• 대한치과교정학회지
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• 제20권1호
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• pp.111-122
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• 1990

To investigate the relationship of skeletal maturity among the normal occlusion group and each malocclusion groups, the author used hand and wrist X-ray of 133 Korean 13 year old boys (normal occlusion 30, Class I malocclusion 35, Class II malocclusion 35 and Class III malocclusion 33) and assessed their skeletal maturity. In this study, fourteen skeletal maturity stages were selected from; Radius, Hamate, Pisiform, Ulnar sesamoid of the metacarpophalangeal joint of the first thumb, proximal phalanges of the first, second and third finger, middle and distal phalanx of the third finger. The difference of skeletal maturity of each malocclusion groups in relative to normal occlusion group and that of each malocclusion groups were analyzed. The findings of this study can be summerized as follows: 1. Average skeletal maturity stage of each groups were MP3cap stage in normal occlusion group, H-2 stage in Class I malocclusion group, midstage between S and H-2 stage in Class II malocclusion group, MP3cap stage in Class III malocclusion group. 2. There was no significant difference in skeletal maturity of Class I malocclusion and Class III malocclusion groups in relative to normal occlusion group. 3. There was significant retardation of skeletal maturity in Class II malocclusion group in relative to normal occlusion group. 4. There was no significant difference in skeletal maturity between Class I and Class II malocclusion groups. 5. There was no significant difference in skeletal maturity between Class I and Class III malocclusion groups. 6. There was significant retardation of skeletal maturity in Class II malocclusion group in relative to Class III malocclusion group.

• Annals of Occupational and Environmental Medicine
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• 제35권
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• pp.40.1-40.10
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• 2023

Background: Efforts for the prevention and management of cardiovascular diseases (CVDs) in workers have been actively pursued. Obesity is one of the important risk factors related to CVDs. Obesity has various metabolic characteristics, and some individuals can be metabolically healthy. Body composition including skeletal muscle mass is known to have protective effect in obesity. The study aims to investigate the association between skeletal muscle mass and Korea Occupational Safety and Health Agency (KOSHA) CVD risk among obese male manufacturing workers in Korea and to identify appropriate indicators of skeletal muscle mass for predicting risk of CVDs. Methods: The study was conducted on 2,007 obese male workers at a manufacturing industry aged more than 19 years. Skeletal muscle mass, skeletal muscle index (SMI), skeletal muscle mass percent (SMM%) and skeletal muscle to body fat ratio (MFR) were used to evaluate body composition and these indicators were divided into quartiles. The odds ratios (ORs) and 95% confidence intervals (CIs) for the KOSHA CVD risk groups according to quartiles of skeletal muscle mass indicators were estimated using ordinal logistic regression analysis. Results: The OR for the KOSHA CVD risk groups in the highest quartile of SMI was 1.67 (95% CI: 1.42-1.92), while the ORs for the KOSHA CVD risk groups in the highest quartiles of SMM%, SMM/body mass index (BMI), and MFR were 0.47 (95% CI: 0.22-0.72), 0.51 (95% CI: 0.05-0.76), and 0.48 (95% CI: 0.23-0.74), respectively. Conclusions: We found that high SMI increase the likelihood of high risk of CVDs, while high SMM%, SMM/BMI, and MFR lower the likelihood of high risk of CVDs. Accurate evaluation of skeletal muscle mass can help assess the cardiovascular risk in obese male workers.

• 대한치과교정학회지
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• 제42권1호
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• pp.11-16
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• 2012

Objective: This study aimed to evaluate the mean age of menarche, its secular trend in Korean women, and the relationship between malocclusion and the rate of skeletal maturation, as defined by menarcheal age. Methods: We retrospectively collected data on menarcheal age from 931 Korean women born during 1961 - 1997. Subjects were divided by the malocclusion type and birth-year decade into 3 and 4 groups, respectively. The mean menarcheal age for each group was determined, and one-way ANOVA was performed for intergroup comparison (p = 0.05). Two-way ANOVA was also performed to compare all the 12 subgroups (p = 0.05). Results: The mean age of menarche was 12.82 years for Korean women born during 1961 - 1997. A distinct downward secular trend of menarcheal age was noticed (p < 0.05). For the birth-year decade 1961 - 1970, the Class III malocclusion group showed earlier onset of menarche than the other malocclusion groups (p < 0.05), but the other birth-year groups did not show any significant difference in the type of malocclusion (p > 0.05). Conclusions: A positive secular trend towards earlier menarche exists among Korean women. Malocclusion does not show any significant relationship with the rate of skeletal maturation, as defined by menarcheal age.

