• 한국가축번식학회지
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• 제24권1호
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• pp.109-113
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• 2000

단기 고온스트레스가 혈청 cortisol, DHEAS 농도에 미치는 영향을 알아보기 위하여, 단기 고온스트레스 (Short-term TS)를 받은 BALB Ic 생쥐의 혈청 cortisol과 DHEAS 농도를 방사선면역측정 (RIA)을 이용하여 분석하였다. 그 결과 30분 TS를 받은 그룹(T30) 에서 대조군에 비해 cortisol 의 유의적인 증가(P＜0.01)를 보였으나, 120 분 부과 (T120) 시에는 T30 에 비해 유의성 없는 감소를 나타내었다. 이에 반해 DHEAS 의 경우 30분 TS를 받은 그룹 (T30) 과 120 분 TS를 받은 그룹 (T120) 모두에서 대조군에 비해 유의성은 없으나 감소된 경향을 보였다. 특히, DHEAS 의 경우 단기고온 스트레스라는 국한된 스트레스에도 불구하고 지속적인 감소를 나타내었다. 이러한 결과로 보아 단기 고온스트레스가 혈청 cortisol과 DHEAS 농도에 영향을 미치고 있음을 확인할 수 있었다. 또한, 본 연구를 통하여 DHEAS가 스트레스 관련 호르몬임을 확인할 수 있었으며, 스트레스 마커로서 이용될 수 있을 것으로 판단되어진다.

• Asian-Australasian Journal of Animal Sciences
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• 제31권2호
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• pp.263-269
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• 2018

Objective: Heat stress (HS) triggers oxidative stress and respiratory alkalosis in pigs. The objective of this experiment was to study whether a short-term supranutritional amount of dietary vitamin E (VE) can mitigate oxidative stress and respiratory alkalosis in heat-stressed pigs. Methods: A total of 24 pigs were given either a control diet (17 IU/kg VE) or a high VE (200 IU/kg VE; HiVE) diet for 14 d, then exposed to thermoneutral (TN; $20^{\circ}C$, 45% humidity) or HS ($35^{\circ}C$, 35% to 45% humidity, 8 h daily) conditions for 7 d. Respiration rate and rectal temperature were measured three times daily during the thermal exposure. Blood gas variables and oxidative stress markers were studied in blood samples collected on d 7. Results: Although HiVE diet did not affect the elevated rectal temperature or respiration rate observed during HS, it alleviated (all p<0.05 for diet${\times}$temperature) the loss of blood $CO_2$ partial pressure and bicarbonate, as well as the increase in blood pH in the heat-stressed pigs. The HS reduced (p = 0.003) plasma biological antioxidant potential (BAP) and tended to increase (p = 0.067) advanced oxidized protein products (AOPP) in the heat-stressed pigs, suggesting HS triggers oxidative stress. The HiVE diet did not affect plasma BAP or AOPP. Only under TN conditions the HiVE diet reduced the plasma reactive oxygen metabolites (p<0.05 for diet${\times}$temperature). Conclusion: A short-term supplementation with 200 IU/kg VE partially alleviated respiratory alkalosis but did not reduce oxidative stress in heat-stressed pigs.

• Structural Engineering and Mechanics
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• 제47권1호
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• pp.1-25
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• 2013

A combined thermal and mechanical action in roller compacted concrete (RCC) dam analysis is carried out using a three-dimensional finite element method. In this work a numerical procedure for the simulation of construction process and service life of RCC dams is presented. It takes into account the more relevant features of the behavior of concrete such as hydration, ageing and creep. A viscoelastic model, including ageing effects and thermal dependent properties is adopted for the concrete. The different isothermal temperature influence on creep and elastic modulus is taken into account by the maturity concept, and the influence of the change of temperature on creep is considered by introducing a transient thermal creep term. Crack index is used to assess the risk of occurrence of crack either at short or long term. This study demonstrates that, the increase of the elastic modulus has been accelerated due to the high temperature of hydration at the initial stage, and consequently stresses are increased.

