• Journal of Microbiology and Biotechnology
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• 제17권6호
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• pp.960-967
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• 2007

The co-immobilization of Aspergillus niger glucose oxidase (GOD) with bovine liver catalase (CAT) onto florisil (magnesium silicate-based porous carrier) was investigated to improve the catalytic efficiency of GOD against $H_2O2$ inactivation. The effect of the amount of bound CAT on the GOD activity was also studied for 12 different initial combinations of GOD and CAT, using simultaneous and sequential coupling. The sequentially co-immobilized GOD-CAT showed a higher efficiency than the simultaneously co-immobilized GOD-CAT in terms of the GOD activity and economic costs. The highest activity was shown by the sequentially co-immobilized GOD-CAT when the initial amounts of GOD and CAT were 10 mg and 5 mg per gram of carrier. The optimum pH, buffer concentration, and temperature for GOD activity for the same co-immobilized GOD-CAT sample were then determined as pH 6.5, 50 mM, and $30^{\circ}C$, respectively. When compared with the individually immobilized GOD, the catalytic activity of the co-immobilized GOD-CAT was 70% higher, plus the reusability was more than two-fold. The storage stability of the co-immobilized GOD-CAT was also found to be higher than that of the free form at both $5^{\circ}C\;and\;25^{\circ}C$. The increased GOD activity and reusability resulting from the co-immobilization process may have been due to CAT protecting GOD from inactivation by $H_2O2$ and supplying additional $O_2$ to the reaction system.

• 대한의용생체공학회:의공학회지
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• 제27권6호
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• pp.343-350
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• 2006

Medical magnetic stimulator generates strong magnetic field pulses. Clinical applications of the magnetic pulse are the stimulation of nervous system and the contraction of muscle. The unique source of the strong magnetic pulse is a capacitor-inductor resonator and this inductor generates a strong sinusoidal magnetic pulse by discharging the capacitor with high initial voltage. Continuous muscle contraction needs sequential generation of the magnetic pulses. However, to keep the magnitude of sequential pulses identical, an expensive high-voltage power supply have to support voltage drop of the capacitor between the pulses. A protection circuit between the supply and the resonator is necessary to protect the supply from reverse current caused by capacitor voltage reversal. In this paper, a new circuit structure of the magnetic stimulator adopting a low-frequency fly-back switching is proposed. The new circuit supports sequential pulse generation and allows the reverse current without damage. Performance of the new circuit is examined and a low-cost magnetic stimulator for urinary incontinence therapy is being developed using the presented method.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1997년도 추계학술대회 논문집
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• pp.519-522
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• 1997

In this study, the collision free path planning method of the articulated manipulator using sequential search is proposed. This method is to find the joint path of the manipulator with many degrees of freedom from the distal joint to the proximal one. To do this, the initial work space of the gantry manipulator, which is a remote maintenance equipment of the radioactive environment, is defined from the condition that the distal joint configuration is determined by the posture of maintenance. Then, 2-dimensional configuration space with the obstacle area is represented and the collision free path of manipulator is searched in the configuration space. And, this method is verified using the graphic simulation in virtual workcell for the spent fuel disassembling processes. The result of this study can be effectively used in implementing the maintenance processes for the hot cell equipment and enhance the reliability of the spent fuel management.

• 전기학회논문지
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• 제65권3호
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• pp.511-519
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• 2016

This paper is proposed control algorithm for the using thyristor of the parallel dual converter for Urban railway power supply in order to return the regenerative power generated by regenerative braking in urban railway train. Conventional control algorithm of Thyristor dual converter for urban railway power supply has voltage variation within a control range of hysteresis band. The purposed control algorithm of the parallel thyristor dual converter is to maintain a constant voltage without voltage variation in accordance with variable load through the Sequential mode change. And the control algorithm need calculating optimum initial firing angle to consider magnitude of the load current slope. For this purpose, Proposed algorithm for sequential conversion mode of the dual converter was verified by applying for the simulation.

• 한국항공우주학회지
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• 제50권11호
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• pp.771-781
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• 2022

순차 컨벡스 최적화 기법을 사용한 궤적 최적화로 무인기 기초 설계 형상의 성능 분석을 수행했다. 외부 공력 모델로 설계한 비선형 궤적 최적화 문제는 볼록화와 이산화를 통해 2차 원뿔 프로그램 문제로 근사 되었다. 알고리즘의 성능 향상을 위해 제약조건을 완화한 문제의 해를 초기 궤적으로 사용했다. 근사해의 반복적인 탐색으로 하강 궤적 최적화 문제들을 분석했으며 설계 형상의 구동부 성능에 따른 최대 도달 속도를 비교했다.

