• Science of Emotion and Sensibility
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• v.25 no.2
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• pp.11-22
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• 2022

As social beings, we need to understand others' actions as quickly and accurately as possible. Action understanding can occur at many levels. We sometimes grasp others' intentions unintentionally. Other times, however, we have to expend effort to draw inferences about their goals. In the context of joint action, the joint Simon effect demonstrates that actors are influenced by the unintended representation of a co-actor's actions. This effect has been described as quasi-automatic, but it is unclear if the effect is automatic enough to be immune to cognitive load. Thus, we asked participants to complete a joint Simon task with or without a concurrent working memory task. One group of participants maintained a single digit in their mind during working memory load blocks (low-load group), while the other group maintained five digits (high-load group). As a result, the low-load group showed a joint Simon effect both during no-load and low-load blocks. In contrast, the high-load group had no joint Simon effect during either no-load or high-load blocks. These results suggest that the joint Simon effect is not an automatic phenomenon given that it requires cognitive resources. Actors in a joint task may represent a co-actor's actions in their task set, but only when cognitive resources are available.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.2
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• pp.600-616
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• 2021

SIMON and SPECK are two families of lightweight block ciphers that have excellent performance on hardware and software platforms. At CRYPTO 2019, Gohr first introduces the differential cryptanalysis based deep learning on round-reduced SPECK32/64, and finally reduces the remaining security of 11-round SPECK32/64 to roughly 38 bits. In this paper, we are committed to evaluating the safety of SIMON cipher under the neural differential cryptanalysis. We firstly prove theoretically that SIMON is a non-Markov cipher, which means that the results based on conventional differential cryptanalysis may be inaccurate. Then we train a residual neural network to get the 7-, 8-, 9-round neural distinguishers for SIMON32/64. To prove the effectiveness for our distinguishers, we perform the distinguishing attack and key-recovery attack against 15-round SIMON32/64. The results show that the real ciphertexts can be distinguished from random ciphertexts with a probability close to 1 only by 2^8.7 chosen-plaintext pairs. For the key-recovery attack, the correct key was recovered with a success rate of 23%, and the data complexity and computation complexity are as low as 2⁸ and 2^20.1 respectively. All the results are better than the existing literature. Furthermore, we briefly discussed the effect of different residual network structures on the training results of neural distinguishers. It is hoped that our findings will provide some reference for future research.

• BMB Reports
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• v.37 no.2
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• pp.260-267
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• 2004

Transducin (T), the heterotrimeric guanine nucleotide binding protein in rod outer segments, serves as an intermediary between the receptor protein, rhodopsin, and the effector protein, cGMP phosphodiesterase. Labeling of T with dansyl chloride (DnsCl) inhibited its light-dependent guanine nucleotide binding activity. Conversely, DnsCl had no effect on the functionality of rhodopsin. Approximately 2-3 mol of DnsCl were incorporated per mole of T. Since fluoroaluminate was capable of activating DnsCl-modified T, this lysine-specific labeling compound did not affect the guanine nucleotide-binding pocket of T. However, the labeling of T with DnsCl hindered its binding to photoexcited rhodopsin, as shown by sedimentation experiments. Additionally, rhodopsin completely protected against the DnsCl inactivation of T. These results demonstrated the existence of functional lysines on T that are located in the proximity of the interaction site with the photoreceptor protein.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.9
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• pp.179-185
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• 2013

In this paper, the RTA-ERP(Response Time Aligned-Evoked Relative Potential) was modelled to analyze the effect of motor activation pattern in response to visual sensory stimuli. Simon effect was analysed using the amplitude response of RTA-ERP and measured response time. The 'odd number' experiments, which identify an odd number mixed with same numbers, was performed with 15 healthy adult participants(9 males and 6 females, whose mean age of 31) for 7 minutes for each participant. Throughout experimentation, we observed that the proposed RTA-ERP can compensate the timing variation due to different neural processing procedures in the brain, and shows enhanced LRP(Lateralized Readiness Potential) and Pe(Error Related Positivity). Regarding to 'congruence' and 'incongruence' testing patterns, the amplitude of RTA-ERP and the response time for the 'congruence' are $0.03{\mu}V$ larger, and 43 ms faster than those for the 'incongruence', respectively. The amplitude characteristics of RTA-ERP, obtained by synchronizing the onset times with respect to response time, corresponds more likely to that of P300 in the ERP pattern (the characteristics of the Simon effect).

