• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4577-4581
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• 2013

Background: The objective of this study was to determine the practice of skin cancer prevention among Malaysian road traffic police officers. Materials and Methods: This cross-sectional study involved 202 Malaysian Road Police Traffic officers. Inclusion criteria were those officers who work wearing white uniform regulating traffic. The survey took place at the Police Traffic Station, Jln Tun H.S. Lee, Kuala Lumpur, the main Head Quarters of Malaysian's Traffic Department where almost 600 police traffic officers are employed. The police traffic officers are given the task to take care of the traffic from the main office of the police station, then, according to the task, the officers drive to their given location for their duty. Each task is approved by the Chief Traffic Inspector of Kuala Lumpur. Data collected in this study were analyzed using SPSS 13, with the T-test for univariate analysis and multiple linear regression for multivariate analysis. Results: A total of 202 road traffic police officers participated. The majority were older than 30 years of age, male, Malay, married, with secondary education, with monthly income more than 2000 Ringgit Malaysia (66.3%, 91.1%, 86.6%, 84.7%, 96%, 66.3%; respectively). Regarding the practice of skin cancer prevention, 84.6% of the study participants were found to wear hats, 68.9% sunglasses and 85.6% clothing that covering most of the body but only 16.9% used a sunscreen when they were outdoors. When analysis of the factors that influenced the practice of skin cancer prevention was performed, univariate analysis revealed that gender, age and monthly income significantly influenced the practice of skin cancer prevention. For multivariate analysis, gender, monthly income and race significantly influenced the practice of using sunscreen among road traffic police officers (p<0.001, p=0.019, p=0.027; respectively). Conclusions: The practice of skin cancer prevention among the traffic police officers showed good practices in terms of wearinga hat, sun glasses and clothing that covers most of the body. However, the study revealed a poor practice of the use of sunscreen. The factors that influence the practice of sunscreen use were found to be gender, income, and race. The study suggests that more awareness campaign among traffic police officers is needed. Providing sunscreen for free for police traffic officers should be considered by the Police authorities.

• Tribology and Lubricants
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• v.28 no.6
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• pp.297-302
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• 2012

We conducted 3D elastic contact analysis of a sharkskin surface pattern for the characteristic assessment of biomimetic shark skin structure pattern for engineering applications. Rough sharkskin surfaces of similar size with real shark skin scales are generated numerically. Under the assumption of the contact of a plate on the generated sharkskin surface, contact performances such as contact pressure, real contact area, and surface separation are evaluated.

• Proceedings of the Korean Geotechical Society Conference
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• 2003.03a
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• pp.153-160
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• 2003

While the interests on the environmental problem during the construction are increasing, the use of low noise-vibration auger-drilled pilling is increasing to solve noise and vibration problem in pilling. Therefore, in Korea, SIP(Soil-Cement Injected Precast Pile) method is mainly used as auger-drilled pilling. However, there is no proper design criteria compatible with the ground condition of Korea, so which is most wanted. To improve and supplement this situation, direct shear tests between SIP pile skin interface and soil were executed on various conditions. Through the analysis of test results, skin resistance characteristics of SIP were investigated thoroughly. Also, the nonlinear unit skin resistance capacity model with SM, SC soil were suggested.

• Journal of the Korean housing association
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• v.14 no.3
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• pp.119-126
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• 2003

The purpose of this study is to evaluate the natural ventilation performance for variable external wind speed as a preliminary step to determining the seasonal operating modes of the Double-skin Facade System applied to apartment buildings. For this purpose, two simulation programs are used to compare the Double-Skin Facade System with the Double Sash Window. First, TAS is used to plan a schedule for natural ventilation during the intermediate season and to analyze the cooling loads. Second, CFD is used for a more detailed airflow analysis on a typical floor plan of the model building. The results of the simulations on natural ventilation performance show that the Double-Skin Facade System can reduce the cooling load by 10.5% compared to the Double Sash Window.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.6 no.4
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• pp.249-254
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• 2013

In the area of computer vision, face recognition is being intensively researched. It is generally known that before a face is recognized it must be localized. Skin-color information is an important feature to segment skin-color regions. To extract skin-color regions the skin-color model based on multi-layer perceptron has been proposed. Extracted regions are analyzed to emphasize ellipsoidal regions. The results from this study show good accuracy for our vehicle driver face detection system.

• Journal of the Korean Society of Fashion and Beauty
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• v.2 no.2 s.2
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• pp.101-106
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• 2004

Allergic contact dermatitis is a common skin disease resulting from specific immunologic sensitization to topically applied various allergen. The Purpose of this study was to investigate skin morphologic cahnges by light microscopic and scanning electron Microscope, changes of protein band by SDS-PAGE(SDS-polyacrylamide gel electrophoresis) in the skin effectiveness for beruty improvement of Geranium essential oil on skin troubles by surfactant. The results of the study are as follows, 1. From the observed result of FE-Scanning Electron Microscope, groups treated by Geranium essential oil in group treated Geranium essential oil during 1 week in surfactant treated group during 1 week, the group was repaired in irregularity surface of tissue by alleviate-keratinization of Geranium essential oil. 2. As a result of protein analysis the group treated on surfactant was rised protein upper range of 97,0004a11on by hyper-keratinization and group treated during 1 week by surfactant was decreased protein below range of 43,000dalton.

