• Title/Summary/Keyword: Skewness factor

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Hepatocellular Carcinoma: Texture Analysis of Preoperative Computed Tomography Images Can Provide Markers of Tumor Grade and Disease-Free Survival

  • Jiseon Oh;Jeong Min Lee;Junghoan Park;Ijin Joo;Jeong Hee Yoon;Dong Ho Lee;Balaji Ganeshan;Joon Koo Han
    • Korean Journal of Radiology
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    • v.20 no.4
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    • pp.569-579
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    • 2019
  • Objective: To investigate the usefulness of computed tomography (CT) texture analysis (CTTA) in estimating histologic tumor grade and in predicting disease-free survival (DFS) after surgical resection in patients with hepatocellular carcinoma (HCC). Materials and Methods: Eighty-one patients with a single HCC who had undergone quadriphasic liver CT followed by surgical resection were enrolled. Texture analysis of tumors on preoperative CT images was performed using commercially available software. The mean, mean of positive pixels (MPP), entropy, kurtosis, skewness, and standard deviation (SD) of the pixel distribution histogram were derived with and without filtration. The texture features were then compared between groups classified according to histologic grade. Kaplan-Meier and Cox proportional hazards analyses were performed to determine the relationship between texture features and DFS. Results: SD and MPP quantified from fine to coarse textures on arterial-phase CT images showed significant positive associations with the histologic grade of HCC (p < 0.05). Kaplan-Meier analysis identified most CT texture features across the different filters from fine to coarse texture scales as significant univariate markers of DFS. Cox proportional hazards analysis identified skewness on arterial-phase images (fine texture scale, spatial scaling factor [SSF] 2.0, p < 0.001; medium texture scale, SSF 3.0, p < 0.001), tumor size (p = 0.001), microscopic vascular invasion (p = 0.034), rim arterial enhancement (p = 0.024), and peritumoral parenchymal enhancement (p = 0.010) as independent predictors of DFS. Conclusion: CTTA was demonstrated to provide texture features significantly correlated with higher tumor grade as well as predictive markers of DFS after surgical resection of HCCs in addition to other valuable imaging and clinico-pathologic parameters.

A Study on Class-based Turnover Assignment in Automated Storage/Retrieval Systems with Continuous Rectangular Rack Face in Time

  • Hwang, Hark;Koh, Sie-Gheun;Jang, Gil-Sang
    • Journal of Korean Institute of Industrial Engineers
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    • v.14 no.1
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    • pp.31-42
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    • 1988
  • This paper studies class-based turnover assignment rule in terms of the expected travel time in automated storage/retrieval systems (AS/RS). With the rack face not necessarily in square in time, travel time models of two and three-class systems are developed, from which class partition values are determined for single command cycle. Also, the effects of the system parameters such as the rack shape factor and the skewness of the ABC curve are evaluated on the travel time through example problems.

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Optimal Selection of Master States for Order Reduction (동적시스템의 차수 줄임을 위한 주상태의 최적선택)

  • 오동호;박영진
    • Journal of KSNVE
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    • v.4 no.1
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    • pp.71-82
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    • 1994
  • We propose a systematic method to select the master states, which are retained in the reduced model after the order reduction process. The proposed method is based on the fact that the range space of right eigenvector matrix is spanned by orthogonal base vectors, and tries to keep the orthogonality of the submatrix of the base vector matrix as much as possible during the reduction process. To quentify the skewness of that submatrix, we define "Absolute Singularity Factor(ASF)" based on its singular values. While the degree of observability is concerned with estimation error of state vector and up to n'th order derivatives, ASF is related only to the minimum state estimation error. We can use ASF to evaluate the estimation performance of specific partial measurements compared with the best case in which all the state variables are identified based on the full measurements. A heuristic procedure to find suboptimal master states with reduced computational burden is also proposed. proposed.

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REYNOLDS NUMBER EFFECTS ON TURBULENT PIPE FLOW PART II. INSTANTANEOUS FLOW FIELD,HIGHER-ORDER STATISTICS AND TURBULENT BUDGETS (난류 파이프 유동에서의 레이놀즈 수 영향: Part II. 순간유동장, 고차 난류통계치 및 난류수지)

  • Kang, Chang-Woo;Yang, Kyung-Soo
    • Journal of computational fluids engineering
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    • v.16 no.4
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    • pp.100-109
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    • 2011
  • Large eddy simulation(LES) of fully developed turbulent pipe flow has been performed to investigate the effect of Reynolds number on the flow field at $Re_{\tau}$=180, 395, 590 based on friction velocity and pipe radius. A dynamic subgrid-scale model for the turbulent subgrid-scale stresses was employed to close the governing equations. The mean flow properties, mean velocity profiles and turbulent intensities obtained from the present LES are in good agreement with the previous numerical and experimental results currently available. The Reynolds number effects were observed in the higher-order statistics(Skewness and Flatness factor). Furthermore, the budgets of the Reynolds stresses and turbulent kinetic energy were computed and analyzed to elucidate the effect of Reynolds number on the turbulent structures.

A Statistical Approach to Analysis of Saccadic Eye Movements (Saccadic 안구운동 해석에 대한 통계학적인 접근)

  • Kim, Nam-Gyun;Kim, Bu-Gil
    • Journal of Biomedical Engineering Research
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    • v.10 no.3
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    • pp.289-292
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    • 1989
  • In this study we propose an approach based on statistical method which use the whole of saccades instead of using a few points of saccades in the quantitative analyse saccades. We computed statistical parameters such as mean velocity, quadratic mean velocity, standard duration, skewness of saccades velocity, flattness factor of saccades velocity, and mean delay by considering eye velocity as a probability density function. The results abtained are the following as ; This parameters showed the same trend like that of the main sequence. They were not biased by the systematic errors due to the arbitrary threshold. They were also less sensitive to noise, which was tested through the model simulation. So they are expected to provide a more comprehensive quantitative description of the dynamic properties of saccade in the diagnostic field.

