• Korean Journal of Schizophrenia Research
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• v.22 no.2
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• pp.21-33
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• 2019

Objectives: The current study covers a secondary revision of the guidelines for the pharmacotherapy of schizophrenia issued by the Korean Medication Algorithm for Schizophrenia (KMAP-SCZ) 2001, specifically for co-existing symptoms and antipsychotics-related side-effects in schizophrenia patients. Methods: An expert consensus regarding the strategies of pharmacotherapy for positive symptoms of schizophrenia, co-existing symptoms of schizophrenia, and side-effect of antipsychotics in patients with schizophrenia was retrieved by responses obtained using a 30-item questionnaire. Results: For the co-existing symptoms, agitation could be treated with oral or intramuscular injection of benzodiazepine or antipsychotics; depressive symptoms with atypical antipsychotics and adjunctive use of antidepressant; obsessive-compulsive symptoms with selective serotonin reuptake inhibitors and antipsychotics other than clozapine and olanzapine; negative symptoms with atypical antipsychotics or antidepressants; higher risk of suicide with clozapine; comorbid substance abuse with use of naltrexone or bupropion/varenicline, respectively. For the antipsychotics-related side effects, anticholinergics (extrapyramidal symptom), propranolol and benzodiazepine (akathisia), topiramate or metformin (weight gain), change of antipsychotics to aripiprazole (hyperprolactinemia and prolonged QTc) or clozapine (tardive dyskinesia) could be used. Conclusion: Updated pharmacotherapy strategies for co-existing symptoms and antipsychotics-related side effects in schizophrenia patients as presented in KMAP-SCZ 2019 could help effective clinical decision making of psychiatrists as a preferable option.

• Journal of agriculture & life science
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• v.50 no.1
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• pp.33-43
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• 2016

Drought tolerant species from 26 Korean native plants were selected using different physiological indicators. Arundinella hirta, Solanum carolinense and Carpesium divaricatum were withered after 8days of the stopping of irrigation. Plants except Kummerowia striata, Lespedeza cuneata and Ulmus parvifolia were withered in over 80% at 9-10days of the irrigation stopping. K. striata was withered after 10days, and L. cuneata and U. parvifolia were withered in over 90% after 11days of the stopping of irrigation. As stopping experiment of irrigation, A. hirta, S. carolinense, C. divaricatum, K. striata, L. cuneata and U. parvifolia were proved to be drought tolerant species. Among those plant species, transpiration rate of Cassia mimosoides var. nomame Makino was high as 0.042ml/㎠·4hr. However, unit transpiration rate of U. parvifolia and L. cuneata were 0.005 and 0.010ml/㎠·4hr, respectively. In testing of physiological indicators, leaf area and transpiration rate were different among plant species. Unit transpiration rate of U. parvifolia was lower compared with other plant species. L. cuneata, U. parvifolia, Kummerowia striata, Arundinella hirta and C. divaricatum were high in relative water content and low in relative water loss. As this results, L. cuneata and U. parvifolia. were identified as drought tolerant species.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.7 no.3
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• pp.383-391
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• 2017

In image processing, image segmentation has been studied by various methods in a long time. Image segmentation is the process of partitioning a digital image into multiple objects and face detection is a typical image segmentation field being used in a variety of applications that identifies human faces in digital images. In this paper, we propose a method for extracting the contours of faces included in images. Using the Viola-Jones algorithm, to do this, we detect the approximate locations of faces from images. But, the Viola-Jones algorithm could detected the approximate location of face not the correct position. In order to extract a more accurate face region from image, we use skin color in this paper. In details, face region would be extracted using the analysis of horizontal and vertical histograms on the skin area. Finally, the face contour is extracted using snake algorithm for the extracted face area. In this paperr, a modified snake energy function is proposed for face contour extraction based snake algorithm proposed by Williams et al.[7]

• Journal of Industrial Convergence
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• v.21 no.7
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• pp.93-104
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• 2023

