• 보건행정학회지
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• 제27권2호
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• pp.128-138
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• 2017

Background: The purpose of this study is to analyze the effects of differential coinsurance policy on prescription drug coverage of outpatients by types of medical institutions. Methods: In this study, we used a sample cohort database of the National Health Insurance Service and frequency analysis and marginal logistic regression model using generalized estimating equation were used for statistical analysis. Results: The summary on the major research is followed. First, about 16% of patients who used only tertiary or general hospital due to 52 ambulatory care sensitive conditions before policy implementation moved to hospitals and clinics. However, about 57% of them still use tertiary or general hospital. Second, the factors influencing the utilization of hospitals and clinics after the implementation of the policy were gender, age, and income level. As a result, the policy is effective to reduce the medical use of outpatient mental patients in tertiary or general hospital, but the effect is not significant. Conclusion: Therefore, in order to achieve the purpose of the policy for establishing the health care delivery system, it is necessary to adjust the co-payment so as to feel the burden on the co-payment when the outpatient for 52 ambulatory care sensitive conditions is used at the tertiary or general hospital.

• 정보보호학회논문지
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• 제27권1호
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• pp.91-101
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• 2017

API(Application Program Interface) 콜 시퀀스 분석은 분석 대상 프로그램에서 API 콜 정보를 추출한 후 분석하는 기법으로 다른 기법들에 비해 대상의 행위를 특징할 수 있는 장점이 있다. 하지만 기존의 API 콜 시퀀스 분석기법은 동일한 기능을 수행하는 함수를 상이한 함수로 잘못 식별하여 분석을 수행하는 문제점이 존재한다. 본 연구에서는 API 각각을 추상화시키는 방식을 추가하여 기존의 식별 문제를 해결하고 분석 성능을 향상시키고자 한다. 그 후 분석 대상들에서 획득한 추상화된 API 콜 시퀀스에 LSH(Locality Sensitive Hashing) 기법을 적용하여 각 분석 대상들 간의 유사도를 계산하고 유사한 유형끼리 클러스터를 형성하는 과정을 수행하였다. 본 연구는 악성코드 분석 시 악성코드의 유형을 파악하는 데 요긴하게 사용할 수 있으며, 최종적으로는 해당 유형 정보를 기반으로 악성코드 분석의 정확도를 향상시키는 데 기여할 수 있다.

• 한국군사과학기술학회지
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• 제21권5호
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• pp.697-703
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• 2018

In this paper, we analyzed the operation of the ignition circuit for electronic arm and fire device(EAFD), and investigated the sensitive elements of the circuit system. For reliability analysis, the EAFD ignition circuit was modeled using the PSpice simulation tool, and the output results of the circuit were examined by changing the tolerance of each circuit element. Monte Carlo simulation was used by maintaining the values of the observed sensitive elements at ${\pm}10%$ of the original values and adjusting the values of the other components according to a random distribution. The histogram results of the output peak currents and pulse widths were represented by Weibull and Burr type XII function fittings in three cases(element values are +10 %, 0 %, -10 % of original). For the output peak currents, mean values were 1.0028, 1.0034, and 1.0050, where the variance values were calculated as 0.0398, 0.0396, and 0.0290 using the Weibull function fitting, respectively. For pulse widths, the mean values of 0.9475, 0.9907, and 1.0293 with the variance values of 0.0260, 0.0251, and 0.0238 were obtained using the Burr Type XII function fittings.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 춘계학술대회논문집
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• pp.340-343
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• 2007

In this paper, we present our method to reduce vibration of the base plate of a refrigerator by avoiding resonance between base plate and compressor operation. To verify the modes of the base plate, FE models of the base plate with free-free condition and applied boundary condition were built and validated by results from experimental modal analysis. Operating Deflection Shape analysis was applied to find the sensitive area on the base plate during compressor operation. In optimization process, Finite Difference Method - based sensitivity analysis is used to detect the most sensitive area. Finally, based on this numerical result, we will make beads on the base plate to reduce vibration of refrigerator.

