• Biomolecules & Therapeutics
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• v.23 no.3
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• pp.238-244
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• 2015

Macrophage-derived chemokine, C-C motif chemokine 22 (MDC/CCL22), is one of the inflammatory chemokines that controls the movement of monocytes, monocyte-derived dendritic cells, and natural killer cells. Serum and skin MDC/CCL22 levels are elevated in atopic dermatitis, which suggests that the chemokines produced from keratinocytes are responsible for attracting inflammatory lymphocytes to the skin. A major signaling pathway in the interferon-${\gamma}$ (IFN-${\gamma}$)-stimulated inflammation response involves the signal transducers and activators of transcription 1 (STAT1). In the present study, we investigated the anti-inflammatory effect of dieckol and its possible action mechanisms in the category of skin inflammation including atopic dermatitis. Dieckol inhibited MDC/CCL22 production induced by IFN-${\gamma}$ (10 ng/mL) in a dose dependent manner. Dieckol (5 and $10{\mu}M$) suppressed the phosphorylation and the nuclear translocation of STAT1. These results suggest that dieckol exhibits anti-inflammatory effect via the down-regulation of STAT1 activation.

• Journal of Environmental Health Sciences
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• v.33 no.2 s.95
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• pp.83-91
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• 2007

This study investigated the health effects of offensive odor in residents living near the petrochemical industry complex area(PICA) and the thermoelectric power plant(TPP) by using questionnaire. Residents who felt the offensive odor were 58.3% at PICA, 50.9% at TPP and 24.4% at classical fishing and agrarian villages (CFAV)(p=0.000). People who answered that the offensive odor was sever at CFAV were 95.2% only on summer, but at PICA and TPP, were 44.1% and 57.3% on Spring, 62.4% and 68.8% on Summer, 22.0% and 31.7% on Autumn, and 21.7% and 25.7% on Winter, respectively. Average days that the odor occurred were 4.4 days/month at CFAV, but 12.0 and 9.5 days/month at PICA and TPP, respectively. People who experienced the sleep disturbance were 28.0% and 27.1% at PICA and TPP, respectively. The most frequently subjective symptoms were headache(0.953), frequently sneezing(0.825), itchy eyes(0.766), and stimulating eyes(0.709) at PICA, and headache(1.082), itchy eyes(0.931), itchy skin(0.826), and frequent sneezing(0.674) at TPP, respectively. At PICA and TPP, the occurrence rates of diseases in respondents' families were 15.4% and 15.6% for asthma, 12.4% and 9.2% for respiratory diseases, 27.8% and 31.2% for skin diseases, and 9.1% and 6.9% for nervous diseases, respectively. In conclusion, many residents who living near the PICA and TPP experienced the offensive odor during four seasons, especially high on summer, the most frequently subjective symptoms such as headache, itchy and stimulating eyes, frequently sneezing, and some diseases among their families such as asthma, respiratory diseases, skin diseases, and nervous diseases.

• Korean Journal of Human Ecology
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• v.7 no.1
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• pp.183-195
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• 1998

The purpose of this study is to investigate the effect of Ondol on the bedclimate, microclimate and physiological responses of occupants. Four healthy female subjects slept for seven hours in thermal environment of detached house and apartment respectively. Their bedclimate, microclimate, skin temperature, weight loss of body, weight of bedcloth and sleepwear, body movement and subjective sensation were measureed for this study. The results were as follows; The differences of bedclimate, microclimate, skin temperature were significant according to season and residence styles. The occupants of the detached house showed higher temperature and humidity inside quilt and clothes than those of the apartment did on apartment environment. The occupants of the detached house showed higher weight losses of body, heavier weights of quilt than those of the apartment did on apartment environment in the spring, autumn and winter, lower weight losses of mattress in the autumn and winter. The occupants of the detached house moved more than those of the apartment on apartment environment when sleeping. The occupants of the detached house felt higher thermal sensation and lower humidity sensation than those of the apartment did. The occupants of the detached house felt more comfortable than those of the apartment on detached house environment, while the occupants of the apartment felt more comfortable than those of the detached house on apartment environment. The thermal environments of the apartment and the detached house had an effect on the bedclimates, microclimates of occupants and therefore the physiological responses such as skin temperature, rectal temperature, weight loss of body, perspiration and subjective sensation are different during sleeping according to their residential styles on the same environment.

