• 대한조선학회논문집
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• 제34권4호
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• pp.72-83
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• 1997

본 연구에서는 연안 및 운하, 두 곳 모두에서 운항이 가능한 컨테이너선에 대한 선형설계를 수행하였다. 설계된 선형은 기존의 140TEU 컨테이너선을 기준선으로 하여 설계된 200TEU급 컨테이너 선형으로, 선수부에 대하여는 기존의 저항시험 자료들을 통한 선형의 재설계도 시도되었다. 모형시험은 선형시험수조에서 일반적인 저항시험을 통한 전저항, 침하와 트림(trim)이 제측되었으며, 선체주위 유동장의 해석을 위한 수치해석으로는 무한수심 뿐만 아니라 제한수로상태에 대하여도 MAC법을 기초로 한 유한차분법(Finite-Difference Method)에 의해 계산이 수행되었다. 이러한 일련의 모형시험 및 유동장의 수치해석을 통하여 설계된 선형의 저항 특성을 파악하였다.

• 한국구조물진단유지관리공학회 논문집
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• 제7권1호
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• pp.165-172
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• 2003

The fatigue problem of Prestressed Concrete(PSC) bridges are more serious than the other type of concrete bridges, because the cross sectional area and self weight of PSC bridges are smaller. The endurance of strengthening methods for PSC bridges are tested in this study. Glass fiber sheeting and external post-tensioning methods were applied. 1/5 scale PSC beams were made for fatigue test, same as static test. The range of repeated load is from 10% to 80% of yielding load with sine curve. The experimental results show that the failure cycle of strengthened members are increased compare to non-strengthened members. The members strengthened with glass fiber show better enhancement in fatigue problem than the members strengthened with external post-tensioning method, though the adhesion of glass fiber and concrete is failed, as increase of crack. With these experimental results, it can be said that the strengthening methods used in this study are efficient at extending the life time of aged PSC bridges.

• 유공압시스템학회논문집
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• 제3권4호
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• pp.14-20
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• 2006

Recently, the on-off solenoid valves have been focused on core technology in the fields of the production line of semi-conductor chips and the micro fluid chips for bio-medical applications. A key characteristics for on-off solenoid valve, operated by compressed air, are high speed response and great repeatability. Indeed, it is also important to keep the pressure on the cross-sectional area of the poppet to be constant regardless of the fluctuation of the pressure exerted on the ports. In this study, we have designed and analysed the high-speed and high flow rate on-off solenoid valve using the analogy of equivalent magnetic circuit and Finite Element Method (FEM) respectively. In case of poppet, flow field characteristics was analyzed by the variation of poppet and it was able to display flow field by changing the location of the poppet. Also, we verified possibility of the design through the static and dynamic pressure and the 3D simulation using distribution curve of the force by working the front poppet.

• 생태와환경
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• 제46권1호
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• pp.94-102
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• 2013

본 연구는 단면변화를 고려한 수위-단면적 변화 및 평균 유속-단면적 간의 상관관계를 분석하여 유량 산정 및 하천관리에 활용하고자 하였다. 수위에 따른 단면적 변화는 SB-A 지점은 1.0 m, 1.9 m, SB-C 지점은 0.6 m, 1.8 m, CL-A 지점은 1.0 m, 1.8 m, OS-A 지점은 0.6 m, 2.0m에서 발생되었다. 이 중 첫 번째 변화는 평 저수기에 해당되고, 두 번째 변화는 홍수기 및 하천 좌 우 안에 인위적 자연적으로 형성된 둔치 등으로 판단된다. 수위-단면적 변화에 따른 관계식의 기울기는 지수형 0.5539~1.9013, 선형 9.040~52.544의 범위를 가진다. 기울기는 두 곡선 모두 고수위로 갈수록 증가하는 경향을 보인다. 평균유속-단면적 변화의 관계는 지수와 직선의 방정식으로 지수형 기울기와 상관계수는 각각 0.1182~0.8734, 0.22~0.86이며, 선형의 기울기와 상관계수는 0.0028~0.1032, 0.20~0.87로 분석되었다. SB-A, SB-C 지점의 저수위는 다른 수위보다 상관관계가 높게 산정되었는데, 이는 수위구간이 좁고, 하천 단면적의 변화가 크지 않기 때문으로 판단된다. CL-A, OS-A 지점은 월류보의 영향으로 저수위일 경우에 상관관계가 낮았다. 수위-단면적, 평균유속-단면적의 상관관계 및 곡선식 등을 이용하여 하천 정비계획 등의 수립에 활용할 수 있으며, 제외지의 단면적이 변하는 지점의 유량 변화 등의 예측에 활용할 수 있을 것이다.

• Clinical and Experimental Pediatrics
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• 제58권8호
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• pp.294-300
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• 2015

Purpose: It is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development. Methods: This study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test. Results: A total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, $2.45{\pm}0.50cm$ vs. $2.63{\pm}0.49cm$, P=0.015; uterine volume, $0.95{\pm}0.62cm^3$ vs. $1.35{\pm}0.76cm^3$, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least $1.07cm^3$ was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747). Conclusion: Uterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls.

