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Synthesis and pH-Dependent Micellization of a Novel Block Copolymer Containing s- Triazine Linkage

  • Pal Ravindra R.;Lee Doo Sung
    • Macromolecular Research
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    • v.13 no.5
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    • pp.373-384
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    • 2005
  • Novel pH-sensitive moieties containing an s-triazine ring were synthesized with sulfonamide and secondary amino groups. The synthesized pH-sensitive moieties were used for the synthesis of a pH-sensitive amphiphilic ABA triblock copolymer. The pH-sensitive triblock copolymer was composed of diblock copolymers, methoxy poly(ethylene glycol)-poly ($\varepsilon$-caprolactone-co-D,L-lactide) (MPEG-PCLA), and pH-sensitive moiety. These copolymers could be dissolved molecularly in both acidic and basic aqueous media at room temperature due to secondary amino and sulfonamide groups. The synthesized s-triazine rings containing pH-sensitive compounds were characterized by ${^1}H-NMR,\;{^13}C-NMR$, and LC/MSD spectral data. The synthesized diblock and triblock copolymers were also characterized by ${^1}H-NMR$ and GPC analyses. The critical micelle concentrations at various pH conditions were determined by fluorescence technique using pyrene as a probe. Furthermore, the micellization and demicellization study of the triblock copolymer was done with pH-sensitive groups. The sensitivity towards pH change was further established by acid-base titration.

Does National Distance Affect Different Industries in Different Ways? A Test of the Ghemawat CAGE Model

  • Kim, Hak Cho;Kwon, Jong-Wook;Zhou, Zhibin;Heo, Ji Hyun
    • Journal of Korea Trade
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    • v.23 no.7
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    • pp.13-33
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    • 2019
  • Purpose - This study empirically investigated whether national distances (Cultural, Administrative, Geographic and Economic distance) have different effects on industries in different ways. Design/methodology - The empirical model utilized industry level export trade data to examine the differentiated effects of each national distance. By using direct measurement and covering 75 countries, this paper analyzes the effect of distances in different industries. More specifically, this study classified the industries into a more-sensitive/less-sensitive scale. Findings - The empirical results showed the complicated impacts of national distances on trade. Trade in industries that are more sensitive to cultural and administrative distances was not decreased as greatly as trade in industries that are less sensitive to cultural and administrative distances. Also, industries that are more sensitive to geographic distance showed a stronger negative impact on trade than less sensitive industries. Lastly, economic distance decreased trade for industries that are more sensitive to economic distance, while economic distance did not significantly increase trade for industries that are less sensitive to economic distance. Originality/value - As the first study to empirically find out whether national distance has different effects on industries, this study updated the measurements of national distance.

Secure Training Support Vector Machine with Partial Sensitive Part

  • Park, Saerom
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.4
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    • pp.1-9
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    • 2021
  • In this paper, we propose a training algorithm of support vector machine (SVM) with a sensitive variable. Although machine learning models enable automatic decision making in the real world applications, regulations prohibit sensitive information from being used to protect privacy. In particular, the privacy protection of the legally protected attributes such as race, gender, and disability is compulsory. We present an efficient least square SVM (LSSVM) training algorithm using a fully homomorphic encryption (FHE) to protect a partial sensitive attribute. Our framework posits that data owner has both non-sensitive attributes and a sensitive attribute while machine learning service provider (MLSP) can get non-sensitive attributes and an encrypted sensitive attribute. As a result, data owner can obtain the encrypted model parameters without exposing their sensitive information to MLSP. In the inference phase, both non-sensitive attributes and a sensitive attribute are encrypted, and all computations should be conducted on encrypted domain. Through the experiments on real data, we identify that our proposed method enables to implement privacy-preserving sensitive LSSVM with FHE that has comparable performance with the original LSSVM algorithm. In addition, we demonstrate that the efficient sensitive LSSVM with FHE significantly improves the computational cost with a small degradation of performance.

Cross Talk among Pyroelectric Sensitive Elements in Thermal Imaging Device

  • Bang Jung Ho;Yoon Yung Sup
    • Proceedings of the IEEK Conference
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    • 2004.08c
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    • pp.780-783
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    • 2004
  • The two-dimensional modeling of the non-stationary thermal state and voltage responsivity of the sensitive elements usually used in solid-state pyroelectric focal plane arrays are presented. Temperature distributions under periodical thermal excitation and the response of the thermal imaging device, which is composed of the pyroelectric sensitive elements mounted on a single silicon substrate, are numerically calculated. The sensitive element consists of a covering metal layer, infrared polymer absorber, front metal contact, sensitive pyroelectric element, the interconnecting column and the bulk silicon readout. The results of the numerical modeling show that the thermal crosstalk between sensitive elements to be critical especially at low frequency (f < 10Hz) of periodically modulated light. It is also shown that the use of our models gives the possibility to improve the design, operating regimes and sensitivity of the device.

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A Conditional Indirect Survey Method

  • Lee, Gi-Sung;Hong, Ki-Hak;Son, Chang-Kyoon;Nam, Ki-Seong
    • Journal of the Korean Data and Information Science Society
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    • v.13 no.1
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    • pp.35-45
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    • 2002
  • For improving the quality of survey dat a of sensitive character, we suggest a conditional in direct survey method. In th at method, only the respondents who answer directly to the less sensitive question respond indirectly to the more sensitive one by using the one sample unrelated question randomized response technique with the known $\pi_y$, the true proportion of unrelated group Y. We extend it to two sample method when $\pi_y$ is unknown. We also consider the case that people who possess less sensitive character answer untruthfully. Finally we compare our method with the methods of Greenberg et al. and Carr et al..

