• Proceedings of the Korean Reliability Society Conference
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• 2004.07a
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• pp.147-151
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• 2004

In this study, an optical fiber assembly directly coupled with a laser diode or a photo diode is designed to confirm high reliable optical coupling efficiency of optical transmitter(Tx) and receiver(Rx). The optical fiber assembly is fabricated by soldering an optical fiber and a Kovar ferrule using a glass solder after inserting an optical fiber through a Kovar ferrule. The Kovar which has good welding characteristics is applied to introduce laser welding technique. The glass solder has excellent thermal characteristics such as thermal shift delamination compared with PbSn, AuSn solder previously used usually. Furthermore, the glass solder doesn't need fiber metalization and this enables low cost fabrication. However, the glass soldering is high temperature process over 35$0^{\circ}C$ and the convex shape after solidification due to surface tension causes the stress concentration on optical fiber. The stress concentration on the optical fiber increases the optical insertion loss and possibility of crack formation. The shape of glass solder was designed referring to 2-D Axi-symmetric FEM simulation. To test the mechanical reliability, mechanical vibration test and shock test were done according to Telcorida GR-468-Core protocol. After each test, the optical loss of the stress distributed fiber assembly didn't exceed 0.5 dB, which passes the test.

• Radiation Oncology Journal
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• v.24 no.4
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• pp.317-321
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• 2006

A case is reported of a man with malignant fibrous histiocytoma (MFH) in right thigh who developed streptococcal toxic shock syndrome (STSS) during postoperative radiotherapy. Before radiotherapy, a patient complained wax and wane lymphedema following wide excision of tumor mass which was confirmed as MFH. He took some nonsteroidal antiinflammatory drug (NSAID) for about one month. He suffered preexisting hepatitis C virus (HCV) infection, diabetes and well-controlled hypertension. The patient received conventional radiotherapy to right thigh with a total dose of 32.4 Gy at 1.8 Gy per day. At last radiotherapy fraction, cutaneous erythematous inflammation was suddenly developed at his affected thigh. At that time, he also complained of oliguria, fever and chills. The patient was consulted to internal medicine for adequate evaluation and management. The patient was diagnosed as suggested septic shock and admitted without delay. At admission, he showed hypotension, oliguria, constipation, abnormal renal and liver function. As a result of blood culture, Streptococcus pyogenes was detected. The patient was diagnosed to STSS. He was treated with adequate intravenous antibiotics and fluid support. STSS is one of oncologic emergencies and requires immediate medical intervention to prevent loss of life. In this patient, underlying HCV infection, postoperative lymphedema, prolonged NSAID medication, and radiotherapy may have been multiple precipitating factors of STSS.

• Structural Engineering and Mechanics
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• v.32 no.2
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• pp.193-212
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• 2009

The resilience of a city confronted with a terrorist bomb attack is the background of the paper. The resilience strongly depends on vital infrastructure and the physical protection of people. The protection buildings provide in case of an external explosion is one of the important elements in safety assessment. Besides the aspect of protection, buildings facilitate and enable many functions, e.g., offices, data storage, -handling and -transfer, energy supply, banks, shopping malls etc. When a building is damaged, the loss of functions is directly related to the location, amount of damage and the damage level. At TNO Defence, Security and Safety methods are developed to quantify the resilience of city infrastructure systems (Weerheijm et al. 2007b). In this framework, the dynamic response, damage levels and residual bearing capacity of multi-storey RC buildings is studied. The current paper addresses the aspects of dynamic response and progressive collapse, as well as the proposed method to relate the structural damage to a volume-damage parameter, which can be linked to the loss of functionality. After a general introduction to the research programme and progressive collapse, the study of the dynamic response and damage due to blast loading for a single RC element is described. Shock tube experiments on plates are used as a reference to study the possibilities of engineering methods and an explicit finite element code to quantify the response and residual bearing capacity. Next the dynamic response and progressive collapse of a multi storey RC building is studied numerically, using a number of models. Conclusions are drawn on the ability to predict initial blast damage and progressive collapse. Finally the link between the structural damage of a building and its loss of functionality is described, which is essential input for the envisaged method to quantify the resilience of city infrastructure.

