.2
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    • pp.112-115
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    • 2021
  • Objective: This study was conducted to apply skin mobilization to patients with Axillary web syndrome following breast cancer resection and to see the resulting changes in pain and joint range of motion. Design: Single case study,pre-post comparison. Methods: The subject was a female patient in her 40s who performed a mastectomy after being diagnosed with breast cancer, and then complained of uncomfortable pain from the shoulder joint to the axilla and limited range of motion. To implement a skin mobilization, the palms were adhered to the inner half of the arm, the arms were raised to a pain-free extent, and skin mobilization was performed. The skin was pulled in the direction of axilla and kept for 5 seconds 10 times for a total of 2 sets. Immediate changes in range of motion and pain were identified. Results: Following skin mobilization, there was an immediate increase in range of motion (pre 116°, post 140°) and a decrease in pain (NRS pre 5, post 2). And also uncomfortable pain, which is hard to define in words, also seems to have improved. Conclusions: Skin mobilization, which considers skin mobility for patients with Axillary web syndrome, can be considered for improving range of motion and restoring function in patients with pain due to fibrous bands around veins and lymphatic vessels, and is recommended as a new intervention method not used as a conventional treatment.

Research Trends in the Development of Cosmetic Ingredients for Skin Barrier Improvement

  • Hyung-Bum Park;Jeong-Yeon Park
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.6
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    • pp.1445-1453
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    • 2023
  • In 2022, the domestic production performance of functional cosmetics in South Korea reached 4.6 trillion won, accounting for 33.85% of the total cosmetics production. The number of functional cosmetics reviewed increased by about 7.5% from the previous year, totaling 974 items. Especially with the increasing importance of the skin barrier function due to skin sensitivity caused by various environmental pollutants, domestic cosmetic companies are showing interest in the development of new ingredients and products related to this area. This study aims to analyze academic research trends related to in vitro experiments for the development of cosmetics improving the skin barrier, to provide practical information for the cosmetic industry. The findings are as follows: Academic research mainly focused on the efficacy of natural ingredients in improving the skin barrier, but there is a significant lack of quantitative accumulation of research. For the development of skin barrier-improving cosmetic ingredients, efficacy evaluation indicators were set, including hyaluronic acid production, expression of filaggrin gene, loricrin, formation of cornified envelope (CE), and expression of ceramide synthesis enzyme genes. Moreover, effective cosmetic ingredients for improving the skin barrier included lemongrass and perilla leaf extracts, flavonoids, Lactococcus lactis subsp. lactis, Exosomelike Nanovesicles derived from apple callus, Eleutherococcus sessiliflorus, Acanthopanax sessiliflorus, Eleutherococcus gracilistylus, Acer okamotoanum extracts, Aloe vera adventitious root extract, ethanol extract of Aruncus dioicus, and organic solvent fraction of Dracocephalum argunense.

A Study of Skin Biophysical Parameters and Biomarkers related to the Anatomical Site and Age in Korean Women (한국 여성의 피부 부위 및 연령에 따른 피부 측정 인자와 생물 인자 연구)

  • Cho, Seok-Cheol;Nam, Gaewon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.41 no.4
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    • pp.413-420
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    • 2015
  • The skin is one of the largest organs in our body and participates in many of the human organism's physiological and pathological events. Skin function were known for self-maintenance and self-repair, mechanical and chemical stress protection, protection against UV and environmental pathogenic micro-organisms, production of vitamin D, and social and psychological function through the physical aspect. The aim of this study was to evaluate the variation of biophysical parameters and to find relation with skin biomarkers in different anatomical site and age in Korean women. About 70 healthy volunteers in age range 20 to 49 were participated in this test. Test areas were the forearms and the cheek. Investigation to determine biophysical parameters on human skin, was carried out using various non-invasive methods. For analysis to skin biomarkers, we studied to examine various biomarkers for the quantitative determination of cortisol, fibronectin, keratin-1, 10, and 11, involucrin, and keratin-6 in human face and forearm. And we measured to skin biophysical parameters for skin anatomical site and age difference with non-invasive methods. As results of measuring site, some parameters were have following significant difference, stratum corneum hydration, trans epidermal water loss and skin color (L and a value). As results of age difference, skin colors were had only significant difference with age. For cortisol, keratin-6, fibronectin, keratin-1, 10, 11 contents, there were no significant difference in age and site. However, involucrin level in the cheeks were the highest for age group 30 ~ 39 compared to other age groups. These results suggest that in individual skin condition may explain detailed skin state variation.

