• Journal of Korean Neurosurgical Society
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• v.62 no.1
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• pp.61-70
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• 2019

Objective : Corpectomy of the first lumbar vertebra (L1) for the management of different L1 pathologies can be performed using either an anterior or posterior approach. The aim of this study was to evaluate the usefulness of a retroperitoneal extrapleural approach through the twelfth rib for performing L1 corpectomy. Methods : Thirty consecutive patients underwent L1 corpectomy between 2010 and 2016. The retroperitoneal extrapleural approach through the 12th rib was used in all cases to perform single-stage anterior L1 corpectomy, reconstruction and anterior instrumentation, except for in two recurrent cases in which posterior fixation was added. Visual analogue scale (VAS) was used for pain intensity measurement and ASIA impairment scale for neurological assessment. The mean follow-up period was 14.5 months. Results : The sample included 18 males and 12 females, and the mean age was 40.3 years. Twenty patients (67%) had sensory or motor deficits before the surgery. The pathologies encountered included traumatic fracture in 12 cases, osteoporotic fracture in four cases, tumor in eight cases and spinal infection in the remaining six cases. The surgeries were performed from the left side, except in two cases. There was significant improvement of back pain and radicular pain as recorded by VAS. One patient exhibited postoperative neurological deterioration due to bone graft dislodgement. All patients with deficits at least partially improved after the surgery. During the follow-up, no hardware failures or losses of correction were detected. Conclusion : The retroperitoneal extrapleural approach through the 12th rib is a feasible approach for L1 corpectomy that can combine adequate decompression of the dural sac with effective biomechanical restoration of the compromised anterior loadbearing column. It is associated with less pulmonary complication, no need for chest tube, no abdominal distention and rapid recovery compared with other approaches.

• The Journal of Advanced Prosthodontics
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• v.11 no.2
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• pp.95-104
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• 2019

PURPOSE. To evaluate the effect of surface treatments and repair materials on the shear bond strength and to measure the fracture toughness of CAD/CAM provisional restoration materials. MATERIALS AND METHODS. Four CAD/CAM (3D printing: Nextdent C&B and ZMD-1000B Temporary, CAD/CAM resin block: Yamahachi PMMA disk and Huge PMMA block) and four conventional (monometacrylate: Jet and Alike, dimetacrylate: Luxatemp and Protemp 4) materials were selected to fabricate disk-shaped specimens and divided into six groups according to surface treatment (n=10). CAD/CAM materials were repaired with Jet or Luxatemp, while conventional materials were repaired with their own materials. The shear bond strength was measured by using universal testing machine. Ten rectangular column-shaped specimens for each material were fabricated to measure the fracture toughness by single edge v notched beam technique. Statistical analysis was performed by one-way ANOVA. RESULTS. The highest shear bond strength of CAD/CAM materials was achieved by SiC paper + sandblasting. It was also accomplished when repairing 3D printing materials with Luxatemp, and repairing CAD/CAM resin blocks with Jet. Yamahachi PMMA disk showed the highest fracture toughness. Nextdent C&B showed the lowest fracture toughness value but no statistically significant difference from Alike and Luxatemp (P>.05). CONCLUSION. In order to successfully repair the CAD/CAM provisional restoration, mechanical surface treatment and appropriate repair material according to the CAD/CAM material type should be selected. The CAD/CAM provisional materials have proper mechanical properties for clinical use as compared to conventional materials.

• Korean Journal of Anesthesiology
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• v.71 no.6
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• pp.453-458
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• 2018

Background: Pain on injection is a limitation with propofol use. The effect of the Valsalva maneuver on pain during propofol injection has not been studied. This maneuver reduces pain through the sinoaortic baroreceptor reflex arc and by distraction. We aimed to assess the efficacy of the Valsalva maneuver in reducing pain during propofol injection. Methods: Eighty American Society of Anesthesiologists class I adult patients undergoing general anesthesia were enrolled and divided into two groups of 40 each. Group I (Valsalva) patients blew into a sphygmomanometer tube raising the mercury column up to 30 mmHg for 20 seconds, while Group II (Control) patients did not. Anesthesia was induced with 1% propofol immediately afterwards. Pain was assessed on a 10-point visual analog scale (VAS), where 0 represented no pain, and 10, the worst imaginable pain, and a 4-point withdrawal response score, where 0 represented no pain, and 3, the worst imaginable pain. Scores were presented as median (interquartile range). Results: We analyzed the data of 70 patients. The incidence of pain was significantly lower in the Valsalva than in the control group (53% vs. 78%, P = 0.029). The withdrawal response score was significantly lower in the Valsalva group (1.00 [0.00-1.00] vs. 2.00 [2.00-3.00], P < 0.001). The VAS score was significantly lower in the Valsalva group (1.00 [0.00-4.00] vs. 7.00 [6.25-8.00], P < 0.001). Conclusions: A prior Valsalva maneuver is effective in attenuating injection pain due to propofol; it is advantageous in being a non-pharmacological, safe, easy, and time-effective technique.

