• 한국한의학연구원논문집
• /
• 제14권3호
• /
• pp.103-111
• /
• 2008

Recently, skin diagnosis has been suggested as a promising tool for discrimination of Sasang Constitution, reported by examining the skin characteristics such as thickness, stiffness, slip, and skin textures like wrinkles and furrows. However, the works had a limitation in that clinical decision on the skin characteristics was made by relying upon oriental medicine doctors' subjective sense of touch. In order to objectify the skin diagnosis and claim its efficacy on the discrimination of the Sasang Constitutions, it is necessary to demonstrate its discrimination capability by providing numerical values in terms of physical quantities obtained from measurements using today's sensors and equipment technologies, which motivated this work as a priliminary step towards objectification of skin diagnosis. The skin characteristics focused in this work is the slip property of the back-hand skin that has been exploited using the dynamic friction measurement system. First, curved geometric effects of the back-hand skin on the measured lateral/vertical force signals were estimated using the artificially designed silicon coated structures, which led to a suggestion on a quality controlled experimental design based upon a empirical analysis model. Second, the experimental design thus suggested has been applied to the measurement of dynamic friction coefficients for two healthy male subjects of Taeumin (TE) and Soyangin (SY), respectively. The result shows that the dynamic friction coefficient is less for the SY subject than for the TE subject around the area of the skin used for diagnosis by the oriental medicine doctor, implying the TE subject's skin is more slippery than the SE subject's that is consistent with the oriental medicine doctor's diagnosis. Hopefully, this work can provide guidelines for obtaining quality data in friction measurement to be collected for discussion on the efficacy of the skin diagnosis and its objectification through statistical analysis.

• 한국멀티미디어학회논문지
• /
• 제25권8호
• /
• pp.1212-1223
• /
• 2022

Skin lesions are common diseases that range from skin rashes to skin cancer, which can lead to death. Note that early diagnosis of skin diseases can be important because early diagnosis of skin diseases considerably can reduce the course of treatment and the harmful effect of the disease. Recently, the development of computer-aided diagnosis (CAD) systems based on artificial intelligence has been actively made for the early diagnosis of skin diseases. In a typical CAD system, the accurate classification of skin lesion types is of great importance for improving the diagnosis performance. Motivated by this, we propose a novel deep ensemble classification with multi-scale attention networks. The proposed deep ensemble networks are jointly trained using a single loss function in an end-to-end manner. In addition, the proposed deep ensemble network is equipped with a multi-scale attention mechanism and segmentation information of the original skin input image, which improves the classification performance. To demonstrate our method, the publicly available human skin disease dataset (HAM 10000) and the private animal skin lesion dataset were used for the evaluation. Experiment results showed that the proposed methods can achieve 97.8% and 81% accuracy on each HAM10000 and animal skin lesion dataset. This research work would be useful for developing a more reliable CAD system which helps doctors early diagnose skin diseases.

• 한국컴퓨터정보학회논문지
• /
• 제27권3호
• /
• pp.137-147
• /
• 2022

피부상태의 진단과 관리는 뷰티산업종사자와 화장품산업종사자에게 그 역할을 수행함에 있어서 매우 기초적이며 중요한 기능이다. 정확한 피부상태 진단과 관리를 위해서는 고객의 피부상태와 요구사항을 잘 파악하는 것이 필요하다. 본 논문에서는 피부상태 진단 및 관리를 위해 소셜미디어의 빅데이터를 사용하여 피부상태 진단 및 관리를 지원하는 빅데이터기반 피부관리정보시스템 SCIS를 개발하였다. 개발된 시스템을 사용하여 텍스트 정보 중심의 피부상태 진단과 관리를 위한 핵심 정보를 분석하고 추출할 수 있다. 본 논문에서 개발된 피부관리정보시스템 SCIS는 빅데이터 수집단계, 텍스트전처리단계, 이미지전처리단계, 텍스트단어분석단계로 구성되어 있다. SCIS는 피부진단 및 관리에 필요한 빅데이터를 수집하고, 텍스트 정보를 대상으로 핵심단어의 단순빈도분석, 상대빈도분석, 동시출현분석, 상관성분석을 통해 핵심단어 및 주제를 추출하였다. 또한 추출된 핵심단어 및 정보를 분석하고 산포도, NetworkX, t-SNE 및 클러스터링 등의 다양한 시각화 처리를 함으로써 피부상태 진단 및 관리에 있어 이를 효율적으로 사용할 수 있도록 하였다.

