• Title/Summary/Keyword: Set Association

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Gene Set Analyses of Genome-Wide Association Studies on 49 Quantitative Traits Measured in a Single Genetic Epidemiology Dataset

  • Kim, Jihye;Kwon, Ji-Sun;Kim, Sangsoo
    • Genomics & Informatics
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    • v.11 no.3
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    • pp.135-141
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    • 2013
  • Gene set analysis is a powerful tool for interpreting a genome-wide association study result and is gaining popularity these days. Comparison of the gene sets obtained for a variety of traits measured from a single genetic epidemiology dataset may give insights into the biological mechanisms underlying these traits. Based on the previously published single nucleotide polymorphism (SNP) genotype data on 8,842 individuals enrolled in the Korea Association Resource project, we performed a series of systematic genome-wide association analyses for 49 quantitative traits of basic epidemiological, anthropometric, or blood chemistry parameters. Each analysis result was subjected to subsequent gene set analyses based on Gene Ontology (GO) terms using gene set analysis software, GSA-SNP, identifying a set of GO terms significantly associated to each trait ($p_{corr}$ < 0.05). Pairwise comparison of the traits in terms of the semantic similarity in their GO sets revealed surprising cases where phenotypically uncorrelated traits showed high similarity in terms of biological pathways. For example, the pH level was related to 7 other traits that showed low phenotypic correlations with it. A literature survey implies that these traits may be regulated partly by common pathways that involve neuronal or nerve systems.

Set Menu Preferences of Middle and High School Students in School Foodservice (남녀 중,고등학생의 학교급식 세트메뉴에 대한 선호도)

  • Lee, Na-Yeong;Gwak, Dong-Gyeong;Lee, Gyeong-Eun
    • Journal of the Korean Dietetic Association
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    • v.13 no.1
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    • pp.1-14
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    • 2007
  • The purpose of this study was to assess students’ preference on set menus served in school foodservice. Questionnaires were distributed to 4,050 students enrolled in 34 middle and high schools located in Seoul, Gyeonggi, and Gyeongnam provinces. The students were asked to assess their preferences on 78 set menus using a 5-point Likert-type scale(1 : very dislike - 5 : very like). Excluding responses with significant missing data, usable responses were 3,433. Data were analyzed with descriptive analysis, t-test, and one-way analysis of variance. There was no difference between middle and high school students in terms of set menu preferences. On the other hand, there was significant difference between boys' and girls' set menu preferences. Among the seven given set menu groups(rice and soup with side dishes, tangs, rice with toppings, fried rice, western foods, noodles.ddeokguk.dumpling soups, and bibimbaps), boys had higher preference scores for the rice and soup with side dishes, tangs, rice with toppings, and fried rice than that of girls. Fried rice set menus were chosen to be boys’ favorite menus while western food set menus were most preferred by the girls. Rice and soup with side dishes set menus were least preferred by both boys and girls.

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A Review of Minimum Data Sets and Standardized Nursing Classifications (보건의료정보 자료 세트의 비교 및 간호정보 표준화에 대한 고찰)

  • Yom Young-Hee;Lee Ji-Soon;Kim Hee-Kyung;Chang Hae-Kyung;Oh Won-Ok;Choi Bo-Kyung;Park Chang-Sung;Chun Sook-Hee;Lee Jung-Ae
    • The Journal of Korean Academic Society of Nursing Education
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    • v.5 no.1
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    • pp.72-85
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    • 1999
  • The paper presents a review of three data sets(Uniform Hospital Discharge Data Set, Nursing Minimum Data Set, and Nursing Management Minimum Data Set) and six major nursing classifications(the North American Nursing Diagnoses Association Taxonomy I, Omaha System, Nursing Interventions Classification, Nursing Intervention Lexicon and Taxonomy, Nursing Outcome Classification, Nursing Outcomes Classification, and Classification of Patient Outcome). The reviewed data sets and nursing classifications were different from each other in the purpose, structure, and user. Nursing Interventions Classification and Nursing Outcomes Classification were linked to North American Nursing Diagnosis Association, but others not. The data set and nursing classifications need to be linked to other data sets and classifications.

