• Genomics & Informatics
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• v.18 no.1
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• pp.11.1-11.3
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• 2020

In genome-wide association studies, pathway-based analysis has been widely performed to enhance interpretation of single-nucleotide polymorphism association results. We proposed a novel method of hierarchical structural component model (HisCoM) for pathway analysis of common variants (HisCoM for pathway analysis of common variants [HisCoM-PCA]) which was used to identify pathways associated with traits. HisCoM-PCA is based on principal component analysis (PCA) for dimensional reduction of single nucleotide polymorphisms in each gene, and the HisCoM for pathway analysis. In this study, we developed a HisCoM-PCA software for the hierarchical pathway analysis of common variants. HisCoM-PCA software has several features. Various principle component scores selection criteria in PCA step can be specified by users who want to summarize common variants at each gene-level by different threshold values. In addition, multiple public pathway databases and customized pathway information can be used to perform pathway analysis. We expect that HisCoM-PCA software will be useful for users to perform powerful pathway analysis.

• Applied Biological Chemistry
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• v.2
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• pp.36-39
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• 1961

It has been ascertained that S-(1, 2-dichlorovinyl) L-cysteine (DCVC) is probably the toxic component in the trichloro-ethylene extracted soybean oil meal on the bovine. For the study of the metabolites of DCVC, the components with radioactive $S^{35}$-in the urine of the calf, to which $S^{35}$-DCVC was administrated, were separated using of cellulose powder with propanol-water (70:30 V/V) which is easily removable by evaporation. As the results followings were obtained: Peak 1, which shows fractions containing single $S^{35}$-radioactive components, whose Rf is 0.815 Peak 2, which shows fractions containing jingle $S^{35}$-radioactive component, whose Rf is 0.447 Peak 3, which shows fractions containing both $S^{35}$-radioactive components whose Rfs are 0.090 and 0.171 Peak 4, which shows fractions containing single $S^{35}$-radioactive component, whose Rf is 0.142. Peak 5, which shows fractions containing single $S^{35}$-radioactive component, whose Rf is 0.084. Besides these, two of small peak were obtained. Although, the resolving power of the cellulose powder column is not sufficient, it is applicable for the study of the components of metabolytes of DCVC conveniently with the rest of removable solvent easily. Also the components with radioactive $S^{35}$ in the feces of the calf were separated using citrate buffer gradient system of Moore and stein. As the results; three $S^{35}$-radioactive components were separated.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.924-925
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• 2008

There are many types of grid-connected inverter controllers, PI controller based is the most popular methods. But, a common PI control is produced zero-steady state error and phase delay in sinusoidal reference. Synchronous reference frame or DQ transform based controller is capable for reducing both of zero-steady state error and phase delay is. But DQ transform based controller has cross-coupling component which difficult to analyze the system in single phase model. In this paper, to obtained single phase model of the system, DQ transform based controller is analyzed in two techniques. The first is by neglecting cross-coupling. The second is eliminated cross-coupling component by decoupling method. By these two techniques, single phase model is obtained. Then, the single phase model is analyzed to evaluate its performance in stability and frequency response, through Root Locus and Bode diagram, respectively. MATLAB and PSIM simulation is used to verify the analysis. Simulation result is shown; cross-coupling component has no significant influent to the controller.

• Nuclear Engineering and Technology
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• v.43 no.1
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• pp.13-18
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• 2011

In this study, simulations were done of a 661.6 keV line from a point source of $^{137}Cs$ housed in a lead shield. When increasing the scattering angle from 60 to 120 degrees with a 6061 aluminum alloy target placed at angles of 30 and 45 degrees to the incident beam, the spectra showed that the single scattering component increases and that the multiple scattering component decreases. The investigation of the single and multiple scattering components was carried out using a MCNP5 simulation code. The component of the single Compton scattering photons is proportional to the target electron density at the point where the scattering occurs. The single scattering peak increases according to the thickness of the target and saturates at a certain thickness. The signal-to-noise ratio was found to decrease according to the target thickness. The simulation was experimentally validated by measurements. These results will be used to determine the best conditions under which this method can be applied to testing electron densities or to assess the thickness of samples to locate defects in them.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.33 no.5
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• pp.373-380
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• 2009