• 대한의사협회지
• /
• 제61권11호
• /
• pp.649-654
• /
• 2018

Although the dermoscopy had very long history since its introduction in 17th century, only recently it has been possible to see the widespread application of dermoscopy in the dermatology clinic. One of the most promising areas where the dermoscopy can be applied is the diagnosis of skin cancer, especially malignant melanoma. Due to its inherent limitation to obtain in-depth information-literally, from more than skin-deep and more importantly, from microscopic structures-of skin cancers, dermoscopy cannot replace the present gold-standard 'biopsy' in the diagnosis of skin cancer. However, several advantages of dermoscopy over biopsy merit further considerations. For example, as a non-invasive tool, dermoscopy is best suited for the follow-up of suspicious skin lesions, and as an all-at-a-glance tool, dermoscopy can aid the selection of the best biopsy-site to obtain the most meaningful pathological information from the minimal tissue specimen. There goes a saying that 'it takes two to tango,' similarly, we might need the two (biopsy and dermoscopy) to cope rhythmically with the varying tempos of everprogressing skin tumorigenesis and to reveal the true face of skin cancers usually hidden in various disguises.

• 대한두경부종양학회지
• /
• 제21권2호
• /
• pp.174-177
• /
• 2005

Skin metastasis from papillary thyroid carcinoma is extremely rare. Due to similar histopathologic features, it is difficult to differentiate skin metastatic papillary thyroid carcinoma and some primary skin neoplasms without a clinical history. However, most of metastatic skin lesions showed a strong reactivity to the antithyroglobulin antibodies unlike primary skin neoplasms. Metastatic skin lesions must be completely removed and radiotherapy can be added. Investigators reported that prognosis of skin metastases from thyroid carcinoma is dismal and the average survival after it's diagnosis was only 19 months because distant metastases were often discovered at diagnosis of skin metastasis or during follow-up period. We report a case of skin metastasis from tall cell variant of papillary thyroid carcinoma. In our case, the anti thyroglobulin antibodies measured from cystic fluid from a skin lesion was more than 2000 IU/ml. Skin metastasis was diagnosed at 20 months after primary surgery for thyroid cancer and brain metastasis at 12 months after diagnosis of skin metastasis. Although skin metastasis is an ominous prognostic indicator in patients with thyroid carcinoma, a radical treatment for skin lesions and early diagnosis of distant metastasis could provide a chance to the patients to improve their survival.

