• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.13 no.11
• /
• pp.1149-1155
• /
• 2001

The experimental investigation on energy separation in a vortex tube has been carried out to sow the effect of inlet and outlet pressures with various working fluids(air,$O_2,\;and\; CO_2$). Those outlet pressure means cold outlet and hot outlet pressure which were set equally. The results showed that the total enthalpy variation became a maximum when the mass flow rate at the cold outlet was a half of the total mass flow rate in the vortex tube (y=0.5). The total enthalpy variation was quite affected by the pressure difference between the inlet and outlet of vortex tube when the ratio of the inlet pressure to the cold outlet pressure remained constant. Although specific enthalpy differences between the inlet and the outlet (both cold and hot outlet) did not noticeably vary with the pressure difference, the specific enthalpy difference between the inlet and cold outlet was dominantly affected by physical properties of working gases.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.3 no.1
• /
• pp.24-31
• /
• 1998

The separation and concentration of L-phenylalanine (L-Phe) using a supported liquid membrane (SLM) is investigated. A cation complex agent, di-2-ethylhexyl phosphoric acid (D2EHPA), is used as a carrier in the SLM with n-Heptane as a solvent. The reaction order and equilibrium constant in the formation reaction of L-phe-carrier complex are obtained from the extraction experiment. A mathematical model for a carrier mediated counter transport process is proposed to estimate the diffusion coefficient of L-phe-carrier complexly in the liquid membrant. Permeation experiments of L-phe using a SLM are performed under various operating conditions and optimum conditions for the transport of L-phe are obtained. Concentration of L-phe in the strip phase against its concentration is observed. Transport rate of glucose through liquid membrane is less than that of L-phe in the competitive transport of L-phe and glucose. And the existence of glucose reduced the transport rate of L-phe. The performance of separation with continuous strip phase is increased due to the dilution effect in the strip phase.

• 한국생물공학회:학술대회논문집
• /
• 2000.11a
• /
• pp.402-404
• /
• 2000

In this study, we have developed an ultrasonic separation system for plant cells and its operating conditions in terms of voltage, flow rate and concentration were examined. For plant cell, the operation of ultrasonic separator highly depended on concentration of cells. Holding capacity highly depended on flow rate in chamber. Optimum voltage was 30V in high density culture

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
• /
• 2005.10a
• /
• pp.226-227
• /
• 2005

• KEPCO Journal on Electric Power and Energy
• /
• v.5 no.3
• /
• pp.173-179
• /
• 2019

Cryogenic air separation unit produces various gases such as $N_2$, $O_2$, and Ar by liquefying air. The process also varies with diverse production conditions. The one for SNG production among them has lower efficiency compared to other air separation unit because it requires ultrapure $O_2$ with purity not lower than 99.5%. Among factors that reduce the efficiency of air separation unit, power consumption due to compress air and heat duty of double column were representatives. In this study, simulation of the air separation unit for SNG production was carry out by using ASEPN PLUS. In the results of the simulation, 18.21 kg/s of at least 99.5% pure $O_2$ was produced and 33.26 MW of power was consumed. To improve the energy efficiency of air separation unit for SNG production, the sensitivity analysis for power consumption, purities and flow rate of $N_2$, $O_2$ production in the air separation unit was performed by change of air boosting ratios. The simulated model has three types of air with different pressure levels and two air boosting ratio. The air boosting ratio means flow rate ratio of air by recompressing in the process. As increasing the first air boosting ratio, $N_2$ flow rate which has purity of 99.9 mol% over increase and $O_2$ flow rate and purity decrease. As increasing the second air boosting ratio, $N_2$ flow rate which has purity of 99.9 mol% over decreases and $O_2$ flow rate increases but the purity of $O_2$ decreases. In addition, power consumption of compressing to increase in the two cases but results of heat duty in double column were different. The heat duty in double column decreases as increasing the first air boosting ratio but increases as increasing the second air boosting ratio. According to the results of the sensitivity analysis, the optimum air boosting ratios were 0.48 and 0.50 respectively and after adjusting the air boosting ratios, power consumption decreased by approximately 7% from $0.51kWh/O_2kg$ to $0.47kWh/O_2kg$.

• Applied Chemistry for Engineering
• /
• v.20 no.1
• /
• pp.104-108
• /
• 2009

In this study, for the flow of carbon dioxide/hydrogen mixture through a tubular type Pd-Ag membrane, hydrogen partial pressure, velocity profile, and concentration profile were simulated as a function of inlet flow rate using computational fluid dynamics (CFD) technique. The simulation results indicated that the mole fraction of carbon dioxide increased slowly in the longitudinal direction as the flow rate increased. In addition, the effects of inlet flow rate and the length of membrane on hydrogen recovery were investigated. At lower flow rate and for longer membrane, the hydrogen recovery was larger.

