• Title/Summary/Keyword: Selenium-75

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A Study on Pancreas Scanning with $Selenium^{75}$-Selenomethionine ($^{75}Se$-Selenomethionine 을 이용(利用)한 췌장주사(膵臟走査)에 관(關)한 연구(硏究))

  • Shin, Hyun-Chan;Toh, Sang-Hee;Ra, Woo-Youn;Suh, Chul-Sung
    • The Korean Journal of Nuclear Medicine
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    • v.2 no.1
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    • pp.21-25
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    • 1968
  • Radiographic visualization of the pancreas is a difficult problem, but the direct visualization of the pancreas is possible by the injection of the amino-acid methionine tagged with $selenium^{75}$75 ($Se^{75}$). In order to know the diagnostic value of pancreas scanning, scans were performed on 23 cases using $selenium^{75}$-selenomethionine. These cases were also given egg white, probanthine and morphine. 1. Good visualization of the pancreas scanning was observed on 19 cases, presumably with normal pancreas. 2. A case which showed diffusely decreased uptake on pancreas scanning was proven to have lesions in the bile duct and the gall bladder. 3. Of those two cases which showed localized cold area, one had pancreas cyst and the other one was not explored. 4. A case which showed no visualization of the pancreas was proven to have pancreatic carcinoma. 5. Two cases which showed widened duodenal loop by upper gastro-intestinal series revealed normal pancreas scanning, and no pancreatic disease was found in both cases.

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Antioxidant Activities of Selenium-Treated Spinacia oleracea L. (셀레늄 강화 시금치의 항산화 활성)

  • Song, Won-Yeong;Chun, Sung-Sik;Choi, Jeong-Hwa
    • Journal of Food Hygiene and Safety
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    • v.33 no.6
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    • pp.510-515
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    • 2018
  • In the present study, we investigated the anti-oxidant activities of selenium-treated Spinacia oleracea L. by utilizing experiments in vitro assays. The selenium content of non-treated spinach in this study was noted at $61.19{\mu}g/kg$, whereby the selenium-treated spinach which was treated by a 2000 mg/kg selenium was 1000-fold diluted, and was reported to be about 4 times higher than that of non-treated spinach. In this case, the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity in the concentration of selenium-treated spinach, 0.1~1.0 mg/mL was measured as stronger than that of the identified non-treated spinach. By the same token, the DPPH radical activity of non-treated spinach and selenium-treated spinach was recorded as 46.05~52.75% and 49.52~59.09% respectively. It is emphasized that the 2,2'-azino-di-2-ethyl-benzthiazoline-sulphonate (ABTS) radical scavenging activity as revealed in the concentration of selenium-treated spinach, 0.1~1.0 mg/mL was noted as being stronger than that of non-treated spinach. The ABTS radical activity of non-treated spinach and selenium-treated spinach was 11.85~52.01% and 27.14~53.59% respectively. In this respect, the nitric oxide (NO) radical scavenging activity and reducing power activity in the concentration of selenium-treated spinach, 0.1~1.0 mg/mL was identified and noted as stronger than that of non-treated spinach. These results suggest that selenium-treated spinach could possibly be more useful as a potential antioxidant to improve human health outcomes, than the non-treated spinach.

Effect of a Copper, Selenium and Cobalt Soluble Glass Bolus Given to Grazing Yaks

  • Liu, Zongping
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.9
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    • pp.1433-1437
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    • 2007
  • Two field trials were carried out to evaluate the performance of a soluble glass copper, cobalt and selenium bolus for maintaining adequate levels of the three trace elements in yaks. Forty yaks were used in trial 1 and 60 yaks were used in trial 2. In each trial two commercial soluble glass boluses were administered to half of the yaks. Blood samples were taken from the jugular vein at day 0, 30, 60, 90 in trial 1 and at day 0, 45, 75 and 105 in trial 2. The samples were analysed for copper status (serum caeruloplasmin activity and copper concentration), cobalt status (serum vitamin $B_{12}$ concentration and cobalt concentration), selenium status (erythrocyte glutathione peroxidase activity and selenium concentration) and serum zinc concentration. The erythrocyte glutathione peroxidase activities, serum caeruloplasmin activities and serum vitamin $B_{12}$ concentrations for trial 1 and 2 were all significantly increased for the bolused yaks (p<0.001 or p<0.01) on all sampling days. The bolused yaks had a significantly higher selenium and copper status in serum than the control yaks on all sampling days in trial 1 and 2 (p<0.05 or p<0.01). There were no significant differences in zinc and cobalt concentrations between the bolused yaks and the controls.

