• Child Health Nursing Research
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• 제20권1호
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• pp.30-38
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• 2014

목적 본 연구의 목적은 학령전기 아동 어머니의 아동 신체활동 지지의 수준을 파악하고, 아동 신체활동 지지에 대한 영향요인을 확인하는 것이다. 방법 자가보고식 설문조사 방법을 적용하였으며, 대전 소재 3개 유치원에 다니는 만 3-6세 학령전기 아동의 어머니의 156명의 자료가 분석되었다. 결과 본 연구 결과, 전반적인 신체활동 지지 수준은 4점 만점 $2.69{\pm}0.35$점이었고, 세부적으로 볼 때, 장비 또는 경제적 지원 $2.61{\pm}0.61$점, 모델링 $2.42{\pm}0.54$점, 지역사회자원 이용 $2.55{\pm}0.47$점, 좌식활동제한은 $3.18{\pm}0.51$점으로 나타나 신체활동 지지 수준은 중등도인 것으로 나타났으며, 이는 미국 부모의 지지와 비교하여 낮은 수준이다. 어머니의 아동 신체활동 지지에 대한 영향요인은 가정의 경제적 수준, 특히 월수입 500만 원 이상인 경우(${\beta}$=.417, p =.002)이며, 아동 신체활동 지지에 대한 어머니의 자기효능감(${\beta}$=.231, p =.003), 아동 신체활동 지지를 위한 충분한 정보(${\beta}$=.173, p =.022), 아동 신체활동 지지를 위한 교육경험(${\beta}$=.237, p =.002)이었다. 결론 본 연구의 결과에 의하면, 부모의 아동 신체활동 지지를 증진시키기 위해서는 부모의 신체활동 지지 자기효능감 증진을 위한 전략 개발과 충분한 전문적 정보제공이 필요하다. 추후연구로서 아동 신체활동 지지를 위한 부모교육 프로그램과 가족 중심의 아동 신체활동 증진 프로그램의 개발이 필요하며, 부모의 아동 신체활동 지지에 영향을 미치는 요인이 추가 탐색되어야 할 것이다.

• 한국임상약학회지
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• 제22권4호
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• pp.356-366
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• 2012

Background: Chemotherapy-induced peripheral neuropathy (CIPN) involving sensory and motor nerve damage or dysfunction is a common and serious clinical problem that affects many patients receiving cancer treatment. This condition may pose challenges for the clinician to diagnose and manage, particularly in patients with coexisting conditions or disorders that involve the peripheral nervous system. Many chemotherapeutic agents used today are associated with the development of serious and dose-limiting CIPN that can adversely affect the administration of planned therapy and can impair quality of life by interference with the patients' activities of daily living. The most important clinical objective in the evaluation of patients with CIPN is to determine their level of functional impairment involving activities of daily living. These findings are used to make medical decisions to continue, modify, delay, or stop treatment. The most commonly reported drugs to cause CIPN include taxanes, platinum agents, vinca alkaloids, thalidomide, and bortezomib. We aimed to determine PN incidence during cisplatin, carboplatin and oxaliplatin administration. Methods: We collected data from 125 patients who received at least one cycle of cisplatin, carboplatin or oxaliplatin. They completed a self-reported questionnaire and items related to their disease and peripheral neuropathy. The investigators filled in part of items about disease and treatment. Patient Neurotoxicity Qeustionnaire developed by Bionumerik company were applied for PN assessment. Results: The incidences of sensory neurotoxicities of cisplatin, carboplatin and oxaliplatin were respectively 23%, 56% and 50%. The incidences of motor neurotoxicities of cisplatin, carboplatin and oxaliplatin were respectively 18%, 42% and 19%. The incidences of severe neurotoxicities of cisplatin, carboplatin and oxaliplatin were respectively 13%, 28% and 14%. The incidences of PN were associated with cumulative dose but not age, gender and concurrent illness. 19.2% of the patients (24/125) were prescribed with gabapentin, nortriptyline or gabapentin plus nortriptyline to reduce these peripheral symptoms and 75% of the patients answered the drug were effective. Conclusion: Incidence of PN after cisplatin or oxaliplatin administration is cumulative dose-related. Physician-based assessments under-reported the incidence and severity of CIPN. To overcome this limitation, diagnostic tools specifically designed to assess peripheral neuropathy severity associated with chemotherapy must be developed.

