• 한국인터넷방송통신학회논문지
• /
• 제23권4호
• /
• pp.127-135
• /
• 2023

요즘, 우울증 및 스트레스로 자살하는 환자가 급증하고 있다. 뿐만 아니라, 스트레스 및 우울증이 오래 지속되면, 심장병 및 뇌 질환, 고혈압 등을 유발할 수 있는 위험한 요소로 질환이다. 그러나, 아무리 현대 의학이 발전하였지만, 우울증 및 심장병 환자에게는 특별한 약이나 치료제가 없는 매우 난감한 상황이다. 그러므로, 세계 여러 나라에서, 심전도 및 산소포화도, 뇌파 분석 기능을 이용해서 우울증 위험환자 및 자살 위험환자를 조기에 판단하는 연구가 활발하게 이루어지고 있다. 본 논문에서는, 이러한 문제점을 분석하기 위해서, 심장병 가설데이터를 수립해서, 심장병 위험환자를 판단하는 컴퓨터 모의실험을 수행하였다. 특히, 심장병 발생 예측을 을 10% 이상 향상하게 시키기 위해서, 퍼지 추론을 사용하는 모의실험을 수행하였다.

• 대한치위생과학회지
• /
• 제5권2호
• /
• pp.73-83
• /
• 2022

Background: This study was aimed at reducing depression and improving the quality of life and oral health of the elderly Koreans by elucidating the effect of depression on their life quality and oral health. Methods: Original data from the 8th National Health and Nutrition Survey (2019) were analyzed and implemented. The elderly (age≥65years) Koreans were enrolled. The oral health status was determined using the Decayed, Missing, Filled Teeth (DMFT) index and subjective self-report. The quality of life was quantified as the sum of score of each item in the Euro Qol-5 dimension (EQ-5D) and Health-related Quality of Life Instrument with 8 Items (HINT-8). The t-test, one-way analysis of variance, correlation analysis, and multiple regression analysis were performed to statistically compare the quality of life, oral health status, and oral health status according to the depression status. Results: EQ-5D and HINT-8 scores differed significantly with the history of depression, current depression, stress perception, depression for 2 weeks, and annual suicidal intention (p≤0.05). The DMFT index score differed significantly with the depression diagnosis and depression for 2 weeks (p≤0.05). EQ-5D, HINT-8, and DMFT index differed significantly with all oral health behavior variables (p≤ 0.05). Conclusions: The results of this study could serve as a basis to formulate oral health programs for the elderly to reduce depression and improve the quality of life.

• 지역사회간호학회지
• /
• 제33권1호
• /
• pp.128-138
• /
• 2022

Purpose: This study aimed to identify the factors influencing the wellness of call center employees. Methods: From December 2018 to October 2019, a cross-sectional study was conducted with 155 workers recruited from the call centers in Seoul, South Korea. Data were collected using self-administered questionnaires. The questionnaires were used to measure the following scales: Korean occupational stress scale, emotional labor scale, work-life balance scale and wellness scale. Using the SPSS 26.0 program, the descriptive statistics, independent t-test, ANOVA, correlation analysis, and multiple regression analysis were conducted. Results: The mean score of the wellness level of call center employees was 3.05 out of a maximum of 5.00. More wellness level of call center employees was associated with gender, psychiatric diagnosis, and call characteristics. A multiple regression analysis indicated that the total scores on the wellness scale were predicted by call characteristics, occupational stress and work-life balance, with an explanatory power of 42.2%. Conclusion: Study findings show that it is necessary to promote wellness in call center workers with differentiated strategies according to call characteristics, occupational stress and work-life balance. This implies that it is necessary to understand the call characteristics and patterns of workers and to provide an innovative wellness program tailored to individual characteristics for an effective management of the emotional labor and occupational stress.

• 한국체육학회지인문사회과학편
• /
• 제55권2호
• /
• pp.11-22
• /
• 2016

루만의 체계이론에 입각해서 기존의 반-도핑 커뮤니케이션을 분석한 결과 다음과 같은 결론에 도달하였다. 기존의 반-도핑 커뮤니케이션은 도핑의 원인과 책임을 개인에게 귀속시키는 개인화 전략을 구사하고 있다. 따라서 문제 해결 방법도 적발, 처벌, 교육을 통한 계몽 같이 철저하게 선수나 지도자 같은 개인에게 초점을 맞추고 있다. 이와 같은 전략은 스포츠체계와 그 주변 체계들의 이해관계가 거미줄처럼 복잡하게 얽혀져 생겨나는 도핑현상을 개인의 자유의지에 따른 결정의 결과로 단순화시킬 뿐만 아니라, 스포츠 및 주변체계들의 성찰 기회를 차단함으로써 체계 내부의 구조적 문제를 은폐시키는데 기여하고, 선수나 트레이너 같은 개별 행위자에게 받아들여지기 어려운 무리한 요구를 부과함으로써 도핑방지노력이 실효를 거둘 수 없게 만든다. 도핑 퇴치 노력이 효력을 발휘하기 위해서는 주체 중심 차원을 넘어서 스포츠조직과 사회적 기능체계들의 차원에서 전략을 구상하고 실행해야 한다.