• 복식문화연구
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• 제27권1호
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• pp.1-10
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• 2019

Firefighters wear Personal Protective Equipment (PPE) for protection from environmental hazards. However, due to the layers of protective functions, the PPE inevitably adds excessive weight, bulkiness, and thermal stress to firefighters. This study investigated the adverse impact of wearing PPE as an occupational stressor on the firefighter's cognitive functioning. Twenty-three firefighters who had been involved in firefighting at least for 1 year were recruited. The overall changing trend in the firefighter's cognitive functioning (short-term memory, long-term memory, and inductive reasoning) was measured by the scores of three standardized cognitive tests at the baseline and the follow-up, after participating in a moderate-intensity physical activity, wearing a full ensemble of the PPE. The study findings evinced the negative impact of the PPE on the firefighter's cognitive functioning, especially in short-term memory and inductive reasoning. No significant influence was found on the firefighter's long-term memory. The results were consistent when the participant's age and BMI were controlled. The outcomes of the present study will not only fill the gap in the literature, but also provide critical justification to stakeholders, including governments, policymakers, academic communities, and industry, for such efforts to improve human factors of the firefighter's PPE by realizing the negative consequences of the added layers and protective functions on their occupational safety. Study limitations and future directions were also discussed.

• Asian-Australasian Journal of Animal Sciences
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• 제21권7호
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• pp.988-994
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• 2008

The purpose of the investigation was to establish how the pineal-adrenal axis plays an important role in thermoregulation in female goats under short-term heat stress. The study was conducted to observe the influence of glucocorticoids on pineal function in goats and its influence on stress alleviation capability. Melatonin and glucocorticoid secretions and several other endocrine and biochemical blood parameters reflecting the animals well being were determined over a one week period after goats had been exposed to $40^{\circ}C$ and 60% relative humidity for 10 days. Six female goats were used in the study. These animals served as self controls prior to the start of the experiment. The study was conducted for a period of seventeen days in a psychrometric chamber at $40^{\circ}C$ and 60% relative humidity. Chemical pinealectomy was achieved using propranolol followed by exogenous hydrocortisone treatment. Blood samples were drawn twice daily after each treatment to find the effect of hydrocortisone on plasma glucose, total protein, total cholesterol, cortisol, insulin, aldosterone, melatonin and corticosterone. Chemical pinealectomy significantly ($p{\leq}0.05$) affected plasma levels of the parameters studied and these could be significantly ($p{\leq}0.05$) counteracted by administration of hydrocortisone. Chemical pinealectomy aggravated thermal stress, although administration of hydrocortisone could ameliorate the condition. This indicated a role of the pineal in support of thermoregulation. The study establishes the modulating effect of glucocorticoids on pineal activity to relieve thermal stress in goats.

• 한국안전학회지
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• 제9권1호
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• pp.146-154
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• 1994

A series of numerical calculations are performed in order to investigate the dispersion mechanism of toxic gaseous and solid pollutants in extremely short-term and short range. The calculations are carried out in an open space characterized by turbulent boundary layer. The simulation is made by the use of numerical model, in which a control-volume based finite difference method is used together with the SIMPLEC algorithm for the resolution of the pressure-velocity coupling problem. The Reynolds stresses are solved by two-equation, k-$\varepsilon$ model modified for buoyancy. The major parameters consider-ed in this study are temperature, velocity and Injection height of toxic gases, environmental conditions such as temperature and velocity of free stream air, and topographic factor. The results are presented and discussed in detail. The flow field is commonly characterized by the formation of a strong recirculation zone due to the upward motion of the hot toxic gas and ground shear stress. The driving force of the upward motion is explained by the effect of thermal buoyancy of hot gas and the difference of inlet velocity between toxic gas and free stream.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2001년도 하계학술대회 논문집 C
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• pp.1667-1669
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• 2001

The clack of Insulator, which results from internal or external surges such as electrical, mechanical, and thermal stress, might cause ground fault and a power failure without proper repairs. In order to minimize losses caused by a short-term or long-term power failure, it is necessary to detect the deteriorated insulator as early as possible. To do so, we will develop a new device, which can detect and trace an deteriorated insulator by monitoring its physical change the variation of frequency spectrum. This device will do so by finding a Periodic wave sharp (120 Hz), a peculiar wave generated by defused electricity.