• 대한소아치과학회지
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• 제29권3호
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• pp.318-327
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• 2002

뇌성마비인의 구강위생상태에 관한 조사를 위하여 $3{\sim}48$세의 뇌성마비인 총264명(남153명, 여111명)과 비교군으로 비슷한 연령대의 비뇌성마비인 220명(남125명, 여95명)을 대상으로 구강검사를 시행하고, 우식경험유치율(dft rate), 우식경험유치지수(dft index), 우식경험영구치율(DMFT rate), 우식경험영구치지수(DMFT index), 치태지수(plaque index)를 산출하여 비뇌성마비인과 비교하였으며, 지적, 행동, 언어장애의 정도, 유형 및 이환 부위, 거주형태, 보호자의 직업에 따라 분류, 비교하여 다음과 같은 결과를 얻었다. 1. DMFT rate, DMFT index, dft index에서 뇌성마비군과 비뇌성마비군의 유의한 차이가 없었고, dft rate는 유의한 차이로 뇌성마비군이 높게 나타났다. 2. 뇌성마비군의 성별, 유형 및 이환 부위별 비교에서 우식경험도의 유의한 차이를 보이지 않았다. 3. DMFT rate와 DMFT index는 각각의 장애의 정도가 심할수록 유의성 있는 차이로 감소하였으며, 거주형태에서는 수용군이 비수용군에 비해 낮았고, 보호자 직업에서는 자영업이 낮게 나타났다. 4. 치태지수에서 뇌성마비군이 비뇌성마비군보다 유의성 있게 높았고, 거주형태에서는 비수용군이, 보호자 직업에서는 스스로 벌어서 생활하는 경우가 유의성 있는 차이를 보이며 높게 나타났다. 5. 치태지수에서 뇌성마비군의 성별, 유형 및 이환 부위, 각각의 장애의 정도에 대해서는 유의한 차이를 보이고 있지 않았다.

• 한국학교ㆍ지역보건교육학회지
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• 제4권
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• pp.79-95
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• 2003

This dissertation aims to analyze various safety accidents taking place during physical education class according to physical education teacher's value orientation, to identify teacher's value orientation that can minimize safety accidents, and to provide basic materials for safe and smooth class management. For this purpose, data have been collected from 261 physical education teachers at some middle and high schools in G City in Kyung-Ki Province and Busan Metropolitan City. The materials were treated as follows: The variables on demographic characteristics of physical education teachers are determined by t-test ; The analysis of one-way ANOVA and relationship between value orientation and safety accident prevention activities was conducted through Pearson's linear correlation analysis and multiple regression; The analysis of the relationship between value orientation and actual conditions of safety accidents was conducted through logistic regression. First, there is almost no awareness difference of physical education teachers' value orientation according to demographical variables. The value orientation physical education teachers consider to be the most important is, however, mainly 'mastery of disciplinary lesson.' There is a statistically significant difference in safety accident prevention activities according to demographical variables. Teachers' focuses in class contents showed a significant difference according to teaching experience and working area, while the dependency on facility has a significant difference according to teaching experience and school type. Second, there is no correlation between physical education teacher's value orientation and safety accident prevention activities because there is virtually no statistically significant difference between them. It means that safety accident prevention activities are not related with on which teachers place emphasis among mastery of disciplinary lesson, social reconstruction, self-realization, ecological integration and value orientation on learning process. Third, the analysis of safety accident prevention activities according to physical education teachers' value orientation revealed that the lower value orientation in social reconstruction is, the more safety accidents teachers experience. It is also found that crashes among students, ball games and leg injuries are inter-related with social reconstruction in value orientation, over-motivation and unskilled motor function ; athletic sports with value orientation on learning process and safety prevention training ; unskilled motor functions with value orientation in ecological integration and disobedience to teacher's directions ; winter accidents with mastery of disciplinary lesson in value orientation. In conclusion, the research indicates that physical education teacher's value orientation according to demographical variables didn't show any significant difference, while one according to safety accident prevention activities showed significant difference. Besides, physical education teachers' value orientation is not related to safety accident prevention activities, but the relationship between value orientation and actual conditions of safety accidents showed correlations according to each variable. Especially, teachers with lower value orientation in social reconstruction experienced more safety accidents. Therefore, physical education teachers can manage physical education class more safely with more emphasis on value orientation in social reconstruction.