This study was designed to evaluate effects of Patients Empowerment Program for Schizophrenia (PEPS) on Empowerment, Internalized Stigma, Self-esteem, and Quality of Life, in people with chronic schizophrenia living in a rural community. A non-equivalent control group repeated measures design was used. Participants were 22 persons with chronic schizophrenia enrolled from O Province Mental Health Welfare Center, South Korea. (experimental group= 10, control group = 12). The PEPS was administered to the experimental group, consisting of 16 sessions delivered twice a week for 8 weeks. SPSS/WIN 26.0 was used to analyze the collected data using χ²-test, independent t-test, Fisher's exact test, and repeated measures ANOVA. Upon completion of PEPS, the experimental group showed a significantly increased in Self-esteem (F=6.09, p=.005) and Quality of Life (F=3.37, p=.044) as compared to the control group. However, there was no significant difference between the two groups between Empowerment and Internalized Stigma. The results suggest that the PEPS may be an effective intervention for improving Self-esteem and Quality of Life.

• The Journal of Bigdata
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• v.7 no.2
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• pp.153-172
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• 2022

Online shopping has transformed and rapidly grown the entire market at the forefront of wholesale and retail services as an effective solution to issues such as digital transformation and social distancing policy (COVID-19 pandemic). Small business owners, who form the majority at the center of the online shopping industry, are constantly collecting policy changes and market trend information to overcome these problems and use them for marketing and other sales activities in order to overcome these problems and continue to grow. Objective and refined information that is more closely related to the business is also needed. Therefore, in this paper, through the collection and analysis of big data information, which is the core technology of digital transformation, key variables are set in product classification, sales trends, consumer preferences, and review information of online shopping malls, and a method of using them for competitor comparison analysis and business sustainability evaluation has been prepared and we would like to propose it as a service. If small and medium-sized businesses can benchmark competitors or excellent businesses based on big data and identify market trends and consumer tendencies, they will clearly recognize their level and position in business and voluntarily strive to secure higher competitiveness. In addition, if the sustainable growth of the online shopping mall operator can be confirmed as an indicator, more efficient policy establishment and risk management can be expected because it has an improved measurement method.

• Nutrition Research and Practice
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• v.17 no.4
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• pp.682-697
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• 2023

BACKGROUND/OBJECTIVES: Tibetan tea is a kind of dark tea, due to the inherent complexity of natural products, the chemical composition and beneficial effects of Tibetan tea are not fully understood. The objective of this study was to unravel the composition of Tibetan tea using knowledge-guided multilayer network (KGMN) techniques and explore its potential antioxidant and hypolipidemic mechanisms in mice. MATERIALS/METHODS: The C57BL/6J mice were continuously gavaged with Tibetan tea extract (T group), green tea extract (G group) and ddH2O (H group) for 15 days. The activity of total antioxidant capacity (T-AOC) and superoxide dismutase (SOD) in mice was detected. Transcriptome sequencing technology was used to investigate the molecular mechanisms underlying the antioxidant and lipid-lowering effects of Tibetan tea in mice. Furthermore, the expression levels of liver antioxidant and lipid metabolism related genes in various groups were detected by the real-time quantitative polymerase chain reaction (qPCR) method. RESULTS: The results showed that a total of 42 flavonoids are provisionally annotated in Tibetan tea using KGMN strategies. Tibetan tea significantly reduced body weight gain and increased T-AOC and SOD activities in mice compared with the H group. Based on the results of transcriptome and qPCR, it was confirmed that Tibetan tea could play a key role in antioxidant and lipid lowering by regulating oxidative stress and lipid metabolism related pathways such as insulin resistance, P53 signaling pathway, insulin signaling pathway, fatty acid elongation and fatty acid metabolism. CONCLUSIONS: This study was the first to use computational tools to deeply explore the composition of Tibetan tea and revealed its potential antioxidant and hypolipidemic mechanisms, and it provides new insights into the composition and bioactivity of Tibetan tea.

