• Journal of Sensor Science and Technology
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• v.9 no.2
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• pp.96-105
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• 2000

Fiber optic TR-EFPI(total reflected extrtinsic Fabry-Perot interferometric) sensor was developed to measure the strain of structures, such as building, bridge, aircraft, etc. It has been difficult to distinguish the increase and decrease of the strain from the conventional fiber optic EFPI sensor because their signals only have a sinusoidal wave pattern related to the change of strain. Also, the absolute strain could not be measured by the simple fiber optic EFPI sensor. In this study, in order to measure the magnitude of strain with the direction of strain, the fiber optic sensor was simply constructed with the total reflected EFPI sensor probe. This probe was manufactured with a single mode fiber and a mirror coated fiber in a silica glass capillary tube. The output signal of this fiber optic TR-EFPT sensor can give the information about the magnitude and the direction of strain. The loading-unloading test was performed by the universal testing machine with alluminum beam specimen to compare the strain from fiber optic TR-EFPI sensor with the value from electrical strain gauge. In the result of this experiment. the strain from fiber optic TR-EFPI sensor had a good agreement with the values from the electrical strain gauge.

• Biomedical Science Letters
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• v.18 no.2
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• pp.104-111
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• 2012

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases which degrade extracellular matrix (ECM) during embryogenesis, wound healing, and tissue remodeling. Dysregulation of MMP activity is also associated with various pathological inflammatory conditions. In this study, we examined the expression pattern of MMPs during PMA-induced differentiation of THP-1 monocytic cells into macrophages. We found that MMP1, MMP8, MMP3, MMP10, MMP12, MMP19, MMP9, and MMP7 were upregulated during differentiation whereas MMP2 remained unchanged. Expression of MMPs increased in a time-dependent manner; MMP1, MMP8, MMP3, MMP10, and MMP12 increased beginning at 60 hr post PMA treatment whereas MMP19, MMP9, and MMP7 increased beginning at 24 hr post PMA treatment. To identify signal transduction pathways involved in PMA-induced upregulation of MMPs, we treated PMA-differentiated THP-1 cells with specific inhibitors for PKC, MEK1, NF-${\kappa}B$, PI3K, p38 MAPK and PLC. We found that inhibition of the MEK1 pathway blocked PMA-induced upregulation of all MMPs to varying degrees except for MMP-2. In addition, expression of select MMPs was inhibited by PI3K, p38 MAPK and PLC inhibitors. In conclusion, we show that of the MMPs examined, most MMPs were up-regulated during differentiation of monocyte into macrophage via the MEK1 pathway. These results provide basic information for studying MMPs expression during macrophage differentiation.

• The Journal of Internal Korean Medicine
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• v.21 no.2
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• pp.259-266
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• 2000

Objectives : The effects of aqueous extracts of Cortex ulmi pumilae (a traditional medicine for cancer treatment in oriental medicine) on the induction of apoptotic cell death were investigated in human liver origm hepatoma cell lines, HepG2. Methods : The death of HepG2 cells was markedly induced by the addition of extracts of Cortex ulmi pumilae in a dose-dependent manner. The apoptotic characteristic ladder pattern of DNA strand break was not observed in cell death of HepG2. In addition, it was not shown nucleus chromatin condensation and fragmentation under hoechst staining. However, by the using annexin V staining assay, externalizations of phosphatidylserine in HepG2 cell which were treated with Cortex ulmi pumilae extracts were detected in the early time (at 9 hr after extract treatment). Furthermore, LDH release was not detected in this early stage. Therefore, Cortex ulmi pumilae extracts-induced cell death of HepG2 cells is mediated by apoptotic death signal processes. Result : The activity of caspase 3-like proteases remained in a basal level in HepG2 cells which treated with the extract of Cordyceps sinensis. However, it was markedly increased in HepG2 cells which treated with two extracts of Cortex ulmi pumilae (C.U.P.-C, C.U.P.-K) which were differently extracted (respectively, 2.3 and 3.3 fold). On a while, the phosphotransferase activities of JNK1 was markedly induced in HepG2 cells which were treated with two extracts of Cortex ulmi pumilae. On the contrary, the activation of transcriptional activator, activating protein1(AP-1) and NF-kB were severely decreased by these two extracts of Cortex ulmi pumilae (C.U.P.-C, C.U.P.-K). In addition, antioxidants (GSH and NAC) and intracellular $Ca2^+$ level regulator (Bapta/AM and Thapsigargin) did not affect Cortex ulmi pumilae extracts-induced apoptotic death of HepG2 cells. Conclusions : In conclusion, our results suggest that two extracts of Cortex ulmi pumilae (C.U.P.-C, C.U.P.-K) induces the apoptotic death of human liver origin hepatoma HepG2 cells via activation of caspase 3-like proteases as well as JNK1, and inhibition of transcriptional activators, AP-1 and $NK-{\kappa}B$.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.158-162
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• 2009

