• International Journal of Stem Cells
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• v.16 no.4
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• pp.363-375
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• 2023

Stem cells are the foundational cells for every organ and tissue in our body. Cell-based therapeutics using stem cells in regenerative medicine have received attracting attention as a possible treatment for various diseases caused by congenital defects. Stem cells such as induced pluripotent stem cells (iPSCs) as well as embryonic stem cells (ESCs), mesenchymal stem cells (MSCs), and neuroprogenitors stem cells (NSCs) have recently been studied in various ways as a cell-based therapeutic agent. When various stem cells are transplanted into a living body, they can differentiate and perform complex functions. For stem cell transplantation, it is essential to determine the suitability of the stem cell-based treatment by evaluating the origin of stem, the route of administration, in vivo bio-distribution, transplanted cell survival, function, and mobility. Currently, these various stem cells are being imaged in vivo through various molecular imaging methods. Various imaging modalities such as optical imaging, magnetic resonance imaging (MRI), ultrasound (US), positron emission tomography (PET), and single-photon emission computed tomography (SPECT) have been introduced for the application of various stem cell imaging. In this review, we discuss the principles and recent advances of in vivo molecular imaging for application of stem cell research.

• Journal of The Korean Association of Information Education
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• v.18 no.4
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• pp.559-566
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• 2014

This is to understand the neurological dynamic cognitive processes of math learning based on the abstract mappings( level A2), abstract systems(level A3), and single principles(level A4), which are principles of Fischer's cognitive development theory. Math learning requires flexibility to adapt existing brain function in selecting new neurophysiological activities to learn desired knowledge. This study suggests a general statistical framework for the identification of neurological patterns in different abstract learning change with optimal support. We expected that functional brain networks derived from a simple math learning would change dynamically during the supportive learning associated with different abstract levels. Task based patterns of the brain structure and function on representations of underlying connectivity suggests the possible prediction for the success of the supportive learning.

• Proceedings of the KIEE Conference
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• 1997.07f
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• pp.1989-1992
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• 1997

A new soft switching single stage AC-DC full bridge boost converter with unit input power factor and isolated output is presented. Due to using of the non-dissipative snubber in the primary side, a single stage high-power factor isolated full bridge boost converter has a significant reduction of switching losses in main switching devices and output rectifiers of the primary and secondary side, respectively. The non-dissipative snubber adopted in this study is consisted of a snubber capacitor C. and a snubber inductor $L_r$, a fast recovery snubber diode $D_r$, a commutation diode $D_p$. This paper presents the complete operating principles, theoretical analysis and simulation results.

• Proceedings of the KIPE Conference
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• 1999.07a
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• pp.493-496
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• 1999

A new soft switching single stage AC-DC full bridge boost converter with unit input power factor and isolated output is presented in this paper. Due to the use of a non-dissipative snubber on the primary side, a single stage high-power factor isolated full bridge boost converter has a significant reduction of switching losses in the main switching devices. The non-dissipative snubber adopted in this study consists of a snubber capacitor Cr, a snubber inductor Lr, a fast recovery snubber diode Dr, and a commutation diode Dr, and a commutation diode Dp. This paper presents the complete operating principles, theoretical analysis and experimental results.

• Journal of Power Electronics
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• v.7 no.1
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• pp.55-63
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• 2007

This paper proposes a simple unity power factor zero-voltage-transition (ZVT) pulse-width-modulated (PWM) single-phase rectifier, which features reduced switching and conduction losses. The switching loss reduction is achieved by a simple auxiliary commutation circuit, and the conduction loss reduction is achieved by employing a single-stage converter, rather than a typical double-stage converter comprising of a front-end rectifier and a boost rectifier. Furthermore, thanks to good features such as a simple PWM control at constant frequency, low switch stress, low Var rating of commutation circuits, and simple power circuit structure, it is suitable for high power applications. The principles of operation are explained in detail, and a major characteristics analysis and the experimental results of the new converter are also included in this paper.

