• Bulletin of the Korean Chemical Society
• /
• v.22 no.5
• /
• pp.467-475
• /
• 2001

A triblock copolymer based on $poly(\varepsilon-caprolactone)$ (PCL) as the hydrophobic part and poly(ethylene glycol) (PEG) as the hydrophilic portion was synthesized by a ring-opening mechanism of ${\varepsilon}-caprolactone$ with PEG containing a hydroxyl group at bot h ends as an initiator. The synthesized block copolymers of PCL/PEG/PCL (CEC) were confirmed and characterized using various analysis equipment such as 1H NMR, DSC, FT-IR, and WAXD. Core-shell type nanoparticles of CEC triblock copolymers were prepared using a dialysis technique to estimate their potential as a colloidal drug carrier using a hydrophobic drug. From the results of particle size analysis and transmission electron microscopy, the particle size of CEC core-shell type nanoparticles was determined to be about 20-60 nm with a spherical shape. Since CEC block copolymer nanoparticles have a core-shell type micellar structure and small particle size similar to polymeric micelles, CEC block copolymer can self-associate at certain concentrations and the critical association concentration (CAC) was able to be determined by fluorescence probe techniques. The CAC values of the CEC block copolymers were dependent on the PCL block length. In addition, drug loading contents were dependent on the PCL block length: the larger the PCL block length, the higher the drug loading content. Drug release from CEC core-shell type nanoparticles showed an initial burst release for the first 12 hrs followed by pseudo-zero order release kinetics for 2 or 3 days. CEC-2 block copolymer core-shell type nanoparticles were degraded very slowly, suggesting that the drug release kinetics were governed by a diffusion mechanism rather than a degradation mechanism irrelevant to the CEC block copolymer composition.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2020.11a
• /
• pp.25-26
• /
• 2020

During the molding process of the existing interlocking block, the pigment is firstly laid, and cement is poured on the pigment secondly to give vibration. Interlocking blocks made of conventional cement are entirely dark where the pigment area is removed. On the other hand, when looking at the mortar with oyster shells added, the color is closer to that of the existing cement mortar. Therefore, if an interlocking block is produced by adding a pigment to a mortar with an oyster shell added, it is considered that the amount of pigment is less than that of the existing interlocking block. This study is a basic study of interlocking blocks. To investigate the strength characteristics of mortar using oyster shell powder as aggregate, W/C is 25%, 50%, oyster shell replacement rate is 0%, 25%, 50%, 75%, 100% was substituted to make a mortar and its strength change was studied.

• Journal of Welding and Joining
• /
• v.34 no.2
• /
• pp.11-15
• /
• 2016

FE analyses for weldment of ship structure are required for various reasons such as stress concentration for bead tow, residual stress and distortion after welding, and hydrogen diffusion for prediction of low temperature crack. These analyses should be done by solid element modeling, but most of ship structures are modeled by shell element. If we are able to make solid element in the shell element FE modeling it is easily to solve the requirement for solid elements in weld analysis of large ship structures. As the nodes of solid element cannot take moments from nodes of shell element, these two kinds of element cannot be used in one model by conventional modeling. The PSCM (Perpendicular shell coupling method) can connect shell to solid. This method uses dummy perpendicular shell element for transferring moment from shell to solid. The target of this study is to develop a FE pre-processing system applicable at welding at ship structure by using PSCM. We also suggested glue-contact technique for controlling element numbers and element qualities and applied it between PSCM and solid element in automatic pre-processing system. The FE weldment modeling through developed pre-processing system will have rational stiffness of adjacent regions. Then FE results can be more reliable when turn-over of ship-block with semi-welded state or ECA (Engineering critical assessment) of weldment in a ship-block are analyzed.

• Bulletin of the Korean Chemical Society
• /
• v.23 no.6
• /
• pp.872-879
• /
• 2002