• Journal of The Korean Astronomical Society
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• v.54 no.1
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• pp.9-16
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• 2021

The Ozone Dynamics Investigation Nano-Satellite (ODIN) is a CubeSat design proposed by Chungnam National University as contribution to the CubeSat Competition 2019 sponsored by the Korean Aerospace Research Institute (KARI). The main objectives of ODIN are (1) to observe the polar ozone column density (latitude range of 60° to 80° in both hemispheres) and (2) to investigate the chemical dynamics between stratospheric ozone and ozone depleting substances (ODSs) through spectroscopy of the terrestrial atmosphere. For the operation of ODIN, a highly efficient power system designed for the specific orbit is required. We present the conceptual structural design of ODIN and an analysis of power generation in a sun synchronous orbit (SSO) using two different configurations of 3U solar panels (a deployed model and a non-deployed model). The deployed solar panel model generates 189.7 W through one day which consists of 14 orbit cycles, while the non-deployed solar panel model generates 152.6 W. Both models generate enough power for ODIN and the calculation suggests that the deployed solar panel model can generate slightly more power than the non-deployed solar panel model in a single orbit cycle. We eventually selected the non-deployed solar panel model for our design because of its robustness against vibration during the launch sequence and the capability of stable power generation through a whole day cycle.

• Current Optics and Photonics
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• v.5 no.4
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• pp.431-443
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• 2021

Sparse unmixing has been proven to be an effective method for hyperspectral unmixing. Hyperspectral images contain rich spectral and spatial information. The means to make full use of spectral information, spatial information, and enhanced sparsity constraints are the main research directions to improve the accuracy of sparse unmixing. However, many algorithms only focus on one or two of these factors, because it is difficult to construct an unmixing model that considers all three factors. To address this issue, a novel algorithm called multiview-based spectral weighted and low-rank row-sparsity unmixing is proposed. A multiview data set is generated through spectral partitioning, and then spectral weighting is imposed on it to exploit the abundant spectral information. The row-sparsity approach, which controls the sparsity by the l_2,0 norm, outperforms the single-sparsity approach in many scenarios. Many algorithms use convex relaxation methods to solve the l_2,0 norm to avoid the NP-hard problem, but this will reduce sparsity and unmixing accuracy. In this paper, a row-hard-threshold function is introduced to solve the l_2,0 norm directly, which guarantees the sparsity of the results. The high spatial correlation of hyperspectral images is associated with low column rank; therefore, the low-rank constraint is adopted to utilize spatial information. Experiments with simulated and real data prove that the proposed algorithm can obtain better unmixing results.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.36 no.2
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• pp.105-112
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• 2023

In this study, structural analyses were conducted to analyze the performance of a bridge to which friction pendulum systems (FPSs) were applied using different friction models. A Coulomb friction model and a rate dependent friction model were constructed using the friction coefficient of a PVDF/MgO friction material to analyze the effect of different friction analysis models. The Coulomb friction model uses a single friction coefficient regardless of friction velocity, while the rate dependent friction model can reflect the change in the friction coefficient with friction velocity. Nonlinear time history and seismic fragility analyses were conducted to confirm responses of the bridge. The seismic responses of a deck and a column were used to evaluate the performance of the base isolated bridge, and a friction model that can effectively evaluate the performance of isolated bridges was analyzed.

