• 제목/요약/키워드: Serum Characteristics

검색결과 757건 처리시간 0.028초

군부대 내 부적응 병사에서 충동성과 혈청 지질과의 상관성 (The Relationship between Serum Cholesterol and Impulsiveness in the Division of the Republic of Korean Army)

  • 김슬기;강석훈;임명호;최종혁;이병용
    • 대한불안의학회지
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    • 제8권2호
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    • pp.120-126
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    • 2012
  • Objective : Previous studies reported a correlation between the low serum cholesterol level and impulsive behaviors. In this study, we investigate an association between the serum lipid levels and psychological parameters in maladaptive soldiers in the Korean Army. Methods : A total of ninety-six maladaptive subjects and thirty-six normal controls in the Korean army were evaluated with the Korean version of Barratt Impulsiveness Scale (K-BIS), Korean version of Beck Suicidal Ideation Scale (K- BSIS), Korean version of Beck Depression Inventory (K-BDI) and Korean version of Beck Anxiety Inventory (K-BAI). Serum total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) level were measured by overnight fasting blood sampling. Results : There were no significant differences between the groups in demographic characteristics. Serum total cholesterol levels (t=-2.209, p=0.032), triglyceride levels (t=-4.593, p<0.001), and LDL levels (t=-3.753, p=0.001) of maladaptive subjects were significantly lower than those of normal controls, and maladaptive subjects had higher K-BIS scores than normal controls (t=7.542, p<0.001). Negative correlation was found between LDL levels and non-planning impulsiveness in the maladaptive subjects (r=-0.253, p=0.013). LDL levels (${\beta}=-0.258$, p=0.008) and K-BDI scores (${\beta}=0.266$, p=0.043) emerged as significant predictors for non-planning impulsiveness. Conclusion : These results suggested that LDL level was associated with non-planning impulsiveness. These findings suggested that serum cholesterol levels might be available as a biological marker of impulsiveness. However, more large samples, longitudinal biological study and psychiatric evaluations should be needed to develop a preventive intervention for maladaptive male conscripts in the Korean army.

Correlation between Cerebral Vasospasm after Subarachnoid Hemorrhage and Intercellular Adhesion Molecule-1 Levels in Serum and Cerebrospinal Fluid

  • Cheong, Jin-Hwan;Kim, Jae-Min;Bak, Koang-Hum;Kim, Choong-Hyun
    • Journal of Korean Neurosurgical Society
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    • 제38권1호
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    • pp.1-11
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    • 2005
  • Objective : The purpose of this study is to evaluate the correlation of the ICAM-l levels in serum and CSF with cerebral vasospasm in early aneurysmal subarachnoid hemorrhage [SAH] patients. Methods : A prospective analysis was performed in thirty consecutive patients who underwent early surgery for intracranial aneurysmal SAH. The serum and CSF were obtained daily through the indwelling arterial lines and intraoperative ventriculostomy, or cisternal drain for 4 consecutive days after surgery. The ICAM-1 levels in serum and CSF samples were measured via quantitative enzyme-linked immunosorbent assay. Results : The mean concentration of serum in aneurysmal SAH patients was 207.89ng/ml compared with 132.25ng/ml in controls. The mean concentration of CSF in aneurysmal SAH patients was 76.39ng/ml compared with 3.96ng/ml in controls. There were no significant differences between serum and CSF ICAM-1 level with regards to clinical characteristics in patients with aneurysmal SAH [P>0.05]. However, CSF ICAM-1 levels increased significantly in patients with vasospasm compared with those without vasospasm [P<0.05]. Conclusion : The major result of this study shows that ICAM-1 is increased in CSF after early aneurysmal SAH and that this increase in ICAM-1 has correlation with cerebral vasospasm. Further study is needed to determine whether ICAM-1 levels may be indicator in the pathogenesis of important events leading to cerebral vasospasm.