• The Research Journal of the Costume Culture
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• v.19 no.6
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• pp.1193-1204
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• 2011

As designs that simulate man's five wits are important, all five senses used are complex. Tactil value by Bernard Berenson means that the object in fine art makes the spectator feel like his or her finger is touching something, although the spectator is distant from the art piece. Especially as costumes have a relationship with the flexible skin and moving body, tactile modality and tactile value is more important. In order to analyze how Madeleine Vionnet realized a new femininity through the application of the principal of tactile value to dress design and in order to define tactile value in the field of fashion, this study examines the theory of tactile value, sculpture, painting, contemporary art, and product design as well as the design of Madeleine Vionnet from 1925 to 1937 because she was in the fashion business enlarging dress shops in New york during this period. The shape of Madeleine Vionnet's dresses made the concealed body alive through organic curves pressed against the body from cuts and dissections based on the anatomy of a supple body with curves and movement. In the garments, soft physical characteristics or the glossy touch of silk or pile textile imitated smooth skin while colors similar to a woman's eye, hair, and skin color continue the impression of the dress extending to the body through these design elements, Madeleine Vionnet's dresses reinforce the will to touch female body hidden under the dress by tactile values, not by the body's modification or visual exposure.

• Archives of Plastic Surgery
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• v.34 no.3
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• pp.383-387
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• 2007

Purpose: A necrotizing fasciitis is a rare, but insidiously advancing fatal soft tissue infection characterized by extensive fascial necrosis. Diagnosis & treatment of this disease are difficult. Necrotizing fasciitis tend to begin with constitutional symptoms of fever and chills. Quite a many lab studies and imaging studies such as standard radiography, computerized tomography can be used, but nothing can confine the extent of affected tissue. Aggressive surgical interventions are often required because of large skin and soft tissue deformity. However, many patients with necrotizing fasciitis are not healthy enough to overcome aggressive surgical intervention. Methods: Since 2000, we treated 10 patients with necrotizing fasciitis. In 4 patients, we used magnetic resonance imaging(MRI) as a tool for diagnosis as soon as necrotizing fascitiis was doubted. We treated patients with delayed coverage with Alloderm$^{(R)}$ & split thickness skin graft or delayed wound closure in as many cases as possible. Results: In 4 patients using preoperative MRI, diagnosis could be made in earlier stage of the disease compared to other patients. Our treatment modality was debridement and coverage with Alloderm$^{(R)}$ & split thickness skin graft. We could reconstruct deformities without significant limitation of movement in 7 cases. Conclusion: We diagnosed and treated 10 necrotizing fasciitis with MRI and Alloderm$^{(R)}$ graft, and results were good.

• Archives of Reconstructive Microsurgery
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• v.3 no.1
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• pp.64-71
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• 1994

The successful treatment of the extensively traumatized foot warrants reconstruction utilizing tissue that will provide adequate coverage, is resistant to infection, thin enough to conform to the contours of the foot as well as durable to constant frictional movement and weight bearing. Currently, free flaps offer the best means in achieving these difficult and sometimes contradictory goals. We treated twenty-one patients suffering from extensive soft tissue loss of the foot due to trauma, electric burn or postburn sequelae with free flaps. A fasciocutaneous, musculocutaneous or muscle flap with skin grafting was used based on the location, volume of tissue required, and the functional anatomical requirement of the injured region. The follow-up duration averaged twenty-nine months. From our group of patients, we believe that the muscle free flap with skin grafting offers the most favorable outcome.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.324-326
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• 2011

Measuring a biosignal during sleep is an important part of diagnosis and treatment of sleep disorder and also used to determine the general quality of sleep. As in current polysomnography, Contact method, which requires the attachment of electrodes to the skin, is the typical method to measure a biosignal during sleep. The procedure of this test is often considered to be inconvenient and tiresome because it requires attaching the device to the skin for each observation, and also limits free movement throughout the test. For this reason, the research on the acquiring the biosignal information without any attachment of a fixture on the skin is being conducted actively these days. In this study, it is suggested to check the heart rate per minute and the presence of breathing by placing a Piezo, which is a film type of pressure sensor, on the bed.

