• Title/Summary/Keyword: Severe tests

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Experimental studies into a new type of hybrid outrigger system with metal dampers

  • Wang, A.J.
    • Structural Engineering and Mechanics
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    • v.64 no.2
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    • pp.183-194
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    • 2017
  • This paper presents the experimental investigation into a new type of steel-concrete hybrid outrigger system developed for the high-rise building structure. The steel truss is embedded into the reinforced concrete outrigger wall, and both the steel truss and concrete outrigger wall work compositely to enhance the overall structural performance of the tower structures under extreme loads. Meanwhile, metal dampers of low-yield steel material were also adopted as a 'fuse' device between the hybrid outrigger and the column. The damper is engineered to be 'scarified' and yielded first under moderate to severe earthquakes in order to protect the structural integrity of important structural components of the hybrid outrigger system. As such, not brittle failure is likely to happen due to the severe cracking in the concrete outrigger wall. A comprehensive experimental research program was conducted into the structural performance of this new type of hybrid outrigger system. Studies on both the key component and overall system tests were conducted, which reveal the detailed structural response under various levels of applied static and cyclic loads. It was demonstrated that both the steel bracing and concrete outrigger wall are able to work compositely with the low-yield steel damper and exhibits both good load carrying capacities and energy dispersing performance through the test program. It has the potential to be applied and enhance the overall structural performance of the high-rise structures over 300 m under extreme levels of loads.

Clinical Study on Safety and Efficacy of JiSaiXin (Recombinant Human Granulocyte Colony Stimulating Factor Injection Manufactured in China) for Chinese Undergoing Chemotherapy

  • Wang, Lin;Huang, Xin-En
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.299-301
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    • 2015
  • Objectives: To assess safety and efficacy of JiSaiXin (Recombinant Human Granulocyte Colony Stimulating Factor Injection manufactured in China, G-CSF) 150ug per day for three days and whether this regimen could reduce the incidence of febrile neutropenia caused by chemotherapy. Method: From July 2014 to December 2014 patients treated by chemotherapy in our hospital were randomly divided into two groups: Group A with prophylactic use of G-CSF (JiSaiXin) 24 hours after chemotherapy for consecutive 3 days; and Group B with G-CSF (JiSaiXin) after neutropenia. Routine blood tests were performed 7 days and 14 days after chemotherapy. Results: A total of 100 patients fulfilled study criteria, and the incidence of severe neutropenia (grade III/IV) and the incidence of febrile neutropenia in Group A were lower than those in Group B. Nine patients were found severe neutropenia (grade III/IV) in Group B, but one in Group A, three febrile neutropenia in Group B, but 0 in Group A. Conclusions: This study suggested that prophylactic use of G-CSF (JiSaiXin) 150ug per day 24 hours after chemotherapy for consecutive 3 days is safe and could be effective for preventing febrile neutropenia in patients with chemotherapy.

Analysis of Transient Maneuvers for Objectifying Evaluation of Vehicle Stability (차량 안정성 평가의 객관화를 위한 과도 운동 분석)

  • Kim, Jung-Sik;Kim, Young-Tae;Yoon, Yong-San
    • Transactions of the Korean Society of Automotive Engineers
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    • v.14 no.1
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    • pp.167-175
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    • 2006
  • Directional stability is important performance in vehicle and tire design. The current methods to analyze this is generally based on linear concept. Using the existing concept, it cannot realistically explain the subjective assessment at all because it is hard to practically represent the nonlinear behaviour of a complex vehicle system in reality. In this paper, new method to analyze directional stability is introduced. At first, directional stability of vehicle is categorized into yaw, rear axle, and roll stability. In order to objectify these items, driver perceptual parameters based on subjective assessment are used. Using the perceptual parameters, it can successfully explain the transient maneuver of vehicle and extract objective parameters for directional stability. Finally, these objective parameters are successfully validated through two handling tests, lane change and severe lane change. The correlation results show that there exists a good correlation between subjective assessment and the proposed objective parameters.

