• 제목/요약/키워드: Seoul National University Hospital

검색결과 7,267건 처리시간 0.035초

Rubidium-82 심근 Dynamic PET 영상과 변형이중적분법을 이용한 국소 심근 혈류 예측 모델 (Regional Myocardial Blood Flow Estimation Model Using Rubidium-82 Dynamic Myocardial PET and Modified Double Integration Method)

  • 박용우;이재성;이태훈;곽철은;이동수;강건욱;박재형;정재민;정준기;이명철;서정돈;민병구;고창순
    • 대한의용생체공학회:학술대회논문집
    • /
    • 대한의용생체공학회 1995년도 추계학술대회
    • /
    • pp.157-158
    • /
    • 1995

  • PDF

Successful birth with preimplantation genetic diagnosis using single-cell allele-specific PCR and sequencing in a woman with hypochondroplasia due to FGFR3 mutation (c.1620C>A, p.N540K)

  • Park, Kyung Eui;Kim, Sung Ah;Kang, Moon Joo;Kim, Hee Sun;Cho, Sung Im;Yoo, Kyoung Won;Kim, So Yeon;Lee, Hye Jun;Oh, Sun Kyung;Seong, Moon-Woo;Ku, Seung-Yup;Jun, Jong Kwan;Park, Sung Sup;Choi, Young Min;Moon, Shin Yong
    • Clinical and Experimental Reproductive Medicine
    • /
    • 제40권1호
    • /
    • pp.42-46
    • /
    • 2013

  • Hypochondroplasia (HCH) is an autosomal dominant inherited skeletal dysplasia, usually caused by a heterozygous mutation in the fibroblast growth factor receptor 3 gene (FGFR3). A 27-year-old HCH woman with a history of two consecutive abortions of HCH-affected fetuses visited our clinic for preimplantation genetic diagnosis (PGD). We confirmed the mutation in the proband (FGFR3:c.1620C>A, p.N540K), and established a nested allele-specific PCR and sequence analysis for PGD using single lymphocyte cells. We performed this molecular genetic analysis to detect the presence of mutation among 20 blastomeres from 18 different embryos, and selected 9 embryos with the wild-type sequence (FGFR3:c.1620C). A successful pregnancy was achieved through a frozen-thawed cycle and resulted in the full-term birth of a normal neonate. To the best of our knowledge, this is the first report of a successful pregnancy and birth using single-cell allele-specific PCR and sequencing for PGD in an HCH patient.

  • https://doi.org/10.5653/cerm.2013.40.1.42 인용 PDF KSCI

Primary Extraskeletal Osteosarcoma in the Anterior Mediastinum: A Case Report and Review

  • Joo, Seohee;Song, Jae Won;Na, Kwon Joong;Park, Samina;Park, In Kyu;Kim, Young Tae;Kang, Chang Hyun
    • Journal of Chest Surgery
    • /
    • 제52권4호
    • /
    • pp.243-246
    • /
    • 2019

  • Extraskeletal osteosarcoma (ESOS) is a malignant soft tissue neoplasm producing osteoid, without any continuity with the bone or periosteum. Primary ESOS presenting in the mediastinum is an extremely rare, yet aggressive malignant tumor associated with a poor prognosis. We report a case of primary ESOS arising from the thymus in a 63-year-old male patient.

  • https://doi.org/10.5090/kjtcs.2019.52.4.243 인용 PDF KSCI

Solo Intracorporeal Esophagojejunostomy Reconstruction Using a Laparoscopic Scope Holder in Single-Port Laparoscopic Total Gastrectomy for Early Gastric Cancer

  • Ahn, Sang-Hoon;Son, Sang-Yong;Jung, Do Hyun;Park, Young Suk;Shin, Dong Joon;Park, Do Joong;Kim, Hyung-Ho
    • Journal of Gastric Cancer
    • /
    • 제15권2호
    • /
    • pp.132-138
    • /
    • 2015

  • Single-incision laparoscopic total gastrectomy for gastric cancer has recently been reported by Seoul National University Bundang Hospital. However, this is not a popular procedure primarily because of the technical difficulties involved in achieving consistent intracorporeal esophagojejunostomy. At Seoul National University Bundang Hospital, we recently introduced a simple, easy-to-use, low-profile laparoscopic manual scope holder that enables the maintenance of a stable field of view, the most demanding condition in single-port gastrectomy. In this technical report, we describe in detail the world's first solo single-incision laparoscopic total gastrectomy with D1+ lymph node dissection and intracorporeal esophagojejunostomy for proximal early gastric cancer.

  • https://doi.org/10.5230/jgc.2015.15.2.132 인용 PDF KSCI