• 감성과학
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• 제25권2호
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• pp.11-22
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• 2022

사회적인 존재로서 우리는 다른 사람의 행위를 빠르고 정확히 이해할 필요가 있다. 행위 이해는 여러 수준에서 일어난다. 무심코 타인의 의도를 알아챌 때가 있는가 하면, 그들의 목적을 추론하기 위해 노력해야만 하는 경우도 있다. 결합 사이먼 효과는 과제를 분업하는 한 쌍의 참가자가 의도치 않게 동료의 행위를 표상할 수 있음을 실험적으로 증명한다. 이 효과는 거의 자동적으로 발생한다고 알려졌지만, 인지부하의 영향을 받지 않을 만큼 자동적인지는 확인되지 않았다. 이에 본 연구는 참가자에게 작업기억 부하가 있거나 없는 상태에서 결합 사이먼 과제를 수행하게 하였다. 이중과제 구획에서 저부하 집단의 참가자들은 한 개의 숫자를 작업기억에 유지한 채로 사이먼 과제를 분업하였고, 고부하 집단의 참가자들은 다섯 개의 숫자를 유지한 채로 사이먼 과제를 분업하였다. 작업기억 부하의 효과를 분석하기 위해 이중과제 구획과 단일과제 구획의 집단별 사이먼 효과를 비교하였다. 반응시간을 분석한 결과, 저부하 집단은 이중과제와 단일과제 구획에서 모두 사이먼 효과를 보였지만, 고부하 집단은 어느 과제 구획에서도 사이먼 효과를 보이지 않았다. 이 결과는 결합 사이먼 효과가 인지 자원에 의존한다는 면에서 자동적인 현상을 아님을 의미한다. 즉, 분업 참여자는 인지적 자원이 가용한 경우에만 동료의 행위를 과제 표상에 반영하는 것으로 보인다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권2호
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• pp.600-616
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• 2021

SIMON and SPECK are two families of lightweight block ciphers that have excellent performance on hardware and software platforms. At CRYPTO 2019, Gohr first introduces the differential cryptanalysis based deep learning on round-reduced SPECK32/64, and finally reduces the remaining security of 11-round SPECK32/64 to roughly 38 bits. In this paper, we are committed to evaluating the safety of SIMON cipher under the neural differential cryptanalysis. We firstly prove theoretically that SIMON is a non-Markov cipher, which means that the results based on conventional differential cryptanalysis may be inaccurate. Then we train a residual neural network to get the 7-, 8-, 9-round neural distinguishers for SIMON32/64. To prove the effectiveness for our distinguishers, we perform the distinguishing attack and key-recovery attack against 15-round SIMON32/64. The results show that the real ciphertexts can be distinguished from random ciphertexts with a probability close to 1 only by 2^8.7 chosen-plaintext pairs. For the key-recovery attack, the correct key was recovered with a success rate of 23%, and the data complexity and computation complexity are as low as 2⁸ and 2^20.1 respectively. All the results are better than the existing literature. Furthermore, we briefly discussed the effect of different residual network structures on the training results of neural distinguishers. It is hoped that our findings will provide some reference for future research.

• BMB Reports
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• 제37권2호
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• pp.260-267
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• 2004

Transducin (T), the heterotrimeric guanine nucleotide binding protein in rod outer segments, serves as an intermediary between the receptor protein, rhodopsin, and the effector protein, cGMP phosphodiesterase. Labeling of T with dansyl chloride (DnsCl) inhibited its light-dependent guanine nucleotide binding activity. Conversely, DnsCl had no effect on the functionality of rhodopsin. Approximately 2-3 mol of DnsCl were incorporated per mole of T. Since fluoroaluminate was capable of activating DnsCl-modified T, this lysine-specific labeling compound did not affect the guanine nucleotide-binding pocket of T. However, the labeling of T with DnsCl hindered its binding to photoexcited rhodopsin, as shown by sedimentation experiments. Additionally, rhodopsin completely protected against the DnsCl inactivation of T. These results demonstrated the existence of functional lysines on T that are located in the proximity of the interaction site with the photoreceptor protein.

• 전자공학회논문지
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• 제50권9호
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• pp.179-185
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• 2013

본 논문에서는 시각에 대해 반응하는 운동 행동의 효과를 분석하기 위해서 응답속도정합-유발전위(RTA-ERP: Response Time Aligned-Event Related Potential)를 모델링하고, RTA-ERP의 진폭과 응답 속도를 이용하여 사이먼 효과를 분석하였다. 건강한 성인 15명(남성 9명, 여성 6명, 평균 연령 31세)을 대상으로, 같은 숫자에 대한 다른 숫자를 찾아 반응하는 '양자극방안' 실험을 7분 동안 수행하였다. 실험결과 제안된 RTA-ERP는 기존의 ERP에 비해 뇌에서의 처리시간 차이에 따른 변이를 보상할 수 있었으며, 향상된 LRP(Lateralized Readiness Potential)와 Pe(Error Related Positivity)를 나타내었다. '일치', '불일치' 시험 패턴에 대하여 '일치'에 대한 RTA-ERP의 진폭과 응답속도는 각각 '불일치'보다 컸으며 진폭은 $0.03{\mu}V$ 크고 반응속도는 43 ms 만큼 빨랐다. 응답속도에 따른 동기 시점을 보정하여 정합함에 따라, RTA-ERP의 진폭특성은 사이먼 효과의 특징인 ERP의 P300 진폭과 대응함을 확인하였다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2005년도 학술발표회(1)
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• pp.182-183
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• 2005

