• 제목/요약/키워드: Single domain model

검색결과 245건 처리시간 0.028초

In Silico Evaluation of Deleterious SNPs in Chicken TLR3 and TLR4 Genes

  • Shin, Donghyun;Song, Ki-Duk
    • 한국가금학회지
    • /
    • 제45권3호
    • /
    • pp.209-217
    • /
    • 2018
  • The innate immune recognition is based on the detection of microbial products. Toll-like receptors (TLRs) located on the cell surface and the endosome senses microbial components and nucleic acids, respectively. Chicken TLRs mediate immune responses by sensing ligands from pathogens, have been studied as immune adjuvants to increase the efficacy of vaccines. Single nucleotide polymorphisms (SNPs) of TLR3 and TLR4 genes in chicken were associated with resistance and susceptibility to viral infection. In this study, SNPs of chTLR3 and chTLR4 genes were retrieved from public database and annotated with chicken reference genome. Three-dimensional models of the chTLR3 and chTLR4 proteins were built using a Swiss modeler. We identified 35 and 13 nsSNPs in chTLR3 and chTLR4 genes respectively. Sorting Intolerant from Tolerant (SIFT) and Polymorphism Phenotyping v2 (Polyphen-2) analyses, suggested that, out of 35 and 13 nsSNPs, 4 and 2 SNPs were identified to be deleterious in chTLR3 and chTLR4 gene respectively. In chTLR3, 1 deleterious SNP was located in ectodomain and 3 were located in the Toll / IL-1 receptor (TIR) domain. Further structural model of chTLR3-TIR domain suggested that 1 deleterious SNP be present in the B-B loop region, which is important for TIR-TIR domain interactions in the downstream signaling. In chTLR4, the deleterious SNPs were located both in the ectodomain and TIR domain. SNPs predicted for chTLR3 and chTLR4 in this study, might be related to resistance or susceptible to viral infection in chickens. Results from this study will be useful to develop the effective measures in chicken against infectious diseases.

Frequency Domain Channel Estimation for MIMO SC-FDMA Systems with CDM Pilots

  • Kim, Hyun-Myung;Kim, Dongsik;Kim, Tae-Kyoung;Im, Gi-Hong
    • Journal of Communications and Networks
    • /
    • 제16권4호
    • /
    • pp.447-457
    • /
    • 2014
  • In this paper, we investigate the frequency domain channel estimation for multiple-input multiple-output (MIMO) single-carrier frequency-division multiple-access (SC-FDMA) systems. In MIMO SC-FDMA, code-division multiplexed (CDM) pilots such as cyclic-shifted Zadoff-Chu sequences have been adopted for channel estimation. However, most frequency domain channel estimation schemes were developed based on frequency-division multiplexing of pilots. We first develop a channel estimation error model by using CDM pilots, and then analyze the mean-square error (MSE) of various minimum MSE (MMSE) frequency domain channel estimation techniques. We show that the cascaded one-dimensional robust MMSE (C1D-RMMSE) technique is complexity-efficient, but it suffers from performance degradation due to the channel correlation mismatch when compared to the two-dimensional MMSE (2D-MMSE) technique. To improve the performance of C1D-RMMSE, we design a robust iterative channel estimation (RITCE) with a frequency replacement (FR) algorithm. After deriving the MSE of iterative channel estimation, we optimize the FR algorithm in terms of the MSE. Then, a low-complexity adaptation method is proposed for practical MIMO SC-FDMA systems, wherein FR is performed according to the reliability of the data estimates. Simulation results show that the proposed RITCE technique effectively improves the performance of C1D-RMMSE, thus providing a better performance-complexity tradeoff than 2D-MMSE.

A Domain-independent Dual-image based Robust Reversible Watermarking

  • Guo, Xuejing;Fang, Yixiang;Wang, Junxiang;Zeng, Wenchao;Zhao, Yi;Zhang, Tianzhu;Shi, Yun-Qing
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • 제16권12호
    • /
    • pp.4024-4041
    • /
    • 2022
  • Robust reversible watermarking has attracted widespread attention in the field of information hiding in recent years. It should not only have robustness against attacks in transmission but also meet the reversibility of distortion-free transmission. According to our best knowledge, the most recent robust reversible watermarking methods adopt a single image as the carrier, which might lead to low efficiency in terms of carrier utilization. To address the issue, a novel dual-image robust reversible watermarking framework is proposed in this paper to effectively utilize the correlation between both carriers (namely dual images) and thus improve the efficiency of carrier utilization. In the dual-image robust reversible watermarking framework, a two-layer robust watermarking mechanism is designed to further improve the algorithm performances, i.e., embedding capacity and robustness. In addition, an optimization model is built to determine the parameters. Finally, the proposed framework is applied in different domains (namely domain-independent), i.e., Slantlet Transform and Singular Value Decomposition domain, and Zernike moments, respectively to demonstrate its effectiveness and generality. Experimental results demonstrate the superiority of the proposed dual-image robust reversible watermarking framework.

