• Medical Lasers
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• v.8 no.1
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• pp.7-12
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• 2019

Background and Objectives Skin and soft tissue defects can be treated according to a range of strategies, such as local flap, skin graft, biological dressing, or free flap. On the other hand, free tissue transfer usually leaves a distinct scar with an inconsistency of color or hypertrophy. This problem is highlighted if the defect is located on the face, which could have devastating effects on a patient's psychosocial health. Materials and Methods The authors used an erbium : yttrium-aluminum-garnet (Er:YAG) laser to resurface the free flap skin and match the color with the surrounding facial skin. This study evaluated the effectiveness of laser skin resurfacing on the harmonious color matching of transferred flap. Patients who had undergone laser resurfacing on facial flap skin between January 2014 and December 2018 were reviewed retrospectively. An ablative 2,940-nm fractional Er:YAG laser treatment was delivered to the entire flap skin at 21 J/cm² with the treatment end-point of pinpoint bleeding. Several months later, the clinical photographs were analyzed. The L^*a^*b^* color co-ordinates of both the flap and surrounding normal skin were measured using Adobe Photoshop. The L^*a^*b^* color difference (ΔE) for the scar and normal surrounding skin were calculated using the following equation: ${\Delta}E=\sqrt{({\Delta}L)^2+({\Delta}a)^2+({\Delta}b)^2}$ Results All five patients were satisfied with the more natural appearance of the flaps. The ΔE values decreased significantly from the pre-treatment mean value of 19.64 to the post-treatment mean value of 11.39 (Wilcoxon signed-rank test, p = 0.043). Conclusion Ablative laser resurfacing can improve the aesthetic outcome of free tissue transfer on the face.

• Journal of Microbiology and Biotechnology
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• v.27 no.9
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• pp.1657-1663
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• 2017

Cosmetic patches have recently been developed as skin products for personal care owing to rapid advances in the technology of delivery of active ingredients, moisture, and adhesiveness to skin. Alginate and Spirulina are typical marine resources used in cosmetic products. This research involved the development of a Spirulina extract-impregnated alginate nanofiber cosmetic patch supported by a polycaprolactone (PCL) nanofiber cover (Spi/Alg-PCL NF patch). In addition to the ability of alginate to affect moisture and adhesiveness to skin, the impregnation of Spirulina extract strengthened those abilities as well as its own bioactive effectiveness. All fabrication processing steps were undertaken in aqueous solution. The three components (alginate, Spirulina extract, and PCL) had no detected cytotoxicity in human keratinocyte cell-based examination. In addition, wetting the pre-dried patch on the skin resulted in the Spirulina extract being released within 30 min. The results indicate the excellence of the Spi/Alg-PCL NF patch as a skin-care cosmetic device.

• The Journal of Pediatrics of Korean Medicine
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• v.35 no.3
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• pp.128-137
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• 2021

Objective The purpose of this study was to confirm the effectiveness of coptidis rhizoma extract-ceramide complex on skin barrier, transepidermal water loss (TEWL) and pH reduction, and inflammation of the skin. Methods Coptidis rhizoma extract-ceramide complex was applied in 6-week-old Balb/C mice after dermatitis was induced. To confirm the skin condition changes, TEWL and pH were observed, and filaggrin in the stratum corneum of the skin was observed. Kallikrein-related peptidase (KLK) 7, Protease activated receptor (PAR)-2, Thymic stromal lymphopoietin (TSLP), and IL-4 were observed in the stratum corneum to confirm the changes in the inflammatory response. Results Filaggrin positive reaction was increased in the experiment group compared to the control group. TEWL and pH were lower in the experiment group compared to the control group. KLK7, PAR2, TSLP, and IL-4 positive responses were decreased in the experiment group compared to the control group. Conclusions It was confirmed that the coptidis rhizoma extract-ceramide complex can relieve the inflammatory response of atopic dermatitis by restoring the skin lipid barrier damage.

• Journal of Korean Clinical Nursing Research
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• v.15 no.3
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• pp.49-59
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• 2009

Purpose: Examination was done of the effects on unplanned extubation, oral mucosa, and facial skin integrity in patients with oral intubation secured with a new method using Multifix Endo II. Methods: A prospective quasai-experimental design was used. Data were collected during a 3-week EICU admission period between Jun. 1 and Nov. 30. Two hundreds seventeen (conventional taping group: 105, Multifix Endo II group: 112) orally intubated adults were enrolled in the study at the EICU of the C University Hospital. Results: The incidence of unplanned extubation (${\chi}^2=11.580$, p=0.03) and scores for the facial skin integrity impairment of the Mutifix Endo II group (t=5.28, p=.000) were significantly lower than those of the conventional taping group even though the scores for oral mucosa impairment were not different. The nurse's evaluation of the clinical effectiveness of the two methods including convenience, comfort, safety, and satisfaction were also higher for the new securement method compared to the conventional taping group. Conclusion: The securement method using Mutifix Endo II was more effective than the conventional method in the prevention of unplanned extubation and maintenance facial skin integrity.

