• Nutrition Research and Practice
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• v.18 no.1
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• pp.1-18
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• 2024

BACKGROUND/OBJECTIVES: Endoplasmic reticulum (ER) stress in adipose tissue causes an inflammatory response and leads to metabolic diseases. However, the association between vitamin D and adipose ER stress remains poorly understood. In this study, we investigated whether 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) alleviates ER stress in adipocytes. MATERIALS/METHODS: 3T3-L1 cells were treated with different concentrations (i.e., 10-100 nM) of 1,25(OH)₂D₃ after or during differentiation (i.e., on day 0-7, 3-7, or 7). They were then incubated with thapsigargin (TG, 500 nM) for an additional 24 h to induce ER stress. Next, we measured the mRNA and protein levels of genes involved in unfold protein response (UPR) and adipogenesis using real-time polymerase chain reaction and western blotting and quantified the secreted protein levels of pro-inflammatory cytokines. Finally, the mRNA levels of UPR pathway genes were measured in adipocytes transfected with siRNA-targeting Vdr. RESULTS: Treatment with 1,25(OH)₂D₃ during various stages of adipocyte differentiation significantly inhibited ER stress induced by TG. In fully differentiated 3T3-L1 adipocytes, 1,25(OH)₂D₃ treatment suppressed mRNA levels of Ddit3, sXbp1, and Atf4 and decreased the secretion of monocyte chemoattractant protein-1, interleukin-6, and tumor necrosis factor-α. However, downregulation of the mRNA levels of Ddit3, sXbp1, and Atf4 following 1,25(OH)₂D₃ administration was not observed in Vdr-knockdown adipocytes. In addition, exposure of 3T3-L1 preadipocytes to 1,25(OH)₂D₃ inhibited transcription of Ddit3, sXbp1, Atf4, Bip, and Atf6 and reduced the p-alpha subunit of translation initiation factor 2 (eIF2α)/eIF2α and p-protein kinase RNA-like ER kinase (PERK)/PERK protein ratios. Furthermore, 1,25(OH)₂D₃ treatment before adipocyte differentiation reduced adipogenesis and the mRNA levels of adipogenic genes. CONCLUSIONS: Our data suggest that 1,25(OH)₂D₃ prevents TG-induced ER stress and inflammatory responses in mature adipocytes by downregulating UPR signaling via binding with Vdr. In addition, the inhibition of adipogenesis by vitamin D may contribute to the reduction of ER stress in adipocytes.

• The Korean Journal of Malacology
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• v.30 no.1
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• pp.87-93
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• 2014

The Morphological characteristics of four species of Korean Abalone species, Nordotis discus hannai, N. discus discus, N. gigantea, N. madaka were compared. then Phenotypic traits were characterized. we collected from coast of samchonpo, sacjon-si, Gyeongsangnam-do and jeju-do of korea 69 individual of Nordotis discus hannai from 2013 December to 2014 January, 180 individual of N. discus, 72 individual of N. gigantea and 54 individual of N. madaka respectively then morphological traits of theses species characteristics were compared. The relationship between Shell length (SL), shell breth (SB), shell height (SH) and total weigh (TW) was expressed by the following equation: SB = 0.6346SL + 3.9082 ($R^2$ = 0.8956), SH = 0.2399SL + 3.2609 ($R^2$ = 0.8024), $TW=0.0009SL^{2.5622}$ ($R^2$ = 0.8088) in the Haliotis discus hannai, SB = 0.7249SL + 1.8035 ($R^2$ = 0.9634), SH = 0.3115SL - 11.223 ($R^2$ = 0.8593), $TW=0.0001SL^{2.9696}$ ($R^2$ = 0.8956) in the H. discus discus, SB = 0.7730SL - 1.1931 ($R^2$ = 0.933), SH = 0.2082SL + 3.2627 ($R^2$ = 0.6927), $TW=0.0002SL^{2.8330}$ ($R^2$ = 0.8431) in the Haliotis gigantea, SB = 0.7513SL - 1.0951 ($R^2$ = 0.913), SH = 0.2618SL - 6.1538 ($R^2$ = 0.6927), $TW=0.0001SL^{2.9614}$ ($R^2$ = 0.9353) in the Haliotis madaka.