• 응용통계연구
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• 제27권7호
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• pp.1115-1123
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• 2014

제 1상 임상시험의 주목적은 시험약의 독성을 평가하여 부작용을 최소화하고 안전하게 투여할 수 있는 적정 용량인 최대허용용량(Maximum Tolerated Dose; MTD)의 추정이다. 기존에 최대허용용량 추정 방법에는 SM방법(Storer, 1989; Korn 등, 1994), ATD방법(Simon 등, 1997) 그리고 DM방법(Dixon과 Mood, 1948) 등이 있다. 본 논문에서는 초기 가속 단계를 적용하여 약효가 없는 낮은 용량에 많은 피험자들이 배정되는 점을 보완하고, 이 초기 가속 단계로 빠르게 용량을 증가함으로 인해 떨어진 안전성을 개선하기 위해 용량감량을 허용하는 방법을 적용시켜 MTD 를 추정하는 방법을 제안하였다. 기존의 방법들과 본 논문에서 제안한 방법을 모의실험을 통해 비교하였다.

• International Journal of Computer Science & Network Security
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• 제21권12spc호
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• pp.495-502
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• 2021

The study is devoted to substantiation of directions of intensification of development of small innovative enterprise, which has a significant impact on the overall innovation activity of the country and promotes innovative development, transition to more advanced technological systems. The outlined role of small business in innovative development in the direction of intensifying innovation in the economy, improving organization and production, as well as in the form of direct participation in the innovation process, production of science-intensive products, stimulating demand for innovation. A group of factors hindering the development of small innovative entrepreneurship was identified, including: financial aspects of the activity, shortcomings of organizational and communicative nature, underdeveloped technology market, information plan problems, internal production problems of small business, market problems. The directions of intensification of the development of small innovative entrepreneurship are substantiated, namely: financial and credit support of small innovative entrepreneurship; introduction of tax incentives; material and technical support; nationwide intensification of innovation activity; information support; development of innovation infrastructure. The involvement of the outlined directions of intensification of small innovative entrepreneurship will help to obtain a synergistic effect of innovative development of both small innovative business structures and the economy as a whole.

• 한국환경성돌연변이발암원학회지
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• 제22권4호
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• pp.255-258
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• 2002

In order to determine the safety of chemicals and pharmaceutical products, various methods can be used to evaluate the toxicity. In this study the genotoxic effect of the widely used industrial chemical, cadmium chloride, was assessed using the micronucleus test in peripheral blood of mice. The presence of micronucleated reticulocytes by microscopic observation following acridine orange staining indicated a potential genotoxic effect. The genotoxicity of intraperitoneally (i.p.) administered cadmium chloride (0.5, 1, 2 mg/kg) appeared to be dose dependent, with the maximum tolerated dose (MTD) found to be 2 mg/kg. Compared to the negative control (saline), cadmium chloride (2 mg/kg) exhibited statistically significant genotoxic potential (P<0.05) but was found to be less than the positive control of mitomycin C (0.5 mg/kg) and was not statistically significant compared to historical negative controls (P>0.05).

• Wind and Structures
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• 제19권2호
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• pp.185-197
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• 2014

Ventilation and fire safety design in road tunnels are one of the most complex issues that need to be carefully considered and analysed in the designing stage of any potential upgrade of ventilation and other fire safety systems in tunnels. Placement road tunnels space has an important influence on fire safety, especially when considering the effect of adverse wind conditions that significantly influence ventilation characteristics. The appropriate analysis of fire and smoke control is almost impossible without the use of modern simulation tools (e.g., CFD) due to a large number of influential parameters and consequently extensive data. The impact of the strong wind is briefly presented in this paper in the case of a longitudinally ventilated road tunnel Kastelec, which is exposed to various severe wind conditions that significantly influence its fire safety. The possibility of using CFD simulations in the analysis of the tunnel placement in space terms negative effect of wind influence on the tunnel ventilation is clearly indicated.

• Journal of Contemporary Eastern Asia
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• 제15권2호
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• pp.177-190
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• 2016

One of the main objectives of this paper is to provide insight to understand the effect of natural disasters on local government finance. That is, to analyze local governments' sales tax revenues after Hurricane Ike. Three Texas cities are examined: League City, Pearland, and Sugarland. Based on data collected from the Texas Comptroller's Office and the US Census, we found local governments experience a short-term increase in sales tax revenues and a long-term decline after the hurricane strike the region. On average, a major hurricane has a two-year impact on local government economy. The findings are essential for practitioners because in order to have a prosperous recovery after natural disasters, public managers have to prepare financially for short term changes in their sales tax revenues.