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Efficient Part-of-Speech Set for Knowledge-based Word Sense Disambiguation of Korean Nouns (한국어 명사의 지식기반 의미중의성 해소를 위한 효과적인 품사집합)

  • Kwak, Chul-Heon;Seo, Young-Hoon;Lee, Chung-Hee
    • The Journal of the Korea Contents Association
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    • v.16 no.4
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    • pp.418-425
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    • 2016
  • This paper presents the part-of-speech set which is highly efficient at knowledge-based word sense disambiguation for Korean nouns. 174,000 sentences extracted for test set from Sejong semantic tagged corpus whose sense is based on Standard korean dictionary. We disambiguate selected nouns in test set using glosses and examples in Standard Korean dictionary. 15 part-of-speeches which give the best performance for all test set and 17 part-of-speeches which give the best performance for accuracy average of selected nouns are selected. We obtain 12% more performance by those part-of-speech sets than by full 45 part-of-speech set.

Assessment Using the ICF-core set for Children and Youth with Cerebral Palsy: A Single Case Study

  • Yun, YuNa;Choi, GoEun;Lim, Hyoung won
    • The Journal of Korean Physical Therapy
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    • v.31 no.2
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    • pp.103-110
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    • 2019
  • Purpose: This study evaluated the usefulness of International Classification of Functioning, disability and health core set for children and youths with cerebral palsy (ICF-core set for CP) by comparing the Gross Motor Function Measure-88 (GMFM-88), which is the most widely used outcome measure in children with cerebral palsy (ICF-core set for CP). Method: One subject (Female, 14) was evaluated by GMFM-88 and ICF-core set for CP. In addition, the concept of GMFM-88 was compared with the concept of the ICF-core set for CP in compliance with ICF linking rules. The numerical values both of the GMFM-88 categories and the ICF-core set for CP's items were compared. Results: The ICF b760 was linked to the GMFM-88 59~61. d415 was linked to 57~58 of GMFM-88. d450 was linked to GMFM-88's 65~72. d455 was linked to GMFM-88 at 77and 80~83. Conclusion: The association of the ICF-core set for CP and GMFM-88 was confirmed. In addition, the number of categories of ICF-core set for CP was smaller than the number of items of GMFM-88. In conclusion, the ICF-core set for CP is an evaluation tool that can identify the various features of children. In addition, GMFM-88 was linked to the ICF core set for CP according to the ICF linking rules.

A Preliminary Study to the Validity of 'Attachment Q-set' as a Measuring Tool for 5 Years' Attachment (만 5세 애착측정도구로서의 '애착 Q-set' 예비 타당도 연구)

  • Seo, Seon Ok;Shim, Mi Kyung
    • Korean Journal of Child Studies
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    • v.36 no.3
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    • pp.175-194
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    • 2015
  • The purpose of this preliminary study was to investigate the validity of the 'Attachment Q-set' as a measuring tool for 5 years attachment stability. The subjects comprised 18 boys and 15 girls aged 5 in a daycare center in G city, in Kyongnam. The instruments used in this study were 'Attachment Q-set', ASCT, and IPPA-R. Based on experts' rating, the Q-set was modified, reducing it from 90 to 75 items, and used a Likert 5-points scale. ASCT scores as well as types were compared with the scores of the Q-set and IPPA-R. The attachment type was classified into either secure or insecure. The IPPA-R score of the secure infants was significantly higher than the insecure, and correlated with the ASCT score. However, there was no significant correlation between the Q-set score with the attachment types or the ASCT scores. The Q-set scores were partially correlated with the IPPA-R. This results were discussed in terms of the Q-set's invalidity for rating attachment levels of 5 years as well as the limitations imposed by the subjects' restrictive numbers.

A Longitudinal Study on Students' Misconception patterns of Electric Current (전류에 관한 학생들의 오인 유형변화의 종단적 연구)

  • Moon, Choong-Sik;Kwon, Jae-Sool
    • Journal of The Korean Association For Science Education
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    • v.11 no.1
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    • pp.1-14
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    • 1991
  • The objectives of the study is to examine students concepts changes using a longitudinal study. The study compared two data sets collected in 1989 and in 1990 using the same instrument and subjects. The first data set was collected by Ahn(Ahn, 1989). In the study, students' patterns of misconceptions were examined in the following aspects : 1) Comparison of the students' misconception before observation of actual phenomenon in the first data between the two data sets. 2) The analysis of the patterns of students misconceptions of the second data set In terms of students' patterns of conceptual change before and after observation in the first data set. In the study, overall patterns of students' misconceptions appeared in the second data set were similar to those of the first data set ; however, about 40% of individual student's patterns of misconceptions were changed. Even the students who changed their opinion from misconception to scientific by observing the give phenomenon in the previous study(the first data set) returned to their original misconception after one year. The researcher interpreted this phenomenon in terms of the characteristics of the three kinds of cognitive conflict suggested by Kwon(Kwon, 1989).