• 한국컴퓨터정보학회논문지
• /
• 제27권8호
• /
• pp.241-251
• /
• 2022

화장품 및 뷰티산업에서 고객의 피부상태 진단과 관리는 중요한 필수기능이다. 소셜미디어 환경이 사회 전 분야에 확산되고 일반화되면서 피부 상태의 진단과 관리에 대한 다양하고 섬세한 고민과 요구 사항의 질문과 답변의 상호작용이 소셜미디어 커뮤니티에서 활발하게 다루어지고 있다. 그러나 소셜미디어 정보는 매우 다양하고 비정형적인 방대한 빅데이터이므로 적절한 피부상태 정보분석과 인공지능 기술을 접목한 지능화된 피부상태 진단 시스템이 필요하다. 본 논문에서는 소셜미디어의 텍스트 분석정보를 학습데이터로 가공하여 고객의 피부상태를 지능적으로 진단 및 관리하기 위한 피부상태진단시스템 SCDIS를 개발하였다. SCDIS에서는 딥러닝 기계학습 방법인 인공신경망 기술을 사용하여 자동적으로 피부상태 유형을 진단하는 인공신경망 모델 AnnTFIDF을 빌드업하여 사용하였다. 인공신경망 모델 AnnTFIDF의 성능은 테스트샘플 데이터를 사용하여 분석되었으며, 피부상태 유형 진단 예측 값의 정확성은 약 95%의 높은 성능을 나타내었다. 본 논문의 실험 및 성능분석결과를 통하여 SCDIS는 화장품 및 뷰티산업 분야의 피부상태 분석 및 진단 관리 과정에서 효율적으로 사용 가능한 지능화된 도구로 평가할 수 있다. 본 논문에서 제안된 시스템은 소셜미디어 기반의 새로운 환경에서 화장품 및 피부미용에 대한 사용자의 요구를 체계적으로 파악하고 진단하는 기초 기술로 사용 가능할 것이다. 그리고 이 연구는 새로운 기술 트렌드인 맞춤형 화장품제조와 소비자중심의 뷰티산업기술 수요를 해결하기 위한 기초 연구로 사용될 수 있을 것이다.

• 사상체질의학회지
• /
• 제19권3호
• /
• pp.126-143
• /
• 2007

1. Objectives The purpose of this study is to find out the grade of practical use, the important element and the significant characteristics of Sasangin' s face, voice, skin and pulse diagnostic impression, in Sasang constitutional clinical diagnosis. 2. Methods We analysed the survey data about Sasangin' s face, voice, skin and pulse diagnostic impression, drawn up by specialist in Sasang constitutional medicine. 3. Results and Conclusions (1) In the application degree of face feature, the case which it was applied with 20-40% and 40-60% were 16 people(43.2%) respectively. In voice, the case applied with 0-20% was 19 people(51.4%), in skin, 0-20% and 20-40% were 14 people(37.8%) respectively and in pulse diagnosis, 0-20% were 25 people(73.0%). (2) In constitutional diagnosis, the important element of face were 'frontal whole shape', 'whole impression' and 'size and shape of eye, ear, mose and mouth', the important element of voice 'speed of speech', 'purity and impurity' and 'pitch', the important element of skin 'thickness', 'feel of touch' and 'size of skin pores' and the important element of pulse diagnosis 'speed of pulse', 'sinking and floating' and 'weakness and firmness'. (3) The important face characteristics of Taeyangin were 'bright eye', 'broad forehead' and 'strong impression', Soyangin 'protruding forehead', 'thin and small lips', 'narrowing and sharp chin', Taeumin 'thick lips', 'flat face', 'large eye, nose, ear and mouth' and Soeumin 'long and slender face', 'downward slanting eyes' and 'small eye, nose, ear and mouth', The important voice characteristics of Taeyangin were 'loud' and 'clear', Soyangin 'rapid' and 'high-pitched tone', Taeumin 'chick', 'slow' and 'low-pitched tone' and Soeumin 'small and feeble' and 'slow'. The important skin characteristics of Taeyangin were 'thin' and 'white', Soyangin 'thin', 'smooth' and 'elastic', Taeumin 'thick', 'large skin-pore', 'coarse' and Soeumin 'soft', 'thin' and 'subtle skin-pore'. The important pulse characteristics of Taeyangin were 'rapid' and 'large', Soyangin 'rapid' and 'floating', Taeumin 'tense', 'long' and 'solid' and Soeumin 'fine', 'weak' and 'slow'.