A Pediatric Case of Long-term Untreated Distal Renal Tubular Acidosis

  • Kedsatha, Philavanh;Shin, Hee Young;Choi, Yong;Cheong, Hae Il;Cho, Tae-Joon;Yi, Eunsang;Maisai, Mayfong
    • Childhood Kidney Diseases
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    • v.24 no.2
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    • pp.115-119
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    • 2020
  • Distal renal tubular acidosis (dRTA) is a rare renal tubular disorder characterized by normal anion gap metabolic acidosis, hypokalemia, and high urine pH. It can be inherited or acquired. In untreated pediatric patients with dRTA, rickets and growth retardation are common. We report the case of a 12-year-old Lao girl who presented with typical clinical features of dRTA with severe bone deformities that developed after a bed-ridden state due to a bicycle accident at the age of 8 years. Initial laboratory tests revealed metabolic acidosis with a normal anion gap, hypokalemia, and alkali urine. Renal ultrasonography revealed bilateral medullary nephrocalcinosis. Whole exome sequencing revealed no pathogenic mutations. After treatment with oral alkali, potassium, and vitamin D, she could walk and run. Later, she underwent corrective orthopedic surgeries for bony deformities. Thus, in pediatric dRTA patients, despite severe symptoms remaining untreated, accurate diagnosis and proper management can improve quality of life.

RAIM - A MODEL FOR IODINE BEHAVIOR IN CONTAINMENT UNDER SEVERE ACCIDENT CONDITION

  • KIM, HAN-CHUL;CHO, YEONG-HUN
    • Nuclear Engineering and Technology
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    • v.47 no.7
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    • pp.827-837
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    • 2015
  • Following a severe accident in a nuclear power plant, iodine is a major contributor to the potential health risks for the public. Because the amount of iodine released largely depends on its volatility, iodine's behavior in containment has been extensively studied in international programs such as International Source Term Programme-Experimental Program on Iodine Chemistry under Radiation (EPICUR), Organization for Economic Co-operation and Development (OECD)-Behaviour of Iodine Project, and OECD-Source Term Evaluation and Mitigation. Korea Institute of Nuclear Safety (KINS) has joined these programs and is developing a simplified, stand-alone iodine chemistry model, RAIM (Radio-Active Iodine chemistry Model), based on the IMOD methodology and other previous studies. This model deals with chemical reactions associated with the formation and destruction of iodine species and surface reactions in the containment atmosphere and the sump in a simple manner. RAIM was applied to a simulation of four EPICUR tests and one Radioiodine Test Facility test, which were carried out in aqueous or gaseous phases. After analysis, the results show a trend of underestimation of organic and molecular iodine for the gas-phase experiments, the opposite of that for the aqueous-phase ones, whereas the total amount of volatile iodine species agrees well between the experiment and the analysis result.

Long-limb Roux-en-Y Reconstruction after Subtotal Gastrectomy to Treat Severe Diabetic Gastroparesis

  • Park, Joong-Min;Kim, Jong Won;Chi, Kyong-Choun
    • Journal of Gastric Cancer
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    • v.19 no.3
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    • pp.365-371
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    • 2019
  • The role of surgical intervention in patients with diabetic gastroparesis is unclear. We report a case of a 37-year-old man with a history of recurrent episodes of vomiting and long-standing type 2 diabetes mellitus. Esophagogastroduodenoscopy did not reveal any findings of reflux esophagitis or obstructive lesions. A gastric emptying time scan showed prolonged gastric emptying half-time (344 minutes) indicating delayed gastric emptying. Laboratory tests revealed elevated fasting serum glucose and glycosylated hemoglobin (HbA1c, 12.9%) and normal fasting C-peptide and insulin levels. We performed Roux-en-Y reconstruction after subtotal gastrectomy to treat gastroparesis and improve glycemic control, and the patient showed complete resolution of gastrointestinal symptoms postoperatively. Barium swallow test and gastric emptying time scan performed at follow-up revealed regular progression of barium and normal gastric emptying. Three months postoperatively, his fasting serum glucose level was within normal limits without the administration of insulin or oral antidiabetic drugs with a reduced HbA1c level (6.9%). Long-limb Roux-en-Y reconstruction after subtotal gastrectomy may be useful to treat severe diabetic gastroparesis by improving gastric emptying and glycemic control.

Severe Paraspinal Muscle Atrophy with Fatty Degeneration in a Young Adult: A Case Report (젊은 성인의 척추주위근에 발생한 지방 변성을 동반한 심한 근위축: 증례보고)

  • Huh, Jae-Won;Yang, Won-Jong;Park, Eunhee;Lee, Jae Eun;Kim, Chul-Hyun
    • Journal of Electrodiagnosis and Neuromuscular Diseases
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    • v.20 no.2
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    • pp.130-134
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    • 2018
  • A 36-year-old male patient developed diffuse low back pain. His past medical history was unremarkable and had no family history of neuromuscular disease. He had no bladder and bowel problems. Creatine kinase was 172 U/L (normal < 170). Other fluid and blood chemistry tests were normal. Manual muscle test grades of extremities and sensory examination were normal. Muscle stretch reflexes were normal. Fasciculations and myotonia were not detected. Straight leg raising test was negative. There was no spinal root compression, spinal stenosis, or signal intensity change of spinal cord on magnetic resonance imaging (MRI). Fatty change and atrophy of the cervical, thoracic and lumbar paraspinal muscles were noted on MRI. Nerve conduction studies were normal. Electromyography showed 1+ positive sharp waves in the lumbar paraspinal muscles. Electromyography of upper and lower extremity muscles revealed no abnormal spontaneous activity. We report a rare case of severe paraspinal muscle atrophy with fatty degeneration in a Young Adult.

