• KSBB Journal
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• 제31권3호
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• pp.178-185
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• 2016

Aging of the face is mainly related to the features that are sagging or loss of elasticity of the skin by reducing the volume around the eyes or cheek. Intrinsic aging can be seen to cause thinner dermis, reduction of extracellular matrix and subcutaneous fat. This study was carried out to investigate the skin volume augmentation and anti-wrinkle effects of Tribulus terrestris fruit extract. Skin anti-aging effect of Tribulus terrestris fruit extract was evaluated by using lipid accumulation, expressin of type I procollagen and elastin in preadipocytes and human dermal fibroblasts. Tribulus terrestris fruit extract augmented preadipocytes differentiation about 56% at 100 µg/mL. The type I procollagen and elastin were increased about 35% and 25% by treatment 20% Tribulus terrestris fruit extract, respectively. The clinical study also showed that skin sagging, skin elasticity, and dermal density improved without adverse effect following 4 week application of cream containing 2% Tribulus terrestris fruit extract. We suggest that Tribulus terrestris fruit extract can have the good possibility as skin volume augmenting, skin elasticity and wrinkle improving agent.

• 한국임상수의학회지
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• 제20권2호
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• pp.198-206
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• 2003

The purpose of the present study was to investigate the effect of polyphosphate on healing of skin wound in rabbits. Four skin wounds of 8mm in diameter were induced bilaterally(4 wounds/rabbit) on the dorsolateral aspect of the trunk of 15 male New Zealand white rabbits. Ten percent polyphosphate(poly P) type 25, 10% poly P type 35, 10% poly P type 25+10% poly P type 35 and 0.85% sterile saline solution were applied on the wound area and examined grossly and histopathologically. The rate of wound contraction and histopathological changes after poly P application on the skin wound were investigated. In gross findings, the wound contraction rates of 10% poly P 25 group were significantly decreased from day 2 to day 7 after operation than those of 0.85% sterile saline solution treated group (p < 0.01). Although the hemorrhage and inflammation were observed on days 3, 6 and 9 after operation in all groups, but in 10% poly P 25 was gradually decreased. Revascularization and reepithelialization were seen 3, 6 and 9 days after operation in all groups, especially in 10% poly P 25 was formed completely on 9 days. Fibroplasia were seen 3. 6 and 9 days after operation in all groups, especially in 10% poly P 25 was compact than other groups on 9 days. The results suggested that polyphosphate, especially 10% poly P 25 would be effective on healing of skin wound in rabbits through decrease of would contraction rate, increase of revascularization, reepithelialization and fibroplasia.

• Journal of Ginseng Research
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• 제47권5호
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• pp.605-614
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• 2023

Ginsenosides are bioactive components of Panax ginseng with many functions such as anti-aging, anti-oxidation, anti-inflammatory, anti-fatigue, and anti-tumor. Ginsenosides are categorized into dammarane, oleanene, and ocotillol type tricyclic triterpenoids based on the aglycon structure. Based on the sugar moiety linked to C-3, C-20, and C-6, C-20, dammarane type was divided into protopanaxadiol (PPD) and protopanaxatriol (PPT). The effects of ginsenosides on skin disorders are noteworthy. They play antiaging roles by enhancing immune function, resisting melanin formation, inhibiting oxidation, and elevating the concentration of collagen and hyaluronic acid. Thus, ginsenosides have previously been widely used to resist skin diseases and aging. This review details the role of ginsenosides in the anti-skin aging process from mechanisms and experimental research.

• 약학회지
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• 제56권1호
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• pp.9-13
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• 2012

We previously reported that the extract of Taraxacum platycarpum (AF-343) had several biological properties such as skin hydration and anti-inflammatory effects, thereby AF-343 be a promising anti-atopic dermatitis agent. However, few studies have been conducted to evaluate its effect on modulation of extracellular matrix proteins in human skin fibroblasts. The purpose of this study was to investigate the expressions of type I collagen, MMP-1, Smad2/3, and TIMP-1 proteins in AF-343-treated human skin fibroblasts. Human skin fibroblasts were treated by various concentrations of AF-343 (0~2 mg/ml). The expressions of type I collagen, matrix metalloproteinase-1 (MMP-1), Smad2/3, and TIMP-1 proteins were analyzed by Western blot analysis. In addition, level of type I collagen mRNA was analyzed by CAT assay. Expression of type I collagen protein was increased in AF-343-treated human skin fibroblasts by dose and time-dependent manners. Consistent with this result, the expressions of phospho-Smad2/3 in skin fibroblasts were increased and MMP-1 expression was decreased by AF-343 treatment. TIMP-1 expression was not significantly changed in AF-343 treated skin fibroblasts. Extract of Taraxacum platycarpum (AF-343)-induced up-regulation of type I collagen expression was through increased expression of phospho-Smad2/3. These results were occurred combined with down-regulation of MMP-1 in skin fibroblasts. Taken together, this study indicated that AF-343 has property of the modulation of ECM in tissue as well as skin hydration and anti-inflammation.