혈중 엽산농도가 대사증후군에 미치는 영향 (Effect of Serum Folic Acid Levels on Metabolic Syndrome)

  • 박윤진
    • 한국응용과학기술학회지
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    • 제40권4호
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    • pp.890-896
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    • 2023
  • 본 연구는 혈중 엽산농도와 대사증후군의 관련성을 살펴보고자 한다. 분석에 사용한 자료는 국민건강영양조사 2018년도 자료(제7기 3차)를 사용하였으며 본 연구는 만 19세 이상인 성인을 대상으로 혈중 엽산농도를 측정한 대상자 중 남자 495명, 여자 706명, 총 1,201명을 최종 분석하였다. 자료의 분석은 일반적 특성에 따른 혈중 엽산 차이는 Chi-square와 t- test로, 대사증후군 하부요인들간의 관계는 Pearson 상관관계, 혈중엽산농도와 대사증후군 지표는 로지스틱 회귀분석을 사용하였다. 본 연구 결과에 의하면 혈중 엽산농도와 대사증후군의 하부요인인 허리둘레(r=-0.113, p<0.05), 중성지방(r=-0.086, p<0.05)과 유의미한 음의 상관관계, HDL-cholesterol(r=0.086, p<0.05)은 유의미한 양의 상관관계를 보였으며 회귀분석결과 HDL-cholesterol의 경우 혈중엽산농도가 정상인 군이 낮은 군에 비하여 유의미하게 높았다(p<0.05). 따라서 본 연구를 통하여 대사증후군 예방을 위한 적절한 식습관 및 건강 교육프로그램 개발을 제안한다.

경기도 안성지역 당뇨병 환자의 유병기간에 따른 영양소 섭취 실태와 혈액성상의 임상적 특징 (A Clinical Proterties on Nutrients Intake and Serum Concentration of Diabetic Subjects by Duration in Ansung Kyunggi-do)

  • 노숙령
    • Journal of Nutrition and Health
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    • 제30권10호
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    • pp.1203-1210
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    • 1997
  • This study was performed from March to June 1994 in ANsung Medical Center. We investigated serum components of 78 diabetics in the center, in addition to the nutrient intake status and anthrophometric status of 60 diabetics among them. We separated the latter into 2 groups(ⅰ) less tan 5 years of diabetic duration and ⅱ) more than 6 years of diabetic duration) and analyzed the clinical characteristics of each group. The results are as follows : \circled1 The average ages of male and female subjects were 57.1 and 58.9 years, respectively. The average diabetic duration of male subjects was 4.8 years and that of female subjects was 5.9 . The major occupational field of both male and female subjects was agriculture(33.3%, 36.1%). 50% of male and 75% of female subject's monthly incomes were less than 600, 000 won and 75% of male and 94.4% of female subjects had weekly food expense less than 40, 000 won. The nutrient intake status of the subjects was lower than RDA on the whole. There was no big differences between 2 the male groups of different diabetic duration , but calorie, protein , fat carbohydrate, phosphorus, iron and Vit B$_1$intakes of the above 6 year female group were appearently higher than those of the under 5 year female group (p<0.05). There were different intake tendencies between male and female subjects . For females. the longer the diabetic duration, the less intakes of calorie, protein , fat carbohydrate, phosphorus, iron Vit B$_1$, Vit B$_2$, and niacin were observed. Furthermore, the longer the diabetic duration in females , the more intakes of energy and nutrients, except Vit C were observed. Fasting blood glucose levels were 155mg/dl and 164mg/dl and Postprandial glucose levels were 242mg/dl and 247mg/dl for males and females respectively. Hb of both males and females , and Ht of males met the lower limit of normal status, The serum TG level was higher than normal , so that they seemed to suffer from hyperlipidemia ; their high HbAIC status indicated that the management of diabetes mellitus was poor. The total protein level of female subject was higher when compared with that of males(p<0.05). All subjects blood pressure were higher than normal , and the longer the diabetic duration, the higher was the blood pressure. The serum HDL-cholesterol levels of the above 6 year group male subjects were lower(p<0.05) than those of the under 5 year male group subjects, and the former group's systolic and diastolic blood pressures were higher than those of the latter(p<0.05). Levels of serum total protein, albumin and TG of the above 6 year female group were lower than those of the under 5 year female group(p<0.05). As the diabetic duration was extended, HDL-cholesterol and LDL-cholesterol levels showed a tendency to increase, while Hb, Ht, total protein, albumin, and A/G, which represent the nutrients state of iron and protein, were inclined to decrease. This result showed that serum lipid components went bad. To summarize the results, the longer the diabetic duration, the worse were the male subjects nutrient intake status, but those of the female subjects were good. With respect to serum components and serum lipid subjects Fe, protein, nutrition status and serum lipid component got worse as the diabetic duration was extended , implying the possibility of diabetes mellitus complication grows.

