• Childhood Kidney Diseases
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• v.1 no.2
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• pp.161-165
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• 1997

Renal venous thrombosis (RVT) in neonatal period is a rare disease and usually complicated to clinical situations with reduced renal blood flow and hypercoagulability ; like acute blood loss, sepsis, shock, and birth asphyxia. RVT should be suspected in sick babies with hematuria, anemia, thrombocytopenia, enlarged kidney and acute renal failure. And the diagnosis can be confirmed by renal ultrasonography. We report two cases of neonatal renal venous thrombosis with review of literatures. One case, associated with E. coli sepsis, recovered completely, and the other, follwed respiratory distress in the neonate, revealed permanent renal functional impairment.

• Toxicological Research
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• v.32 no.1
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• pp.35-46
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• 2016

No-flow ischemia occurs during cardiac arrest, hemorrhagic shock, liver resection and transplantation. Recovery of blood flow and normal physiological pH, however, irreversibly injures the liver and other tissues. Although the liver has the powerful machinery for mitochondrial quality control, a process called mitophagy, mitochondrial dysfunction and subsequent cell death occur after reperfusion. Growing evidence indicates that reperfusion impairs mitophagy, leading to mitochondrial dysfunction, defective oxidative phosphorylation, accumulation of toxic metabolites, energy loss and ultimately cell death. The importance of acetylation/deacetylation cycle in the mitochondria and mitophagy has recently gained attention. Emerging data suggest that sirtuins, enzymes deacetylating a variety of target proteins in cellular metabolism, survival and longevity, may also act as an autophagy modulator. This review highlights recent advances of our understanding of a mechanistic correlation between sirtuin 1, mitophagy and ischemic liver injury.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.16 no.9
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• pp.783-789
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• 2003

The winding problems of traction motor are the major determinant of motor's life. The root cause of winding failure is gradual deterioration of the insulation due to thermal, electrical, mechanical and environmental stresses. The aging of the insulation reduces the electrical and mechanical strength of the insulation. At same point, a voltage surge or mechanical shock from a traction motor start will fracture or break down the insulation. To achieve the expected life usually requires extensive laboratory evaluation of the insulation systems and the use of accelerated aging tests. There are several nondestructive test available for checking, the condition of motor insulation, the probable extent of aging, and the rate of which aging is taking place. So the insulation characteristics of stator coil were each analyzed by measurement of dielectric loss(tan$\sigma$), capacitance and partial discharge. The method of diagnosis is able to analyze the insulation condition and evaluate the life of the traction motor.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2011.11a
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• pp.182-186
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• 2011

Ejector-diffuser system has long been used in many diverse fields of engineering applications and it has advantages over other fluid machinery, because of no moving parts and structural simplicity. This system makes use of high-pressure primary stream to entrain the low-pressure secondary stream through pure shear actions between two streams. In general, the flow field in the ejector-diffuser system is highly complicated due to turbulent mixing, compressibility effects and sometimes flow unsteadiness. A fatal drawback of the ejector system is in its low efficiency. Many works have been done to improve the performance of the ejector system, but not yet satisfactory, compared with that of other fluid machinery. In the present study, a mixing guide vane was installed at the inlet of the secondary stream for the purpose of the performance improvement of the ejector system. A CFD method has been applied to simulate the supersonic flows inside the ejector-diffuser system. The present results obtained were validated with existing experimental data. The mixing guide vane effects are discussed in terms of the entrainment ratio, total pressure loss as well as pressure recovery.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.5
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• pp.622-637
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• 2017

Fatty acids such as n-3 and n-6 polyunsaturated fatty acids (PUFA) are critical nutrients, used to improve male reproductive performance through modification of fatty acid profile and maintenance of sperm membrane integrity, especially under cold shock or cryopreservation condition. Also, PUFA provide the precursors for prostaglandin synthesis and can modulate the expression patterns of many key enzymes involved in both prostaglandin and steroid metabolism. Many studies carried out on diets supplemented with PUFA have demonstrated their capability to sustain sperm motility, viability and fertility during chilling and freezing as well as improving testis development and spermatogenesis in a variety of livestock species. In addition to the type and quantity of dietary fatty acids, ways of addition of PUFA to diet or semen extender is very crucial as it has different effects on semen quality in male ruminants. Limitation of PUFA added to ruminant ration is due to biohydrogenation by rumen microorganisms, which causes conversion of unsaturated fatty acids to saturated fatty acids, leading to loss of PUFA quantity. Thus, many strategies for protecting PUFA from biohydrogenation in rumen have been developed over the years. This paper reviews four aspects of PUFA in light of previous research including rumen metabolism, biological roles, influence on reproduction, and strategies to use in male ruminants.

