• International Journal of Industrial Entomology and Biomaterials
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• 제46권1호
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• pp.9-15
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• 2023

Recently, a silkworm strain (tentatively named Sericinjam) producing 100% sericin cocoons has been studied in South Korea. In this preliminary study, the crystallinity, mechanical properties, and dissolution conditions of sericin from Sericinjam cocoons were examined. The Sericinjam cocoon could be dissolved in water at high temperature (120℃) and high pressure (HTHP method) in an autoclave and in a CaCl₂/H₂O/EtOH mixture (ternary solvent method), resulting in 82% and 97% dissolution after 30 min, respectively. The solution viscosity of the silk sericin formic acid (SSFA) solution obtained from sericin extracted using the ternary solvent method was higher than that obtained using the HTHP method; however, SSFA solutions obtained from sericin extracted from conventional Baekokjam cocoons yielded a higher solution viscosity. The crystallinity and breaking strength of the sericin film from Sericinjam cocoons were slightly lower, respectively, than those from Baekokjam cocoons. In contrast, the elongation at break of the Sericinjam sericin film obtained using the HTHP method was higher than that of the Baekokjam sericin film.

• International Journal of Industrial Entomology and Biomaterials
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• 제19권2호
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• pp.255-258
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• 2009

Structure and Properties of sericinjam sericin extracted was investigated using SDS-PAGE electrophoresis, UV, CD, and DSC. The molecular weight and its distribution of sericinjam sericin showed broad tailing pattern. Circular dichlroism spectra showed that the structure of sericinjam sericin in solution was different with domestic one. However, differential thermal calorimetric properties are similar to each other.

• International Journal of Industrial Entomology and Biomaterials
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• 제18권2호
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• pp.121-124
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• 2009

We investigated sericin extracted from sericinjam, which was inbred at National Academy of Agricultural Science, Suwon, Korea. Sericinjam sericin is composed of 5 fractions: 250 kDa, 120 kDa, 90 kDa, 70 kDa and 40 kDa. Amino acid analysis showed that the major amino acids of sericinjam sericin were Ser, Gly, Asp, Glu, Thr and Ala. Infrared spectra showed that sericinjam sericin has $\beta$-sheet structure. Thermal property of sericin was investigated using DSC and then they showed characteristic degradation peak at around $215{\sim}240^{\circ}C$.

• 대한화장품학회지
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• 제39권1호
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• pp.9-17
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• 2013

본 논문에서는 세리신잠 실샘 가수분해물(Sericinjam Gland Hydrolysate: SJGH)을 이용하여 진피 섬유아세포에서 항산화 및 항노화 연구를 진행하였다. SJGH는 사람 섬유아세포에서 고농도의 과산화수소에 의한 세포사멸과 세포 내 산화 증가를 효과적으로 방어하였다. 또한 SJGH는 저농도의 과산화수소에 의한 섬유아세포의 SA-${\beta}$-Gal 발현과 MMP-1의 발현 증가를 억제하였고, 반대로 프로콜라겐 I의 생합성은 증가시켰다. 이러한 결과를 통해 SJGH의 항산화 및 항노화 효과가 우수함을 확인하였으며, SJGH가 항노화 화장품의 우수한 소재가 될 수 있음을 보여준다.