• Geomechanics and Engineering
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• v.36 no.3
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• pp.217-229
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• 2024

Determining lateral earth pressure coefficient (EPC) K is a classic problem in geotechnical engineering. It is a key parameter for estimating the stresses in backfilled openings. For backfilled openings with rigid and immobile walls, some suggested using the Jaky's at-rest earth pressure coefficient K₀ while other suggested taking the Rankine's active earth pressure coefficient K_a. A single value was proposed for the entire backfilled opening. To better understand the distributions of stresses and K in a backfilled opening, a series of laboratory tests have been conducted. The horizontal and vertical normal stresses at the center and near the wall of the opening were measured. The values of K at the center and near the wall were then calculated with the measured horizontal and vertical normal stresses. The results show that the values of K are close to K_a at the center and close to K₀ near the wall. Furthermore, the experimental results show that the horizontal stress is almost the same at the center and near the wall, indicating a uniform distribution from the center to the wall. It can be estimated by analytical solutions using either K_a or K₀. The vertical stress is higher near the center than near the wall. Its analytical estimation can only be done by using K_a at the center and K₀ near the wall. Finally, the test results were used to calibrate a numerical model of FLAC2D, which was then used to analyze the influence of column size on the stresses and K in the backfilled opening.

• Journal of the Korean Society for Railway
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• v.15 no.4
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• pp.413-421
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• 2012

The purpose of this study is to evaluate the structural dynamic behavior under hybrid control system. The hybrid test is to consider the interaction between the numerical and physical models. In this paper, single degree of freedom hybrid test was performed with one-bay, two-story steel frame structure. One column at the first floor was selected as a physical substructure and one actuator was used for applying the displacement load in horizontal direction. El Centro as earthquake waves was inputted and OpenSees was employed as the numerical analysis program for the hybrid real-time simulation. As a result, the total time of the hybrid test was about 9.6% of actual measured seismic period. The experimental results agreed well with the numerical one in terms of the maximum displacement. In nonlinear analysis, however, material nonlinearity made a difference of residual strain. Therefore, this hybrid dynamic test can be used to predict the structural dynamic performance more effectively than shaking table test, because of the spatial and economic limitations.

• Composites Research
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• v.18 no.6
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• pp.9-18
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• 2005

With the wide applications of fiber-reinforced composite material in aero-structures and mechanical parts, the design of composite joints have become a very important research area because the joints are often the weakest areas in composite structures. This paper presents an analytical study of the stress distributions in mechanically single-fastened and multi-fastened composite laminates. The finite element models which treat the pin and hole contact problem using a contact stress analysis are described. A dimensionless stress concentration factor is used to compare the stress distributions in composite laminates quantitatively In the case of single-pin loaded composite laminate, the effects of stacking sequence, the ratio of a hole diameter and the width of a laminate (W/D ratio), the ratio of hole diameter and distance from edge to hole (E/D ratio), friction coefficient and clamping force are considered. In the case of multi-pin loaded composite laminate, the influence of the number of pins, pitch distance, number of rows, row spacing and hole pattern are considered. The results show that P/D ratio and E/D ratio affect more on stress distributions near the hole boundary than the other factors. In the case of multi-pin loaded composite laminate, the stress concentration in the double column case is better than the other cases of multi-pin loaded composite laminate.

• Journal of Pharmaceutical Investigation
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• v.35 no.2
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• pp.123-127
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• 2005

An HPLC method was employed for the determination of ethambutol in human plasma. After addition of internal standard (IS, octylamine, $2\;{\mu}g/mL$) and alkalinization of the plasma with 5 M sodium hydroxide, the drug and IS were extracted into the mixture of chloroform and diethyl ether (40:60, v/v). Following a 15-min vortex-mixing and a 10min centrifugation, the organic phase was spiked with $100{\mu}L$ of phenylethylisocyanate $(2000{\mu}g/mL)$ for chemical derivatization, mixed for 5 min and evaporated to dryness under a stream of nitrogen. The residue was reconstituted with $100{\mu}L$ of mobile phase and $20{\mu}L$ was injected into C18 column with a mobile phase consisting of methanol:water (70:30, v/v). The samples were detected utilizing an ultraviolet detector at 200 nm. The method was specific and validated with a limit of $0.15\;{\mu}g/mL$. Intra- and inter-day precision and accuracy were acceptable for all quality control samples including the lower limit of quantification. The applicability of this method was demonstrated by analysis of human plasma after oral administration of a single 1200-mg dose to 20 healthy subjects. From the plasma ethambutol concentration vs. time curves, the mean AUC was $9.61{\pm}1.64\;{\mu}g{\cdot}hr/mL$ and Cmax of $2.68\;{\mu}g/mL$ reached 2.73 hr after administration. The mean biological half-life of ethambutol was $3.46{\pm}1.21$ hr. Based on the results, this simple and validated assay could readily be used in any pharmacokinetic studies using humans.