Sound effects coming with appropriate tactile stimuli can strengthen its reality. For example, gunfire in games and movies, if it is accompanied by vibrating effects, can enhance the impressiveness. On a similar principle, adding the vibration information to existing sound data file and playing sound while generating vibration effects through haptic interfaces can augment the sound experience. In this paper, we propose a method to generate vibration information by analyzing the sound. The vibration information consists of vibration patterns and the timing within a sound file. Adding the vibration information is labor-intensive if it is done manually. We propose a sound detection algorithm to search the moments when specific sounds occur in a sound file and a method to create vibration effects at those moments. The sound detection algorithm compares the frequency characteristic of specific sounds and finds the moments which have similar frequency characteristic within a sound file. The detection ratio of the algorithm was 98% for five different kinds of gunfire. We also develop a GUI based vibrating pattern editor to easily perform the sound search and vibration generation.

• Journal of Astronomy and Space Sciences
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• v.24 no.4
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• pp.349-366
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• 2007

We designed and developed a multi-purpose CCD camera system for three kinds of CCDs; KAF-0401E($768{\times}512$), KAF-1602E($1536{\times}1024$), KAF-3200E($2184{\times}1472$) made by KODAK Co.. The system supports fast USB port as well as parallel port for data I/O and control signal. The packing is based on two stage circuit boards for size reduction and contains built-in filter wheel. Basic hardware components include clock pattern circuit, A/D conversion circuit, CCD data flow control circuit, and CCD temperature control unit. The CCD temperature can be controlled with accuracy of approximately $0.4^{\circ}C$ in the max. range of temperature, ${\Delta}33^{\circ}C$. This CCD camera system has with readout noise $6\;e^-$, and system gain $5\;e^-/ADU$. A total of 10 CCD camera systems were produced and our tests show that all of them show passable performance.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.5
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• pp.682-692
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• 2007

This study presents an automatic system to predict parturition time in the crated sows. The system relies on ultrasonic transducers mounted from above along the length of the crate. Using a 40 kHz time of flight (TOF) single envelope wave, the momentary distances between the sensors are measured. Therefore, the local momentary height of the sow and the momentary posture, i.e. standing posture (SDP), kneeling posture (KP), sitting posture (STP) and lateral lying posture (LLP) are determined. Crated sows change their postures from standing to lying and vice versa which follows a characteristic pattern. As parturition approaches, sows exhibit uneasiness, restlessness and the stand up sequence (SUS, the posture transition from LLP to SDP) rate increases because of labor pains. In time series, the SUS rate demonstrates a peak and it happens approximately 0-12 h before parturition. In this paper, the basic parturition threshold value method (BPTVM) and the same hour method (SHM) are proposed for predicting parturition, both of which are based on the SUS rate. The BPTVM mainly detects the peak of the SUS rate. As the SUS rate exceeds the threshold value, the parturition becomes predictable. Moreover, the SHM calculates the difference in the SUS rates between a particular time of day and the corresponding time of the preceding day. Compared to the BPTVM, the SHM can eliminate the circadian rhythm of the SUS rate influenced by feeding behavior. Using the SHM the parturition can be approximately predicted within hours. In an attempt to define the threshold parameters of predicting parturition, a data set with 32 sows of the SUS rate are used to estimate assumable predicting probability. The results show the assumable probability of the parturition prediction within 9 h is 96.9% for the SHM and 84.4% for the BPTVM. Moreover, the SHM can even reach a 75% probability of prediction within three hours of parturition. We conclude that the SHM is more accurate and is more useful for parturition time prediction. When parturition is detected, the proposed algorithm generates a warning signal which can inform human personnel to protect the mother and newborn piglets.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.16 no.2
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• pp.128-139
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• 2017