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Serum IL-33 as a Diagnostic and Prognostic Marker in Non-small Cell Lung Cancer

  • Hu, Liang-An;Fu, Yu;Zhang, Dan-Ni;Zhang, Jie
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권4호
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    • pp.2563-2566
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    • 2013
  • Background: Interleukin-33 (IL-33) has recently been implicated in tumor immunity. The aim of this study was to explore the clinical role of serum IL-33 in patients with non-small-cell lung cancer (NSCLC). Methods: Sera collected from 250 healthy volunteers (HV), 256 patients with benign lung diseases (BLD) and 262 NSCLC cases were subjected to IL-33 ELISA and relationships between serum IL-33 and clinical characteristics were evaluated. Results: Circulating IL-33 levels were higher in the NSCLC group in comparison with the HV and BLD groups (p<0.001). Using a cut-off level 68 pg/ml (95% specificity in the HV group), IL-33 showed a good diagnostic performance for NSCLC. Multivariate survival analysis indicated that serum IL-33 was an independent prognostic factor in the entire NSCLC group [hazards ratio (HR) = 0.64 for low versus high IL-33 levels, 95% confidence interval (CI) 0.50-0.82; p<0.001] and in 165 selected patients with locally advanced or metastatic disease receiving chemoradiotherapy or chemotherapy (HR 0.70, 95% CI 0.52-0.94; p=0.013). Conclusions: IL-33 is a promising potential diagnostic and prognostic marker in NSCLC, independent of the therapeutic intervention.

정상콜레스테롤혈증과 고콜레스테롤혈증을 가진 폐경 후 여성의 신체적, 환경적 요인과 식행동 비교 (Comparisons of Anthropometric and Environmental Factors, and Food Behaviors of Normocholesterolemia and Hypercholesterolemia in the Postmenopausal Women)

  • 김상연
    • Journal of Nutrition and Health
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    • 제32권6호
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    • pp.713-725
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    • 1999
  • Women have a greater incidence of coronary heart disease(CHD) after menopause. It relates to hormone imbalance-induced changes in known CHD risk factors, especially hyperlipidemia. Accordingly, once women are diagnosed, the rate of morbidity and mortality is greater than for men. Thus, preventive strategies are critical to improve the quality oflife in the later years for women. The purpose of ths study was to explore the difference of anthropometric, environmental factors and food behaviors between normocholesterolemia and hypercholesterolemia within postmenopausal women. The subjects were classified as normocholesterolemia and hypercholesterolemia based on the Guideline for Korean Hyperlipidemia. The results obtained are summarized as follows. The distributions of general characteristics such as age, family income, occupation status, age at menarche, and menopausal period were not significantly different between the normocholesterolemia group and hypercholesterolemia group. The anthropometric factors such as body mass index(BMI) and waist hip ratio(WHR) were not significantly different between the normocholesteroemia group and the hypercholesterolemia group but odds ratio of hypercholesterolemia group was higher than that of normocholesterolemia but not significant. Aerobic activity more than 1hours/day was significantly related to low serum cholesterol concentration. Eating behaviors related to regular meal time, regular breakfast habit, and slow meal speed were related to low serum cholesterol concentration. Eating the chicken without skin was significantly related to low serum cholesterol concentration. Our data indicate that desirable eating habit, aerobic activity more than 1hr/day are important factors of serum cholesterol concentrations in postmenopausal women. The result of this study provide information that is important in designing appropriate dietary guidelines for hypercholesterolemia in postmenopausal women.

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다공성 고분자 마이크로겔의 Bovine Serum Albumin 단백질의 흡착평형 (Adsorption Equilibrium of Bovine Serum Albumin Protein on Porous Polymer Microgels)

  • 김공수;강석호
    • 공업화학
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    • 제9권2호
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    • pp.311-316
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    • 1998
  • 물리 화학적인 특성이 다른 다공성 고분자 마이크로겔에 대한 bovine serum albumin (BSA-protein) 단백질의 흡착평형 특성을 연구하였다. 수용액 속에서 고분자와 단백질사이의 소수성 상호작용에 의하여 폴리부틸메타크릴레이트 (PBMA) 마이크로겔이 폴리비닐피리딘 (PVP)과 폴리아크릴로니트릴 (PAN) 마이크로겔보다 높은 흡착특성을 나타내었으며, PBMA 마이크로겔이 PVP와 PAN 마이크로겔보다 비가역적으로 흡착평형 특성을 나타내었다. 그러므로 고분자 마이크로겔의 물리적인 특성과 단백질-고분자 마이크로겔 사이의 정전기적 인력보다는 소수성 상호작용이 단백질의 흡착특성에 중요한 역할을 하고 있음을 알 수 있다. 또한 PBMA, PVP 및 PAN 마이크로겔 모두 Freundlich 흡착 등온식보다는 Langmuir 흡착 등온식에 잘 적용되었다.