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Levy-Type Swaption Pricing Model (Levy-Swaption 가치 평가 모형)

  • Lee, Joon-Hee;Park, Jong-Woo
    • Korean Management Science Review
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    • v.25 no.3
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    • pp.1-12
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    • 2008
  • The Swaption is one of the popular Interest rates derivatives. In spite of such a popularity, the swaption pricing formula is hard to derived within the theoretical consistency. Most of swaption pricing model are heavily depending on the simulation technique. We present a new class of swaption model based on the multi-factor HJM levy-mixture model. A key contribution of this paper is to provide a generalized swaption pricing formula encompassing many market stylize facts. We provide an approximated closed form solution of the swaption price using the Gram-Charlier expansion. Specifically, the solution form is similar to the market models, since our approximation is based on the Lognormal distribution. It can be directly compared with the traditional Black's formula when the size of third and fourth moments are not so large. The proposed extended levy model is also expected to be capable of producing the volatility smiles and skewness.

Fault Detection of the Machine Tool Gearbox using Acoustic Emission Methodof (음향 방출법에 의한 공작기계 기어상자의 결함 검출)

  • Kim, Jong-Hyeon;Kim, Won-Il
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.11 no.4
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    • pp.154-159
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    • 2012
  • Condition monitoring(CM) is a method based on Non-destructive test(NDT). Therefore, recently many kind of NDT were applied for CM. Acoustic emission(AE) is widely used for the early detection of faults in rotating machinery in these days also. Because its sensitivity is higher than normal accelerometers and it can detect low energy vibration signals. A machine tool consist of many parts such as the bearings, gears, process tools, shaft, hydro-system, and so on. Condition of Every part is connected with product quality finally. To increase the quality of products, condition monitoring of the components of machine tool is done completely. Therefore, in this paper, acoustic emission method is used to detect a machine fault seeded in a gearbox. The AE signals is saved, and power spectrums and feature values, peak value, mean value, RMS, skewness, kurtosis and shape factor, were determined through Matlab.

A Stochastic Analysis in Steam Turbine Blade Steel Using Monte Carlo Simulation (몬테카를로 시뮬레이션을 이용한 증기 터빈블레이드재의 확률론적 해석)

  • Kim, Chul-Su;Jung, Hwa-Young;Kang, Myung-Su;Kim, Jung-Kyu
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.26 no.11
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    • pp.2421-2428
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    • 2002
  • In this study, the failure probability of the degraded LP turbine blade steel was performed using the Monte Carlo simulation to apply variation of applied stress and strength. For this purpose, applied stress under the service condition of steady state was obtained by theoretical stress analysis and the maximum Von-Mises stress was 219MPa. The fatigue strength under rotating-bending load was evaluated by the staircase method. Furthermore, 3-parameter Weibull distribution was found to be most appropriate among assumed distributions when the probabilistic distributions of tensile and fatigue strength were determined by the proposed analysis. The failure probability with various loading conditions was derived from the strength-stress interference model and the characteristic factor of safety was also estimated.

An Experimental Study About The Intermittent Flow Field in The Transition Region of a Turbulent Round Jet (발달하는 원형제트의 간헐적 유동에 관한 실험적 연구)

  • 김숭기;조지룡;정명균
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.14 no.1
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    • pp.230-240
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    • 1990
  • An exprimental research has been carried out to find the intermittent flow pattern in the transition region of a turbulent round jet in order to elucidate detailed turbulence structure and to accumulate basic data necessary for computational turbulence modelling. Turbulent signals were processed digitally to obtain conventional or conditional velocity components. The high-order conditional correlations obtained in this study showed similar trends as those of other free shear flows. It was found that the non-turbulent fluid contributes negligibly to the turbulent kinetic energy production and its diffusive transport and that the diffusion by bulk convection has the same order of magnitude as the gradient diffusion in the free boundary region. The statistical analyses such as flatness factor, skewness factor and probability density functions of turbulent and non-turbulent zone durations have also been performed.

A Study on the Turbulent Flow Characteristics of Swirl Jets for Improvement of Combustion Efficiency (연소효율 개선을 위한 스월제트의 난류유동 특성에 관한 연구)

  • Ko, Dong Guk;Yoon, Suck Ju
    • Journal of ILASS-Korea
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    • v.19 no.2
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    • pp.75-81
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    • 2014
  • Swirl flow in the gun type burner has a decisive effect on the stabilization of the flame, improvement of the combustion efficiency, and also a reduction of NOx. This swirl flow is created by the spinner which is inside the airtube that guide the combustion air. Gun type burner has generally the inner devices composed nozzle adapter, spark gap ignitor, and spinner. These inner components change the air flow behavior passing through air tube. Meanwhile, turbulent characteristics of this air flow are important to understand the combustion phenomena in the gun type burner, because the mixture of fuel and air are depended on. However, nearly all of the studies have been analyzed the turbulent flow of simplified combustion formation without the inner devices. So, this study conducted the measurement using by hot-wire anemometer and analyzed turbulent flow characteristics of the swirl flow discharged from the air tube with inner devices. Turbulence characteristics come up in this study were turbulence intensity, kinetic energy and shear stress of the air flow with the change of the distance of axial direction from the exit of the air tube.