• Proceedings of the Korea Water Resources Association Conference
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• 2005.09a
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• pp.182-183
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• 2005

• The Korean Journal of Applied Statistics
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• v.27 no.7
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• pp.1115-1123
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• 2014

The main purpose of phase I clinical trials is to estimate the Maximum Tolerated Dose (MTD), which minimizes side effect and assures safety of a new drug by evaluating the toxicity at each dose-level. The conventional MTD estimation methods is Standard method (Storer, 1989; Korn et al., 1994), Accelerated Titration Designs (Simon et al., 1997) and DM method (Dixon and Mood, 1948) etc. In this paper, MTD estimation method with de-escalation is suggested phase I clinical trials. The proposed MTD estimation method is compared to Accelerated Titration Designs, SM3 without de-escalation method and SM3 with de-escalation method using a Monte Carlo simulation.

• International Journal of Computer Science & Network Security
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• v.21 no.12spc
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• pp.495-502
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• 2021

The study is devoted to substantiation of directions of intensification of development of small innovative enterprise, which has a significant impact on the overall innovation activity of the country and promotes innovative development, transition to more advanced technological systems. The outlined role of small business in innovative development in the direction of intensifying innovation in the economy, improving organization and production, as well as in the form of direct participation in the innovation process, production of science-intensive products, stimulating demand for innovation. A group of factors hindering the development of small innovative entrepreneurship was identified, including: financial aspects of the activity, shortcomings of organizational and communicative nature, underdeveloped technology market, information plan problems, internal production problems of small business, market problems. The directions of intensification of the development of small innovative entrepreneurship are substantiated, namely: financial and credit support of small innovative entrepreneurship; introduction of tax incentives; material and technical support; nationwide intensification of innovation activity; information support; development of innovation infrastructure. The involvement of the outlined directions of intensification of small innovative entrepreneurship will help to obtain a synergistic effect of innovative development of both small innovative business structures and the economy as a whole.

• Environmental Mutagens and Carcinogens
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• v.22 no.4
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• pp.255-258
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• 2002

In order to determine the safety of chemicals and pharmaceutical products, various methods can be used to evaluate the toxicity. In this study the genotoxic effect of the widely used industrial chemical, cadmium chloride, was assessed using the micronucleus test in peripheral blood of mice. The presence of micronucleated reticulocytes by microscopic observation following acridine orange staining indicated a potential genotoxic effect. The genotoxicity of intraperitoneally (i.p.) administered cadmium chloride (0.5, 1, 2 mg/kg) appeared to be dose dependent, with the maximum tolerated dose (MTD) found to be 2 mg/kg. Compared to the negative control (saline), cadmium chloride (2 mg/kg) exhibited statistically significant genotoxic potential (P<0.05) but was found to be less than the positive control of mitomycin C (0.5 mg/kg) and was not statistically significant compared to historical negative controls (P>0.05).

• Wind and Structures
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• v.19 no.2
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• pp.185-197
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• 2014

Ventilation and fire safety design in road tunnels are one of the most complex issues that need to be carefully considered and analysed in the designing stage of any potential upgrade of ventilation and other fire safety systems in tunnels. Placement road tunnels space has an important influence on fire safety, especially when considering the effect of adverse wind conditions that significantly influence ventilation characteristics. The appropriate analysis of fire and smoke control is almost impossible without the use of modern simulation tools (e.g., CFD) due to a large number of influential parameters and consequently extensive data. The impact of the strong wind is briefly presented in this paper in the case of a longitudinally ventilated road tunnel Kastelec, which is exposed to various severe wind conditions that significantly influence its fire safety. The possibility of using CFD simulations in the analysis of the tunnel placement in space terms negative effect of wind influence on the tunnel ventilation is clearly indicated.

• Journal of Contemporary Eastern Asia
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• v.15 no.2
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• pp.177-190
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• 2016

One of the main objectives of this paper is to provide insight to understand the effect of natural disasters on local government finance. That is, to analyze local governments' sales tax revenues after Hurricane Ike. Three Texas cities are examined: League City, Pearland, and Sugarland. Based on data collected from the Texas Comptroller's Office and the US Census, we found local governments experience a short-term increase in sales tax revenues and a long-term decline after the hurricane strike the region. On average, a major hurricane has a two-year impact on local government economy. The findings are essential for practitioners because in order to have a prosperous recovery after natural disasters, public managers have to prepare financially for short term changes in their sales tax revenues.