• Journal of Yeungnam Medical Science
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• 제34권1호
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• pp.19-28
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• 2017

The incidence of type 2 diabetes mellitus and insulin resistance is growing rapidly. Multiple organs including the liver, skeletal muscle and adipose tissue control insulin sensitivity coordinately, but the mechanism of skeletal muscle insulin resistance has not yet been fully elucidated. However, there is a growing body of evidence that lipotoxicity induced by mitochondrial dysfunction in skeletal muscle is an important mediator of insulin resistance. However, some recent findings suggest that skeletal mitochondrial dysfunction generated by genetic manipulation is not always correlated with insulin resistance in animal models. A high fat diet can provoke insulin resistance despite a coordinate increase in skeletal muscle mitochondria, which implies that mitochondrial dysfunction is not mandatory in insulin resistance. Furthermore, incomplete fatty acid oxidation by excessive nutrition supply compared to mitochondrial demand can induce insulin resistance without preceding impairment of mitochondrial function. Taken together we suggested that skeletal muscle mitochondrial overloading, not mitochondrial dysfunction, plays a pivotal role in insulin resistance.

• Journal of Periodontal and Implant Science
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• 제45권1호
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• pp.8-13
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• 2015

Purpose: The aim of this study was to evaluate the transfer of different occlusal forces in various skeletal malocclusions using finite element analysis (FEA). Methods: Three representative human cone-beam computed tomography (CBCT) images of three skeletal malocclusions were obtained from the Department of Orthodontics, Yonsei University Dental Hospital, Seoul, South Korea. The CBCT scans were read into the visualization software after separating bones and muscles by uploading the CBCT images into Mimics (Materialise). Two separate three-dimensional (3D) files were exported to visualize the solid morphology of skeletal outlines without considering the inner structures. Individual dental impressions were taken and stone models were scanned with a 3D scanner. These images were integrated and occlusal motions were simulated. Displacement and Von Mises stress were measured at the nodes of the FEA models. The displacement and stress distribution were analyzed. FEA was performed to obtain the 3D deformation of the mandibles under loads of 100, 150, 200, and 225 kg. Results: The distortion in all three skeletal malocclusions was comparable. Greater forces resulted in observing more distortion in FEA. Conclusions: Further studies are warranted to fully evaluate the impact of skeletal malocclusion on masticatory performance using information on muscle attachment and 3D temporomandibular joint movements.

• 대한치과교정학회지
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• 제32권2호통권91호
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• pp.91-105
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• 2002

일반적으로 교정 환자의 문제점을 파악하고 치료 계획을 수립할 때에 여러 분석법의 정상치를 기준으로 하는 경우가 많다. 하지만 다양한 악골관계 하에서 정상적인 악궁관계를 유지하기 위해 3차원적으로 발생하는 치아치조부 보상 기전을 고려한다면 좀 더 개별화된 치료 목표와 치료계획을 수립하는데 도움이 될 수 있을 것이다. 이에 본 연구에서는 정상교합자 125명의 측모 두부계측방사선사진을 계측하여 정상교합자의 골격양상의 다양성을 살펴보았다. 또한 여러 골격계측 기준을 이용한 군집분석을 적용하여 정상교합자의 골격형을 전후방으로 세 군, 수직적으로 세 군으로 분류하고 각 골격형에 따른 치아치조부 보상양상을 조사하여 다음과 같은 결과를 얻었다. 1. 정상교합자의 전후방적, 수직적 악골관계는 매우 다양하였다. 2. 하악골이 상악골에 비해 전방 위치할수록 상악 전치는 순측으로 경사 되고 하악 전치는 설측으로 경사 되며 교합평면의 경사도는 완만해졌다. 3. 수직적인 골격양상일수록 상악 전치부의 치아치조 고경이 증가하고, 하악 구치부의 치아치조 고경이 감소하였으며 구개평면에 대한 상악 구치와 하악평면에 대한 하악 전치 및 하악 구치는 직립 하였고 교합평면과 하악평면사이의 각(OMA)은 증가하였다. 4. 상악 전치보다 하악 전치에서 전후방 및 수직적인 악골관계에 대해 더 많은 치아치조부 보상양상을 보였다.

• BMB Reports
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• 제44권10호
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• pp.613-618
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• 2011

Two key molecules in skeletal tissues are bone formation master transcription factor Runx2 and the steroid hormone estrogen. It is well known that these two molecules play pivotal roles in bone homeostasis; however, the functional interaction between Runx2 and estrogen synthesis in skeletal tissues is largely unknown. Recent studies have indicated that there is a positive relationship between Runx2 and the estrogen biosynthesis pathway. In this review, a possible functional link between Runx2 and estrogen synthesis pathway in skeletal tissues will be discusses as well as the biological significance of this interaction.

