• BMB Reports
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• 제35권5호
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• pp.513-517
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• 2002

We describe a new method for identifying the sequences that signal the start of translation, and the boundaries between exons and introns (donor and acceptor sites) in human mRNA. According to the mandatory keyword, ORGANISM, and feature key, CDS, a large set of standard data for each signal site was extracted from the ASCII flat file, gbpri.seq, in the GenBank release 108.0. This was used to generate the scoring matrices, which summarize the sequence information for each signal site. The scoring matrices take into account the independent nucleotide frequencies between adjacent bases in each position within the signal site regions, and the relative weight on each nucleotide in proportion to their probabilities in the known signal sites. Using a scoring scheme that is based on the nucleotide scoring matrices, the method has great sensitivity and specificity when used to locate signals in uncharacterized human genomic DNA. These matrices are especially effective at distinguishing true and false sites.

• 건축역사연구
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• 제15권5호
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• pp.41-56
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• 2006

Signal fire was a communication system which deliver urgent news by smoke and light. It informed the condition of the border to the central government and the military base rapidly. This research was to analyze the border signal-fire which is the main facility of military protective duty for safety of sea side in chosun dynasty. The results of this research were described separately as follows. 1. The border signal-fire has three types of facility layout, The majority was one-site, near two-site, separate type. The majority was near two-site type. 2. Plan configuration of signal-fire stand which is separated with circle, oval, round-rectangular and rectangular type roughly was constructed with circle type generally. Four types of signal-fire stand was observed in southern and western sea side impartially. However, in eastern side, circle type of signal-fire stand was mainly found. Therefore, regional characteristics could be considered partially. 3. The height of signal-fire stand was about 8~10m. The diameter of combustion chamber on the signal-fire stand was 2~3m in circle type, and the dimension of rectangular type was about $1.9{\times}1.9{\sim}3.2{\times}3.0m$. 4. Building base that protect ground moisture and infilteration of rainfall was found in 10 border singal-fire, the height of it was about 0.3m~2.5m.

• 한국정보과학회논문지:소프트웨어및응용
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• 제34권7호
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• pp.595-602
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• 2007

본 논문에서는 미지의 아미노산 서열이 신호 펩티다제 I에 의해 절단되는 분비성 단백질인지를 판별하고, 분비성 단백질일 경우에는 절단 위치를 예측하는 방법을 제안한다. 아미노산의 소수성을 이용한 전처리를 수행하여 분비성 단백질의 선도서열인 신호서열의 존재와 절단 위치를 추정한다. 전처리를 통해서 신호서열 아닌 서열을 초기에 제외함으로써 신호서열 예측의 정확도를 높인다. 지지벡터기계를 신호서열의 예측에 효과적으로 적용하기 위해서, 생물학적 정보와 관련된 아미노산 서열간의 거리를 제안한다. 아미노산의 세포내 위치를 예측할 수 있는 소수성 척도와 아미노산의 진화적인 관계를 나타낼 수 있는 치환행렬을 이용하여 아미노산 서열간의 거리를 정의한다. Swiss-Prot release 50 단백질 자료에 대하여 교차타당성 기법을 사용하여 실험한 결과 제안한 방법은 신호서열중에 98.9%를 신호서열로 판별하였고, 88%의 절단위치 예측정확도를 보였다. 기존의 방법과의 비교실험을 통해서 제안한 방법이 신호서열의 예측에 더욱 효과적임을 확인하였다.

• 미생물학회지
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• 제24권3호
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• pp.236-242
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• 1986

The nucleotide sequence of the genetic control site of Bacillus subtilis gene for $(1-4)-{\beta}-D-glucan$ endoglucanase (cellulase) was determined according to the procedures of the dideoxy chain termination method(Sanger et. al., 1977). The deduced amino acid sequence of this enzyme has a hydrophobic signal peptide at the $NH_2$ terminus similar to those found in fifteen other extracellualr enzymes from Bacillus species. This is followed by a sequence resembling the Bacillus ribosome binding site 14 nucleotide before the first codon of the gene. The presumptive promoter sequence was located 92 base pairs upstream fromthe initiation codon. The homology region in signal sequences was striking when comparing all the signal sequences of sixteen extracellular enzymes from Bacillus species so far compiled.