Critical heat flux in a CANDU end shield - Influence of shielding ball diameter

  • Spencer, Justin
    • Nuclear Engineering and Technology
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    • v.54 no.4
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    • pp.1343-1354
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    • 2022
  • Experiments were performed to measure the critical heat flux (CHF) on a vertical surface abutting a coarse packed bed of spherical particles. This geometry is representative of a CANDU reactor calandria tubesheet facing the end shield cavity during the in-vessel retention (IVR) phase of a severe accident. Deionized light water was used as the working fluid. Low carbon steel shielding balls with diameters ranging from 6.4 to 12.7 mm were used, allowing for the development of an empirical correlation of CHF as a function of shielding ball diameter. Previously published data is used to develop a more comprehensive empirical correlation accounting for the impacts of both shielding ball diameter and heating surface height. Tests using borosilicate shielding balls demonstrated that the dependence of CHF on shielding ball thermal conductivity is insignificant. The deposition of iron oxide particles transported from shielding balls to the heating surface is verified to increase CHF non-trivially. The results presented in this paper improve the state of the knowledge base permitting quantitative prediction of CHF in the CANDU end shield, refining our ability to assess the feasibility of IVR. The findings clarify the mechanisms governing CHF in this scenario, permitting identification of potential future research directions.

Characterization of Product Surface according to Tool Surface Conditions when Forming TRIP1180 Steel Sheets with PVD CrN-coated Tools (PVD CrN 코팅 금형의 TRIP1180 판재 성형 시 금형의 표면상태에 따른 제품 표면특성 평가)

  • J. H. Bang;G. H. Bae;M. Kim;M. G. Lee;H. G. Kim;J. H. Song
    • Transactions of Materials Processing
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    • v.32 no.5
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    • pp.247-254
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    • 2023
  • This study conducted the wear tests on bending punches coated with PVD CrN and examined the surface quality of the product formed by each punch in the forming of uncoated TRIP1180 sheets. The study quantitatively estimated the surface quality of the product by measuring the roughness and imaging the product surface. The correlation between the punch wear depth and the product surface roughness was quantitatively analyzed. The results showed that before failure occurs, the product roughness was comparable with that of the as-received, and the product surface was smooth without scratches and defects. However, after failure, the punch wear is caused by fretting wear mechanism, and a punch whose coating is not completely peeled plows the product surface, resulting in severe scratches with grooves and ridges on the product surface. Severe wear on the punch surface caused by fretting wear can rapidly degrade the product surface quality as it is directly affected by the punch surface condition, and the product surface quality accurately reflects the punch wear condition.

Epidemiological Characteristics of COVID-19 in Chungju City from 2021 July to 2021 December (2021년 7월 - 2021년 12월 충주시 COVID-19의 역학적 특성)

  • Cheon-Hoo Jeon;Jungtae Leem
    • The Journal of Korean Medicine
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    • v.44 no.3
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    • pp.47-58
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    • 2023
  • Objectives: This study aimed to investigate the epidemiological characteristics of COVID-19 in Chungju City from July to December 2021. Methods: The authors processed and analyzed the epidemiological analysis report written by researcher. The estimated reproduction rate was analyzed using web-based software that calculates time-varying reproduction numbers. The results were analyzed through univariate multiple regression analysis, with a maximum significance level set at 0.05. Results: During the study period, a total of 1,188 patients were identified, with 7.9% of them progressing to a severe status. The maximum reproduction rate recorded was 3.48. Factors associated with the transition to a severe status included the presence of symptoms at the time of diagnosis, lack of vaccination, and belonging to the age group over 40. Conclusion: Based on the findings of this study, it can be strongly supported that the measures implemented in Chungju City, such as social distancing, vaccination, and preemptive diagnostic tests, were appropriate. Furthermore, it demonstrates that Chungju City effectively managed the impact of COVID-19. Korean Medicine Doctors made significant contributions to the epidemiological investigations of COVID-19. To comprehensively manage infectious diseases, it is crucial to provide administrative and legal support and encourage active research to expand the role of Korean Medicine Doctors in this area.