• 제목/요약/키워드: Side-effect

검색결과 5,236건 처리시간 0.038초

Stabilization of Poly(dA)·[poly(dT)]₂Triple Helical DNA by Acridine Derivatives: Role of Side Chain in the Triplex Stabilization

  • 현경미;이길준;조태섭;Kim, Seog K.;이세윤
    • Bulletin of the Korean Chemical Society
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    • 제18권5호
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    • pp.528-534
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    • 1997
  • The conformation and stabilization effects of acridine derivatives 9-aminoacridine, an acridine with an aminoalkyl side chain, bis acridine (two acridines linked by an aminoalkyl side chain), and proflavin in the triplex helical poly(dA)·[poly(dT)]2 were investigated by optical spectroscopies. Based on the negative LD and weak positive CD in the acridine absorption wavelength region, we concluded that the acridine moiety of all derivatives are intercalated. We also examined the melting temperatures. Of all the compounds examined, the acridine with an amino alkyl side chain had the strongest effect on the stabilization of the third strand of a poly (dA)·[poly(dT)]2 triplex. The role of the side chain, based on this observation, is discussed.

지역난방의 효율향상을 위한 수요관리 (Demand Side Management for Efficiency Enhancement of District Heating)

  • 김영일;강병하;최성호;김용열;김인택;전호철
    • 대한설비공학회:학술대회논문집
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    • 대한설비공학회 2006년도 하계학술발표대회 논문집
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    • pp.258-263
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    • 2006
  • In this study, demand side management for efficiency enhancement of district heating has been investigated. Objectives of demand side management of district heating are classified and analyzed. Foreign and domestic examples are studied. Evaluation methods of demand side management of district heating are studied. Applications and expected effect of the results are presented. Finally directions for demand side management of district heating efficiency enhancement are suggested.

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Transient thermo-mechanical response of a functionally graded beam under the effect of a moving heat source

  • Al-Huniti, Naser S.;Alahmad, Sami T.
    • Advances in materials Research
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    • 제6권1호
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    • pp.27-43
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    • 2017
  • The transient thermo-mechanical behavior of a simply-supported beam made of a functionally graded material (FGM) under the effect of a moving heat source is investigated. The FGM consists of a ceramic part (on the top), which is the hot side of the beam as the heat source motion takes place along this side, and a metal part (in the bottom), which is considered the cold side. Grading is in the transverse direction, with the properties being temperature-dependent. The main steps of the thermo-elastic modeling included deriving the partial differential equations for the temperatures and deflections in time and space, transforming them into ordinary differential equations using Laplace transformation, and finally using the inverse Laplace transformation to find the solutions. The effects of different parameters on the thermo-mechanical behavior of the beam are investigated, such as the convection coefficient and the heat source intensity and speed. The results show that temperatures, and hence the deflections and stresses increase with less heat convection from the beam surface, higher heat source intensity and low speeds.

The protective effects of trace elements against side effects induced by ionizing radiation

  • Hosseinimehr, Seyed Jalal
    • Radiation Oncology Journal
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    • 제33권2호
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    • pp.66-74
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    • 2015
  • Trace elements play crucial role in the maintenance of genome stability in the cells. Many endogenous defense enzymes are containing trace elements such as superoxide dismutase and metalloproteins. These enzymes are contributing in the detoxification of reactive oxidative species (ROS) induced by ionizing radiation in the cells. Zinc, copper, manganese, and selenium are main trace elements that have protective roles against radiation-induced DNA damages. Trace elements in the free salt forms have protective effect against cell toxicity induced by oxidative stress, metal-complex are more active in the attenuation of ROS particularly through superoxide dismutase mimetic activity. Manganese-complexes in protection of normal cell against radiation without any protective effect on cancer cells are more interesting compounds in this topic. The aim of this paper to review the role of trace elements in protection cells against genotoxicity and side effects induced by ionizing radiation.

DSM(Demand-Side Management)이 경쟁적인 전력시장에 미치는 영향 (The effect of DSM(Demand-Side Management) in competitive electricity market)

  • 김문영;백영식;김정훈;송경빈
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2000년도 하계학술대회 논문집 A
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    • pp.388-390
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    • 2000
  • The production of electricity and the pattern of consumption in competitive electricity market are changing. The price of electric power in spot market will be varied by the economic electricity availability of generation utilities and electricity consumers. DSM(demand-side management) is a method which provides simultaneously economics to utilities and consumers as main participants in electricity market. In this paper, it is argued that the effect of DSM in competitive electricity market for consumers, generation utilities, and transmission utilities.

