• Journal of Veterinary Clinics
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• v.33 no.1
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• pp.65-69
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• 2016

A 10-year-9-month-old spayed female Shih Tzu was presented with ocular discharge and corneal opacity to Veterinary Medical Teaching Hospital of Seoul National University. Complete ophthalmic examination revealed bilateral keratoconjunctivitis sicca accompanied by the severe corneal neovascularization and edema in the right eye (OD). Ultrasound biomicroscopy incidentally showed an iridociliary mass located at 6~7 o'clock in the OD. No evidence of metastasis was observed on thoracic and abdominal radiography. Enucleation was selected and performed on the OD, considering the risk of metastasis or recurrence. Non-invasive and pigmented iridociliary adenoma was confirmed on histopathological evaluation.

• Journal of Veterinary Clinics
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• v.34 no.3
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• pp.185-188
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• 2017

This study assessed the seroprevalence of Babesia gibsoni in companion dogs in Korea by enzyme linked immunosorbent assay using recombinant BgTRAP antigen. Dogs were randomly selected from those admitted for various reasons to local private veterinary hospitals and the Animal Medical Center of Chonbuk National University. With the owners' permission, extra blood was drawn from each dog for serological assays. Of the 188 selected dogs, seven (3.72%) were positive for B. gibsoni, including six of 167 (3.59%) indoor and one of 12 (8.33%) outdoor dogs. Of the seven dogs positive for B. gibsoni, four were aged > 10 years, two were < 1 year, and one was between 1 and 10 years; and two were Yorkshires and one each was Shih-tzu, Maltese, Pekinese, beagle and mixed. Concurrent diseases or chief complaints were anemia in two dogs, both of which had a history of confirmed babesiosis by polymerase chain reaction, and non-anemic diseases in five. Geographically, four dogs were from Jeonbuk/Jeonju, and one each from Seoul, Gyounggi-do, and Jeonnam/Gwangju. To our knowledge, this is the first report of companion dogs in Korea being seropositive for B. gibsoni. Serologic screening of subclinical or carrier dogs can detect this potentially dangerous disease and assess its epidemiology.

• Journal of Veterinary Clinics
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• v.34 no.3
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• pp.197-199
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• 2017

A 14-year-old castrated male ShihTzu diagnosed with chronic kidney disease (CKD) 6 months prior was referred to our clinic. The patient had been experiencing symptoms such as vomiting, poor appetite and hind limbs weakness. Hematology tests showed that he had a non-regenerative anemia. With aggressive treatment, the patient's state had gotten worse. He showed ragged breath, vomiting blood and loss of consciousness temporarily. Hematocrit maintained low level. Gastric hemorrhage was strongly suspected by hematemesis. Whole blood transfusion was performed and heparin was used as an anticoagulant. Prior to transfusion, the blood cross matching between donor and patient was performed and the result was compatible. After the transfusion was stabilized, 1 mg of protamine sulfate for each 100 units of heparin was prepared and given intravenously over 3 minutes to reverse the effects of heparin. Immediately after protamine injection, the patient conducted severe anaphylactic shock. Protamine sulfate is used to reverse the anticoagulant action of heparin in dogs and humans. The adverse reaction of protamine sulfate range from mild reaction to fetal cardiac arrest. When using protamine sulfate as heparin neutralization, it can lead to the death of a patient cause of anaphylactic shock. For this reason, the protamine sulfate should be injected slowly with antihistamine and the clinician should carefully monitor patients.

• Journal of Veterinary Clinics
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• v.25 no.1
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• pp.40-43
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• 2008

A 5-year-old male Shih-Tzu dog was referred with the primary complaint of scrotal swelling after surgery of urethrotomy 1 week ago. A diagnosis of the patient was made based on history taking, physical examination, laboratory examination, radiography, and ultrasonography. In the blood analysis, increase of leukocyte was seen. And there were enlarged and heterogeneous parenchyma of right testis in ultrasonic evaluation. The case was diagnosed as periorchiepididymitis and followed by treatment with bilateral orchiectomy and postoperative antibacterial agents. And conditions of patient were good.

• Journal of Veterinary Clinics
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• v.24 no.2
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• pp.229-232
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• 2007

A 7-year-old Shih Tzu cross dog was presented for severe abdominal pain, persistent vomiting and anorexia. Laboratory tests revealed mild anemia and hypoproteinemia. Abdominal survey radiography revealed marked gastric distension and large circular foreign body in the gastric pylorus. The foreign body was removed using a videoendoscope, fishing line and retrieval forceps. The dog's clinical signs resolved following foreign body removal.

