• Journal of People, Plants, and Environment
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• v.21 no.6
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• pp.515-521
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• 2018

The purpose of this study was to investigate the effects of horticultural activities with reminiscence materials and singing songs on the ability to recall words and depression in the elderly with mild dementia. A total of 20 sessions of a horticultural therapy program was held once or twice a week from July 14, 2015 to November 3, 2015 for the elderly with mind dementia at the social welfare center in D city. The subjects of this study were 13 women and the mean age was 81.2 years. The ability to recall words significantly improved from $8.6{\pm}1.8$ before the program to $9.4{\pm}0.6$ after the program (p=.012). However, there was no significant difference in the score of depression after the program. Synergistic effects were generated by applying horticultural activities, singing and reminiscence therapy activities simultaneously, and it was effective in recalling memories. As emotional functions were associated with hormones in vivo, there were emotional ups and downs at each session and short-term alternative therapies were not sufficient to completely eliminate neurotoxic substances caused by dementia.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.725-729
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• 2012

Background: The management of hepatolithiasis combined with intrahepatic cholangicarcinoma (IHHCC) remains a challenge due to poor prognosis. The aim of this study was to summarize our diagnosis and cure experience of IHHCC over the recent 10 years. Methods: From January 1996 to January 2006, 66 patients with IHHCC were reviewed retrospectively. Results: Of the 66 patients, 52 underwent surgical resection (radical resection in 38 and palliative in 14) and 8 patients abdominal exploration, while the other 6 cases received endoscopic retrograde biliary internal drainage and stent implantation. In this series, correct diagnosis of advanced stage was made during operation in 8 cases (8/60, 13.3%) and all of them (underwent unnecessary abdominal exploration, among them the positive rate of CA19-9 was 100%, and the positive rate of CEA was 87.6% (7/8), incidence rate of ascites was 100% and short-term significant weight loss was 100%, with median overall survival of only 4 months. Conclusion: Radical resection is mandatory for IHHCC patient to achieve long-term survival, the CT and MR imaging features of IHHCC being concentric enhancement. Patients with IHHCC have significant higher CA199 and significant higher CEA and short-term significant weight loss and ascites should be considered with advanced stage of IHHCC and unnecessary non-therapeutic laparotomies should be avoided.

• Clinical and Experimental Pediatrics
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• v.63 no.8
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• pp.284-290
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• 2020

Korea currently has the world's lowest birth rate but a rapidly inreasing number of preterm infants. The Korean Neonatal Network (KNN), launched by the Korean Society of Neonatology under the support of Korea Centers for Disease Control, has collected population-based data for very low birth weight infants (VLBWIs) born in Korea since 2013. In terms of the short-term outcomes of VLBWIs born from 2013 to 2016 registered in the KNN, the survival rate of all VLBWIs was 86%. Respiratory distress syndrome and bronchopulmonary dysplasia were observed in 78% and 30% of all VLBWIs, respectively. Necrotizing enterocolitis occurred in 7%, while 8% of the VLBWIs needed therapy for retinopathy of prematurity in the neonatal intensive care unit (NICU). Sepsis occurred in 21% during their NICU stay. Intraventricular hemorrhage (grade ≥III) was diagnosed in 10%. In terms of the long-term outcomes for VLBWIs born from 2013 to 2014 registered in the KNN, the post-discharge mortality rate was approximately 1.2%-1.5%, mainly owing to their underlying illness. Nearly half of the VLBWIs were readmitted to the hospital at least once in their first 1-2 years of life, mostly as a result of respiratory diseases. The overall prevalence of cerebral palsy was 6.2%-6.6% in Korea. Bilateral blindness was reported in 0.2%-0.3% of VLBWIs, while bilateral hearing loss was found in 0.8%-1.9%. Since its establishment, the KNN has published annual reports and papers that facilitate the improvement of VLBWI outcome and the formulation of essential healthcare policies in Korea.