• 한국방사선학회논문지
• /
• 제17권3호
• /
• pp.459-464
• /
• 2023

첨단 기술의 발전으로 디지털 방사선영상 장비들이 많이 개발되어 정확한 진단과 치료에 많은 도움을 받고 있으며, 이를 안전하고 효과적으로 사용하기 위하여 전문적인 지식을 습득한 인력양성이 매우 중요하다. 진단용 X선 장비를 활용한 촬영 실습 교육에 있어서 학생들은 방사선 피폭의 위험성에 노출되어 있고, 일부 교육기관에서는 원자력안전법에 따른 관리의 어려움으로 X선 장비를 사용하지 않는 경우도 발생하고 있다. 이에 대한 해결책으로, 본 연구에서는 비전 센서와 자체 개발한 소프트웨어를 활용하여 방사선이 발생하지 않는 교육용 의료방사선 시뮬레이터를 개발하였고, 이를 통해 교육기관은 법에 따른 행정 이행 사항의 부담을 줄일 수 있고, 학생들은 방사선 피폭이 없는 건강한 실습환경에서 높은 수준의 교육 효과를 얻을 수 있게 하였다.

• Tuberculosis and Respiratory Diseases
• /
• 제86권3호
• /
• pp.216-225
• /
• 2023

Background: Tuberculosis (TB)-related stigma has been well-documented. Since the emergence of the coronavirus disease 2019 (COVID-19), different organizations have been alerted to the fact that stigma could arise again. Due to stigma's negative effects, this qualitative study aimed to explore the stigma felt by patients by evaluating the following: COVID-19 stigma and its temporal progression through the pandemic; stigma perceived by different patients with TB before and during COVID-19 pandemic; and difference perceived by individuals who contracted both diseases. Methods: A semi-structured interview was developed according to the available literature on the theme. It was performed individually in 2022 upon receiving signed informed consent. Participants were recruited with a purposive sampling approach by searching medical records. Those who currently or previously had pulmonary TB and/or COVID-19 were included. Data were subjected to thematic analysis. Results: Nine patients were interviewed, including six (66.7%) females. The median age of patients was 51±14.7 years. Four participants (44.4%) had completed high school and four (44.4%) were never smokers. Three had both TB and COVID-19. Four only had TB and two only had COVID-19. Interviews identified eight main themes: knowledge and beliefs, with several misconceptions identified; attitudes towards the disease, varying from social support to exclusion; knowledge and education, assumed as of extreme importance; internalized stigma, with self-rejection; experienced stigma, with discrimination episodes; anticipated stigma, modifying actions for avoiding stigma; perceived stigma, with judgment by others prevailed; and temporal evolution of stigma. Conclusion: Individuals expressed strong stigma for both diseases. De-stigmatization of respiratory infectious diseases is crucial for limiting stigma's negative impact.

• Journal of Digestive Cancer Research
• /
• 제4권1호
• /
• pp.1-9
• /
• 2016

The abundance of multi-drug resistance ATPase binding cassette and deranged self-renewal pathways shown in cancer stem cells (CSCs) played a crucial role in tumorigenesis, tumor resistance, tumor recurrence, and tumor metastasis. Therefore, elucidation of CSCs biology can improve diagnosis, enable targeted treatment, and guide the follow up of GI cancer patients. In order to achieve chemoquiescence, seizing cancer through complete ablation of CSCs, CSCs are rational targets for the design of interventions that will enhance responsiveness to traditional therapeutic strategies and contribute in the prevention of local recurrence as well as metastasis. However, current cancer treatment strategies fail to either detect or differentiate the CSCs from their non-tumorigenic progenies mostly due to the absence of specific biomarkers and potent agents to kill CSCs. Recent advances in knowledge of CSCs enable to produce several candidates to ablate CSCs in gastrointestinal (GI) cancers, especially cancers originated from inflammation-driven mutagenesis such as Barrett's esophagus (BE), Helicobacter pylori-associated gastric cancer, and colitis-associated cancer (CAC). Our research teams elucidated through revisiting old drugs that proton pump inhibitor (PPI) and potassium competitive acid blocker (p-CAB) beyond authentic acid suppression, chloroquine for autophage inhibition, sonic hedgehog (SHH) inhibitors, and Wnt/β-catenin/NOTCH inhibitor can ablate CSCs specifically and efficiently. Furthermore, nanoformulations of these molecules could provide an additional advantage for more selective targeting of the pathways existing in CSCs just like current molecular targeted therapeutics and sustained action, while normal stem cells intact. In this review article, the novel approach specifically to ablate CSCs existing in GI cancers will be introduced with the introduction of explored mode of action.