• 대한화장품학회지
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• 제27권1호
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• pp.29-42
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• 2001

We had prepared MLV liposome with Hibiscus Esculentus Ext.(HEE) which have fluorescent light in order to evaluate its percutaneous absorption about hairless rat skin. Then we investigated particle size of MLV using confocal laser scanning microscope(CLSM) and transmission electron microscope(TEM), respectively. Stability of MLV liposome and penetration of MLV liposome to hairless rat skin was measured by CLSM. As a result of experiments, MLV was globular shape and the rage of particle size was 0.3-0.5$\mu\textrm{m}$ mostly. Cream-type MLV had high stability comparatively. When we treated with MLV to rat skin, skin penetration was enhanced, especially, the optimum concentration of MLV on penetration to rat skin was 10%. Optimum penetration time was 6hr-12hr. And MLV-type HEE was more effective on percutaneous absorption than HEE-cream or liposome-type HEE.

• 한국주거학회논문집
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• 제15권2호
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• pp.11-18
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• 2004

The purpose of this study is to evaluate the sound insulation performance and present fundamental data for sound insulation plan about open and close windows of inner facade and outer facade of Double-skin Facade system applied to multi-story type. The Headquarter of Green Building and the Energy Saving Building in the Korea Institute of Energy Research was selected for experiment. Measurement method which are specified in the Korea Standard 2235 were selected for this study. As the result of this study, 1) Sound insulation performance of Multi-layer type of Double-skin Facades is very excellent about outdoor noise. 2) Vertical level is higher, it shows that more decreases sound pressure level.

• The Korean Journal of Pain
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• 제7권1호
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• pp.49-52
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• 1994

Measurement of skin temperature is most frequently used to evaluate effect of sympathetic block. Sticker type skin temperature indicator, $ProChecker^{(R)}$, uses metamocolor, which changes the darkness of the color by giving and taking of electrons in response to temperature. We examined the accuracy of this skin temperature indicator in pain clinic patients who were treated with stellate ganglion block. Ten minutes before, and 10~20 minutes after stellate ganglion block, skin temperature on both dorsum of hand were measured using both $ProChecker^{(R)}$ and thermography concurrently. The results showed that skin temperature measured by $ProChecker^{(R)}$ was feasible, in correlation to thermography. Sticker type temperature indicator ($ProChecker^{(R)}$) is concluded as a useful monitor of skin temperature during nerve block in outpatient clinics.

• 패션비즈니스
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• 제24권6호
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• pp.120-134
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• 2020

Recently, the beauty industry has implemented personalized services based on skin big data. To increase competitiveness in the beauty industry, systematic data measurement and evaluation indicators are necessary to select data and obtain necessary knowledge. In response, this study sought to stably enhance the accuracy of skin diagnosis based on satisfaction and reliability. To this end, the research was conducted through focus group interviews (FGI), a case study of brands, and analysis of prior research results. In particular, as a result of analyzing keywords that classify skin types by brand, common survey items for skin types were oiliness and using moisturizer, cosmetic use and vascular of skin, external stimulus and blemish & freckles, facial wrinkle, outside activities, self-consciousness, and smoke. In additioin to the common questions of the preceding study and the brand survey items, the questions concerning complex skin types, seasonal change, facial color, wrinkles and elasticity were added, and the questions were presented in a total of 40 items. In particular, it suggested that skin measurement could be conducted by focusing on elasticity and pigmentation items by reflecting the results of prior research and the opinions of FGI, and based on this, a customized service with high satisfaction and high accuracy of beauty care based on this could be proposed. We hope that this study will facilitate active self-care by providing more satisfying skin stones and personalized cosmetics proposals, thus laying the foundation for the further development of the cosmetics industry.

• 한국의류학회지
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• 제22권1호
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• pp.116-126
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• 1998

This study was conducted to examine the effect of difference in materials of aerobic wear on both human body's physiological reactions and subjective wearing sensation by comparing and analysing not only cotton sparidex A, B and C but nylon spandex D, E and F used as actually wearing materials. The rectal temperature of type A and I remained at high degree, the type C was higher from after high-speed running but dropped sharply when taking a break finally. Both skin temperature and mean skin temperature dropped sharply due to sweat occurred during physical exercise, and then rose slowly when taking a break. Type A -D and B-I showed that the mean skin temperature remained at high degree when wearing a cotton spandex. Type C's temperature within its aerobic wear was lower than type F while its relative humidity was higher than type F. Wearing sensation showed a change similar to wearing, particularly, which was remarkable in type B-E. Also, it was shown that humidity sensation, tactile sensation and comfort sensation were good when wearing the cotton spandex.

• 한국의류학회지
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• 제24권8호
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• pp.1266-1275
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• 2000

This study was to research the actual condition of a dropworts working environment and to develope the clothing to reduce the work road. The actual conditions of working environment, working position and clothing were surveyed. Experiments were performed in the chamber and in the field. In the chamber, rectal temperature, 11 points skin temperatures(forehead, chest, abdomen, upperarm, forearm, dorsum manus, palm, thigh, calf, dorsum pedis and pelma), heart rates, microclimates inside clothing on the chest and subjective sensations were measured for comparing between 2 different types o garments. In the field, rectal temperature, abodomen skin temperature, 3 points microclimates inside clothing(chest, back and thigh), heart rates, the volume of EMG and subjective sensations were measured. The results were as follows; 1. There were no significant differences in rectal temperature between a old type protective clothing and a new type both in the chamber and the field. 2. Subjects wearing a old type clothing responded \"a little cold\", \"a little uncomfortable\" and subjects wearing a new type protective clothing responded \"normal\", \"comfortable\" both in the chamber and the field. 3. In the field test results, abodemen skin temperature in a old type clothing was higher and microtemperatures inside clothing of chest, back and thigh in a new type protective clothing were higher. 4. The volume of EMG was lower in the new type protective clothing than in the old one.protective clothing than in the old one.