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Sex-specific relationships between alcohol consumption and vitamin D levels: The Korea National Health and Nutrition Examination Survey 2009

  • Lee, Ka-Young
    • Nutrition Research and Practice
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    • 제6권1호
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    • pp.86-90
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    • 2012
  • This study assessed the association between vitamin D sufficiency (serum 25(OH)D ${\geq}30ng/mL$) and alcohol consumption using data from the Korea National Health and Nutrition Examination Survey conducted in 2009. The following characteristics were obtained in 7,010 Korean participants ${\geq}19$-years-of-age: serum 25(OH)D level, alcohol consumption (drinking frequency, drinking number of alcoholic beverages on a typical occasion, average daily-alcohol intake), and potential confounders (age, residence, housing status, occupation, total fat and lean mass, smoking, physical activity, history of liver diseases, liver function, and daily intake of energy, protein, and calcium). After adjusting for confounders, vitamin D sufficiency in men was significantly associated with drinking frequency, number of alcoholic drinks consumed, and average daily alcohol intake; odds ratio of 1.21-1.72, 2.17-3.04, and 2.27-3.09, respectively. Increase in the three alcohol drinking-related behaviors was also linearly associated with increase in serum 25(OH)D level in men. By comparison, there was no significant association between alcohol intake and serum 25(OH)D level in women. The positive association between vitamin D sufficiency and alcohol consumption was evident only in Korean men.

Clinical, Hematological, and Biochemical Alterations in Olive Flounder Paralichthys olivaceus Following Experimental Infection by Vibrio scophthalmi

  • Qiao, Guo;Park, Soo Il;Xu, De-Hai
    • Fisheries and Aquatic Sciences
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    • 제15권3호
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    • pp.233-239
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    • 2012
  • Hematological analysis can provide crucial information for monitoring the health of fish. However, there is no current information available regarding hematological changes in olive flounder following infection by Vibrio scophthalmi. In this study, hematological and biochemical alterations were determined in olive flounder infected by the high virulence strain (HVS) and low virulence strain (LVS) of V. scophthalmi. Survival in serum, skin mucus, and macrophages of olive flounder was also compared between the HVS and LVS. The results demonstrated that the hematocrit value in infected fish declined from 23.4% at 0 h to 18.0% at 168 h post infection. The total protein concentration in fish infected with the HVS was significantly higher than in fish infected with the LVS and a non-infected control. Lysozyme activity was significantly different between infected and control fish. The HVS survived in serum and cell numbers increased substantially, while cell numbers of the LVS in serum decreased. These changes in hematological characteristics in fish infected by V. scophthalmi can be used as an effective and sensitive index to monitor the physiological and pathological conditions of fish. The survival and reproduction of V. scophthalmi in host serum, skin mucus, and macrophages play a major role in systemic infection and can serve as a virulence indicator for different strains.

Effects of Selection by Serum IGF-I Concentration in Korean Native Ogol Chicken

  • Kim, D. H.;Kim, M. H.;W. J. Kang;D. S. Seo;Y. Ko
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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    • pp.20-20
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    • 2003
  • Phenotypic characteristics and genetic markers in livestock have been utilized for improvement of the economic traits including egg productivity. Korean Native Ogol Chicken (KNOC) has low egg productivity compared to White Leghorn. Therefore, in this study, serum IGF-I concentration and number of egg production were used as selection markers to improve egg productivity. KNOCs were divided into three groups showing high IGF-I concentration (IGF-I high), high egg production (EP high), and IGF-I/EP high groups. Blood was collected every 10 weeks, and serum concentrations of IGF-I, estradiol (E2), and progesterone (P4) were measured by radioimmunoassay. In comparison of three groups in each generation, the highest increment of egg production was detected in the IGF-I/EP high group from 20 weeks till 40 weeks, and the IGF-I high group also showed the significant increment of egg production after 50 weeks. Interestingly, there were the increase of egg production and decrease of periods in sexual maturity in the second and third generation selected by serum IGF-I concentration, while egg weight and body weight decreased during experimental period. In conclusion, the present study suggest the possibility of IGF-I as a selection marker to improve the egg productivity of KNOC.

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