• Transactions of the Korean Society of Mechanical Engineers
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• v.13 no.4
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• pp.703-707
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• 1989

The ignition of solid particle under strong convective heating has been investigated by applying an asymptotic analysis to a semi-infinite body for varying values of gas recovery temperature and convective heat transfer coefficient. It was found that if the scale of the reaction zone is much smaller than the characteristic length of the body size, then infinite body theory can be used to estimate the ignition delay time. Furthermore, the convective heat transfer coefficient was found to have more influence on predicting the ignition delay times of particle exposed to an incident shock wave rather than the gas recovery temperature.

• Journal of Pharmaceutical Investigation
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• v.41 no.2
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• pp.75-82
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• 2011

LB71350 is an HIV protease inhibitor with poor aqueous solubility and extensive first pass effect. The purpose of the present study was to test the feasibility of solid dosage form of LB71350 with improved bioavailability utilizing solid dispersion. Three different compositions with varying ratio of (LB71350: Gelucire 44/14: Tween 20) were studied. Capsule filling of these solid dispersion compositions was tested using a semi-automatic capsule filling system. Oral bioavailability in dog was tested. Chemical and physical stability at 4, 25 and $40^{\circ}C$ was monitored by HPLC assay, dissolution test, powder XRD and microscopy. The capsule filling system yielded uniform products of drug loading up to 10%. Oral bioavailability in dog was improved compared to the aqueous suspension of crystalline LB71350. Capsules were chemically stable for up to 6 months at $40^{\circ}C$. However, there were temperature and composition dependent physical changes. Decrease in dissolution rates after storage at $40^{\circ}C$ was due to the polymorphic change. In conclusion, manufacturing process, bioavailability, and physico-chemical stability have been considered to propose a solid dispersion capsule formulation for the HIV protease inhibitor with poor physico-chemical properties. A new less soluble crystalline form identified during the physical stability test warrants further study.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2012.05a
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• pp.1011-1012
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• 2012

• Journal of Chest Surgery
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• v.22 no.1
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• pp.146-150
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• 1989

Dysphagia is common in patients with cancer of the esophagus. The rate of resectability of the lesion is low, and the majority of the patients require palliation to relieve the dysphagia. Celestin tube intubation was performed in patients with unresectable carcinoma of the esophagus, of one with malignant bronchoesophageal fistula. Dysphagia and respiratory symptoms were relieved and the patients became able to eat semi-solid food and fully ambulatory.

• Proceedings of the Materials Research Society of Korea Conference
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• 2001.11a
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• pp.113-113
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• 2001

• The Korean Journal of Food And Nutrition
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• v.13 no.5
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• pp.465-476
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• 2000

This study was performed to investigate the frequency of dairy beverage consumption and factors which affect the dairy beverage consumption of women. The subjects were 1,012 females living in Seoul. They preferred milk, yakult. flavored milk, liquid yogurt, semi-solid yogurt, and low fat milk in order of frequency. The consumption of the dairy beverage was not related to season. The respondents knew that the dairy beverages were nutritious and good for their health. More than fifty percent of them answered that dairy beverages tasted good. The consumption of milk and yakult were related with their occupation, habitual aspect, and practical factors. The consumption of liquid yogurt was affected by their family income, habitual aspect, practical factors and familarity with that beverage. The consumption of semi-solid yogurt was affected by their family income, health status, habitual aspect, and practical factors. The consumption of most beverages were affected by the recognition of those beverages rather than by socio-demographic factors. In order to enough drink dairy beverage, nutritional education messages should encourage consumption of dairy beverages. Policies that make students access dairy beverages at school should be promoted.

• Journal of the Korean Society for Heat Treatment
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• v.26 no.4
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• pp.165-172
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• 2013

In the present study, the microstructure and solution treatment response of Al-Zn-Mg alloys bars by thixo-extrusion was investigated. The alloy bars were solution treated at 400, 430, 460 and $490^{\circ}C$ for various times. In order to examine the microstructures and phase analysis of the samples after solution treatment, it was performed by optical and scanning electron microscopy. And, Vickers hardness and electrical conductivity was measured on the solution treated samples for each condition to investigate the solution treatment response of extruded bars during solution treatment. The results show that the optimum solution heat treatment conditions of thixo-extruded Al-Zn-Mg alloy for minimization of the grain growth and degradation promotion of the second phase is a temperature of $460^{\circ}C$ and holding time of 0.5 to 2 h.

• Journal of Korea Foundry Society
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• v.18 no.6
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• pp.541-549
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• 1998

Microstructural characteristics of hypereutectic Al-Si alloys during reheating at semi-solid temperature have been investigated. The size and morphology of primary Si particles in wedge-type mold-cast ingot has been compared with hot-rolled sheet and Si particulate reinforced Al composite. Effects of P and Sr addition on the morphological changes of primary Si particles have been also investigated. Observation of the solidification microstructures of the wedge-type mold-cast ingot at different cooling rates showed that alloying elements such as P and Sr affect the morphology of Si particles, especially in the area solidified at a slow cooling rate. Negligible change in the size of primary crystals was observed after reheating experiment, but ${\alpha}-halo$ formed around the Si particles and fine particles of Si precipitated in the surrounding area of the Si particles. In addition, there seemed to be no coarsening with increasing of holding time and the region of ${\alpha}-halo$ being decreased. Nucleation and recrystallization was accelerated with addition of alloying elements during hot rolling resulting in a decrease of primary Si particle size. In the case of extruded specimens, morphological change of primary Si particles was not observed after reheating. No ${\alpha}-halo$ formation was observed in Si reinforced Al composite because of the oxide film formed on the Si particles which acted as a diffusion barrier between substrate and the primary Si particles.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1997.10a
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• pp.1028-1031
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• 1997

The SS (Semi-solid) diecasters usually cany out the SS d~ecastmg experiments before producing new products. At the SS diecasting stages, the runner-gate part is always repeatedly corrected, which leads to a lengthened processing time and increased processing cost. The SS diecasting die design should consider component system factors. such as runner, gate, biscuit, overflow and airvent. A large amount of experience is essential in manual assessment and if the design is defective, much time and a great deal of efforts will be wasted in the modification of the d~e. Thus human negligence should be minimized. In this study, die design system for SS diecasting process has been developed to present algonthm of die design, especially runner-gate system. In addition, specific rules and equations for runner-gate system have been presented to avoid too many trials and errors with expensive equipment. It is possible for engineers to be efficient die design of SS diecasting and it will result in reduction of expense and time to be required. And we developed CAD system for SS diecasting die design by AutoLISP language under AutoCAD using proposed algorithm and the database. In addition, we developed the vector analysis program for filling pattern of SS metals.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 1999.03b
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• pp.199-202
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• 1999

Many processing times for fabricating complex shaped parts by near net shape process such as thixoforming or semi-solid forming, are required due to the time for die design, induction heating and forming process. Therefore, for the thixoforming process, multi-capacity induction heating process is very important due to the reduction of the processing time and cost. It is indispensable to adopt a power-time heating pattern which manages to conciliate complete eutectic melting at the core with limited overheating at the periphery. The total reheating time is thus dependent on billet diameter; in inches$(pm20%)$. Typically, high frequency is used for the rapid reheating of the billet to the eutectic temperature range and low frequency for the remelting of the desired fraction of liquid and for the radial homogeneization of the liquid fraction. So in this study, the multi-capacity induction heating conditions of ALTHIX 86s alloy to reduce the processing time and cost would be proposed. The suitability of multi-capacity induction heating conditions would be verified through the comparison to Garat's data.