• International Journal of Computer Science & Network Security
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• 제23권6호
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• pp.193-201
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• 2023

In this paper, we consider the maximum scatter traveling salesman problem (MSTSP), a travelling salesman problem (TSP) variant. The problem aims to maximize the minimum length edge in a salesman's tour that travels each city only once in a network. It is a very complicated NP-hard problem, and hence, exact solutions can be found for small sized problems only. For large-sized problems, heuristic algorithms must be applied, and genetic algorithms (GAs) are found to be very successfully to deal with such problems. So, this paper develops a hybrid GA (HGA) for solving the problem. Our proposed HGA uses sequential sampling algorithm along with 2-opt search for initial population generation, sequential constructive crossover, adaptive mutation, randomly selected one of three local search approaches, and the partially mapped crossover along with swap mutation for perturbation procedure to find better quality solution to the MSTSP. Finally, the suggested HGA is compared with a state-of-art algorithm by solving some TSPLIB symmetric instances of many sizes. Our computational experience reveals that the suggested HGA is better. Further, we provide solutions to some asymmetric TSPLIB instances of many sizes.

• 국제지역연구
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• 제18권3호
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• pp.47-66
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• 2014

본 연구는 순차적 직접투자가 단일 직접투자에 비해 창출하는 경쟁우위를 이론적으로 규명한 후 이를 실증적으로 검증하고자 했다. 이는 대(對)중국 직접투자를 시행하는 우리나라 기업들이 주로 일회성 투자에 그치지 않고 후속투자를 거쳐 중국 시장 내 생산거점을 확보하려 한다는 전략적 행동에 기반 한 것이다. 이를 이론적으로 접근하기 위해 수량경쟁모형을 구축한 후 명제들을 추출해 냈다. 미래가치를 포함 해 도출된 균형점들은 첫째, 순차적 직접투자는 모기업들의 생산을 증대시키는 효과를 발생시킬 것이고, 둘째, 일회성 투자에 그치는 경우에 비해 순차적 투자는 큰 미래가치를 창출할 수 있으며, 셋째, 대(對)중국 순차적 직접투자는 장기적으로 진행될수록 기업단위에서 보다 큰 생산효과를 거둘 수 있다는 점을 제시한다. 이는 중국시장에서의 노하우가 축적될수록 경쟁우위가 강화될 것임을 의미한다. 이러한 이론적 명제들을 검증하고자 대(對)중국 직접투자를 시행한 우리나라 모기업들을 대상으로 회귀분석을 시도했는데, 그 결과 수량경쟁 모형으로부터 도출된 명제들이 지지되었다. 주요 결과를 정리하면 첫째, 순차적 투자는 모기업의 생산력을 증대시키는 것으로 나타났고, 둘째, 중국 내 활동기간에 비례해 중국 내 총 자회사 수가 증가함을 알 수 있다. 셋째, 중국 투자 이전 해외진출경험은 대(對)중국 순차적 직접투자를 시행한 모기업의 경영성과를 유의적으로 개선시키고, 대(對)중국 순차적 직접투자가 증가할수록 모기업의 생산성이 동반상승한다.

• 한국인터넷방송통신학회논문지
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• 제17권2호
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• pp.271-277
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• 2017

현대에 들어서면서 대기오염 물질이 심각하게 국민의 건강을 위협하는 단계에 이르렀기 때문에 이에 대한 예보의 중요성은 점점 높아지고 있다. 대기질을 예보하는데 있어서 예보 모델에 입력되는 초기장은 예보의 정확성에 영향을 미치는 요소이기 때문에 신뢰도 높은 초기장을 생성하는 것이 매우 중요하며, 이때 필요한 기법 중 하나가 자료동화이다. 자료동화는 대상 지역이 넓어지고, 관측소의 수가 증가될수록 더 많은 연산이 필요하기 때문에 그 수행시간이 길어진다. 때문에 예보 규모가 커질수록 기존의 순차처리 방식으로는 빠른 처리속도를 요구하는 현업에 적용하기 어렵다. 이에 본 논문에서는 자료동화 기법 중의 하나인 크레스만 방법을 CUDA를 이용하여 실시간으로 처리할 수 있는 방법을 제안하였다. 그 결과, 제안한 CUDA를 이용한 병렬처리 방법이 최소 35배 이상 속도가 향상되었다.

• 한국항해항만학회지
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• 제29권7호
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• pp.603-609
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• 2005

This paper presents the method for developing an optimum hull form with minimum wave resistance using SQP( sequential quadratic programming) as an optimization technique. The wave resistance is evaluated by a Rankine source panel method with non-linear free surface conditions and the ITTC 1957 friction line is used to predict the frictional resistance coefficient. The geometry of the hull surface is represented and modified using NURBS(Non-Uniform Rational B-Spline) surface patches. To verify the validity of the developed program the numerical calculations for Wigley hull and Series 60 Cb=0.6 hull are performed and the results obtained after the numerical calculations are compared with the initial hulls.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 추계학술대회 논문집 전력기술부문
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• pp.252-254
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• 2007

This paper introduces the method of sequential clustering as a tool for the effective clustering of mass unit electrical systems. The interconnected network system retains information about the location of each line. With this information, this paper aims to carry out initial clustering through the transmission usage rate, compare the results of similarity measures for regional information with similarity measures for regional price, and introduce the technicalities of the clustering method. This transmission usage rate used power flow based on congestion costs and modified similarity measurements using the FCM algorithm. This paper also aims to prove the propriety of the proposed clustering method by comparing it with existing clustering methods that use the similarity measurement system. The proposed algorithm is demonstrated through the IEEE 39-bus RTS.