The evaporation process of multi-component fuel is different from one of a single component, because the properties of each component affects among the components. In actual engine, the spatial distribution of fuel vapor concentration dominates auto-ignition and initial combustion, and depends on the volatility and diffusivity of each component fuel contained in the multi-component fuel. Then, this study proposes a simplified numerical scheme for analysis of evaporation process of multi-component fuel sprays. Evaporation process is calculated by KIVA-II code based on the simple two-phases region that is approximated by modified saturated liquid-vapor line, which was obtained by connecting the 50% distillation temperature for each component under several pressure fields. Consequently, it can be quantitatively simulated that vapor of low boiling fuel component mostly exists around nozzle and spray tip region, the high boiling duel component, on the other hand, mostly appears near the spray tip.

• Proceedings of the Korean Fiber Society Conference
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• 2003.10a
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• pp.5-6
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• 2003

Kinetic study on the colloidal crystallization of single component and mixture of different sizes or densities of spheres was made in the exhaustively deionized suspensions and in microgravity, and compared with the results in normal gravity. Colloidal crystallization rates were retarded in microgravity for single component of spheres, whereas rates of alloy crystallization were enhanced substantially in microgravity. The rotational diffusion coefficients of colloids and the formation reaction rates of colloidal silica spheres were also studied in microgravity.

• The Transactions of the Korean Institute of Power Electronics
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• v.22 no.6
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• pp.510-516
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• 2017

This paper proposes a single-stage interleaved totem-pole on-board battery charger with a simple structure and a reduced component count. Apart from achieving ZVS turn-on of all switches and ZCS turn-off of all diodes, this charger does not require an input filter due to its CCM operation and bulky electrolytic capacitors, which in turn result in a high power density. A single-stage power conversion technique is applied to the interleaved structure in order to achieve a high power density and high efficiency. A 2.5 kW prototype of the proposed charger is also built and tested to validate the proposed operation.

• IEMEK Journal of Embedded Systems and Applications
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• v.14 no.4
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• pp.197-205
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• 2019

In this paper, an efficient single dehazing algorithm is proposed based on linear transformation by assuming that a linear relationship exists in saturation component between the haze image and haze-free image. First, we analyze the linearity of saturation channel, estimate the medium transmission map in terms of the saturation component. Then, the intensity of haze-free image is assumed by using CLAHE to enhance contrast of haze image. Experimental results demonstrate that proposed algorithm can naturally recover the image, especially can remove color distortion caused by conventional methods. Therefore, our approach is competitive with other state-of-the art single dehazing methods.

• Proceedings of the IEEK Conference
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• 2000.07a
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• pp.399-402
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• 2000

The reduction of chip area and delay is important purpose of Scheduling in High-Level Synthesis. This paper presents a scheduling approach with component selection. After obtaining a initial schedule taking only single-functional u-nits, the component selection of our approach attempts the reduction of chip area and/or delay by the selection more suitable components in a component library using Simulated Annealing.

• The Transactions of the Korean Institute of Power Electronics
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• v.23 no.2
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• pp.94-100
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• 2018

Generally, in a single-phase energy storage system (ESS) for households, AC ripple component with twice the fundamental frequency exists inevitably in the DC link voltage of single-phase PCS. In the grid-connected mode of a single-phase inverter, the AC ripple component in the DC link voltage causes low-order harmonics on grid-side current that deteriorates power quality on an AC grid. In this work, a control system adopting a feedforward controller is established to eliminate the AC ripple interference on the DC link side. Optimal battery nominal voltage design method is also proposed by considering the voltage loss and AC ripple voltage on DC link side in a single-phase ESS. Finally, the control system and battery nominal voltage design method are verified through simulations and experiments.