• Korean Journal of Soil Science and Fertilizer
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• v.34 no.6
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• pp.407-412
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• 2001

This study was conducted to find out the effect of slow-release nitrogen fertilizer, such as latex coated urea(LCU) and Meister10(MS10) on direct seeded rice in dry soil(DS). Junghwabyeo, and early maturity rice cultivar was grown on the plots which were treated with None-nitrogen. urea. LCU and MS10 plot. Growth characteristic, yield and yield components were investigated. Nitrogen uptake-efficiency and physico-chemical properties of soil before-after experiment were analyzed. Plant height and number of tillers $m^{-2}$ in LCU and MS10 plot at early grow stages were higher than those in urea plot. Plant height and number of tillers $m^{-2}$ grown on the plot of Ms10 plot were higher than those of LCU plot. The number of seedling $m^{-2}$ were no significant differences among None-N, urea, and MS10 plot in DS. Heading date and leaf color were higher with Urea than LCU and MS10 plot. Culm length in LCU and MS10 plot were longer compared with urea plot, but panicle length was similar among with Urea, LCU and MS10 plot. Number of panicles $m^{-2}$ was greater in order of MS10 > LCU > Urea plot. Yield were greater in order of MS10 > LCU > Urea plot. Nitrogen uptake and nitrogen efficiency were greater in order of MS10 > LCU > urea plot. After the experiment, total content of nitrogen in soil was not changed at all treatments, but pH, P and Si of soil were lower than those of before experiment at all treatments.

• Proceedings of the Korea Water Resources Association Conference
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• 2006.05a
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• pp.1362-1366
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• 2006

우리나라에서는 하천법 제11조에 의거하여 10년마다 한 번씩 수자원장기종합계획을 수립하고 있으며, 필요에 따라 5년마다 이를 수정 보완하고 있다. 2001년 7월 수자원장기종합계획(Water Vision 2020)이 수립된 이후 잦은 봄 가뭄 등 이수측면에서의 사회, 경제, 환경의 변화와 최근 이상홍수 등으로 인한 대규모 홍수피해 발생에 따른 치수측면의 종합적인 대책의 제시가 요구되면서 2001년 수립된 계획에 대한 보완 필요성이 제기되었다. 또한 수자원계획의 신뢰성에 대한 시민단체 등의 문제제기와 지역 차원의 수자원계획 및 수자원환경에 대한 국민적 관심 증대로 인해 계획 수립 과정과 결과에 대한 국민적인 공감대 형성을 위한 체제의 구축이 금번 보완 계획의 수립을 통해 추진되고 있다. 금번 수자원장기종합계획 보완은 투명성 확보라는 큰 목표를 가지고 수행되고 있으며, 이를 통해 국가 수자원 관리의 청사진을 제시하고 물 수급 전망 및 용수수급 계획을 수립하는 과정에 있다. 기 개발된 한국형 통합수자원평가계획 모형인 K-WEAP 모형을 보완 계획 수립 과정에서 활용하고 있으며, K-WEAP 모형을 통해 물 수지 분석을 수행하여 수급 균형을 판단함으로써 일반 대중에게 물 수급 관련 상황에 대한 이해력을 높일 수 있다는 장점을 확보할 수 있다. 본 연구에서는 K-WEAP 모형을 이용하여 각 권역별로 2003년의 물 수급 현황을 분석하여 이를 하천의 관측유량과 비교해봄으로써 모형의 검증을 수행하였으며, 각 권역에서 시나리오별로 추정된 용수수요량을 이용하여 물 수지 분석을 수행함으로써 목표연도별 물 수급 분석결과를 제시하였다. 물 수급 분석 시 지하수 및 농업용 저수지 등 하천과 다목적댐 이외의 지역 공급원에 대해서도 고려하였으며, 이를 통해 수자원계획 수립 시 도움이 될 수 있는 기초적인 자료를 제공할 수 있었다. 인공순환에 의한 저감효과가 크지는 않을 것으로 예측된다. 조사 기간중 H호의 현존 식물플랑크톤량의 $60%{\sim}87%$가 수심 10m 이내에 분포하였고, 녹조강과 남조강이 우점하는 하절기에는 5m 이내에 주로 분포하였다. 취수탑 지점의 수심이 연중 $25{\sim}35m$를 유지하는 H호의 경우 간헐식 폭기장치를 가동하는 기간은 물론 그 외 기간에도 취수구의 심도를 표층 10m 이하로 유지 할 경우 전체 조류 유입량을 60% 이상 저감할 수 있을 것으로 조사되었다.심볼 및 색채 디자인 등의 작업이 수반되어야 하며, 이들을 고려한 인터넷용 GIS기본도를 신규 제작한다. 상습침수지구와 관련된 각종 GIS데이타와 각 기관이 보유하고 있는 공공정보 가운데 공간정보와 연계되어야 하는 자료를 인터넷 GIS를 이용하여 효율적으로 관리하기 위해서는 단계별 구축전략이 필요하다. 따라서 본 논문에서는 인터넷 GIS를 이용하여 상습침수구역관련 정보를 검색, 처리 및 분석할 수 있는 상습침수 구역 종합정보화 시스템을 구축토록 하였다.N, 항목에서 보 상류가 높게 나타났으나, 철거되지 않은 검전보나 안양대교보에 비해 그 차이가 크지 않은 것으로 나타났다.의 기상변화가 자발성 기흉 발생에 영향을 미친다고 추론할 수 있었다. 향후 본 연구에서 추론된 기상변화와 기흉 발생과의 인과관계를 확인하고 좀 더 구체화하기 위한 연구가 필요할 것이다.게 이루어질 수 있을 것으로 기대된다.는 초과수익률이 상승하지만, 이후로는 감소하므로, 반전거래전략을 활용하는 경우 주식투자기간은 24개월이하의 중단기가 적합함을 발견하였다. 이상의 행태적 측면과 투자성과측면의 실증결과를 통하여 한국주식시장에 있어서 시장수익률을 평균적으로 초과할 수 있는 거래전략은 존재하므로 이러한 전략을 개발 및 활용할 수 있으며, 특히, 한국주