• Journal of Yeungnam Medical Science
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• v.34 no.2
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• pp.174-181
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• 2017

Ferroptosis is a newly recognized type of cell death that results from iron-dependent lipid peroxidation and is different from other types of cell death, such as apoptosis, necrosis, and autophagic cell death. This type of cell death is characterized by mitochondrial shrinkage with an increased mitochondrial membrane density and outer mitochondrial membrane rupture. Ferroptosis can be induced by a loss of activity of system $X_c{^-}$ and the inhibition of glutathione peroxidase 4, followed by the accumulation of lipid reactive oxygen species (ROS). In addition, inactivation of the mevalonate and transsulfuration pathways is involved in the induction of ferroptosis. Moreover, nicotinamide adenine dinucleotide phosphate oxidase and p53 promote ferroptosis by increasing ROS production, while heat shock protein beta-1 and nuclear factor erythroid 2-related factor 2 inhibit ferroptosis by reducing iron uptake. This article outlines the molecular mechanisms and signaling pathways of ferroptosis regulation, and explains the roles of ferroptosis in human disease.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2007.11a
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• pp.327-331
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• 2007

Inundation of substation and underground power equipment(pad-mounted transformers & switches) breaks out every summer season in low-lying downtown and low-lying shore by localized heavy rain, typhoon and tidal wave. In case inundation of substation and underground power equipment, it occurs a great economic loss owing to recovery time and events of electric shock occur by inundation electrical facility. So we search the damage situation and installation situations. Therefore we propose the necessity of protection of flood at low-lying downtown and low-tying shore. This paper will be used to present a reform proposal of electrical related law about flood protection of existing power equipment.

• Proceedings of the KIEE Conference
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• 2003.07b
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• pp.1285-1287
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• 2003

The aging of the insulation reduces the electrical and mechanical strength of the insulation. At same point, a voltage surge or mechanical shock from a traction motor start will fracture or break down the insulation. To achieve the expected life usually requires extensive laboratory evaluation of the insulation systems and the use of accelerated aging tests. There are several nondestructive test available for checking. the condition of motor insulation, the probable extent of aging, and the rate of which aging is taking place. So the insulation characteristics of stator coil were each analyzed by measurement of dielectric loss($tan{\delta}$), capacitance and partial discharge. The method of diagnosis is able to analyze the aging condition and predict the life of the traction motor.

• Journal of The Korean Astronomical Society
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• v.26 no.1
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• pp.1-12
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• 1993

In order to explore the time dependence of the closure parameters of the two-fluid calculations for supernova remnants and the terminal shocks of stellar winds, we have considered a simple model in which the time evolution of the cosmic-ray distribution function was followed in the test-particle limit using the Bohm diffusion model. The particles are mostly accelerated to relativistic energy either in the free expansion phase of the SNRs or in the early phase of the stellar winds, so the evolution of the closure parameters during these early stages is substantial and should be followed correctly. We have also calculated the maximum momentum which is limited by either the age or the curvature of these spherical shocks. We found that SNRs expanding into the medium where the gas density decreases with the distance from the explosion center might be necessary to explain the observed power-law distribution of the galactic cosmic rays. The energy loss due to the escaping energetic particles has been estimated for the terminal shocks of the stellar winds.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.40 no.8
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• pp.519-525
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• 2016

In a pump, from the performance point of view, it is very important to minimize the shock loss at the inlet of the rotor blades. In this study, the effects of shape and install angle of the inlet guide on the performance of an axial-flow pump are numerically simulated using commercial CFD code, Ansys CFX. Finally, to obtain the optimized shape of the vanes and the install angle of the vanes in the inlet guide under given operating conditions, optimization analysis is conducted using Analysis design exploration based on response surface optimization.

• Proceedings of the KSME Conference
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• 2008.11a
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• pp.1022-1027
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• 2008

This paper represents a study on the conceptual design of new automatic bicycle transmission. The gear change in a commercial bicycle is carried out by moving the chain between sprockets. By the use of a multiple sprocket for speed change the power loss and transmission shock may occur. To solve the problem of bicycle transmission, the improved solution was derived by the technical contradiction matrix of TRIZ. The conceptual solution is one sprocket which replaces the function of multiple sprockets and adapts actively to the pitch of chain. And it was confirmed to be an adequate design through the Independence Axiom of design axiom.

• The Bulletin of The Korean Astronomical Society
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• v.45 no.1
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• pp.55.1-55.1
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• 2020

In an attempt to investigate the nonlinear dynamics such as shock, shear, and turbulence associated with ultra-relativistic jets, we develop a new relativistic hydrodynamics (RHD) code based on the weighted essentially non-oscillatory (WENO) scheme. It is a 5th-order accurate, finite-difference scheme, which has been widely used for solving hyperbolic systems of conservation equations. The code is parallelized with MPI and OpenMP. Through an extensive set of tests, the accuracy and efficiency of different WENO reconstructions, and different time discretizations are assessed. Different implementations of the equation of state (EOS) for relativistic fluid are incorporated, As the fiducial setup for simulations of ultra-relativistic jets, we adopt the EOS in Ryu et al. (2006) to treat arbitrary adiabatic index of relativistic fluid, the WENO-Z reconstructions to minimize numerical dissipation without loss of stability, and the strong stability preserving Runge-Kutta (SSPRK) method to achieve stable time stepping with large CFL numbers. In addition, the code includes a high-order flux averaging along the transverse directions for multi-dimensional problems, and the modified eigenvalues for the acoustic modes to effectively control the carbuncle instability. We find that the new code performs satisfactorily simulations of ultra-relativistic jets.