• 대한치과의사협회지
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• 제37권10호통권365호
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• pp.772-779
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• 1999

• 대한치과교정학회지
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• 제30권2호
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• pp.175-183
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• 2000

대학에 재학 중인 성인 남녀의 구강검사를 통해 대구치의 전후방관계는 Angle씨 I급 관계를 보이고, 전치부는 정상범위내의 수평피개교합 및 수직피개교합를 지니면서 교정치료의 경험이 없는 남자 51명 여자 50명, 합계 101명 (평균 나이: 남자 23.6세, 여자 21.5세)의 표본을 연구대상으로 하여 다양한 악골관계에 따라 정상교합을 이루기 위한 치아, 치조의 보상적 변화의 양상을 상하악골과 치아, 치조의 배열간의 상관관계를 분석하여 파악한 결과, 다음과 같은 결론을 얻었다. 1. 정상교합의 표본에서도 전후방적, 수직적 악골관계 및 치아, 치조관계를 나타내는 변수의 계측치들은 그 변이의 정도가 매우 다양하였다. 2. 상하악전치의 치축경사도는 악골의 전후방적 위치관계와 높은 상관관계를 보였으며 상악골에 대하여 하악골이 후방에 위치할수록 상악전치는 설측경사, 하악전치는 순측경사의 경향을 보였다 (P<0.01). 3. 상하악 치조의 높이는 악골의 수직적 위치관계를 나타내는 하안면고경의 크기와 매우 높은 상관관계를 보였다. 4. 상하악 치조의 높이와 악골의 전후방적인 위치관계에 대해서는 상호간의 관련성이 없었다 (p>0.05). 5.상하악 전치의 치축경사와 악골의 수직적 위치와의 관계는 상악전치부가 하악 전치부에 비해 더욱 긴밀히 관련되었다. 이상의 연구에서 정상적인 교합을 보이는 경우에도 개인에 따라 악골의 배열 및 치아, 치조의 배열에 있어서 차이가 많음을 인식할 수 있으며, 악골의 전후방적 위치와 전치부 치축경사도간, 그리고 악골의 수직고경과 상하악 전치부 치조의 높이간에는 밀접한 관련성이 있고 이는 달라진 악골의 위치에 따른 보상적 변화로 결론 지을 수 있을 것이다.ine을 병용할 경우 방사선조사효과는 증강되며, 저산소상태에 있는 마우스 종양에서의 증강효과가 대조 종양에서의 증강효과와 동일하거나 더욱 양호할 가능성을 제시할 수 있었다.었으나 $7.4\%$만이 심한 증상을 보였고, 만성 합병증은 $7.9\%$에서 관찰되었으며, 장폐색, 비뇨기계증상의 악화, 방사선 방광염등의 순이었다.전에 예방하기 위해 중점 관리해야 할 지점에 대해 더 많은 정보를 얻을 수 있으리라고 사료된다.이었고(p<0.01) 포장에 대해서는 주택형태에 따라 농가나 아파트에 거주하는 주부가 단독주택이나 연립주택에 거주하는 주부보다 더 나쁘게 평가하는 경향이었다. (p<0.05) (9) 조사대상주부들은 시판제품의 가장 개선해야 할 점으로 위생성(37.0%), 가격(23.8%), 포장(15.6%), 맛(11.1%), 저장성(10.1%) 및 색(2.4%) 등의 순으로 지적하였고 주부의 거주지에 따라 대도시에 거주할수록 위생성을, 농어촌에 거주할수록 가격을 가장 개선해야 할 점으로 보는 경향이었다. (p<0.05)3.2%는 채소에는 cholesterol이 함유되어 있지 않으므로 채식이 건강에 좋다고 하였다. 또한 질병치료에 유효한 채소는 당근 등 42가지, 질병을 유발시키는 채소는 고사리 등 10종을 지적하였으며 이들은 과학적 증명이 가능하거나 민간요법으로 전해지고 있는 내용이다. 이상과 같이 덕성여자대학교 평생교육원에 다니는 주부의 채소 소비 형태에 대하여 살펴보았는데 가공된 채소반찬과 김치의 구입은 현재까지 일반화되지 않고 있음을 알 수 있으나 김치보다 채소반찬의 구입경험이 더 많은 것으로 나타났다. 본 논문은 덕성여자대학교 평생교육원에 다

• 대한한방소아과학회지
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• 제26권3호
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• pp.1-11
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• 2012

Objectives The purpose of this study is to examine the relationship between skeletal maturity and heart rate variability (HRV) based on the bone age and HRV parameters. Methods 103 children from 6 years to 17 years of age, who do not have any disease-related symptom, and visited ${\bigcirc}{\bigcirc}$ oriental medicine hospital, are measured based on their bone age and short-term spectral analysis of HRV. Results 1. Skeletal maturity was significantly correlated with HRV indices: mean HRT and SDNN. As the skeletal maturity increases, the mean HRT was decreased and the SDNN was increased. 2. When classifying according to the skeletal maturity score, the mean HRT was higher in the 'below -0.4' group compare to '-0.3~0.7' group and '0.8~1.9' group. SDNN was higher in the '0.8~1.9' group compare to '-0.3~0.7' group, 'below -0.4' group 3. When classifying according to the sex, age and secondary sexual characteristics, as the skeletal maturity was increased, the mean HRT was significantly decreased and the SDNN was significantly increased only in the boys who did not develop secondary sexual characteristics. Conclusions Skeletal maturity could be statistically significant with HRV indices, especially to the boys and the children than the girls and the teenagers.