One of the improtant characteristics of core-shell type nanoparticles is the long-term storage and reuse as an aqueous injection solution when required. For this reason, reconstruction of lyophilized core-shell type nanoparticles is considered to be essential . BAB type triblock copolymers differ from AB type diblock copolymers, which contain the A block as a hydrophilic part and the B block as a hydrophobic part. by not being easily redistributed into phosphate-buffered saline (PBS, pH 7.4, 0.1 M). Therefore, lyophilized core-shell type nanoparticles of CEC triblock copolymer were reconstituted using a somication process with a bar-type sonicator in combination with a freezing-thawing process. Soncation for 30s only resuspended CEC nanoparticles in PBS; their particle size distribution showed a monomodal pattern with narrow size distribution. The bimodal size distribution pattern and the aggregates were reduced by further sonication for 120 s but these nanoparticles showed a wide size distribution. The initial burst of drug release was increased by reconstitution process. The reconstitution of CEC core-shell type nanoparticles by freezing-thawing resulted in trimodal distribution pattern and formed aggregates, although freezing-thawing process was easier than sonication . Drug release form CEC nanoparticles prepared by freezing-thawing was slower than from the original dialysis solution. Although core-shell typenanoparticles of CEC triblock copolymers were not easily performed. Cytotoxicity testing of core-shell type nanoparticles of CEC-2 triblock copolymers containing clonazepam (CNZ) was performed using L929 cells. Cytotoxicity of CNZ was decreased by incorporation into nanoparticles.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.14 no.6
• /
• pp.2554-2575
• /
• 2020

Data hiding technology hides secret information into the carrier, so that when the carrier is transmitted over network, it will not attract any malicious attention. Using data compression, it is possible to reduce the data size into a small compressed code, which can effectively reduce the time when transmitting compressed code on the network. In this paper, the main objective is to effectively combine these two technologies. We designed a data hiding scheme based on two techniques which are turtle-shell information hiding scheme and absolute moment block truncation coding. The experimental results showed that the proposed scheme provided higher embedding capacity and better image quality than other hiding schemes which were based on absolute moment block truncation coding.

• Journal of Welding and Joining
• /
• v.28 no.1
• /
• pp.54-59
• /
• 2010

Ship Blocks are assembled by welding, and among them, welding between large blocks (Pre-erection stage) is used as feature of butt. In this process, local material has a experience of thermal cycle and become finally shrunk. As for inconsistency of shrunk weldments and adjacent regions, ship structure would be deformed locally and globally. Thermal distortion analyses are done for control of these processes, and methodologies capable of ship block size among them are using 2-D shell element in FEM. A shell element takes charge of plate, so it has its thickness which is important for angular distortion by welding. By the way, a butt-welding consists normally of several passes, and weldment thickness are different at each pass. If a calculated final one-time welding shrinkage is acting on the shell element whose thickness is same as it of plate, then deformation value must be underestimated. This research developed a methodology that total deformation after multi-pass welding can be analyzed by one time at shell element having original thickness of its plate. We use the SDB thermal distortion analysis method and verified by several experiment. The both experimental and analysis results showed good agreements.

• Bulletin of the Korean Chemical Society
• /
• v.25 no.7
• /
• pp.1025-1030
• /
• 2004

A hybrid linear polymer-dendrimer block copolymer, poly(ethylene glycol)-block-poly(L-lysine) dendrimer, was synthesized and introduced to form polyionic complexes with DNA. The copolymer formed core-shell type nanoparticles with plasmid DNA. From dynamic light scattering experiments, the mean diameter of the polyplexes was observed to be 154.4 nm. The complex showed much increased water solubility compared to poly(L-lysine). The plasmid DNA in polyplexes was efficiently protected from the enzymatic digestion of DNase I. The cytotoxicity and transfection efficiency for 293 cells was measured in comparison with poly(Llysine).

• Geotechnical Engineering
• /
• v.14 no.3
• /
• pp.109-122
• /
• 1998

In the design and construction of Keystone block reinforced wall with geogrid, previous on the behaviour of wall in curved area is required. This study is to investigate the structural stability of wall and problems during construction in curved area. Previous analyzing methods, usually used for straight area of wall, have been reviewed to find any problems in applying to stability analysis of curved area. Thus, the purpose of this study is to show how to analyse the straight area of Keystone block wall first, and then turn this to use for analyzing various significance, concerning the design or construction of curved high keystone block wall. and the stress behavior on retaining wall between straight and curved conditions by F.E.M, using the shell analysis theory.

• Bulletin of the Korean Chemical Society
• /
• v.22 no.3
• /
• pp.261-262
• /
• 2001

• Special Issue of the Society of Naval Architects of Korea
• /
• 2011.09a
• /
• pp.90-94
• /
• 2011

Longitudinal shell member that arranged block unit on 3D-curved surface is performed manual working by designer considering spacing of division characteristic, location and twisting at geometrical 3-dimensional form. Shell expansion drawing that drawn by initial design and shell landing work performed by hull production design have overlap of design work in terms of arrangement of shell longitudinal member. In this study, eliminate design overlap on shell member arrangement that is one of ship longitudinal member. Develop shell member optimization and auto arrangement system.