• Journal of information and communication convergence engineering
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• v.7 no.2
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• pp.131-134
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• 2009

The red-eye effect in photography occurs when using a photographic flash very close to the camera lens, in ambient low light due to in experience. Once occurred, the photographer needs to remove it with image tool that requires time consuming, skillful process. In this paper, we propose a new method to extract and remove such red-eye area automatically. Our method starts with transforming ROB space to YCbCr and HSI space and it extracts the face area by using skin color information. The target red-eye area is then extracted by applying 8-direction contour tracking algorithm and removed. The experiment shows our method's effectiveness.

• Journal of Korean Medicine for Obesity Research
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• v.7 no.1
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• pp.107-115
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• 2007

This report is to introduce a specific acupuncture methods as a cosmetic treatment. I applied wu-xing(五行) acupuncture technique to 11 patients for smooth out skin wrinkles. There were visual improvement of patients' facial skin. This methods cuts SMAS, stimulates dermis, and helps to recover skin volume and generate new dermal tissue by wound-healing mechanism.

• Biomolecules & Therapeutics
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• v.7 no.2
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• pp.191-197
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• 1999

The effects of various drugs on the alleviation of the symptoms of chemical bums were evaluated in mice to formulate topical antiblister preparations. After a chemical bum was induced on the mouse dorsal skin with 2-chloroethylethyl sulfide, the drug was applied on the disease site. The effectiveness of the drug was evaluated by determining blister size, necrosis score of skin and appearance of the chemical burns induced. It showed that steroids and aminoglycoside antibiotics had a tendency to protect skin cell, and antihistamines decreased the size of chemical bums. While oleaginous base resulted in deleterious effect, hydrophilic base didn't show a significant difference on the alleviation of the chemical burn symptoms compared to the control.

• Journal of the Korean Society of Industry Convergence
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• v.25 no.1
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• pp.101-110
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• 2022

For this purpose, the authors proposed and proved usefulness of the modified mean skin temperature which is integrated mean radiation temperature and the effect of floor contacted heat conduction. The mean radiation temperature is applied form factor between half cross-legged human body and surrounding wall of indoor. In addition the floor contacted heat conduction is applied heat transfer coefficient of half cross-legged human body. Eight Korean young men were targeted for the experiment. From the experiment the authors excerpted physiological reaction and psychological reaction in Ondol environment which is combined physiccal environmental factor of artificial climate chamber, air and floor temperature. As a result of the experiment it is confirmed that heat conduction has more impact than heat exchange from existing research for the heat exchange between half cross-legged human body and surrounding wall in Ondol thermal environment. Thereby, it is proved the effectiveness of the modified mean skin temperature which is added floor contacted temperature to the Ondol thermal environmental evaluation index.

• The Journal of the Korea Contents Association
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• v.15 no.1
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• pp.324-330
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• 2015

When diagnostic ultrasounds are used, an ultrasonic transmission media is used to effectively transmit the ultrasonic energy. Types of ingredients of polymer hydro gel, emulsion, and oil gel were compared with commercialized products by measuring characteristics of ultrasonic transmission media such as skin lubricity, skin moisturizing, and dryness speed which were contained in each different media. The mean friction coefficient measured to investigate skin lubricity showed high in the agent containing a large amount of oil, whereas the mean friction coefficient of the low viscosity emulsion did not show a significant difference with that of the polymer hydro gel. The moisture evaporation measured to investigate the dryness speed of the agent showed highest in polymer hydro gel. This showed that the larger amount of oil it had, the less moisture evaporation occurred. For skin moisture measured to investigate moisturizing characteristics of skin, low viscosity emulsion showed high in moisture content, whereas it showed slowest reduction in moisture content. As a type of emulsion appropriately containing water and oil is superior in skin moisturizing and skin tenderness, it is expected to serve as a dosage form of new ultrasonic transmission media.

• Journal of the Korean Society of Fashion and Beauty
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• v.3 no.2 s.2
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• pp.12-17
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• 2005

Efficiency study of chamomile and Thyme essential oil about the basal layer & sebaceous gland in dry-skin induced by surfactant is as following : 1. Formal observation of outer skin layer and basal layer There was refreshing effects about Surfactant induction skin inflammation in Chamomile, Thyme essential oil processing group but effect in surface layer appeared by higher thing in Chamomile essential oil and it could know that thing which do not use Thyme essential oil in case Thyme essential oil is ultraviolet rays allergy at skin care because Melanocyte appear on the surface is bigger than Chamomile essential oil that it was usefully reaction in basal layer. 2. Formal observation result of sebaceous glands. There are few damages in all group but there is recuperative through excessive water damage by excessive a sebaceous gland made of mulberry bark secretion because Thyme essential oil application group cause chapped skin phenomenon after surface-active agent processing but is seen that difference does not exist greatly and Thyme essential oil that general skin is strong in permeation is effective, but Surfactant induction skin inflammation estimates that Chamomile essential oil is effective. Therefore, it was considered that use of Chamomile essential oil is effectiveness than Thyme essential oil by essential oil used for recovery after damage of inflammation etc..