• Transactions of the Korean Society of Mechanical Engineers A
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• v.41 no.10
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• pp.923-929
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• 2017

Generally, the sound emitted from a vehicle powered by an electric motor is lower than that of internal combustion engine vehicles. Therefore, pedestrians often cannot detect approaching electric vehicles. Therefore, a certain additional warning sound is required for these types of automobiles. In this study, to develop an audible warning sound, nine warning sounds are designed based on signal processing and chord theory. The background noise measured on the road is also added to these synthetic sounds. The detectability of these warning sounds is evaluated by subjective tests. The sound metric is correlated to detectability and is investigated through psychoacoustic theory and subjective evaluation. It is determined that known psychoacoustic parameters such as loudness, sharpness, and roughness have a low correlation with detectability. However, it is found that the interval of harmonic sound correlates well with detectability.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5113-5117
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• 2012

Prohibitin (PHB) is a chaperone protein which is highly conserved evolutionarily. It shows significant homology with the Drosophila cc gene which is considered important for development and differentiation of Drosophila melanogaster. Investigations have revealed an involvement of PHB in cellular proliferation and development, apoptosis, signal transduction, mitochondrial function and regulation of the estrogen and androgen receptors. Therefore, we conducted the present study to analyze mutations in the highly conserved region in Indian female breast cancer patients. Conventional PCR-SSCP and Automated DNA sequencing were performed with a total of 105 breast cancer samples along with adjacent normal tissue. Of the total, 14.2% (15/105) demonstrated a mutation status of prohibitin observed in our study population. We identified a novel missense mutation (Thr>Ser), a novel deletion of T nucleotide in an intron adjacent to intron-exon boundary and a previously determined missense mutation (Val>Ala). A statistically significant correlation was obtained which suggested that prohibitin may be associated with tumor development and/or progression of at least some proportion of breast cancers.

• Clinical and Experimental Pediatrics
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• v.61 no.3
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• pp.78-83
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• 2018

Purpose: Frequent desaturation due to immature incoordination of suck-swallow-breathing in preterm infants can influence multiple organs such as the heart, lungs, and brain, which can then affect growth and development. Most notably in preterm infants, feeding desaturation may even affect pulmonary function during gavage feeding. Because respiratory muscle activities may reflect the work required during respiration, we evaluated the differences in these activities between full-term and preterm infants with feeding desaturation, and investigated the correlations with clinical variables. Methods: Nineteen preterm infants with feeding desaturation (group 1) and 19 age-matched full-term infants (group 2) were evaluated. Oromotor function was evaluated using video recording. The root-mean-square (RMS) envelope of the electromyography signal was calculated to quantify the activities of muscles involved in respiration. The differences in RMS between both groups and the correlation with clinical variables including gestational age (GA), birth weight (BW), and Apgar scores (AS) at 1 and 5 minutes after birth were evaluated. Results: The RMS values of the diaphragm (RMS-D) and rectus abdominis (RMS-R) were significantly greater in group 1 compared to group 2, and the 1- and 5-min AS were significantly lower in group 1 compared to group 2. RMS-D and RMS-R were inversely correlated with GA, BW, 1- and 5-min AS in all infants. Conclusion: This study showed that respiratory muscle activities were augmented during feeding in preterm infants compared to full-term infants. Additionally, respiratory muscle activities were inversely correlated with all clinical variables.

• Journal of Broadcast Engineering
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• v.13 no.3
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• pp.328-338
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• 2008

Multi-view video coding (MVC) based on H.264/AVC encodes multiple views efficiently by using a prediction scheme that exploits inter-view correlation among multiple views. However, with the increase of the number of views and use of inter-view prediction among views, total encoding time will be increased in multiview video coding. In this paper, we propose a fast mode decision using both MB(Macroblock)-based region segmentation information corresponding to each view in multiple views and global disparity vector among views in order to reduce encoding time. The proposed method achieves on average 40% reduction of total encoding time with the objective video quality degradation of about 0.04 dB peak signal-to-noise ratio (PSNR) by using joint multi-view video model (JMVM) 4.0 that is the reference software of the multiview video coding standard.

• Journal of Broadcast Engineering
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• v.18 no.2
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• pp.311-318
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• 2013

This paper deals with a noise reduction algorithm which uses the binary masking in the time-frequency domain. To improve speech intelligibility in noise, noise-masked speech is decomposed into time-frequency units and mask "0" is assigned to masker-dominant region removing time-frequency units where noise is dominant compared to speech. In the previous research, Gaussian mixture models were used to classify the speech-dominant region and noise-dominant region which correspond to mask "1" and mask "0", respectively. In each frequency band, data were collected and trained to build the Gaussian mixture models and detection procedure is performed to the test data where each time-frequency unit belongs to speech-dominant region or noise-dominant region. In this paper, we consider the correlation of masks in the frequency domain and propose a post-processing method which exploits the Viterbi algorithm.