Face Tracking Using Face Feature and Color Information (색상과 얼굴 특징 정보를 이용한 얼굴 추적)

  • Lee, Kyong-Ho
    • Journal of the Korea Society of Computer and Information
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    • v.18 no.11
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    • pp.167-174
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    • 2013
  • TIn this paper, we find the face in color images and the ability to track the face was implemented. Face tracking is the work to find face regions in the image using the functions of the computer system and this function is a necessary for the robot. But such as extracting skin color in the image face tracking can not be performed. Because face in image varies according to the condition such as light conditions, facial expressions condition. In this paper, we use the skin color pixel extraction function added lighting compensation function and the entire processing system was implemented, include performing finding the features of eyes, nose, mouth are confirmed as face. Lighting compensation function is a adjusted sine function and although the result is not suitable for human vision, the function showed about 4% improvement. Face features are detected by amplifying, reducing the value and make a comparison between the represented image. The eye and nose position, lips are detected. Face tracking efficiency was good.

Alterations of stratum corneum associated with aging in hairkless mouse (노화에 따른 무모 생쥐의 각질층 상태 변화)

  • 박선규;김영득
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.22 no.1
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    • pp.27-39
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    • 1996
  • Recently, in vitro stratum curneum model was a useful tool to evaluate the skin condition such as tranespidermal water loss, skin hydration and etc.. In this study to evaluate the alteration of SC with aging in hairless mouse, we measured TEWL using in vitro SC model, SC lipid, and outer corneocytes area. Although the total SC lipid was rich about 30% in 8 week old mouse compared with that of 82 week old mouse, the TEWL values were higher in the former than that of the latter. The outer corneocytes area was 559 $\pm$ 65 $mu extrm{m}$2 in 8 week old mouse and 755 $\pm$ 56 ${\mu}{\textrm}{m}$2 in 82 week old mouse. So the barrier function was reinforced with aging. This result suggested that the reinforced barrier function is one of the defense systems against the outer enviornment and the decreased skin function with aging.

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Compound K improves skin barrier function by increasing SPINK5 expression

  • Park, No-June;Bong, Sim-Kyu;Lee, Sullim;Jung, Yujung;Jegal, Hyun;Kim, Jinchul;Kim, Si-Kwan;Kim, Yong Kee;Kim, Su-Nam
    • Journal of Ginseng Research
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    • v.44 no.6
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    • pp.799-807
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    • 2020
  • Background: The skin acts as a barrier to protect organisms against harmful exogenous agents. Compound K (CK) is an active metabolite of ginsenoside Rb1, Rb2 and Rc, and researchers have focused on its skin protective efficacy. In this study, we hypothesized that increased expression of the serine protease inhibitor Kazal type-5 (SPINK5) may improve skin barrier function. Methods: We screened several ginsenosides to increase SPINK5 gene promoter activity using a transactivation assay and found that CK can increase SPINK5 expression. To investigate the protective effect of CK on the skin barrier, RT-PCR and Western blotting were performed to investigate the expression levels of SPINK5, kallikrein 5 (KLK5), KLK7 and PAR2 in UVB-irradiated HaCaT cells. Measurement of transepidermal water loss (TEWL) and histological changes associated with the skin barrier were performed in a UVB-irradiated mouse model and a 1-chloro-2,4-dinitrobenzene (DNCB)-induced atopic dermatitis-like model. Results: CK treatment increased the expression of SPINK5 and decreased the expression of its downstream genes, such as KLKs and PAR2. In the UVB-irradiated mouse model and the DNCB-induced atopic dermatitis model, CK restored increased TEWL and decreased hydration and epidermal hyperplasia. In addition, CK normalized the reduced SPINK5 expression caused by UVB or DNCB, thereby restoring the expression of the proteins involved in desquamation to a level similar to normal. Conclusions: Our data showed that CK contributes to improving skin-barrier function in UVB-irradiated and DNCB-induced atopic dermatitis-like models through SPINK5. These results suggest that therapeutic attempts with CK might be useful in treating barrier-disrupted diseases.

Screening of Xerosis Inhibitor from Seaweed Extracts Using HaCaT Keratinocyte

  • Yoon, Seung-Je;Khan, Mohammed N.A.;Kang, Ji-Young;Nam, Ju-Hyun;Ahn, Dong-Hyun;Hong, Yong-Ki
    • Journal of Marine Bioscience and Biotechnology
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    • v.4 no.1
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    • pp.31-34
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    • 2010
  • The primary function of the skin is to protect the body from the unwanted environmental influences. The outermost layer of the skin is stratum corneum which consists of corneocytes surrounded by lipid regions. Ceramides covalently bound to keratinocytes are essential for the barrier function of the skin, which can be disturbed in the disease, like xerosis. Xerosis is an abnormal dryness of the skin which reduced the thickness of stratum corneum and ceramide content decreasing with age. In this study, 36 seaweed extracts have been tested for screening of xerosis inhibitory agent by in vitro HaCaT keratinocyte assay. Ishige sinicola and Helminthocladia australis induced the significant amount of ceramide-like substance I in HaCaT keratinocyte among the tested seaweed extracts. Sargassum fulvellum, Chondrus ecellatus and Gigartina tenella also induced the ceramide-like substance I whereas Helminthocladia australis and Pachymeniopsis elliptica induced the ceramide-like II from HaCaT keratinocyte.

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