• Journal of the Korean association of regional geographers
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• v.11 no.1
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• pp.29-39
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• 2005

Silk Road is the term involving all traffic roads connecting the East to the West, and ancient Korean culture has became globalized through Silk Road. In this paper, natural environment of Silk Road is considered as fundamental data in order to understand the Western culture introduced through Silk Road. Silk Road region is classified into Loess Plateau district; arid basin district; and high mountains district; Hesi Corridor(河西回廊) is the transition zone that the southeastern part of $W{\breve{u}}w{\bar{e}}i$(武威) is Loess Plateau district; other northwestern part is arid basin district Loess Plateau district, composed of homogeneous fines, has experienced dramatic soil loss by bringing under cultivation. At recent times, reforestation and construction of check-dam have been in operation to cope with this problems, Arid basin district; although at midlatitude, is desert climate because it is far from the ocean and is surrounded by high mountains. Oasis of Hesi Corridor is continuous linearly, but that of arid basin district is sporadic. In $H{\bar{a}}mi$ and $T{\breve{u}}l{\breve{u}}f{\bar{a}}n$(吐魯番) fruit-growing using karez flourishes, And glacier of $Ti{\bar{a}}nshian$(天山) Mts. and $Q{\bar{i}}lian$(祁連) Mts. is very important to arid basin district because of supplying water resource. In the tundra zone surrounding alpine glacier, are distributed widely solifluction lobes and earth hummocks.

• Korean Journal of Soil Science and Fertilizer
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• v.14 no.4
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• pp.195-200
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• 1982

Fused phosphate and slag have used as a sources of phosphate and silicate fertilizers. In order to find out effects of these fertilizers on the growth of young rice plants in nursery, relationships between dry matter production and nutrient uptake at different fertilizer application rates were investigated for two rice varieties, Milyang 23 (a Indica-Japonica hybrid) and Akibare (a Japonica). The results were summarized as followers; 1. The maximum dry matter production was obtained at 75-150 kg/10a of fused phospate and 100-200 kg/10a of slag, respectively, however, a some variations between varieties were recognized. 2. The top/root ratio of varieties around 1.0 was proper for healty see dings and this ratio was reached at application of 75 kg/10a of fused phosphate and 200 kg/10a of slag. 3. The efficiency of applied silicate of rice seedlings was higher in fused phosphate than in slag. 4. The growth of seedling was severely retarded when soil pH was increased above 7 by the application of more than 225 kg/10a of fused phospahte and 400 kg/10a of slag.