Increasing sperm production and improving cryosurvival of semen in aged Thai native roosters as affected by selenium supplementation

  • Supakorn Authaida;Ruthaiporn Ratchamak;Wuttigrai Boonkum;Vibuntita Chankitisakul
    • Animal Bioscience
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    • v.36 no.11
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    • pp.1647-1654
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    • 2023
  • Objective: Aging roosters typically exhibit subfertility with decreasing semen quality, furthermore Thai native roosters reared in rural areas are raised for a longer duration than their usual lifespan. The present study therefore aimed to assess the effect of selenium supplementation as an antioxidative substance in diets to improve the semen cryopreservation of aged roosters. Methods: Semen samples were collected from young (n = 20) and aged (n = 20) Thai native roosters (Pradu Hang Dum) at 36 and 105 weeks of age when starting the experiment, respectively. They were fed diets either non-supplemented or supplemented with selenium (0.75 ppm). Fresh semen quality and lipid peroxidation of fresh semen was evaluated before cryopreservation using the traditional liquid nitrogen vapor method. Post-thaw sperm quality and fertility potential were determined. Results: Advancing age is unrelated to decreasing fresh semen quality (p>0.05). However, lipid peroxidation in rooster semen depended on age, and the malondialdehyde (MDA) concentration increased in aged roosters (p<0.05). Selenium supplementation in diets significantly decreased the MDA concentration and increased the sperm concentration (p<0.05). In contrast, cryopreserved semen was affected by advancing rooster age, and selenium influenced sperm quality (p<0.05). Younger roosters had higher post-thaw sperm quality and fertility potential than aged roosters (p<0.05). Likewise, diet selenium supplements improved post-thaw sperm quality and fertility compared with the non-supplement group. Conclusion: Rooster's age does not influence the rooster sperm quality of fresh semen, while sperm cryotolerance and fertility were greater in young roosters than in aged roosters. However, sperm of aged roosters could be improved by dietary selenium supplementation.

Effect of Selenium Added High fat Diets on the Serum Lipid Components in Rats (Selenium첨가 고지방식이가 흰쥐의 혈청지질 성분에 미치는 영향)

  • Cho, Eun-Hee;Cho, Jung-Sun
    • Journal of the Korean Applied Science and Technology
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    • v.6 no.1
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    • pp.75-85
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    • 1989
  • This paper in the feeding Selenium added high fat diet, have an aim to find an effect of the white rat'food intake, body weight and level of serum lipid. This experimentations com to the conclusion that Se. added high fat diets, to say again, soybean oil added high fat diets that expecially is contained unsaturated high fatty acid, improve a general diet-utility factor, and decrease a body weight and coronary heart desease factor of the serum have an effect to prevent them from C H D by increasing anti - arterioscleroticfactor.

Selenium Status of Healthy Women Consuming Different Diets (식이에 따른 건강한 성인 여자의 셀레늄의 영양 상태)

  • Huh Chai Ok
    • Journal of Nutrition and Health
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    • v.26 no.7
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    • pp.899-906
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    • 1993
  • Human blood selenicum(Se) level depends on the Se content and bioavailablilty of foods. In countries where the soil has low Se content, the differences of Se intake and blood Se concentration are shown according to the type of diet. In this study, Se status of women eating an average German diet(175 German healthy women) and wholesome nutrition group(243 women) were studied. There were significant differences in wholeblood and plasma Se levels between the two groups. In average German diet group, mean wholeblood Se concentration was 84.97ug/l and plasma Se concentration was 75.02ug/l. In wholesome nutrition group mean wholeblood Se concentration and plasma Se concentration with Se levels, correlation analysis was conducted between Se concentration and BMI, age and daily food intake. BMI and age did not correlate significantly with wholeblood and plasma Se levels. In wholesome nutrition group, serum and wholeblood Se levels had significant correlation with fish intake.