• 대한두개안면성형외과학회지
• /
• 제21권2호
• /
• pp.87-91
• /
• 2020

Background: The incidence of skin cancer, which is primarily caused by exposure to ultraviolet radiation, has steadily increased in recent years. The authors of the present study sought to investigate changes in the epidemiology of skin cancer by conducting a retrospective review of patients diagnosed with skin cancer who received related care at a single medical institution. Methods: The present study included patients who were diagnosed with skin cancer and received treatment at Gyeongsang National University Hospital from 2008 to 2018. The site and type of skin cancer, the number of patients with skin cancer each year, the sex and sex ratio of the patients, and changes in patients' age at first diagnosis were examined through retrospective chart reviews. Results: The number of patients with skin cancer significantly increased, but statistically significant changes were not found in patients' sex, skin cancer sites, or the types of skin cancer. However, patients' age at the first diagnosis of skin cancer showed a statistically significant decrease starting in 2015. Conclusion: In this study, the number of patients with skin cancer increased over time. However, patients' age at first diagnosis has decreased since 2015. Therefore, younger patients should take care to prevent skin cancer, and further research on the causes of skin cancer in younger patients is needed.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권8호
• /
• pp.3403-3406
• /
• 2015

Background: Skin biopsy is the method to assist clinicians to make definite dermatological diagnosis which further helps in holistic management. Skin cancers are relatively rare clinical diagnosis in developing countries like Nepal, but the prevalence is on rise. Objectives: To investigate the profile of skin biopsies and frequencies and pattern of skin cancers in a tertiary care centre of Western Nepal. Materials and Methods: The materials consisted of 434 biopsies (1.37%) out of 31,450 OPD visits performed in the Department of Dermatology, Manipal Teaching Hospital, Pokhara, Nepal, during the period of Dec 2011-Nov 2014. Data were collected and analyzed using SPSS-16 with reference to incidence, age, sex, race and clinical and histopathological features. Results: The commonest disorders observed in biopsies were papulosquamous lesions, skin tuberculosis of different types, benign skin tumors, leprosy, collagen and fungal diseases. Viral diseases were rarely seen, probably due to straight forward clinical diagnosis. Dermatological malignancies accounted for 55/434 (12.67%) of biopsies. Skin disorders in general were commoner in females 280/434 (64%), including malignancies 32/55(58.2%). Mean age of patients with skin cancer was 54.5 years. Facilities for proper laboratory investigation of dermatological disorders will improve the quality of life. Conclusions: The most prevalent lesion in skin biopsies was papulosquamous disorders followed by skin tuberculosis of different types. Dermatological malignancy constituted 55/434 (12.67%) cases. The prevalence of skin malignancy is on rise in Nepalese society probably due to increase in life expectancy and better diagnostic services.

• 사상체질의학회지
• /
• 제22권4호
• /
• pp.20-29
• /
• 2010

1. Objectives Our goal is to observe the feasibility of constitution discrimination from computing quantitative roughness index from dynamic friction coefficients and their gradients with the measurement device of skin friction with 3-Axis load cell sensor. 2. Methods In the traditional Korean medicine, skin diagnosis is one of the examination methods to discriminate Sasang constitution since it was known that Tae-eumin has rough skin, and Soyangin has smooth one. It is based on the skin roughness on the back of one's hand for the discrimination. The measurement device of skin friction with 3-axis load cell sensor has been developed in order to provide quantitative skin roughness through dynamic friction coefficients. The effective interval of the coefficients is obtained from the automatic sampling algorithm to use their curvature and slope. Then, Fisher's discriminant function of them makes the discrimination. 3. Results The success rate of extracting the effective interval was about 90% and the discriminant accuracy between Tae-eumin and Soyangin was 70% and 68% for men and women, respectively. The entire methods showed the possibility to distinguish between Tae-eumin and Soyangin by using stochastic properties of roughness index, which can make the entire system to include the measurement, the computation of the roughness index and the discrimination of constitution automatical. 4. Conclusions The measurement device, the automatic sampling algorithm of dynamic friction coefficients and the constitution discrimination algorithm were developed, respectively, and their combination can become the serial and automatic procedure for quantitative and objective skin diagnosis, which mimics the movement of the Oriental medical doctors' skin diagnosis. It can be applied to healthcare as well as the diagnosis of constitution in a u-Health system soon.