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A Novel Behavior, Bang-Sensitive Paralysis, Associated With The shibire Locus of Drosophila melanogaster

  • 김윤택
    • Environmental Mutagens and Carcinogens
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    • v.10 no.2
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    • pp.93-106
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    • 1990
  • The Drosophila temperature-sensitive mutant shibire (shi) is paralyzed at restrictive temperature by a reversible block in synaptic transmission. To explore the functional relationship among shi gene products, viability and temperature-sensitive paralytic behavior were quantitaively analyzed for four shi alleles, shi$^{ts1}$, shi$^{ts2}$, shi$^{ts4}$, and shi$^{ST139}$, and their heteroallelic combinations. The hemizygous combination of shi alleles over deficiency was not completely lethal. shi$^{ts2}$ exhibited distinctively higher viability than other alleles. A novel behavior, bang sensitivity, was also found in shi/Df(1). This bang-sensitive paralytic behavior was compared with that of the typical bang-sensitive mutant flies. Heterozygotes, shi/+, are more severe in temperature sensitivity than deficiency hemizygotes, Df(1)/+. Heteroallelic combinations of shi were less sensitive to high temperature than homozygotes. Among all allelic combinations, shi$^{ts2}$/shi$^{ts4}$ showed an unexpected extreme reduction in temperature sensitivity. The results of allelic interactions among 4 shi alleles suggest that the shi mutations examined behave as antimorphic alleles and that the gene product of shi are likely to function in multimeric forms.

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The Study of Gas Sensor Using Rheological Properties of Polymeric Sensitive LB Films (고분자감응성 LB막의 유변학적인 특성을 이용한 가스센서 연구)

  • 강현욱;김정명;권영수
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1997.04a
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    • pp.198-201
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    • 1997
  • The new system for identification of organic vapours and analysis method of mechanism between organic vapours and sensitive materials were attempted using the resonant resistance and resonant frequency of Quartz Crystal Analyzer (Q. C. A.). The resonant resistance shift means rheological changes in sensitive LB films occurred by the adsorption of organic vapours, while the resonant frequency shift represent the mass of organic vapour loaded in or on the sensitive LB films. It is thought that we can obtain more accurate response mechanism of organic vapour using the resonant frequency and resonant resistance diagram. The polymeric sensitive material were quantitively depositied using the LB method. In the experimental results, the adsorption behavior of organic vapour response can be decided by two type ; surface adsorption and penetration into sensitive material. Organic vapours had different positions in the Frequency-Resistance (F-R) diagram as to the kinds and concentrations of organic vapours. Thus F-R diagram can be applied to the development of one channel gas sensing system using the Quartz Crystal Analyzer.

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The Criteria, Procedure, and Classification of Traffic-Sensitive and Non-Traffic-Sensitive Components: A Case of CDMA Mobile System

  • Kim, Moon-Soo
    • ETRI Journal
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    • v.28 no.6
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    • pp.777-786
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    • 2006
  • Since the introduction of competition in the telecommunication market due to the growth of the interconnection between heterogeneous networks, particularly fixed and mobile networks, the interconnection charge based on traffic-sensitive (TS) and non-traffic-sensitive (NTS) costs has become more important. Although there have been many studies of the public switched telephone network (PSTN), previous studies of TS and NTS costs in mobile networks are very few. In this paper, as a pilot study, we propose three criteria and a procedure for the classification of TS and NTS costs based on mobile systems. The three criteria are the following: function type, investment requirement, and main exhaust driver. Moreover, for a CDMA mobile system, strongly TS, strongly NTS, and mixed components are classified by the proposed criteria and procedure. The proposed criteria, procedure, and classification can provide a systematic and useful guideline to decide the scope of mobile facilities and to determine the terminating cost on mobile networks from fixed networks.

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Average performance of risk-sensitive controlled orbiting satellite and three-degree-of-freedom structure

  • Won, Chang-Hee
    • 제어로봇시스템학회:학술대회논문집
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    • 1995.10a
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    • pp.444-447
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    • 1995
  • The satellite in a circular orbit about a planet with disturbances and a three-degree-of-freedom (3DOF) structure under seismic excitations are modeled by the linear stochastic differential equations. Then the risk-sensitive optimal control method is applied to those equations. The mean and the variance of the cost function varies with respect to the risk-sensitivity parameter, .gamma.$_{RS}$ . For a particular risk-sensitivity parameter value, risk-sensitive control reduces to LQG control. Furthermore, the derivation of the mean square value of the state and control action are given for a finite-horizon full-state-feedback risk-sensitive control system. The risk-sensitive controller outperforms a classical LQG controller in the mean square sense of the state and the control action.

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Characterization of Voltage-Sensitive Calcium Channels and Insulin Secretion and the effect of 4,4'-Dichlorobiphenyl in RINm5f cells

  • Lee, Ihn-Soon;Hur, Eun-Mi;Sungkwon Chung;Kim, Kyong-Tai
    • Proceedings of the Korean Biophysical Society Conference
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    • 2001.06a
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    • pp.47-47
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    • 2001
  • Opening of $Ca^{2+}$ -channels represents the final common pathway for insulin secretion in pancreatic beta-cells and related cell lines. We investigated voltage-sensitive calcium channels (VSCCs) and insulin secretion in RINm5F, an insulinoma cell line derived from rat pancreatic beta-cells. Several types of VSCCs were identified in RINm5f cells: dihydropyridine-sensitive L-type, $\omega$-conotoxin GVIA-sensitive N-type, $\omega$-agatoxin IVA-sensitive P-type channels, and $\omega$-conotoxin MVIIC sensitive Q-type channels.(omitted)

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