• Water Engineering Research
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• 제5권3호
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• pp.133-146
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• 2004

Soil and water assessment tool (SWAT) was simulated based on the default parameters and a priori soil parameter estimation method in Bocheong watershed of Korea. The performance of the model was tested against the measured daily runoff data for 5 years between 1993 and 1997. The sensitivity analysis of SWAT model parameters was conducted to identify the most sensitive model parameters affecting the model output. The results of SWAT simulation indicate that the overall performance of SWAT in calculating daily runoff is reasonably acceptable. However, there is a problem in estimating the low flow components of streamflow since the low flow components simulated by SWAT are significantly different from the measured low flow. The sensitivity analysis with SWAT points out that soil related parameters are the most sensitive parameters affecting surface and ground water balance components and groundwater flow related parameters exhibit negligible sensitivity.

• Journal of Chest Surgery
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• 제36권11호
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• pp.852-857
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• 2003

배경: 중피종은 일반적 치료에 대하여 큰 효과가 없다고 알려져 있다. 저자들은 Adenoviral p53에 민감하게 반응하는 중피종 세포주인 염증 및 표피세포 아유형(subtype)에 adenovirus유전자 핵산전달감염(transfection)으로 중피종 치료의 새로운 방법에 대하여 평가하고자 하였다. 대상 및 방법: 두 쌍의 adenoviral PTEN와 LacZ (Ad/GT-LacZ와 Ad/GV16) 매개체(vectors)에 REN (p53 sensitive)인 중피종 세포주(methothelioma cell lines)의 형질을 도입(transduction)하였으며, 단백질 함량은 Western blotting 분석을 이용하여 측정하였다. 세포사멸은 fluorescence-activated cell sorter analysis of subdiploid populations에 의하여 평가하였으며, 세포 생존력은 XTT 분석에 의하여 결정하였다. 통계 분석은 analysis of variance와 Student t test를 이용하여 하였다. 결과: Adenoviral PTEN 유전자로 처치된 세포사는 72시간 후에 MOI of 20에서 대조군 2.5%에 비하여 REN군 32.9%로 상대적으로 높게 나타났다. 또한 REN cell에서의 전구세포사멸 단백질(proapoptotic protein)인 BAX 발현 증가를, BCL-2에서 발현 감소를 나타내었으나, BCL-XL, BAK 및 BAD 단백질은 변화가 없었다. 결론: Adenovirus PTEN을 매개로 한 BAX 발현 증가는 세포사멸을 유도하고 p53에 민감한 중피종 세포들(p53-sensitive methothelioma cells)에서 세포 생존력을 감소시킨다. 이러한 결과는 PTEN 유전자 핵산전달감염하는 것은 중피종 치료의 새로운 대안적 방법이 될 수 있다는 것을 암시한다.

• 한국의류산업학회지
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• 제11권5호
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• pp.808-817
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• 2009

The purpose of this study was to verify potential differences in group- specific external feature concerns and beauty care behaviors of Korean women in their 20's~40's depending on their narcissistic propensity. This study is to take psychological approaches to narcissistic propensity of our contemporary society, so that it can get better understanding about consumers and provide marketing data on beauty-related industry. To meet the above goals, total 400 sheets of questionnaire were distributed to subjects from March 30 to April 8, 2009. Out of 376 sheets of questionnaire collected, total 355 valid questionnaires except incomplete 21 ones were used for final data analysis. For data analysis, this study used SPSS 12.0 as statistic program to perform factor analysis, reliability test (Cronbac's ${\alpha}$ coefficient), cluster analysis, t-test, analysis of variance (ANOVA), Duncan's multiple range test and multiple regression analysis. As a result, this study could come to the following findings: First, according to cluster analysis depending upon different factors such as self-directed narcissism, others-conscious narcissism and others-sensitive narcissism, it was found that our women in 20's to 40's could fall into 4 groups, i.e. complex narcissism group, mixed narcissism group, others-sensitive narcissism group and dispirited narcissism group. Second, according to analysis on potential differences in external feature concerns among four groups depending on their narcissistic propensity, it was found that there were significant differences in all relevant factors among groups. Third, according to analysis on differences in beauty care behaviors among four groups depending upon their narcissistic propensity, it was found that there were significant differences in all relevant factors among groups. Fourth, according to analysis on potential factors of external feature concerns that may influence beauty care behaviors of complex narcissism group, it was found that those factors had significant effects on fashion-orientedness, cosmetic surgery and personality pursuit of this group. And it was also found that there were significant differences in fashion-orientedness, cosmetic surgery, makeup and hair styling of mixed narcissism group, others-sensitive narcissism group and dispirited narcissism group respectively.