• Journal of Veterinary Clinics
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• v.24 no.3
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• pp.449-452
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• 2007

A 2 year-old intact male Shih-tzu dog was presented with a history of snakebite on the left upper lip. He was depressed and had swelling, erythema and pain around the left muzzle. Both mandibular lymph nodes were swollen. Fang marks were not clear, but there were scratch wounds and prolonged bleeding. Hemogram revealed neither thrombocytopenia nor echinocytosis. Increased CK value in serum chemistry and myoglobinuria in urine analysis meant muscle injury. With careful monitoring, fluid, corticosteroid, antihistamine and antibiotics were administered. After the application of ice pack and suction, local symptoms changed for the worse. However, any other systemic disorders were not identified. After 5 days, the facial swelling had resolved completely.

• Journal of Veterinary Clinics
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• v.34 no.2
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• pp.103-107
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• 2017

A 7-year-old spayed female Shih-tzu dog with 4-month history of anorexia and weight loss was diagnosed with splenic hemangiosarcoma. One week after splenectomy, the dog developed severe, multifocal, coalescing erosive and ulcerative dermatosis with epidermal collarettes and crusts on the dorsal trunk. The dog was prescribed systemic antibiotics comprising cephradine and enrofloxacin postoperatively. Histopathological examination of skin biopsies from haired skin lesions revealed changes consistent with pemphigus foliaceus (PF). Tentative diagnosis for this patient was pemphigus-like drug reaction resulting from cephradine treatment. However, given the dog's history of hemangiosarcoma, paraneoplastic pemphigus (PNP), a rarely reported cancer-related pemphigus in dogs, was also considered for tentative diagnosis. Significant clinical remission of dermal lesions was achieved with four weeks of prednisolone and mycophenolate mofetil (MMF) treatment. Drugs were gradually tapered and eventually discontinued with concurrent reduction of dermal lesions, and no further recurrence was noted.

• Journal of Veterinary Clinics
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• v.37 no.1
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• pp.34-37
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• 2020

A 1-year-old castrated male Shih-Tzu dog presented with severe orbital swelling involving the right eye. Physical examination identified a painless swelling of the right periocular tissues and protrusion of the third eyelid. Radiographic examination revealed a well-delineated, spherical (3 × 3 cm) soft tissue mass. Ultrasonography confirmed a hypoechoic, multilobular, tubular cystic structure with hyperechoic foci. Fine needle aspiration was conducted and the cytologic impression revealed copious mucus, increased neutrophilic leucocytes, and foamy macrophages. Th tentative diagnosis was zygomatic sialocele, and the lesion was resected through lateral orbitotomy. Surgical exploration identified a multilobular mass adhering to the zygomatic glands. Both the zygomatic gland and the mass were removed. Histological findings were consistent with those of an inflamed myxoma. No postoperative recurrence occurred within 1 year.

• Journal of Veterinary Clinics
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• v.35 no.6
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• pp.302-307
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• 2018

This report describes the unusual ultrasonography features of chronic hypertrophic pyloric gastropathy in two dogs - a 12-year-old neutered male Pekingese (case 1) and an 11-year-old spayed female Shih Tzu (case 2) - with chronic vomiting and weight loss. Chronic hypertrophic pyloric gastropathy can be observed as the focal thickening of the pyloric wall with normal layers on ultrasonography images. However, in case 1, gastric neoplasia could not be ruled out because of the presence of regional lymph node enlargement; in case 2, an intussusception was tentatively diagnosed because of a mass within the pylorus, which appeared to be connected to the descending duodenum on the longitudinal image. In both cases, focally thickened pyloric walls were demonstrated through exploratory laparotomy, and the histopathological diagnosis of chronic hypertrophic pyloric gastropathy was made. Ultrasonography is useful for imaging the gastrointestinal tract, and the typical ultrasonographic features of chronic hypertrophic pyloric gastropathy have been reported. However, the possibility, that chronic hypertrophic pyloric gastropathy can present unusual ultrasonographic findings similar to those of tumors or intussusception, should also be considered.

• Journal of Veterinary Clinics
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• v.38 no.6
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• pp.310-314
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• 2021

Compared to the other chemodectoma, aortic body tumors, the carotid body tumor is rarer and more often malignant. In the present case, a 12-year-old, intact female Shih-tzu dog presented to the hospital with a right ventral cervical mass. The mass was diagnosed by immunohistochemical staining with chromogranin A (CgA) as a carotid body tumor. The cervical mass and metastasized lymph node were removed by surgical resection. Because the dog had valvular heart disease, chemotherapy with carboplatin was initiated over 6 months to prevent metastasis and recurrence as an adjunctive treatment. After over two years of management, tumor metastasis and recurrence were not observed until recently. This report shows that proper management and chemotherapy as an adjunctive therapy can treat carotid body tumors in elderly dogs with concurrent heart disease.