• Korean Journal of Animal Reproduction
• /
• v.19 no.3
• /
• pp.181-189
• /
• 1995

In this study, methods on fabrication of microtool and setting of micromanipulator were examined and relationship between first polar body extrusion rate and maturation time of follicular oocyte, enulceation rae and repetition of trial, and enucleation rate and maturation period were investigated. The results are as follows: 1. Suitable outside diameter of micropipette tube was 1mm. Holding pipette with less than diameter of oocyte was fitred for manipulation, and zona dissection needle was easily operated when its sharp-point had diameter of about 8 ${\mu}{\textrm}{m}$ and length of 300${\mu}{\textrm}{m}$. The injection pipette with 20~35${\mu}{\textrm}{m}$ outside diameter was adequate for injection of blastomere into perivitelline space. 2. Separation of blastomere was effective when zona pellucida had cut with zonadissection needle and the embryo was pipetted gently with the pipette that had narrower diameter than that of embryo until separation of blastomeres had completed. 3. The extrusion rate of first polar body was 78% during 20~24% hours incubation for maturation. 4. According to repetitions of micromanipulation, the enucleation rate was increased to 85% and the time required for enucleation of a oocyte was shortened to 3 min. 5. The extrusion rate of first polar body and enucleation rate were 82 and 76% respectively, in the group of the oocytes cultured for 22 hours. However in the group cultured for 24 hours, the extrusion rate of first polar body and enucleation rate were 53 and 100% respectively.

• Journal of Aquaculture
• /
• v.18 no.3
• /
• pp.180-188
• /
• 2005

The separation performances for thirty different dimensions of a low-pressure hydrocyclone (LPH) were tested in order to obtain an optimum dimension scale for fecal solid removal from an aquaculture system. The geometric variables were considered on two inlet diameters (Di: 30 and 50 mm), five overflow diameters (Do: 30, 50, 60, 70 and 100 mm), and three cylinder lengths (Lc: 250, 345 and 442 mm), while the cylinder diameter (Dc) of 335 mm, underflow diameter (Du) of 50 mm and cone angle (${\theta}$) of $68^{\circ}$ were kept constant. A small size for carp feces was regarded as the target for the removal of solids. Spherical polystyrene particles (1.1-1.3 mm dia., ${\rho}_s=1.05g/cm^3$), which demonstrate a similar settling velocity and specific gravity to the carp feces, were used as feed. The separation performance was tested in the range of 330 to 1200 ml/s of the inflow rate. Experimental results using ANCOVA and the Tukey test (${\alpha}=0.05$) demonstrated that the separation performances of LPH were significantly affected (P<0.05) by fi, Di and Do. In contrast, there was no significant Lc effect (P>0.05) on the separation performances. The maximum separation performance was detected at dimension combinations of 30 mm of inflow diameter (Di), 50, 60 and 70 mm of overflow diameter (Do), 345 mm of cylinder length (Lc). The dimension proportions were 0.09, 1.03, 0.15-0.21 and 0.15 (or Di/Dc, Lc/Dc, Do/Dc and Du/Dc, respectively.

• Korea Journal of Hospital Management
• /
• v.8 no.1
• /
• pp.64-80
• /
• 2003

The separation policy of prescription and drug dispensing which has been implemented since the 1st of July, 2000, has brought about great changes in patients flow within the healthcare delivery system. The changes in the patients flow, in turn, resulted in the change in the distribution of financial resources among the participating entities in the healthcare delivery system: pharmacies, clinics, small hospitals, general hospitals, and teaching hospitals. The purpose of this study is to shed some light in the change in the financial performance of teaching hospitals under the separation policy that has created environmental changes such as the decrease in the number of out patients visits, the increase in the capital expenditures, the rapid increase in labor costs and so on. For the purpose, this study has compared and analyzed the balance sheets, the income statements and other operational data of three teaching hospitals located in D area. The data include two periods: before(year 1999) and after(year 2001) the implementation of the separation policy. The analysis was conducted with an emphasis on the changes in the financial ratios such as liquidity, turnover ratio, performance ratio. and capitalization ratio. The results show that the financial performances of the hospitals under study were weaker than before the implementation of the separation policy, and that, while the operating expenses have increased remarkably, there was no tendency to corresponding increase in revenue. And the result of analysis of other operational indicators also show that the performance of the hospitals is getting worse. Based on the results, this study has suggested the directions of the healthcare policies. This study suggests to improve the current model of separation of prescription and drug dispensing, to grant subsidies for the training of residents in teaching hospitals, and to lower the rate of patients' out of porket payment in teaching hospitals.

• Progress in Superconductivity and Cryogenics
• /
• v.25 no.4
• /
• pp.60-64
• /
• 2023

The manufacturing process of antibody drugs comprises two main stages: the upstream process for antibody cultivation and the downstream process for antibody extraction. The domestic bio industry has excellent technology for the upstream process. However, it relies on the technology of foreign countries to execute downstream process such as affinity chromatography. Furthermore, there are no domestic companies capable of producing the equipment for affinity chromatography. High gradient magnetic separation technology using a high temperature superconducting magnet as a novel antibody separation and purification technology is introduced to substitute for the traditional technology of affinity chromatography. A specially designed magnetic filter was equipped in the bore of the superconducting magnet enabling the continuous magnetic separation of nano-sized paramagnetic beads that can be used as affinity magnetic nano beads for antibodies. To optimize the magnetic filter that captures superparamagnetic nanoparticles effectively, various shapes and materials were examined for the magnetic filter. The result of magnetic separation experiments show that the maximum separation and recovery ratio of superparamagnetic nanoparticles are 99.2 %, and 99.07 %, respectively under magnetic field (3 T) and flow rate (600 litter/hr).