• The Transactions of the Korean Institute of Power Electronics
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• v.13 no.4
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• pp.263-269
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• 2008

In this paper, an interleaved boost converter (IBC) with ZVT cell using a single resonant inductor in continuous conduction mode (CCM) is proposed. The IBC with the proposed ZVT cell has advantages such as a simple circuit, reduced size and low cost by using a single resonant inductor. It is more suitable for high power applications. The proposed ZVT cell circuit and principles for the IBC are explained in detail. The validity of the IBC with proposed ZVT cell is verified through experimental results.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1994.04a
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• pp.103-111
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• 1994

An interactive and iterative design method based on the constraint satisfaction problem (CSP) technique was developed to generate an ergonomically sound layout of a control panel. This control panel layout method attempts to incorporate a variety of relevant ergonomic principles and design constraints, and generate an optimal or, at least, a "satisfactory" solution through iterative interactions with the designer. The existing panel design and layout methods are mostly based on the optimization of single objective function formulated to reflect and trade off all ergonomic design objectives which are largely different in their nature. In fact, the problem of seeking an ergonomically sound panel design should be viewed as a multiple objective optimization problem. Furthermore, most of the design objectives should be understood as constraints rather than objectives to be optimized. Hence, a constraint satisfaction approach is proposed in this study as a framework for the panel designer to search through the design decision space effectively and make various design decisions iteratively. In order to apply the constraint satisfaction approach to the panel design procedure, the ergonomic principles such as frequency-of-use, importance, functional grouping, and sequence-of-use are formalized as CSP terms. With this formalization, a prototype system was implemented and applied to panel layout problems. The results clearly showed the effectiveness of the proposed approach since it permits designers to consider and iteratively evaluate various design constraints and ergonomic principles, and, therefore, aids the panel designer to come up with an ergonomically sound control panel layout.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.18 no.2
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• pp.247-257
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• 2011

Purpose: This study was conducted to identify communication principles for nurses in cancer units according to Grice's theory. Method: This study was a secondary analysis of qualitative research using conversational analysis. Results: The principles consisted of four maxims: Quality, quantity, relevance and manner and 14 strategies. For the quality maxim, 'asking what you believe to be true' and 'saying the facts you know' strategies were identified. In the quantity maxim, the strategies were 'asking single questions', 'asking open questions' and 'asking optimistic questions'. In the relevance maxim, 'asking about the same theme' and 'giving relevant explanations' strategies were identified. In manner maxim, the strategies were 'using clear expressions in asking questions', 'asking in an orderly way', 'verifying answers', 'using clear expressions in explanations', 'explaining in an orderly way' and 'verifying understanding'. Conclusion: It is expected that these strategies will help and increase the degree of cooperation for nurses in effectively communication with cancer patients.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.3
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• pp.115-121
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• 2001

In micro automation technology, the concurrent realization of a high resolution and a large operating rage has been achieved by a dual actuator, usually called by piggy-back system, conventionally. But, because of its manufacturing cost, the complexity of control, and the limit of overall bandwidth, the contract-free and single servo actuators have been suggested with specific applications. In this paper, we suggest a novel non-contact surface actuator suing combination of the Lorentz force and the magnetized force, and discuss the actuating principles including an analytical approach. Differently from the existing planar system, an operating range of the suggested system can be expanded by an additional attachment of active elements. Therefore, it is estimated to be suitable for the next-generation moving system.

• Interaction and multiscale mechanics
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• v.1 no.3
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• pp.329-337
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• 2008

This paper presents the derivation of the generalized governing equations in theory of elasticity, their weak forms and the some applications in the numerical analysis of structural mechanics. Unlike the differential equations in classical elasticity theory, the generalized equations of the equilibrium and compatibility equations presented here take the form of integral equations, and the generalized equilibrium equations contain the classical differential equations and the boundary conditions in a single equation. By using appropriate test functions, the weak forms of these generalized governing equations can be established. It can be shown that various variational principles in structural analysis are merely the special cases of these weak forms of generalized governing equations in elasticity. The present weak forms of elasticity equations extend greatly the choices of the trial functions for approximate solutions in the numerical analysis of various engineering problems. Therefore, the weak forms of generalized governing equations in elasticity provide a powerful modeling tool in the computational structural mechanics.