• 대한불안의학회지
• /
• 제19권2호
• /
• pp.69-76
• /
• 2023

Objective : This study aimed to find out whether the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) scales are useful in distinguishing social anxiety disorder, panic disorder, and major depressive disorder. Methods : The study sample included 118 patients: 33 with social anxiety disorder, 53 with major depressive disorder, and 32 with panic disorder. Participants were classified according to the diagnosis indicated on their medical records. MMPI-2-RF scores were derived from MMPI-2 protocols. Results : The results of multivariate analysis of variance showed that the elevated scales were consistent with the diagnostic and clinical characteristics of each diafnostic group. Logistic regression analyses identified several scales that were useful in differentiating the diagnostic groups. The higher Cognitive Complaints (COG) scale significantly differentiated major depressive disorder from the other groups. The higher Self-Doubt (SFD) scale and Somatic Complaints (RC1) scale were useful in differentiating social anxiety disorder and panic disorder respectively. The lower Cynicism (RC3) scale was also useful in differentiating social anxiety disorder. Other scales that were useful in distinguishing between pairs of groups were also identified. Conclusion : The results of this study suggest that the MMPI-2-RF scales can be useful for discriminating anxiety disorders.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제34권4호
• /
• pp.268-274
• /
• 2023

Objectives: This study investigated whether the Minnesota Multiphasic Personality Inventory-Adolescent Restructured Form (MMPI-ARF) can differentiate between two groups of adolescents, one diagnosed with internalizing disorders and another with externalizing disorders, and examined the clinical utility of the MMPI-A-RF by examining which subscales can significantly discriminate between these two groups. Methods: A total of 105 adolescents aged 13-18 years completed the MMPI-A-RF (53 internalizing disorder and 52 externalizing disorder groups). Independent t-test, chi-square test (χ²), and discriminant analysis were used to examine whether MMPI-A-RF can distinguish between the two groups. Results: Sixteen MMPI-A-RF scales best predicted differences between the groups with internalizing and externalizing disorders. Fourteen scales (Higher-Order Scale [Emotional/Internalizing Dysfunction], Restructured Clinical [RC] Scale [RC demoralization, Somatic Complaints (RC1), and Low Positive Emotions (RC2)], Personality Psychopathology Five Scale [Introversion/Low Positive Emotionality-Revised, Negative Emotionality/Neuroticism-Revised], Somatic/Cognitive Scale [Malaise, Head Pain Complaints, and Gastrointestinal Complaints], Internalizing Scale [Stress/Worry, Self-Doubt], Externalizing Scale [Negative School Attitudes], Interpersonal Scale [Social Avoidance, Shyness]) were associated with the internalizing disorder group, whereas two scales (Externalizing Scale [Conduct Problems, Negative Peer Influence]) were associated with the externalizing disorder group. Conclusion: The MMPI-A-RF can be an efficient assessment tool for a quick diagnosis as it can classify individuals with internalizing and externalizing disorders in clinical settings that lack a variety of assessment tools for children and adolescents.

• 사상체질의학회지
• /
• 제35권4호
• /
• pp.42-54
• /
• 2023

Objectives This study aims to identify differences in clinical manifestations of COVID-19 between different Sasang constitution. Methods Subjects were recruited from August 29, 2022, to July 11, 2023. COVID-19 clinical symptoms were self-reported via questionnaires. Sasang constitutional diagnosis was performed using the K-PRISM, and Sasang constitutional specialist. Results A total of 66 subjects were recruited for the study, and the Sasang constitutional distribution of the subjects was 19 soyangin, 25 taeeumin, and 22 soeumin. For most of the COVID-19 clinical manifestations, the study found that soyangin experienced symptoms at a higher rate than other constitutions. Among the symptoms observed in the study, sore throat, pantalgia, and cough were severe in all subjects regardless of constitution. Soeumin was more likely to experience abdominal pain, chest pain, and diarrhea, while soyangin was more likely to experience chest pain, nausea/vomiting, diarrhea, and cutaneous symptoms compared to other constitutions. Taeeumin had more sputm, nasal congestion, and skin symptoms, but fewer digestive symptoms. There were differences in the onset and duration of symptoms by constitution. Conclusions This study is an important contribution to our understanding of the differences in response to the COVID-19 virus among different Sasang constitutions. Symptomatic differences between constitutions may have important implications for prevention and treatment strategies for infectious diseases, and personalized treatment and management based on these differences may be needed in the future.