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A Study on the Development of Criterion Scores for the Maternal Behavior Q-set in Korea (모성행동 Q-set의 국내 준거 개발 연구)

  • 구미향
    • Journal of the Korean Home Economics Association
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    • v.36 no.11
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    • pp.129-139
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    • 1998
  • The purpose of this study was to develop criterion scores for the Korean version of the Maternal Behavior Q-set. The Maternal Behavior Q-set was developed as a means of describing maternal behavior at home. This Q-set consists of 90 items which are sorted to reflect the degree of similarity with mother's observed behavior. A mother's sensitives score is the correlation between this description of her behavior with the criterion scores of Maternal sensitivity. The criterion scores of Maternal sensitivity were developed by 10 judges who are cognizant in attachmet theory and maternal behavior in natural contexts. The correlation among each of the 10 judge's maternal sensitivity scores was grater than .72. The maternal sensitivity criterion scores developed for Korean mothers correlated highly with the criterion scores for North American mothers. And the interobservers' correlation of the sensitivity scores ranged between. .47∼.93. According to the items in the Maternal Behavior Q-set judged to be most like and most unlike the prototypically sensitive mothers, "When baby is distressed, mother is able to quickly and accurately identify the source" proved to be the most sensitive maternal behavior item. "Mother seldom speaks to the baby directly" was the least sensitive maternal behavior item.

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Pan evaporation modeling using deep learning theory (Deep learning 이론을 이용한 증발접시 증발량 모형화)

  • Seo, Youngmin;Kim, Sungwon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2017.05a
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    • pp.392-395
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    • 2017
  • 본 연구에서는 일 증발접시 증발량 산정을 위한 딥러닝 (deep learning) 모형의 적용성을 평가하였다. 본 연구에서 적용된 딥러닝 모형은 deep belief network (DBN) 기반 deep neural network (DNN) (DBN-DNN) 모형이다. 모형 적용성 평가를 위하여 부산 관측소에서 측정된 기상자료를 활용하였으며, 증발량과의 상관성이 높은 기상변수들 (일사량, 일조시간, 평균지상온도, 최대기온)의 조합을 고려하여 입력변수집합 (Set 1, Set 2, Set 3)별 모형을 구축하였다. DBN-DNN 모형의 성능은 통계학적 모형성능 평가지표 (coefficient of efficiency, CE; coefficient of determination, $r^2$; root mean square error, RMSE; mean absolute error, MAE)를 이용하여 평가되었으며, 기존의 두가지 형태의 ANN (artificial neural network), 즉 모형학습 시 SGD (stochastic gradient descent) 및 GD (gradient descent)를 각각 적용한 ANN-SGD 및 ANN-GD 모형과 비교하였다. 효과적인 모형학습을 위하여 각 모형의 초매개변수들은 GA (genetic algorithm)를 이용하여 최적화하였다. 그 결과, Set 1에 대하여 ANN-GD1 모형, Set 2에 대하여 DBN-DNN2 모형, Set 3에 대하여 DBN-DNN3 모형이 가장 우수한 모형 성능을 나타내는 것으로 분석되었다. 비록 비교 모형들 사이의 모형성능이 큰 차이를 보이지는 않았으나, 모든 입력집합에 대하여 DBN-DNN3, DBN-DNN2, ANN-SGD3 순으로 모형 효율성이 우수한 것으로 나타났다.

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Care Labeling Compliance (의류제품에 부착된 Care Label 에 관한 연구)

  • 박광희
    • Journal of the Korean Home Economics Association
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    • v.33 no.2
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    • pp.159-166
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    • 1995
  • The purpose of the present study is to investigate how closely care labels comply with the 1984 version of the Care Labeling Rule, as well as the change in degree of compliance prior to and after the 1988 IFI care label campaign. Label information was analyzed on the basis of country of origin. The information was also divided into two sets. The basis for dividing the data into two sets was the beginning of the IFI care label campaign in 1988 The data were obtained from 1147 checklists. The information for 1147 samples in six clothing categories were collected from department, specialty, and discount stores. Chi-square analyses were conducted to test hypotheses. While there was no significant difference in the number of incorrect labels on domestically produced garments compared to imported garments in set 1, there was a significant difference in set 2. Also, there was a significnat differnece in the number of incorrect labels between in set 1 and in set 2.

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