• Restorative Dentistry and Endodontics
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• v.39 no.3
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• pp.215-219
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• 2014

Whenever endodontic therapy is performed on mandibular posterior teeth, damage to the inferior alveolar nerve or any of its branches is possible. Acute periapical infection in mandibular posterior teeth may also sometimes disturb the normal functioning of the inferior alveolar nerve. The most common clinical manifestation of these insults is the paresthesia of the inferior alveolar nerve or mental nerve paresthesia. Paresthesia usually manifests as burning, prickling, tingling, numbness, itching or any deviation from normal sensation. Altered sensation and pain in the involved areas may interfere with speaking, eating, drinking, shaving, tooth brushing and other events of social interaction which will have a disturbing impact on the patient. Paresthesia can be short term, long term or even permanent. The duration of the paresthesia depends upon the extent of the nerve damage or persistence of the etiology. Permanent paresthesia is the result of nerve trunk laceration or actual total nerve damage. Paresthesia must be treated as soon as diagnosed to have better treatment outcomes. The present paper describes a case of mental nerve paresthesia arising after the start of the endodontic therapy in left mandibular first molar which was managed successfully by conservative treatment.

• Physical Therapy Korea
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• v.4 no.1
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• pp.48-62
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• 1997

Several studies have evaluated the effects of types of relative frequency and delay interval of knowledge of results(KR) on motor skill learning independently. The purpose of this study was to determine more effective types of KR relative frequency and KR delay interval for motor learning. Forty-six healthy subjects (15 female, 31 male) with no previous experience with this experiment participated. The subjects ranged in age from 20 to 29 years (mean=23.9, SD=0.474). All subjects were assigned to one of four groups: a high-instant group, a high-delay group, a low-instant group, and a low-delay group. During the acquisition phase, subjects practiced movements to a target (400 mm) with either a high (83%) or low (33%) KR relative frequency, and with either an instantaneous or delayed (after 8s) KR. Four groups were evaluated on retention (after 3min and 24hr) and transfer (450 mm) tests. The major findings were as follows: (1) there were no between-group differences in acquisition and short-term retention (p>0.05, (2) a low (33%) KR relative frequency during practice was as effective for learning as measured by both long-tenn retention and transfer tests, compared with high (83%) KR practice conditions (p<0.05), (3) delayed (8s) KR enhanced learning as measured by both long-term retention and transfer tests, compared with instantaneous KR practice conditions (p<0.05), and (4) there were no interactions between KR relative frequency and KR delay interval during acquisition, retention, and transfer phases. The results suggest that relatively less frequent and delayed KR are more effective types for motor learning than more frequent and instantaneous KR.

• PNF and Movement
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• v.12 no.2
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• pp.89-96
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• 2014

Purpose: The purpose of this study was to examine the influence of foot angles on plantar pressure and the center of pressure (COP) trajectory length during level walking. Methods: The study subjects were 30 female university students without orthopedic diseases in the foot. The foot angle was divided into three forms (out-toeing, normal, in-toeing). The subjects practiced each type of gait, and then performed each of level walking, three times, and their averages were calculated. A plantar pressure measurement instrument was used, and the maximum force was obtained by dividing the foot into nine regions covering the anterior medial-lateral, middle medial-lateral, and posterior medial-lateral. The COP trajectory length was statistically processed by obtaining medial-lateral, anterior-posterior, and entire travel distance. Results: During normal walking, the maximum force was significantly higher in the anterior lateral than in the other areas, and the COP trajectory length was significantly shorter in the front-back and entire travel distances (p<0.05). During stair climbing. Conclusion: Walking at abnormal foot angles does not cause appreciable problems in the short term as pressure is concentrated on a specific plantar part. However, it becomes the cause of deformed foot structures and can result in musculoskeletal disabilities in the long term. Therefore, a kinesiatrics-based intervention is required to maintain normal foot angles.

• Biomedical Science Letters
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• v.23 no.2
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• pp.49-56
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• 2017

Fibroblast growth factor (FGF)-2 is one of the most effective growth factors to increase the growth rate of mesenchymal stem cells (MSCs). Previously, we reported that low dose of FGF-2 (1 ng/ml) induced proliferation of bone marrow-derived mesenchymal stem cells (BMSCs) through AKT and ERK activation resulting in reduction of autophagy and senescence, but not at a high dose. In this study, we investigated the effects of high dose FGF-2 (10 ng/ml) on proliferation, autophagy and senescence of BMSCs for long term cultures (i.e., 2 months). FGF-2 increased the growth rate of BMSCs in a dose dependent manner for a short term (3 days), while during long term cultures (2 months), population doubling time was increased and accumulated cell number was lower than control in BMSCs when cultured with 10 ng/ml of FGF-2. 10 ng/ml of FGF-2 induced immediate de-phosphorylation of ERK1/2, expression of LC3-II, and increase of senescence associated ${\beta}$-galactosidase (SA-${\beta}$-Gal, senescence marker) expression. In conclusion, we showed that 10 ng/ml of FGF-2 was inadequate for ex vivo expansion of BMSCs because 10 ng/ml of FGF-2 induced growth retardation via ERK1/2 de-phosphorylation and induction of autophagy and senescence in BMSCs.