An Ensemble Model for Credit Default Discrimination: Incorporating BERT-based NLP and Transformer

  • Sophot Ky;Ju-Hong Lee
    • 한국정보처리학회:학술대회논문집
    • /
    • 한국정보처리학회 2023년도 춘계학술발표대회
    • /
    • pp.624-626
    • /
    • 2023
  • Credit scoring is a technique used by financial institutions to assess the creditworthiness of potential borrowers. This involves evaluating a borrower's credit history to predict the likelihood of defaulting on a loan. This paper presents an ensemble of two Transformer based models within a framework for discriminating the default risk of loan applications in the field of credit scoring. The first model is FinBERT, a pretrained NLP model to analyze sentiment of financial text. The second model is FT-Transformer, a simple adaptation of the Transformer architecture for the tabular domain. Both models are trained on the same underlying data set, with the only difference being the representation of the data. This multi-modal approach allows us to leverage the unique capabilities of each model and potentially uncover insights that may not be apparent when using a single model alone. We compare our model with two famous ensemble-based models, Random Forest and Extreme Gradient Boosting.

Development of a flux emergence simulation using parallel computing

  • 이환희;마가라 테츠야
    • 천문학회보
    • /
    • 제44권2호
    • /
    • pp.71.1-71.1
    • /
    • 2019
  • The solar magnetic field comes from the solar interior and is related to various phenomena on the Sun. To understand this process, many studies have been conducted to produce its evolution using a single flux rope. In this study, we are interested in the emergence of two flux ropes and their evolution, which takes longer than the emergence of a single flux rope. To construct it, we develop a flux emergence simulation by applying a parallel computing to reduce a computation time in a wider domain. The original simulation code had been written in Fortran 77. We modify it to a version of Fortran 90 with Message Passing Interface (MPI). The results of the original and new simulation are compared on the NEC SX-Aurora TSUBASA which is a vector engine processor. The parallelized version is faster than running on a single core and it shows a possibility to handle large amounts of calculation. Based on this model, we can construct a complex flux emergence system, such as an evolution of two magnetic flux ropes.

  • PDF

Rank-weighted reconstruction feature for a robust deep neural network-based acoustic model

  • Chung, Hoon;Park, Jeon Gue;Jung, Ho-Young
    • ETRI Journal
    • /
    • 제41권2호
    • /
    • pp.235-241
    • /
    • 2019
  • In this paper, we propose a rank-weighted reconstruction feature to improve the robustness of a feed-forward deep neural network (FFDNN)-based acoustic model. In the FFDNN-based acoustic model, an input feature is constructed by vectorizing a submatrix that is created by slicing the feature vectors of frames within a context window. In this type of feature construction, the appropriate context window size is important because it determines the amount of trivial or discriminative information, such as redundancy, or temporal context of the input features. However, we ascertained whether a single parameter is sufficiently able to control the quantity of information. Therefore, we investigated the input feature construction from the perspectives of rank and nullity, and proposed a rank-weighted reconstruction feature herein, that allows for the retention of speech information components and the reduction in trivial components. The proposed method was evaluated in the TIMIT phone recognition and Wall Street Journal (WSJ) domains. The proposed method reduced the phone error rate of the TIMIT domain from 18.4% to 18.0%, and the word error rate of the WSJ domain from 4.70% to 4.43%.

Inter-Grain Exchange Interaction and Hysteresis Loops of Melt-Spun $Nd_{13}Fe_{77}B_{10}$

  • J. H. Min;Kim, Y. B.;Park, W. S.;Park, M. J.;Li Tian
    • Journal of Magnetics
    • /
    • 제1권2호
    • /
    • pp.69-74
    • /
    • 1996
  • Justeresos loops of melt-spun Nd13Fe77B10 cooled down at remanent state were measured at 4.2 K and 250 K. The hysteresis loops were analysed on the basis of the Stoner-Wohlfarth (S-W) model, the inter-grain exchange coupled single domain (SD) model and micromagnetism. The coercivity higher than that predicted from the S-W model and the striking shift of the thin minor loop along the H-axix observed at the fields of Hmax=4MA/m at 4.2 K indicated new evidences for the inter-grain exchange interaction . The S-W model failed in explaining the high iHc and the shift of the thin minor loop. The exchange coupled SD model was found to explain the experimental results qualitatively without difficulties associated with the S-W model. The micromagnetic calculations using a finite element technique simulated the experimental results fairly well quntitatively.