• 동력기계공학회지
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• 제16권1호
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• pp.58-64
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• 2012

Power plant boiler is one of the most important utilities providing steam to turbine in thermal power plant. It is composed of thousands of boiler tubes for high efficient heat transfer. Boiler tube material is used in such high temperature and pressure as $540^{\circ}C$, $170kg/mm^2$. The boiler tube material is needed to resist corrosion damage, creep damage and fatigue damage. 2.25%Cr-1Mo steel is used for conventional boiler tubes. In these days steam temperature and pressure of the power plant became higher for high plant efficiency. So, the material property of boiler tube must be upgraded to meet the plant property. Several boiler tube material was developed to meet such condition. X20CrMoV12.1 steel is also developed in early 1980's and used for superheater and reheater tubes in supercritical boilers. The material has martensitic structure, which is difficult to evaluate the material degradation. Boiler tube material at severe condition was tested to evaluate long term and short term degradation and creep. Through long term and high temperature degradation test, lath structure was decreased and recrystallization has been proceeded by sub-crystal. And in this research the effect of temperature and stress on boiler tube characteristic,for example, deformation by creep was changed rapidly at relatively high temperature and stress because creep was affected easily by temperature and stress.

• Biomolecules & Therapeutics
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• 제15권1호
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• pp.58-64
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• 2007

The previous study reported the biological effect of magnetic field exerted by acting on endocrine and anti-oxidant system. The present study aims to study whether ELF-MF (extremely low frequency magnetic field) affects the physiological endocrine systems such as thyroid and whether ELF-MF affects the defense system against oxidative stress when it alters the function of thyroid. Finally, we correlate the effects of MF on oxidative stress, and adrenal and thyroid with an environmental stress factor. We exposed sham or MF to rats for 5 or 25 days. After the exposure, we determined pain sensitivity, level of TSH, $T_3$ and free $T_4$ in plasma. We also assayed in whole brain, lipid peroxidation, the activity of enzymatic anti-oxidant defense including superoxide dismutase(SOD) and glutathione peroxidase (GPx), and non enzymatic defense such as reduced or oxidized glutathione contents. MF induced the hypersensitivity to thermal stimuli with the reduction of latency. $T_3$ and $T_4$ levels were also increased by the exposure of MF. In addition, we observed the rise of MDA level in rat brain by MF although the MF did not change superoxide dismutase and glutathione peroxidase activity. The effect of MF on both reduced and oxidized glutathione results in decrease in reduced or oxidized glutathione in whole brain. In every experiment, there was no significant difference in MF influence between short term (5 days) and long term (25 days) exposure. Taken together, MF exposure affects the thyroid hormonal control in brain. The elevated thyroid hormone acts on brain, leading to hyper-utilization of oxygen. This phenomenon may be correlated with oxidative stress resulting from MF exposure. In conclusion, we suggest that MF exposure may be an environmental stress by exerting oxidative stress.

• Nuclear Engineering and Technology
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• 제55권9호
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• pp.3423-3440
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• 2023

In this work, a multivariate time-series machine learning meta-model is developed to predict the transient response of a typical nuclear power plant (NPP) undergoing a steam generator tube rupture (SGTR). The model employs Recurrent Neural Networks (RNNs), including the Long Short-Term Memory (LSTM), Gated Recurrent Unit (GRU), and a hybrid CNN-LSTM model. To address the uncertainty inherent in such predictions, a Bayesian Neural Network (BNN) was implemented. The models were trained using a database generated by the Best Estimate Plus Uncertainty (BEPU) methodology; coupling the thermal hydraulics code, RELAP5/SCDAP/MOD3.4 to the statistical tool, DAKOTA, to predict the variation in system response under various operational and phenomenological uncertainties. The RNN models successfully captures the underlying characteristics of the data with reasonable accuracy, and the BNN-LSTM approach offers an additional layer of insight into the level of uncertainty associated with the predictions. The results demonstrate that LSTM outperforms GRU, while the hybrid CNN-LSTM model is computationally the most efficient. This study aims to gain a better understanding of the capabilities and limitations of machine learning models in the context of nuclear safety. By expanding the application of ML models to more severe accident scenarios, where operators are under extreme stress and prone to errors, ML models can provide valuable support and act as expert systems to assist in decision-making while minimizing the chances of human error.