• 환경영향평가
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• 제25권6호
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• pp.402-413
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• 2016

유류의 해상운송은 필수 불가결한 요소이기 때문에 이로 인한 해양 유류유출 사고는 지속적으로 발생하고 있다. 유류유출을 미연에 방지하는 시스템의 구축도 중요하지만, 불가피하게 사고가 발생하였다면 어떻게 대처할 것인가에 대한 체계적인 대안 마련이 필요하다. 지금까지는 유류유출로 인한 환경적 민감자원들에 대한 대응 및 지원 방안 연구가 주를 이루었다면, 이제는 지역 주민의 삶의 터전을 구성하는 사회 경제적 민감자원에 대한 피해 평가까지 확장하여 연구할 필요가 있다. 본 연구는 해양 유류유출로 인한 사회 경제적 민감자원 평가를 위한 일련의 분석 프레임워크를 구축하기 위한 과정으로, 우리나라의 실정에 맞는 사회 경제적 민감자원을 파악하고 지수화하는 방안을 제안한다. 기존의 민감자원 선정 사례를 정리하여 우리나라에 맞는 민감자원 선정 대안을 제시하는 것도 중요하지만 다양한 지표들 가운데 평가를 위해 실제 분석에서 가용한 데이터를 고려하여야 할 필요가 있다. 본 연구에서는 기존의 선정 대안 및 지수화, 사회영향평가 등 다양한 연구들을 기반으로 하여 사회 경제적 민감자원을 수산물 획득, 인구, 토지이용, 관리지역, 문화유산 및 관광지로 구분하였다.

• Journal of Photoscience
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• 제9권2호
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• pp.329-331
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• 2002

There is a difference in the inhibitory effects to supplemental UVB (wavelengths 280 to 320 nm) among Japanese rice (Oryza sativa L.), the cultivar Norin I is less resistant while the cultivar Sasanishiki is resistant. UVB induces photodamage in DNA. Cyclobutane pyrimidine dimer (CPD) is a major UV-induced DNA lesion. Photorepair, which is mediated by photolyase, is the major pathway in plants for repairing CPD. We have analyzed CPD induction and repair in Sasanishiki and its close relative Norin I using alkaline agarose gel electrophoresis. Norin I is deficient in CPD photoreactivation and excision, thus UV sensitivity correlates with deficient dimer repair [I]. The photorepair deficiency in Norin I results from a functionally altered photolyase with a photoflash analysis [2]. In this paper, we examined the UVB-sensitivity of several other UV-sensitive and -resistant cultivars and found that the CPD photolyase activity was deficient in UV-sensitive ones. It was also evident that there was a variation in the deduced amino acid sequences of CPD photolyases of the UV-sensitive and -resistant cultivars, whereas each deduced amino acid sequence of the UV-sensitive cultivars and of the UV-resistant ones was the same. These results suggest that the difference in the CPD photolyases of UV-sensitive and -resistant rice might be due to the structural alteration of CPD photolyase.

• 한국미생물·생명공학회지
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• 제27권1호
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• pp.8-14
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• 1999

This study was developed to evaluate the growth inhibition effects of cell wall components of Enterococcus faecalis 2B4-1 obtained from feces of neonates against tumor cell lines. Polysaccharide fraction (PS) shown sensitive growth inhibition effect in the cell wall components was isolated and characterized. In growth inhibition effects, residue fractin of whole cell was shown sensitive level of percent survival about 30% when administrated at ehe concentration of 100${\mu}$g/ml, and that was more effective than that of supernatant fraction against the tumor cell lines, SNU-1, 3LL, FARROW and HEC-1-B. Sensitive growth inhibition effects against SNU-1, FARROW and HEC-1-B were performed by whole cell (WC) fraction from Ent. faecalis 2B4-1. Cytoplasm fractin (CP) of WC was shown non-inhibition effect, however, the other part of WC, precipitate of disrupted cell (PD), was sensitive against the tumor cell line mentioned above. Followed by separation to peptidoglycan fraction (PG) and polysaccharide fraction (PS) were all sensitive which the latter was shown more sensitive percent survival than the former. Composed sugars of polysaccharide fraction were determined to D-glucose, L-rhamnose and D-glucosamine, and the rate fo composition was calculated to about 1:1:1 by the data of elemental analysis, IR, TLC and HPLC.