• 한국항행학회논문지
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• 제23권2호
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• pp.142-150
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• 2019

포구속도는 총포탄약의 평가에 있어 가장 중요한 계측항목들 중 하나이다. 포구속도는 포탄이 포구를 떠나는 시점의 속도로 정의된다. 특히, 포구속도는 추진제의 성능과 밀접하게 관련이 있기 때문에 정확한 측정이 요구된다. 포구속도의 측정에는 도플러 레이더가 사용되나, 도플러 레이더 신호의 품질은 시험장 환경에 의존한다. 따라서 본 논문에서는 도플러 레이더의 신호 품질을 악화시키는 클러터를 시험장 구조 및 신호처리 방법의 개선을 통해 제거하는 방법을 제시하였다. 개선된 신호처리 방법의 적용을 위해 도플러 레이더의 원시 도플러 데이터를 획득하는 프로그램을 작성하였다. 시험장 구조 및 신호처리 방법의 개선을 통해 얻어진 속도 데이터에 대한 통계적인 검증으로 제안하는 방법이 기존에 사용하던 방법에 비해 클러터 제거에 효과가 있음을 증명하였다.

• 한국약용작물학회지
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• 제12권6호
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• pp.515-518
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• 2004

약용식물로 재배되고 있는 지모를 대상으로 McFISH 기법을 이용하여 45S와 5S rDNA 유전자의 염색체상의 위치를 확인하여 물리지도를 확립하였다. 2쌍의 45S rDNA는 1번 염색체의 단완 말단과 3번 염색체의 동원체 부위에서 관찰되었고, 1번 염색체의 signal이 3번 염색체에서의 signal보다 더 강하게 나타났다. 한 쌍의 5S rDNA signal은 45S rDNA signal과 함께 3번 염색체의 동원체 부위에서 관찰되었다.

• 미생물학회지
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• 제26권2호
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• pp.101-105
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• 1988

6M-MuLV mutants containing deldtions around the putative packaging signal were constructed by using recombinant DNA technique and transfected into NIH/3T3 cell. 2 of 6 mutants can not be packaged into virions even in the presence of the wild type helper virus. The boundary between the packagible and the non-packagible genome is located around Pvu I site, 421 nucleotide downstream from the 5' end of M-MuLV genome. 10 base pair inverted repeat sequence (GAGUCCAAAA) which can make stem structure around Pvu Isite could be the putative packaging signal.

• Journal of information and communication convergence engineering
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• 제13권3호
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• pp.167-171
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• 2015

A radio over fiber (RoF) system is a kind of analog optical transmission system and considered as a strong candidate for the next-generation fronthaul link in the future mobile network. In RoF systems, nonlinearity compensation is essential to increase the link capacity. In this paper, we propose a nonlinearity detection and compensation scheme using a monitoring channel in RoF systems. A monitoring channel is added at the transmitter site and used for transmitting a reference signal in an RoF transmission. The nonlinearity in the RoF transmission is detected by comparing the received monitoring signal and the original reference signal at the receiver site. Finally, the nonlinearity is compensated at the receiver by giving the reverse function of the detected nonlinearity. Our results show that the proposed scheme can almost remove the error vector magnitude degradation induced by the nonlinearity in the RoF system.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.311.1-311.1
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• 2002

Crystal structure of TRAF6 in complex with TRAF6-binding sites from CD40 was previously determined. The structure revealed a distinct TRAF6-binding groove of CD40. the key structural determinant of interaction. The structural information leads to a proposed TRAF6-binding motif. This allows the identification of TRAF6-binding sequences in the hlRAK protein, whose functional requirement in IL-1 mediated signal transduction is further demonstrated using site-directed mutagenesis. The mutational in IL-1 mediated signal transduction is further dimonstrated using site-directed mutagenesis. The mutational effects of hlRAK on the down-stream NF-${\kappa}$ signaling shows the importance of the TRAF6 interface for signaling by IL-1.

• 한국시뮬레이션학회:학술대회논문집
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• 한국시뮬레이션학회 2001년도 The Seoul International Simulation Conference
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• pp.77-82
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• 2001

An intelligent road transport management system focused on microscopic, real-time traffic signal control is proposed. Referring to the development of those systems in Japan, extensive use of image traffic detectors observing the movement of vehicles inside intersections, and direct data exchange between the signal controllers of neighboring intersections are newly assumed. On site investigation of five intersections in Japan or in Malaysia shows the possibility of effective information provision and simple algorithm for solving heavy congestion, as well as easy installation.