• Annals of Clinical Neurophysiology
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• v.9 no.2
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• pp.43-50
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• 2007

Analysis of intraepidermal nerve fibers using skin biopsy is a recently developed technique, providing diagnostic information on small fiber neuropathies. The specimens are obtained by 3 mm punch biopsy, which is safe and minimally invasive. Immunohistochemical staining by Protein gene product (PGP) 9.5 demonstrate not only intraepidermal nerve fibers but dermal structures, such as sweat gland and erector papillae. Up to now, many studies agree that intraepidermal nerve fiber density is dramatically reduced in various sensory neuropathies. The utility of density measure was confirmed with high sensitivity in the diagnosis of sensory neuropathy, comparable to sural nerve biopsy or quantitative sensory testing. Besides quantitative methods, morphological changes like axonal swelling and fragmentation can be used as predegenerative markers. This article reviews the technique of skin biopsy and clinical and experimental usefulness of skin biopsy in diagnosing and monitoring peripheral neuropathies.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2007.11a
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• pp.153-158
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• 2007

Background: Naturally occurring antioxidants were used to regulate the skin damage caused by ultraviolet (UV) radiation because several antioxidants have demonstrated that they can inhibit wrinkle formation through prevention of matrix metalloproteinases (MMPs) and/or increase of collagen synthesis. We examined the effect of oral administration of the antioxidant mixture ("L-Skin Care") on UVB-induced wrinkle formation. In addition, we investigated the possible molecular mechanisms of photoprotection against UVB through inhibition of collagen-degrading MMP activity or through enhancing of pro collagen synthesis in mouse dorsal skin. Methods: Female SKH-l hairless mice were orally administrated "L-Skin Care" (test group) or vehicle (control group) for 10 weeks with UVB irradiation by three times a week. The intensity of irradiation was gradually increased from 30 to $180mJ/cm^2$. Microtopographic and histological assessments of the dorsal skins were carried out at the end of 10 weeks to evaluate wrinkle formation. Western blot analysis and EMSA were also carried out to investigate the changes in the balance of collagen synthesis and collagen degradation. Results: Our "L-Skin Care" significantly reduced UVB-induced wrinkle formation, accompanied by significant reduction of epidermal thickness, and UVB-induced hyperplasia, acanthosis and hyperkeratosis. Oral administration of "L-Skin Care" significantly prevented UVB-induced expressions of MMPs, mitogen-activated protein (MAP) kinases and activation of activator protein (AP)-1 transcriptional factor in addition to enhanced type I procollagen and transforming growth factor-$\beta$ (TGF-$\beta$) expression. Conclusion: Oral administration of "L-Skin Care" significantly inhibited wrinkle formation caused by chronic UVB irradiation through significant inhibition of UVB-induced MMP activity accompanied with enhancement of collagen synthesis.

• Biomolecules & Therapeutics
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• v.27 no.6
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• pp.553-561
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• 2019

Rab25, a member of the Rab11 small GTPase family, is central to achieving cellular polarity in epithelial tissues. Rab25 is highly expressed in epithelial cells of various tissues including breast, vagina, cervix, the gastrointestinal tract, and skin. Rab25 plays key roles in tumorigenesis, mainly by regulating epithelial differentiation and proliferation. However, its role in skin physiology is relatively unknown. In this study, we demonstrated that Rab25 knock-out (KO) mice show a skin barrier dysfunction with high trans-epidermal water loss and low cutaneous hydration. To examine this observation, we investigated the histology and epidermal differentiation markers of the skin in Rab25 KO mice. Rab25 KO increased cell proliferation at the basal layer of epidermis, whereas the supra-basal layer remained unaffected. Ceramide, which is a critical lipid component for skin barrier function, was not altered by Rab25 KO in its distribution or amount, as determined by immunohistochemistry. Notably, levels of epidermal differentiation markers, including loricrin, involucrin, and keratins (5, 14, 1, and 10) increased prominently in Rab25 KO mice. In line with this, depletion of Rab25 with single hairpin RNA increased the expression of differentiation markers in a human keratinocyte cell line, HaCaT. Transcriptomic analysis of the skin revealed increased expression of genes associated with skin development, epidermal development, and keratinocyte differentiation in Rab25 KO mice. Collectively, these results suggested that Rab25 is involved in the regulation of epidermal differentiation and proliferation.

• The Journal of Korean Medicine
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• v.40 no.2
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• pp.133-141
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• 2019

Objectives: The condition of the skin is greatly influenced by seasonal changes. We wanted to know the seasonal change of skin condition and to find out the difference in the efficacy of Seoshiokyongsan (SSOOS) CP soap in spring and autumn. We are to help people who use soap to make a wise choice in choosing a cleanser according to the season. Methods: To investigate the seasonal skin condition, this experiment was conducted to examine the skin condition of spring and autumn in 20 students at A university. To compare the seasonal efficacy of Seosiokyongsan (SSOOS) CP soap, we had skin test 10 students in spring and autumn. We made herbal fermented soaps using SSOOS and distributed them to experiment participants. We let them wash their face in the morning and evening for 6 weeks using herbal fermented soap. Prior to the experiment, their skin condition was checked and assessed using A-ONE Smart One-Click Automatic Facial Diagnosis System three times at 3-week intervals. After the experiment, the changes of skin were measured and analyzed through facial analysis test. Results: In spring and autumn, the oil of T zone and U zone was significantly less and the water content was significantly higher in autumn than in spring. In the case of using the SSOOS CP soap, water content increased and oil content decreased in spring, oil content and elasticity increased in autumn. Conclusion: There is a difference in the skin condition according to the season and SSOOS CP soap showed difference in efficacy in spring and autumn. So we should pay attention to seasonal soap selection.