• Restorative Dentistry and Endodontics
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• 제33권2호
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• pp.141-147
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• 2008

본 연구의 목적은 나노리터 수준의 물 흐름을 계측할 수 있는 장치를 개발하고, 상아질의 물 투과성을 측정하여 치아과민증 치료제와 상아질 접착제의 상아세관 밀폐효과를 알아보고자 하였다. 본 연구에서 제작한 미세흐름 측정장치는 첫째, 물의 흐름을 감지하는 모세관과 광 센서부, 둘째 물의 흐름을 추적하는 서보모터와 구동부, 셋째, 모터의 회전을 측정하여 물의 이동량으로 변환하는 엔코더와 컴퓨터 기록장치 등 세 부분으로 구성되어 있다. 본 장비를 이용하여 교합 면이 절단되어 노출된 상아질의 물 투과도와 치아과민증 치료제인 BisBlock과 자가부식형 상아질접착제인 Clearfil SE bond의 상아질 밀폐효과를 측정하여 다음과 같은 결과를 얻었다. 1. 나노리터 수준의 물 흐름을 측정할 수 있는 장치를 제작하였고, 이를 이용하여 상아질의 물 투과도를 측정할 수 있었다. 2. 삭제 후 노출 연마된 상아질은 0.84 - 15.2 nL/s의 물 투과도를 보였고 Oxalate 제재인 BisBlock 이나 자가부식형 접착제 Cleafil SE bond 적용 시 투과도가 39.8 - 89.6% 감소하였다.

• 대한기계학회논문집A
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• 제41권7호
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• pp.655-663
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• 2017

ICT 기술의 발달로 로봇의 실내 활용이 증가하고 있다. 현재 이용되거나 향후 이용 범위가 증가할 수 있는 운반, 청소, 안내 로봇 등의 연구가 고도화 될 것이다. 실내 공간에서 이동 로봇 활용을 원활히 하기 위해 자기 위치 인식 문제는 가장 먼저 해결되어야 하는 중요한 연구이다. 추가적으로 이동 로봇의 위치가 인위적으로 이동되거나 예기치 못한 충돌로 인해 기존의 경로에서 이탈하였을 경우 등에서도 이동 로봇이 이런 상황을 인지하고 판단하여 목적지로 정확히 이동할 수 있는 강인한 시스템이 필요하다. 따라서 본 연구에서는 이동 로봇의 자기 위치 관련 여러 문제들을 해결하고자 실내에 설치되어 있는 다수의 CCTV 등 외부 영상 및 이를 절대 공간 좌표 변환한 정보와 더불어 이동 로봇의 엔코더 정보 등을 융합하여 강인한 위치 인식 시스템을 구현하였다. 추가로 이동 로봇 시스템에 경로 주행 알고리즘인 벡터 필드 히스토그램 기법을 적용하였고 실제 실험 수행 후 연구 결과를 확인하였다.

• 대한감각통합치료학회지
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• 제18권2호
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• pp.55-68
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• 2020

목적 : 본 연구에서는 최근 10년간 국내에서 발표된 아동 감각통합치료에 대한 중재효과를 체계적으로 분석하여 이해하기 쉽도록 제시하고자 한다. 연구방법 : 학술연구정보서비스(RISS)와 디비피아(DBpia)의 검색엔진을 사용하여 2011년에서 2020년 6월까지 출판된 국내 논문을 대상으로 하였다. 검색어는 "감각통합", "감각처리", "ASI(Ayres Sensory Integration)"이었다. 총 19개의 논문을 분석하였다. 연구결과는 PICO(Population, Interventions, Outcomes, Comparisons), 국제기능장애 건강분류(International Classification of Function, Disability and Health; ICF)방법과 수정한 The Evidence Alert Traffic Light Grading System을 사용하여 그림으로 제시하였다. 결과 : 아동 감각통합치료를 가장 많이 적용한 진단은 발달지연이었고, 중재법은 개별 감각통합치료가 가장 많았다. ICF의 신체구조 및 기능에 해당하는 중재는 91%에서 긍정적인 효과를 보였다, 세부 영역은 감각조절 및 감각처리, 소운동과 대운동, 신체도식, 신체-자기개념, 균형, 기본 움직임, 자세조절 및 손기능, 집중, 자존감이었다. 결론 : 아동 감각통합치료의 중재효과를 ICF의 분류와 그림으로 간단히 제시하여 치료사, 연구자, 아동의 가족들이 쉽게 이해하고 이용할 수 있는 근거를 마련하고자 하였다.