• Journal of Chest Surgery
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• v.48 no.3
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• pp.220-224
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• 2015

A patient presented with loss of consciousness and conversion. During an exercise test, catecholaminergic polymorphic ventricular tachycardia (CPVT) resulted in cardiac arrest. He started taking medication (a beta-blocker and flecainide) and an implantable cardioverter defibrillator (ICD) was inserted, but the ventricular tachycardia did not resolve. Left cardiac sympathetic denervation (LCSD) was then performed under general anesthesia, and the patient was discharged on the second postoperative day without complications. One month after the operation, no shock had been administered by the ICD, and an exercise stress test did not induce ventricular tachycardia. Although beta- blockers are the gold standard of therapy in patients with CPVT, thoracoscopic LCSD is safe and can be an effective alternative treatment option for patients with intractable CPVT.

• Korean Journal of Veterinary Research
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• v.44 no.1
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• pp.125-129
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• 2004

A 2-year-old, female, American cocker spaniel dog presented for a 1-year history of severe ascites, exercise intolerance, tachypnea. At that time, she was in an emergency state. First, the dog was stabilized with oxygen therapy. A diagnosis of cardiac problem was made from history, auscultation, radiograph, ECG, and echocardiography. Jugular pulsation was palpated and a harsh, systolic murmur of tricuspid regurgitation was prominent at the right cardiac apex. Tricuspid valve dysplasia (TVD) was confirmed with echocardiography, accompanying enormous myocardial hypertrophy. The clinical signs had been improved for 8 months with careful therapy and periodic abdominocentesis, and ascites was well controlled. The situation, however, became worse quickly in a week because the client did not follow our management schedule. Finally, she died due to dyspnea and shock. After the spontaneous death, necropsy and histopathological examination were performed and when we opened the thorax, a significantly large heart was observed. On histopathological findings, grossly myocardium appeared pale initially, then progressed to yellow and white. Microscopically, there was an extensive hemorrhage along with loss of myocardial striations. Interstitial fibrosis and various degenerative alterations in myocytes were also present.

• Journal of the Korean Society of Costume
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• v.61 no.5
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• pp.34-47
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• 2011

Grotesque make-up causes a visual shock among modern people beyond the standardized beauty definition, attracts their attention, and manifests itself as a phenomenon of "something bizarre, extremely unnatural, ugly, and funny." The purposes of this study were to investigate the characteristics of grotesque in today's make-up as well as its concepts and features and to figure out its aesthetic characteristics based on the results. The research scope was limited to the fashion make-up of the collections from 2005 to 2010 and the advertising make-up during the same period. In the make-up phenomenon examined according to the grotesque characteristics, the pale skin expression, frightened eyes, and emphasis on black induce disgusting fear, sadness, death, sin, fear for life and death, and obsession. As the make-up emphasized only one part by neglecting the original form and exaggerated it to the point of distortion, the exaggerated abnormality led to a sense of social crisis, desperation, and absence of form. As for devilish playfulness, the make-up accompanied by grotesqueness and humor brought the suppressed, closed world in a tight framework out to fluidity and openness, conveying satire, ludicrousness, ridicule, and accusation of the modern society. The heterogeneous disharmony was found in the use of objects in heterogeneous combinations, presenting unreality, fiction, displeasure, ambivalence, and loss of value of human existence.

• Nuclear Engineering and Technology
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• v.41 no.8
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• pp.1045-1052
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• 2009

A calculation model is developed to predict the transient free surface flow on the containment floor following a loss-of-coolant accident (LOCA) of pressurized water reactors (PWR) for the use of debris transport evaluation. The model solves the two-dimensional Shallow Water Equation (SWE) using a finite volume method (FVM) with unstructured triangular meshes. The numerical scheme is based on a fully explicit predictor-corrector method to achieve a fast-running capability and numerical accuracy. The Harten-Lax-van Leer (HLL) scheme is used to reserve a shock-capturing capability in determining the convective flux term at the cell interface where the dry-to-wet changing proceeds. An experiment simulating a sudden break of a water reservoir with L-shape open channel is calculated for validation of the present model. It is shown that the present model agrees well with the experiment data, thus it can be justified for the free surface flow with accuracy. From the calculation of flow field over the simplified containment floor of APR1400, the important phenomena of free surface flow including propagations and interactions of waves generated by local water level distribution and reflection with a solid wall are found and the transient flow rates entering the Holdup Volume Tank (HVT) are obtained within a practical computational resource.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.17 no.5
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• pp.97-102
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• 2018

Combat vehicles require high levels of maneuverability, firepower, armor, and operability. A high-performance power system is required for optimal maneuverability. The fuel pump which supplies fuel stably is very important to achieve this. The fuel pump consists of a pump part, a motor part, and a control part. It is equipped with a BLDC motor. Numerous failures of the fuel pump occurred during vehicle operation when exposed to vibration, shock, and high temperature. The cause of failure was confirmed to be stator slip of the BLDC motor. Stator slip is a consequence of the interference loss between the stator and the housing of the motor part in an high temperature environment. The failure of the fuel pump was solved through size control of the motor housing and the stator. We performed vibration testing at high temperature for verification. This study contributes to improving the reliability of combat vehicles.