Railway is one of the public transportation systems along with shipping and aviation. With the recent introduction of high speed train, its proportion is increasing rapidly, which results in the higher risk of catastrophic failures. The wheel bearing to support the train is one of the important components requiring higher reliability and safety in this aspect. Recently, many studies have been made under the name of prognostics and health management (PHM), for the purpose of fault diagnosis and failure prognosis of the bearing under operation. Among them, the most important step is to extract a feature that represents the fault status properly and is useful for accurate remaining life prediction. However, the conventional features have shown some limitations that make them less useful since they fluctuate over time even after the signal de-noising or do not show a distinct pattern of degradation which lack the monotonic trend over the cycles. In this study, a new method for feature extraction is proposed based on the observation of relative frequency energy shifting over the cycles, which is then converted into the feature using the information entropy. In order to demonstrate the method, traditional and new features are generated and compared using the bearing data named FEMTO which was provided by the FEMTO-ST institute for IEEE 2012 PHM Data Challenge competition.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.12 no.3
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• pp.89-97
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• 2012

In recent years, efficient energy management technologies are required, as environmental problems have emerged worldwide. In response to this, smart home services focused on efficient energy management technology seems to be emerging. And the integration of technology of user-oriented real-time energy monitoring and control systems is required. In this paper, we present a location-based green home service using smart phones for efficient energy management in a house. We design a green home network system to apply the green home service, and implement an integrated gateway system which connects and controls each appliance in a house. We develop appliance control services and indoor location services on smart phones, and determine whether user's occupancy of each room by measuring the location according to the variation of signal strength. In order to evaluate the performance of the energy savings, we have set up the scenarios of energy usage pattern and have compared the energy variation resulting from the application of the indoor location services with smart meters. A comparison of energy usage demonstrated that the energy saving of a house with the proposed location-based green home service was down up to 30%.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.3B
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• pp.235-246
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• 2009

The number of industry wireless networks based on IEEE 802.11 WLAN technology deployed in large outdoor work sites, such as freight container terminal, is increasing these days. Wider service coverage, frequent movements of stations and high requirement on service reliability are main characteristics of these networks compared to the conventional IEEE 802.11 networks used in home, office and school. While the importance of these networks Bets higher, we can hardly find previous studies including concrete analysis on these networks based on actual experiments. We carried out several field experiments at a freight container terminal to analyze its IEEE 802.11 network and found out some problematic situations, such as over 50% retransmission rates and frequent disruption of communication link while a station is moving. We explain why these problematic situations happen and suggest some solutions, such as application of mesh technology, smart handoff based on location and movement pattern and adjustment of signal strength and channel allocation. Methods and tools used in the experiments are also detailed in the paper which may be helpful for similar future studies.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.46 no.5
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• pp.146-153
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• 2009

Recently, the research relative to NGN(Next Generation Network) is progressing in 3GPP(The 3rd Generation Partnership Progect), IETF(Internet Engineering Task Force), and so on. Although user needs frequently mobility which is various service pattern, In accordance with the development of these various applications, IMS(IP Multimedia Subsystem) and hierarchical networks ie, Femtocell/WiBro/3G etc is constructed for more user demands which provide service in anytime, anywhere. It is necessary to optimum network selection criterion which consider to wireless signal quality add to user service profile and service network traffic balance. NGN also needs a method to perform heterogeneous handover and to constraint Ping-pong phenomenon when using existing terminal-based handover decision. This paper proposes scheme for network selection and heterogeneous handover procedure in hierarchical wireless multi-access network based on SIP-MIH(Session Initiation Protocol-Media Independent Handover) with IMS by using user service profile that the considerations are dealing with not only selection and registration of various access network but also easy of developing the terminal.