  • PDF

직렬-병렬 공진 무선전력전송 시스템의 동기 좌표계 모델 (DQ Synchronous Reference Frame Model of a Series-Parallel Tuned Inductive Power Transfer System)

  • 노은총;이상민;이승환
    • 전력전자학회논문지
    • /
    • 제25권6호
    • /
    • pp.477-483
    • /
    • 2020
  • This study proposes a DQ synchronous reference frame model of a series-parallel tuned inductive power transfer (SP-IPT) system. The wireless power transmission system experiences control difficulty because the transmitter-side controller cannot directly measure the receiver-side load voltages and currents. Therefore, a control-oriented circuit model that shows the dynamics of the IPT system is required to achieve a well-behaved controller. In this study, an equivalent circuit model of the SP-IPT system in a synchronously rotating reference frame is proposed using the single-phase DQ transformation technique. The proposed circuit model is helpful in modeling the dynamics of the voltages and currents of the transmitter- and receiver-side resonant tanks and loads. The proposed circuit model is evaluated using frequency- and time-domain simulation results.

Physics on cancer and its curing

  • Oh, Hung-Kuk
    • 한국감성과학회:학술대회논문집
    • /
    • 한국감성과학회 2000년도 추계학술대회 논문집
    • /
    • pp.91-97
    • /
    • 2000
  • The conventional model did not take momentum conservation into consideration when the electron absorbs and emits the photons. II-ray provides momentum conservations on any directions of the entering photons, and also the electrons have radial momentum conservations and fully elastic bouncing between two atoms, in the new atom model. Conventional atom model must be criticized on the following four points. (1) Natural motions between positive and negative entities are not circular motions but linear going and returning ones, for examples sexual motion, tidal motion, day and night etc. Because the radius of hydrogen atom's electron orbit is the order of 10$^{-11}$ m and the radia of the nucleons in the nucleus are the order of 10$^{-l4}$m and then the converging n-gamma rays to the nucleus have so great circular momentum, the electron can not have a circular motion. We can say without doubt that any elementary mass particle can have only linear motion because of the n-rays' hindrances, near the nucleus. (2) Potential energy generation was neglected when electron changes its orbit from outer one to inner one. The h v is the kinetic energy of the photo-electron. The total energy difference between orbits comprises kinetic and potential energies. (3) The structure of the space must be taken into consideration because the properties of the electron do not change during the transition from outer orbit to inner one even though it produces photon. (4) Total energy conservation law applies to the energy flow between mind and matter because we daily experiences a interconnection between mind and body. An understanding of the mechanisms responsible for the control of normal proliferation and differentiation of the various cell types which make up the human body will undoubtedly allow a greater insight into the abnormal growth of cells, A large body of biochemical evidence was eventually used to generate a receptor model with an external ligand binding domain linked through a single trans-membrane domain to the cytoplasmic tyrosine kinase and autophosphory-lation domains. The ligand induced conformational change in the external domain generates either a push-pull or rotational signal which is transduced from the outside to the inside of cell.l.ell.

  • PDF

FDTD 방법을 이용한 단일 계단형 마이크로스트립 기판 불연속의 등가회로 개발 (Finite-Difference Time-Domain Approach for the development of an Equivalent Circuit for a Single Step Microstrip Discontinuity in the Substrate)

  • 전중창;김태수;한대현;박위상
    • 한국전자파학회논문지
    • /
    • 제11권7호
    • /
    • pp.1240-1246
    • /
    • 2000
  • 본 논문에서는 유한차분 시간영역 방법을 적용하여 단일 계단형 마이크로스트립 기판 불연속 구조를 해석하였으며, 이 결과를 사용하여 LC 등가회로를 구성하였다. 본 논문에서 제안된 구조는 마이크로스트립 선로의 길이 방향으로 계단형 기판 불연속을 가지며, 패치 안테나의 급전선, 회로 모듈간 연결 등에 적용될 수 있다. FDTD 해석결과는 HFSS를 이용하여 얻어진 결과와 비교하여 잘 일치함을 보였다. 개발된 등가회로는 S11과 S21 모두 2.4% 이내의 정확도를 가지며, 마이크로파 회로의 CAD 설계에 응용될 수 있다.

  • PDF