• 대한생식의학회:학술대회논문집
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• 2004.11a
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• pp.85.1-85.1
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• 2004

• Proceedings of the PSK Conference
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• 2001.10a
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• pp.319.1-319.1
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• 2001

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.157-158
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• 1995

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.34 no.1
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• pp.59-59
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• 2023

• Clinical and Experimental Reproductive Medicine
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• v.40 no.1
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• pp.42-46
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• 2013

Hypochondroplasia (HCH) is an autosomal dominant inherited skeletal dysplasia, usually caused by a heterozygous mutation in the fibroblast growth factor receptor 3 gene (FGFR3). A 27-year-old HCH woman with a history of two consecutive abortions of HCH-affected fetuses visited our clinic for preimplantation genetic diagnosis (PGD). We confirmed the mutation in the proband (FGFR3:c.1620C>A, p.N540K), and established a nested allele-specific PCR and sequence analysis for PGD using single lymphocyte cells. We performed this molecular genetic analysis to detect the presence of mutation among 20 blastomeres from 18 different embryos, and selected 9 embryos with the wild-type sequence (FGFR3:c.1620C). A successful pregnancy was achieved through a frozen-thawed cycle and resulted in the full-term birth of a normal neonate. To the best of our knowledge, this is the first report of a successful pregnancy and birth using single-cell allele-specific PCR and sequencing for PGD in an HCH patient.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.11
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• pp.147-147
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• 1996

• Journal of Chest Surgery
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• v.52 no.4
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• pp.243-246
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• 2019

Extraskeletal osteosarcoma (ESOS) is a malignant soft tissue neoplasm producing osteoid, without any continuity with the bone or periosteum. Primary ESOS presenting in the mediastinum is an extremely rare, yet aggressive malignant tumor associated with a poor prognosis. We report a case of primary ESOS arising from the thymus in a 63-year-old male patient.

• Journal of Gastric Cancer
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• v.15 no.2
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• pp.132-138
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• 2015

Single-incision laparoscopic total gastrectomy for gastric cancer has recently been reported by Seoul National University Bundang Hospital. However, this is not a popular procedure primarily because of the technical difficulties involved in achieving consistent intracorporeal esophagojejunostomy. At Seoul National University Bundang Hospital, we recently introduced a simple, easy-to-use, low-profile laparoscopic manual scope holder that enables the maintenance of a stable field of view, the most demanding condition in single-port gastrectomy. In this technical report, we describe in detail the world's first solo single-incision laparoscopic total gastrectomy with D1+ lymph node dissection and intracorporeal esophagojejunostomy for proximal early gastric cancer.

• Korean Journal of Radiology
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• v.25 no.4
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• pp.403-406
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• 2024

• 대한생식의학회:학술대회논문집
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• 2007.11a
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• pp.140.1-140.1
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• 2007