• Journal of Photoscience
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• v.12 no.1
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• pp.17-23
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• 2005

Application of a new photocatalyst has been attempted to improve the efficiency and rates of photocatalytic degradation of azo dyes by using a model dye such as Methyl Orange. As a new photocatalyst, $TiO_2$ encapsulated EFAL-removed zeolite Y ($TiO_2$ /EFAL-removed zeolite Y) has been synthesized by ion-exchange in the mixture of EFAL-removed zeolite Y with 0.05 M aqueous [$(NH_4)_2 TiO(C_2O_4)_2.H_2O$] [$TiO(C_2O_4)_2.H_2O$]. This new photocatalyst has been characterized by measuring XRD, IR and reflectance absorption spectra as well as ICP analysis, and it was found that the framework structure of $TiO_2$ /EFAL-removed zeolite Y is not changed by removing the extra-framework aluminum (EFAL) from the normal zeolite Y and the $TiO_2$ inside the photocatalyst exists in the form of $(TiO^{2+})_n$ nanoclusters. Based on the ICP analysis, the Si/Al ratio of the $TiO_2$ /EFAL-removed zeolite Y and the weight of $TiO_2$ were determined to be 23 and 0.061g in 1.0g photocatalyst, respectively. It was also found that adsorption of the azo dye in the $TiO_2$ /EFAL-removed zeolite is very effective (about 80 % of the substrate used). This efficient adsorption contributes to the synergistic photocatalytic activities of the $TiO_2$ /EFAL-removed zeolite by minimizing the required flux diffusion of the substrate. Thus, the photocatalytic reduction of methyl orange (MO) was found to be 8 times more effective in the presence of $TiO_2$ /EFAL-removed zeolite Y than in the presence of $TiO_2$ /normal zeolite Y. Furthermore, the photocatalytic reduction of MO by using 1.0 g of the $TiO_2$ /EFAL-removed zeolite Y containing 0.061g of $TiO_2$ is much faster than that carried out by using 1.0 g of Degussa P-25.

• Economic and Environmental Geology
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• v.28 no.6
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• pp.635-646
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• 1995

Mineralized zone in the Dongyang talc deposits occurs on the lowest dolomite member of the Hyangsanri Dolomite belonging to the Ogcheon Supergroup. Ore bodies are emplaced as pipe-like body along the axis of minor folds plunging $40^{\circ}$ to the west developed in these dolomite layers. Amphibolite and chlorite schist are found along the upper or lower contact of all ore bodies (Kim et al., 1963; Park and Kim, 1966). Following the recrystallization and silicification of dolomite, tremolite and tabular and leafy talc(I) of the earlier stage formed, and microcrystalline talc(II) formed in the later stage. Talc(l) and tremolite formed by the reaction between dolomite and the fluid. Whereas talc (II) formed by the reaction between dolomite and fluid, or by the reaction between early formed tremolite and fluid. During the early stage of mineralization, the fluid was the $H_2O-CO_2$ system dominant in $CO_2$, In the later stage, the composition of the fluid changed to $H_2O-NaCl-CO_2$system, and finally to the $H_2O-NaCl$ system. The pressure and temperature conditions of the formation of tremolite associated with talc(I) were 1,640~2,530 bar, and $440{\sim}480^{\circ}C$, respectively. The pressure and temperature condition of talc(II) ore formation was 1,400~2,200 bar, and $360{\sim}390^{\circ}C$, respectively. These conditions are much lower than the metamorphic pressure and temperature of the rocks from the Munjuri Formation located about 5 km to the noJ:th of Dongyang talc deposit ${\delta}^{13}C$ and ${\delta}^{18}O$ values of dolomite which is the host rock of the talc ore deposit are 2.9~5.7‰ (PDB), and -7.4~l6.8‰ (PDB), respectively. These values are little higher than those from the Cambro-Ordovician limestones of the Taebaeksan region, but belong to the range of the unaltered sedimentary dolomite. ${\delta}^{18}O$and ${\delta}D$ values of the talc from Dongyang deposit are 8.6~15.8‰ (vs SMOW), and -65~-90‰ (vs SMOW), respectively, belonging to the range of magmatic origin. These values are quite different from those measured in the metamorphic rocks of Munjuri and Kyemyungsan Formation. ${\delta}^{34}S$ value of anhydrite is 22.4‰ (CDT), which is much lower than ${\delta}^{34}S$ (30‰ vs COT) of sulfate of early Paleozoic period, and indicates the possibility of the addition of magmatic sulfur to the system. Talc ores show the textures of weak foliation and well developed crenulation cleavages. Talc ore deposit in the area is concluded as hydrothermal replacement deposit formed before the latest phase of the deformations that Ogcheon Belt has undergone.