• Therapeutic Science for Rehabilitation
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• v.11 no.1
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• pp.35-47
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• 2022

Objective : In this study, we conducted a questionnaire survey of occupational therapists to examine their perceptions on and willingness to provide telerehabilitation dementia prevention education. Methods : From March 13 to 19, 2021, a questionnaire survey targeting occupational therapists in Busan, Ulsan, and Gyeongnam was conducted. 100 questionnaires were distributed but only 70 were collected. The collected data were subjected to frequency analysis and descriptive statistics using the statistical program SPSS version 23.0. Results : The average scores by region were as follows. The average compatibility score was highest at 3.92 score, intention to providing education, doctors 3.89 score, community-centric rehabilitation awareness 3.81 score, cost saving 3.78 score, perceiver usefulness 3.75 score, accessibility 3.62 score, the quality of telerehabilitation service was in order of 3.49 score. Conclusion : All items asking whether occupational therapists participate in community-centered rehabilitation and non-face-to-face dementia prevention education programs showed high scores, indicating the willingness to participate actively. In the future, in addition to follow-up research on the implementation of telerehabilitation dementia prevention education, measures for improving accessibility within the local and national government should be discussed.

• 한국노년학
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• v.29 no.1
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• pp.37-50
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• 2009

The purpose of the present study was to develop a community-based intensive health care program for the community dwelling elderly to strength their functional status and to verify the effect on their geriatric syndrome. A one-group pretest-posttest design was used for the study. A total of 69 frail elderly, who lived in the area within 20 minutes by car, were committed themselves to the day care center(Sangikjae), and had the ability of verbal communication were selected from G city in Kyunggi province. The participants completed a set of questionnaires to measure the sub-score of frailty, fall, urinary incontinence, malnutrition, and mild cognitive disorder domain, using the Otasha-Kensin through the physical examinations and interviews. After 4 weeks of intervention, the outcome was measured to evaluate the effects of the program, and the data obtained were analyzed using descriptive statistics, paired t-test and McNemar test. The results showed that the sub-score of frailty, fall, urinary incontinence, and malnutrition domain were statistically significantly decreased after intervention except those of urinary incontinence and mild cognitive disorder domain, implying that the risk of frailty, fall, and malnutrition was decreased. These findings indicated that community-based the intensive health care program is effective for relieving geriatric syndrome of the community dwelling elderly.

• 한국노년학
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• v.31 no.4
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• pp.999-1014
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• 2011

The purpose of this study is to examine the effects of long-term care insurance(macro-system) on family relationship(micro-system)s' change based on ecosystems theory. Data come from the second(2007) and the fourth(2009) Korean Welfare Panel Study(KWPS). Experimental group is the beneficiary using long-term care insurance and the member of household in their households, and control group is the non-beneficiary not using long-term care insurance and the member of household in their households. The main findings of difference-in-difference model analysis are as follows. First, the ecosystems theory is a theory examining the correlation between long-term care insurance and family relationship. Second, the effects of long-term care insurance is not income effect but independent effect. This result shows that the meaning of family has faded away and family relationship has been weaken and that long-term care insurance has not complete characteristics as a social insurance. Thus, system reforms of long-term care insurance is highly needed for system comprehensiveness, coverage, adequacy, and service accessibility and is changed into family-friendly social policy.

• 한국노년학
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• v.31 no.2
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• pp.371-380
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• 2011

This study was to address changes on hospital-based home care utilization after long-term care insurance(LTCI) was launched. National electronic data information(EDI) on hospital-based home care from Health Insurance Review Agency in 2007.7~2008.6(prior to LTCI) and in 2009(posterior to LTCI) was analyzed. After the launch of long-term care insurance, 40 hospital-based home health care agencies(HHCA) were diminished and regions not having any HHCA were increased from 53% to 59%. Hospital-based home care utilization was decreased in the elderly(clients 13.4%, visits 20.9%) as well as non-elderly(clients 3.5%, visits 3.9%). It is presumed that diminished HHCAs result in decreased accessibility to hospital-based home health care for non-elderly. The clients, visits, and reimbursed cost per agency were not changed. It is presumed that small agencies were closed already. The total reimbursed cost per agency in 2009 was 121,850,000 won. Results suggest that the government has to give support to open more HHCA to increase the accessibility for non-elderly. Also, hospital-based home care services utilization has to be monitoring regularly.