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The Effects of Endurance Exercise and Selenium Treatment on Mitochondrial Transcription Factors Expression in Old GK Rats (지구성 운동과 셀레늄 투여가 노화 GK 흰쥐의 미토콘드리아 전사인자 발현에 미치는 영향)

  • Kim, Bum-Soo
    • Development and Reproduction
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    • v.14 no.2
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    • pp.75-82
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    • 2010
  • The objective of this study is to identify the effects of endurance exercise and selenium on mitochondrial transcription factor in old Goto-Kakizaki (GK) rats. In this experiments, endurance exercise were treadmill-run at 24 m/min, 30 min/day, 5 days/week, 6 weeks and 5 umol/kg of sodium selenite was injected intraperitoneally. In exercise group, selenium group, and combination group, the mitohondrial biogenesis-related genes, including PGC-$1{\alpha}$, NRF-1, and Tfam expression level were significantly increased compared to control group. Consistent with the increased biogenesis-related genes, the cytochrome C in the treated groups, which was the indicator of mitochondrial content, was significantly increased compared to control group. Especially, combination of exercise and selenium may be effective in the increase of mitochondrial biogenesis, activity and insulin sensitivity. Therefore, exercise and selenium treatment is likely to promote diabeticmitochondrial malfunction and then improve diabetes.

Effects of L-carnitine, Selenium-enriched Yeast, Jujube Fruit and Hwangto (Red Clay) Supplementation on Performance and Carcass Measurements of Finishing Pigs

  • Han, Yung-Keun;Thacker, P.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.2
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    • pp.217-223
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    • 2006
  • Fifty castrated crossbred ($Landrace{\times}Yorkshire$) pigs, weighing an average of $60.6{\pm}3.1kg$ were allotted to one of five treatments in a randomized block design to examine the effects of dietary inclusion of 0.1% L-carnitine (50 ppm carnitine), 0.1% selenium-enriched yeast (0.3 ppm selenium), 0.1% Jujube fruit or 0.1% Hwangto (Red clay) on pig performance and carcass quality. All diets were based on corn, wheat, soybean meal and wheat bran and were formulated to supply 13.8 MJ DE/kg. Dietary supplementation did not influence daily gain (p = 0.57), feed intake (p = 0.52), or feed conversion (p = 0.32). Digestibility of dry matter (p = 0.60), organic matter (p = 0.74), crude protein (p = 0.76), crude fibre (p = 0.70) and energy (p = 0.75) were also unaffected by inclusion of any of the additives. Tissue samples taken from the longissimus muscle showed that the levels of carnitine (p = 0.0001) and selenium (p = 0.0001) were significantly higher with dietary inclusion of carnitine or selenium-enriched yeast. Dietary treatment did not affect dressing percentage (p = 0.33), carcass lean yield (p = 0.99) or first, $10^{th}$ and last rib midline backfat depth (p = 0.45, 0.82 and 0.47, respectively). Dietary treatment also did not affect the percentages of tenderloin (p = 0.37), bacon (p = 0.36), fat and bone (p = 0.56), picnic shoulder (p = 0.25), skirt (p = 0.80), fresh ham (p = 0.31) or ribs (p = 0.79). However, pigs fed the diet containing Jujube fruit had a higher percentage of Boston butt than pigs fed the carnitine or selenium supplemented diets (p = 0.01). Pigs fed added Hwangto had a higher (p = 0.04) percentage of loin compared with pigs fed supplementary selenium or Jujube fruit. Loin muscle from pigs fed carnitine had a significantly lower Hunter colour value for L (whiteness, p = 0.004) and a higher value for $a^*$ (redness; p = 0.069). The overall results indicate that supplementation with L-carnitine and selenium-enriched yeast can produce pork containing higher levels of carnitine and selenium, which could provide health benefits for consumers of pork without detrimental effects on pig performance.

A Comparative Study on the Determination of the Selenium in Biological Samples using 75Se and 77mSe Nuclides (75Se과 77mSe 핵종을 이용한 생물시료 중의 셀렌 분석에 대한 비교 연구)

  • Moon, Jong-Hwa;Kang, Sang-Hoon;Kim, Sun-Ha;Chung, Yong-Sam;Kim, Young-Jin
    • Analytical Science and Technology
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    • v.18 no.1
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    • pp.23-26
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    • 2005
  • Se is well known as an anti-oxidant trace element and many customers are interested in an analysis and contents of Se in the various foodstuff samples. This study was aimed at establishig and comparing an analytical method for the determination of the Se in biological samples by neutron activation analysis using two nuclides, $^{75}Se$ and $^{77m}Se$. Keeping this objective, three NIST biological standard reference materials were chosen and the concentrations of the Se were determined under the prefixed analytical conditions such as the irradiation, decay and measurement time. The measured values by both analytical methods were evaluated with certified values. In addition, the detection limits and measurement uncertainty for the analytical results using $^{75}Se$ and $^{77m}Se$ were compared with each other.