• Archives of Craniofacial Surgery
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• v.19 no.4
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• pp.254-259
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• 2018

Background: The esthetic and functional outcomes of periorbital defect reconstruction are very important because of the complex anatomy and specialized functions of this region. The orbicularis oculi myocutaneous (OOMC) flap is useful for the reconstruction of periorbital defects. But, according to the location and depth of the defects, the reconstruction using OMC flaps with various techniques is rare. The authors have used various kinds of OOMC flaps in various situations and we present an analysis of our experiences. Methods: From November 2001 to July 2017, we used 36 OOMC flaps to reconstruct 30 periorbital defects in 25 patients. We analyzed the cause of the defect, its location, the type of concomitant surgery, the method of flap movement, and complications. Results: Of the 30 defects, basal cell carcinoma was the most common cause, accounting for 20 cases. When the used OOMC flap was classified according to the location of the defects, the switch flap was used in nine cases among 15 defects of lower eyelid, and the V-Y advancement flap was mainly used for other parts. As surgical methods according to the depth of defect were classified, all cases involving the tarsal plate were reconstructed with a composite graft. In case of skin and muscles, they were reconstructed only with OOMC flap or with full-thickness skin graft. Conclusion: The OOMC flap provides good skin quality that is very similar to that of the defect tissue. Depending on the location and depth of the defect, the OOMC flap may be used properly in a variety of ways to achieve good results.

• Journal of the Korean Society of Clothing and Textiles
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• v.39 no.1
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• pp.63-76
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• 2015

This study conducted a survey to gauge the buying and wearing propensities of wearers of leg guards made for baseball catchers, as well as product characteristics of preferred leg guards. Data from the survey were analyzed to obtain basic data for the development of an advanced leg guard design. Degree of compression, horizontal distance, cross section view and outline 3D sketch were also analyzed from the 3D data of leg guards; in addition, mobility and kinematic analysis were conducted through a wearing test. The survey indicated that imported products dominate the current retail market because they are appreciated by customers in terms of fit, price, brand, and protection. Representative complaints of products were discomfort, pressure, and the heavy-weight of the leg guards in general attributed to overall structure and 3D shape. When the pressure was lower on the front area of knee, it feels better to wear and the average knee angular velocity during the up and down motion increased, which suggests a better design from a kinematic point of view. The knee is the primary part of the body responsible for any movement of the lower limbs; consequently, the degree of compression and support stability of the leg guards near the knee area are important factors to evaluate the performance of leg guards. The results of our study indicate significant opportunities for improvement in product design and the development of baseball leg guards along with an ergonomic design that considers the mobility of the knee, skin deformations is necessary to improve performance. The process followed in this study will be applicable to studies on other personal protective equipment for sports.

• The Research Journal of the Costume Culture
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• v.22 no.2
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• pp.290-299
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• 2014

This research sought to analyze the characteristics of breast movement at the treadmill activity levels. It also examined the effect of wearing a sports bra in reducing breast displacement. The subjects for the data collection were females in their 20s (n=2) with C-cup size breast. The experimental conditions were three different moving speeds (4 km/h, jogging: 7 km/h, and sprinting: 10 km/h) and two types of sports bras. Three dimensional breast displacement was measured. The displacement of the right nipple point was measured with a 3D motion analyzer. The results show that the breasts were greatly displaced from the walking speed (4 km/h) when subjects did not wear any bra. Whereas their breast displacement distance decreased remarkably when they wore sports bras. The nipple point moved 42~44 mm in the vertical direction at walking speed with naked condition. But it was reduced by 80% after wearing sports bras. When subjects running (7 km/h, 10 km/h) without any bra, the nipple point moved 122~141 mm. However it was reduced by 60~70% when they wore sports bras. The apartment time (time delay) between at the highest point of the upper body and the nipple was 0.25 seconds at the running speeds (7 km/h, 10 km/h) without wearing any bra. After wearing sports bras, the time delay was cut to 0.06~0.12 seconds. These results implies that without wearing any bra the skin surrounding the breasts might be seriously pulled at running activity. The functional sports bra suppress breast movement. It might prevent the sagging of breasts by preventing the damage of the Cooper's ligaments.