• Journal of The Korean Society of Integrative Medicine
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• v.2 no.1
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• pp.1-14
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• 2014

Purpose : The aim of this study was to investigate Activities of Daily Living(ADL) function recovery of repeated measurement of stroke who received ADL training. Method : Twenty stroke patients were treated by ADL program therapy from May to June. All of in twenty stroke patients, 10 stroke patients take part in Occupational Therapy and 10 stroke patients take part in ADL training for 30 min five times a week during four weeks in M- hospital occupational Therapy treatment room, local in Changwon and Geoje. We used two assessment on is Motor Free Visual Perception Test-Third Edition(MVPT-3) for visual perception the other is Modified Barthel Index(MBI) for ADL. Result : First, Visual Short Term Memory(VSTM) score was changed statistical significance OT intervention group than compare with ADL training group(p<.05). Second, Visaul Closure(VC) score was changed statistical significance OT intervention group than compare with ADL training group(p<.05). Third, Spatial Orientation(SO) score was changed statistical significance OT intervention group than compare with ADL training group(p<.05). The fourth Motor Free Visual Perception Test-Third Edition(MVPT-3) score was changed statistical significance OT intervention group than compare with ADL training group(p<.05). The fifth Modified Barthel Index(MBI total) score was changed statistical significance OT intervention group than compare with ADL training group(p<.05). Conclusion : Therefore, ADL training can be on method the visual perception of stroke patients.

• The Journal of Korean Physical Therapy
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• v.34 no.3
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• pp.91-97
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• 2022

Purpose: This study investigated the short-term effectiveness of extracorporeal shock wave therapy (ESWT) on pain, the ankle instability, the ankle function, dorsiflexion range of motion (ROM), and dynamic balance in patients with chronic ankle instability (CAI). Methods: Eighteen participants were divided into an experimental (n=9) and control group (n=9). The ESWT in the experimental group was applied to the lateral collateral ligament in combination with the tibialis anterior whereas the ESWT was applied to the lateral collateral ligament of the ankle alone in the control group. Pain, the ankle instability, the ankle function, dorsiflexion ROM, and dynamic balance were measured using the Visual analog scale, Cumberland ankle instability tool, American Orthopedic Foot and Ankle Society ankle-hindfoot score, weight-bearing lunge, and Y-balance test, before and after ESWT intervention. Results: Significant interactions (group × time) and time effects were observed in the dorsiflexion ROM and dynamic balance. Bonferroni's post-hoc analysis showed that the experimental group revealed a more significant change in dorsiflexion ROM and dynamic balance than the control group. There was a significant time effect in the pain, the ankle instability, and the ankle function, but no significant interaction (group × time) was observed. Conclusion: The ESWT could improve the pain, ankle instability, ankle function, dorsiflexion ROM, and dynamic balance in patients with CAI. Furthermore, the ESWT combined with lateral ankle ligaments and tibialis anterior more improves the dorsiflexion ROM and dynamic balance.

• The Journal of Korean Physical Therapy
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• v.26 no.5
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• pp.308-314
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• 2014

Purpose: The aim of this study was to investigate the effects of gluteal taping on pelvic alignment, trunk stability, and balance during sitting posture in children with unilateral cerebral palsy (CP). Methods: Thirteen children with unilateral cerebral palsy (six females. seven males; mean age 8.5) participated in this study. All participants were evaluated before and after gluteal taping using an Inclinometer for pelvic lateral inclination, trunk impairment scale (TIS) for trunk stability, and modified functional reaching test for balance during sitting. The collected data were analyzed using a paired t-test. Results: The results of this study were as follows: 1) Statistically significant decreases in the angle of pelvic lateral inclination were observed after gluteal taping in children with unilateral CP (p<.05). 2) Statistically significant increases in TIS score were observed after gluteal taping (p<.05). 3) Statistically significant increases in the range of reaching during sitting were observed after gluteal taping (p<.05). Conclusion: : In conclusion, this study showed that gluteal taping improves pelvic alignment, trunk stability, and balance during sitting in children with unilateral cerebral palsy. Further studies will be required to determine the short- and long-term effects of gluteal taping on improving postural symmetry, trunk stability, and balance.