• Journal of Korean Society of Forest Science
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• v.77 no.3
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• pp.303-314
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• 1988

Tong-ri beach has not enough vegetation to be enjoyed by the sea bathers and to be satisfied with preventing the disaster-damages, but mixed forest near the beach can work its funtions and the old forest of Pirus thunbergii $P_{ARL}$. near the beach do a Little. Therefore it is very urgent to plant more trees near the beach for bathers and disaster-damage prevention. This study was carried out for planning an afforestation, with reporting upon the crown amounts and soil properties of disaster-damage prevention forests of P. thunbergii $P_{ARL}$. planted on the coast sand dunes in 1970 and 1976, and with reporting upon the valuation on soil properties of the lands near the beach in order to set the afforestation site. The results are as follows : 1. In disaster-damage prevention forests, crown surface area and crown volume became increasingly greater in proportion to the height. To D.B.H., crown volume also became increasingly greater in proportion, but crown surface area was directly proportional. 2. In comparison to sail characteristics of sand dune, those of the forests were in large quantity in OM, T-N and avail. $SiO_2$, and almost in the same in avail. $P_2O_5$, but in small quantity in exchangeable canons : K, Ca, Mg and Na. 3. EC, Cl and pH were in small value in the forest soils, but CEC was in large value in those soils. 4. Above facts showed that the forests fulfill their functions for preventing disaster-damages and improve their soil properties. 5. The forests have naturally been thinned up to 34% in 17 years and 39% in 11 years, and one can easily pass through the forest(planted in 1970), because of its sufficient clear-length(2.71m) and its space to pass. 6. A plan for afforestation was oracle nut after judging several sites by the evaluation on the soil properties and considering the best relaxation and the prevention of the various disaster-damages upon which were reported in the last issue. 7. Afforestation should be kept for maintaining its appropriate density for best relaxation and disaster-damage prevention.

• Journal of Fisheries and Marine Sciences Education
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• v.27 no.5
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• pp.1457-1469
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• 2015

This study was undertaken to investigate the quality changes of salted-fermented anchovy meat made by varying the amount of salt during fermentation at $15^{\circ}C$. Anchovy (11.0-14.0 cm of length, 10.7-17.5 g of weight) added with 15-25% of salt was filled in a round form plastic container (i.d. $10.5{\times}11cm$), and then fermented at $15^{\circ}C$ for 110 days. The factors such as proximate composition, pH, color value (L, a, b), TBA value, amino-N content, salinity, hardness value, free amino acid content and sensory evaluation of salted-fermented anchovy meat were measured. Ash content, color value (redness), TBA value, amino-N content. salinity and hardness value of salted-fermented anchovy meat were increased, but color value (lightness), and moisture content were decreased during fermentation at $15^{\circ}C$. A salted-fermented anchovy meat added with 15% of salt was shown higher content of moisture, amino-N content and free amino acid, TBA value than those of 20 or 25% of salt. Ash content, salinity and hardness value were highest in a product added with 25% of salt. From the result of sensory evaluation, Addition amount of 15% salt and fermentation periods of 110 days were determined to be the most desirable palatability of salted-fermented anchovy meat.