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사이드 비어러 가 있는 보기 의 安定性 및 커브 走行性能 (Stability and Curving Performance of Bogies Having Side Bearer)

  • 임진수
    • 대한기계학회논문집
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    • 제8권6호
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    • pp.526-535
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    • 1984
  • 본 연구에서는 개인용 컴퓨터 정도를 사용하여서도 각 성능을 계산할 수 있고 또 실제 상황이 비교적 잘 반영될 수 있는 모델을 채택하였다. 한편으로 이 모델의 적합성 여부도 검토하여 해석 결과의 적용한계를 추측하고져 하였다.

Jet Flow Interactions in the Practical Airframe Design

  • Hong, Seung-Kyu;Lee, Kwang-Seop
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2006년도 추계 학술대회논문집
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    • pp.20-21
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    • 2006
  • Three kinds of jet flows encountered in the practical airframe design phase are discussed in this paper. Firstly, the side jet effect on the cavity flow over the flat plate was investigated. Secondly, the aerodynamic modeling of side jet influence on body-tail configuration was presented. Computational study of the similarity parameters was done to minimize the wind tunnel test. Lastly, supersonic jet impingement on a flat plate surrounded by solid walls was simulated numerically for both axi-symmetric and three-dimensional calculations with moving body method.

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페르체소자를 이용한 굴패각의 흡착 및 탈착촉진효과에 관한 연구 (Study on the Adsorption and Desorption Enhance Effect of Oyster Shell Using Peltier Element)

  • 김명준
    • 동력기계공학회지
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    • 제17권1호
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    • pp.71-76
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    • 2013
  • This study is experimentally performed for using the oyster shell as a desiccant in the batch type system. The peltier element(thermoelectric device) is used for absorbing and releasing the adsorption and desorption heat generation. The cooling and heating effects of peltier element exist in this experiment and these effects are generally known phenomena among some references. The increase in electric current induced into peltier element is effectively release the heat generation of adsorption and desorption. Consequently, the non-dimensional adsorption and desorption amount would increase with increase in electric current. However, in the case of adsorption, the increase of induced current into peltier element, the heat of cold side can not release sufficiently. So the heat of hot side of peltier is transferred into the cold side.

이면 수냉이 용접부 물성에 미치는 영향 (Effect of Water-Cooling of Opposite SIde Caused by the Welding of Hull Internal on Weld Properties)

  • 서창교;구연백;최승면
    • 대한용접접합학회:학술대회논문집
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    • 대한용접접합학회 2004년도 춘계 학술발표대회 개요집
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    • pp.203-205
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    • 2004
  • Welding sometimes should be done inside-hull after launching. The opposite side is contacted sea-water In this case, it should be a concern that the cooling rate expected very rapid may deteriorate microstructures, and hence these microstructures are hardened, cracking happens, or toughness would be impaired. Therefore, a test program simulating the situation has been planned and welded using the ship class materials (AH32, EH36) with the related welding consumables (E71Tl-1, E81Tl-K2) and then carried out to investigate the effect of cooling rate on weldments quality. Based on the test results, it could be concluded that the welds of which the opposite side of arc is exposed to wet or flowing water are not affected by rapid cooling.

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Effect of the corrosion of plate with double cracks in bonded composite repair

  • Berrahou, Mohamed;Salem, Mokadem;Mechab, B.;Bouiadjra, B. Bachir
    • Structural Engineering and Mechanics
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    • 제64권3호
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    • pp.323-328
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    • 2017
  • This paper presents a three-dimensional finite element method analysis of repairing plate with bonded composite patch subjected to tensile load. The effect of the corrosion on the damage of the adhesive (FM73) in the length of two horizontal cracks on the both sides is presented. The obtained results show that the crack on the left side creates a very extensive area of the damaged zone and gives values of the stress intensity factor (SIF) higher than that on the right side. We can conclude that the left crack is more harmful (dangerous) than that on the right side.