• 고신대학교 의과대학 학술지
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• 제33권2호
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• pp.181-190
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• 2018

Objectives: Our school introduced a new curriculum based on faculty-directed, intensive, small-group teaching of clinical skills in the third-year medical students. To examine its effects, we compared the mean scores on an OSCE between the third- and fourth-year medical students. Methods: Third- and fourth-year students did rotations at the same five OSCE stations. They then completed a brief self-reporting questionnaire survey to examine the degree of satisfaction with new curriculum in the third-year students and clinical practice in the fourth-year students, as well as their perception of confidence and preparedness. We analyzed the OSCE data obtained from 158 students, 133 of whom also completed the questionnaire. Results: Mean OSCE scores on the breast examination and wet smear stations were significantly higher in the third-year group (P < 0.001). But mean OSCE scores of motor-sensory examination and lumbar puncture were significantly higher in the fourth-year group (P < 0.05). The mean OSCE scores had no significant correlation with satisfaction. In addition, the self-ratings of confidence had a high degree of correlation with satisfaction with new curriculum (r = 0.673) and clinical practice (r = 0.692). Furthermore, there was a moderate degree of correlation between satisfaction and preparedness in both groups (r = 0.403 and 0.449). Conclusions: There is no significant difference in the effect on the degree of clinical performance and confidence between an intensive-small group teaching and a 1-year clinical practice. If combined, intensive small group teaching and clinical practice would be useful to improve the degree of ability and confidence in medical students.

• International Journal of Oral Biology
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• 제34권4호
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• pp.177-183
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• 2009

Human mesenchymal stem cell (hMSCs) isolated from human adult bone marrow have self-renewal capacity and can differentiate into multiple cell types in vitro and in vivo. A number of studies have now demonstrated that MSCs can differentiate into various neuronal populations. Due to their autologous characteristics, replacement therapy using MSCs is considered to be safe and does not involve immunological complications. The basic helix-loop-helix (bHLH) transcription factor Olig2 is necessary for the specification of both oligodendrocytes and motor neurons during vertebrate embryogenesis. To develop an efficient method for inducing neuronal differentiation from MSCs, we attempted to optimize the culture conditions and combination with Olig2 gene overexpression. We observed neuron-like morphological changes in the hMSCs under these induction conditions and examined neuronal marker expression in these cells by RTPCR and immunocytochemistry. Our data demonstrate that the combination of Olig2 overexpression and neuron-specific conditioned medium facilitates the neuronal differentiation of hMSCs in vitro. These results will advance the development of an efficient stem cell-mediated cell therapy for human neurodegenerative diseases.

• 대한간호학회지
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• 제45권1호
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• pp.14-24
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• 2015

Purpose: The purpose of this study was to measure the level of expectations regarding aging (ERA) and identify relationship between ERA and physical activity of middle aged adults. Methods: Participants were middle aged adults who resided in the community in three cities in Korea. Data were collected using questionnaires that contained items on individual characteristic, International Physical Activity Questionnaires (IPAQ), and behavior-specific cognitive factors including ERA-12. Hierarchical multiple regression was conducted to examine whether ERA would predict physical activity by controlling other factors. Results: The mean age of the participants was $51.1{\pm}6.9$ years. The mean score for ERA (possible range=0 to 100) was $40.04{\pm}14.31$. More than half of the participants (62.6%) were not engaged in health promoting physical activity. Gender, employment status and exercise confidence were associated with level of physical activity (F=7.14, p<.001, $R^2=.36$). After controlling for individual factors and behavior-specific cognitive factors, ERA was independently related to physical activity (F=7.19, p<.001, $R^2=.38$). Conclusion: The results demonstrate that individuals' belief about aging has effects on physical activity in Korean middle aged adults. Thus, nursing interventions which focused on ERA could help enhance physical activity in middle aged adults.