• Biomedical Science Letters
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• v.7 no.4
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• pp.167-172
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• 2001

Nebulin is an approximately 700 kDa filamentous protein in vertebrate skeletal muscle. It binds to the Z line and also binds side-by-side to the entire thin actin filament in a sarcomere. The correlation of nebulin size with thin filament length have led to the suggestion that nebulin acts as a molecular ruler for the length of thin filaments. The C-terminal part of human nebulin is anchored in the sarcomeric Z-disk and contains an SH3 domain. SH3 domains have been identified in an ever-increasing number of proteins important for a wide range of cellular processes, from signal transduction to cytoskeleton assembly and membrane localization. However, the exact physiological role of SH3 domains remains, in many cases, unclear. To explore the role of nebulin SH3 in the cytoskeletal rearrangement that accompanies myoblast differentiation, we transfected sense and antisense nebulin SH3 domain fused to enhanced green fluorescent protein in myoblast. Cells expressing nebulin SH3 fragment showed decrease of cell-cell adhesion, and cells transfected with antisense nebulin SH3 gene showed a rounded cell morphology and loss of cell-matrix adhesion. No alteration in cell shape and differentiation were observed in control cells expressing enhanced green fluorescent protein. Perturbation of nebulin altered the cell shape and disrupted cell adhesion in myoblast, demonstrating that nebulin can affect cytoskeleton rearrangement.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.7A
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• pp.794-806
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• 2004

This paper deals with correction of frequency offset and analysis of quantization angle noise in the IEEE 802.1la OFDM system. The rotation phase per symbol due to the carrier frequency offset is estimated from auto-correlation of the short Preambles, which are over-sampled for the reduction of noise in OFDM signals. The pilot signals are introduced to estimate the rotation phase per OFDM symbol due to estimation error of the carrier frequency offset and the sampling frequency onset. During the estimation and correction of the frequency onsets, a CORDIC processor and a look-up table are used for the conversion between a rotation phase and its complex number. Being calculated by a limited number of bits in the CORDIC processor and the look-up table, the rotation phase and its complex number have quantization angle errors. The quantization errors are analyzed as SNR (signal to noise ratio) due to the quantization bit numbers. The minimum bit number is suggested to meet the specification of IEEE 802.1la properly. Finally, the quantization errors are evaluated through simulations on number of quantization bits and SNR of received signals.

• The KIPS Transactions:PartB
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• v.13B no.3 s.106
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• pp.309-314
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• 2006

Recently, multimedia DBMS is appeared to be the core technology of the information society to store, manage and retrieve multimedia data efficiently. In this paper, we propose a new method for content based-retrieval system using wavelet transform, energy value to extract automatically feature vector from image data, and suggest an effective retrieval technique through this method. Wavelet transform is widely used in image compression and digital signal analysis, and its coefficient values reflect image feature very well. The correlation in wavelet domain between query image data and the stored data in database is used to calculate similarity. In order to assess the image retrieval performance, a set of hundreds images are run. The method using standard derivation and mean value used for feature vector extraction are compared with that of our method based on energy value. For the simulation results, our energy value method was more effective than the one using standard derivation and mean value.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.11A
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• pp.1078-1084
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• 2010

The tracking performance of a big parabola tracking antenna system for tracking and receiving of the signal from the vehicle is impacted by many factors of the internal and the external of the system. In this paper, we analyze the tracking error due to the radio refraction in the application of the tracking and positioning of the vehicle by using radio frequency. The real measurement data are used for the analysis which had been acquired by using GPS and the tracking systems of C- and S-band frequencies in NARO Space centre. To verify the correlation between the tracking errors measured and the radio refraction, we review the error factors and the accuracies of the tracking systems, and the characteristics of the refractivity. The analysis shows that there are angular errors which are due to the radio refraction and not to be neglected, compared to the accuracies of the tracking systems, in case of low elevation angle less than 10 degrees. Also, the tracking errors depend on the target altitude as well as the elevation angle for the case of the target in the troposphere. It is recommended to correct the tracking angle considering the target altitude and elevation angle for the precise target positioning.

• Journal of Biosystems Engineering
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• v.32 no.6
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• pp.440-447
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• 2007

In this study, a biosensor was developed using an enzyme-linked immunosorbent assay (ELISA) to rapidly measure the fungicide iprovalicarb residues in agricultural products. The biosensor was designed to include micro-pumps and solenoid valves for fluid transport, a spectrophotometer cuvet as a reaction chamber, a photodiode with a light-emitting diode for optical density measurement, and a control microcomputer to implement assay. The rate of change in optical density of the cuvet was read as final signal output. Micro-pumps were evaluated to investigate their delivery capability, the highest values of the error and the coefficient of variation were 4.3% and 4.6% respectively. As the incubation period was reduced from 15 minutes to 11 minutes to shorten the total processing time, the sensor sensitivity was decreased as the antibody dilution ratio was reduced to a half. The maximum usable period of the coated cuvet was found to be two days with 1% error limit. To predict the concentration of the iprovalicarb residue in agricultural products, a linear calibration model was obtained with r-square values of 0.992 for potato and 0.985 for onion. In validation test for the samples of potatoes and onions against the high performance liquid chromatography, very high correlation values were obtained as 0.996 and 0.993 respectively. Using the cuvet immobilized with antigen, it took 21-minutes for the biosensor to complete the measuring process of the iprovalicarb residues.