• Korean Journal of Radiology
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• 제23권2호
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• pp.237-245
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• 2022

Objective: Viscoelasticity is an essential feature of nerves, although little is known about their viscous properties. The discovery of shear wave dispersion (SWD) imaging has presented a new approach for the non-invasive evaluation of tissue viscosity. The present study investigated the feasibility of using SWD imaging to evaluate diabetic neuropathy using the sciatic nerve in a diabetic rat model. Materials and Methods: This study included 11 diabetic rats in the diabetic group and 12 healthy rats in the control group. Bilateral sciatic nerves were evaluated 3 months after treatment with streptozotocin. We measured the nerve cross-sectional area (CSA), nerve stiffness using shear wave elastography (SWE), and nerve viscosity using SWD imaging. The motor nerve conduction velocity (MNCV) was also measured. These four indicators and the histology of the sciatic nerves were then compared between the two groups. The performance of CSA, SWE, and SWD imaging in distinguishing the two groups was assessed using receiver operating characteristic (ROC) analysis. Results: Nerve CSA, stiffness, and viscosity in the diabetic group was significantly higher than those in the control group (all p < 0.05). The results also revealed a significantly lower MNCV in the diabetic group (p = 0.005). Additionally, the density of myelinated fibers was significantly lower in the diabetic group (p = 0.004). The average thickness of the myelin sheath was also lower in the diabetic group (p = 0.012). The area under the ROC curve for distinguishing the diabetic neuropathy group from the control group was 0.876 for SWD imaging, which was significantly greater than 0.677 for CSA (p = 0.030) and 0.705 for SWE (p = 0.035). Conclusion: Sciatic nerve viscosity measured using SWD imaging was significantly higher in diabetic rats. The viscosity measured using SWD imaging performed well in distinguishing the diabetic neuropathy group from the control group. Therefore, SWD imaging may be a promising method for the evaluation of diabetic neuropathy.

• Journal of the Korean Data and Information Science Society
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• 제28권6호
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• pp.1337-1348
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• 2017

본 연구는 질병관리본부에서 실시한 전국 규모의 자료인 지역사회건강조사 2014년 자료를 이용하여 고위험 음주자들의 특성 및 요인을 파악하고 고위험 음주 예측모형을 개발했다. 예측모형 개발은 데이터마이닝 방법 중 로지스틱 회귀분석, 의사결정나무, 신경망 분석 3가지 방법을 적용했으며, 로지스틱 회귀분석의 주요 결과로는 40대 남자의 위험도가 높았고, 사무직과 판매서비스직의 위험도가 높았다. 특히 현재 흡연자인 경우 고위험 음주 위험도가 높았다. 3가지 방법 중 AUROC (area under a receiver operation characteristic curve) 측면에서 신경망 분석과 로지스틱 회귀분석이 가장 높게 나타났다. 또한 고위험 음주 예방을 위한 우선 관리 대상자를 선정함에 있어 신경망 분석과 로지스틱 회귀분석으로 개발된 예측모형의 사후확률을 기초로 두 가지 모형 모두 예측분포의 상위 10%인 집단에 해당되는 경우를 선정한 결과 신경망 분석이나 로지스틱 회귀모형 1가지 모형으로 적용하는 것보다 반응률 및 향상도가 다소 개선되는 것으로 나타났다. 본 연구에서 개발된 고위험 음주 예측모형과 우선 관리 대상자 선정 방법은 문제적 음주 예방 및 개선 교육, 절주 프로그램 개발 등에 보다 세분화되고 효과적인 건강관리 서비스를 제공을 위한 기초자료가 될 수 있을 것이다.

• The Korean Journal of Pain
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• 제36권1호
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• pp.113-127
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• 2023

Background: Resting-state functional connectivity (rs-FC) may aid in understanding the link between painmodulating brain regions and the descending pain modulatory system (DPMS) in fibromyalgia (FM). This study investigated whether the differences in rs-FC of the primary somatosensory cortex in responders and non-responders to the conditioned pain modulation test (CPM-test) are related to pain, sleep quality, central sensitization, and the impact of FM on quality of life. Methods: This cross-sectional study included 33 females with FM. rs-FC was assessed by functional magnetic resonance imaging. Change in the numerical pain scale during the CPM-test assessed the DPMS function. Subjects were classified either as non-responders (i.e., DPMS dysfunction, n = 13) or responders (n = 20) to CPM-test. A generalized linear model (GLM) and a receiver operating characteristic (ROC) curve analysis were performed to check the accuracy of the rs-FC to differentiate each group. Results: Non-responders showed a decreased rs-FC between the left somatosensory cortex (S1) and the periaqueductal gray (PAG) (P < 0.001). The GLM analysis revealed that the S1-PAG rs-FC in the left-brain hemisphere was positively correlated with a central sensitization symptom and negatively correlated with sleep quality and pain scores. ROC curve analysis showed that left S1-PAG rs-FC offers a sensitivity and specificity of 85% or higher (area under the curve, 0.78, 95% confidence interval, 0.63-0.94) to discriminate who does/does not respond to the CPM-test. Conclusions: These results support using the rs-FC patterns in the left S1-PAG as a marker for predicting CPM-test response, which may aid in treatment individualization in FM patients.

• 한국산림과학회지
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• 제81권1호
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• pp.1-10
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• 1992

본(本) 연구(硏究)는 신갈나무 장령임분(壯齡林分)의 물질생산(物質生産) 구조(構造)의 특성(特性)을 밝히기 위한 일련의 연구(硏究)로 특히, 줄기의 변재단면적(邊材斷面積)의 변화(變化)에 따른 엽중(葉重)과 엽면적(葉面積)의 변화(變化)를 구명(究明)하고자 하였다. 아울러 줄기, 가지, 잎의 분배비율, 줄기에 있어 심재(心材), 변재(邊材), 수피(樹皮)의 분배비율, 수고에 따른 줄기량과 엽량(葉量)의 분포구조 등을 밝히고자 하였다. 얻어진 결과를 요약하면 다음과 같다 l. 줄기, 가지, 잎의 물질생산량(物質生産量)의 평균 분배비율은 건중량(乾重量)을 기준할 때 줄기량이 70-84%로 가장 많고, 가지는 11-25%. 엽량이 3-6%로 가장 적었다. 2. 줄기에 있어 심재(心材), 변재(邊材), 수피(樹皮)의 분배비율은 건중량(乾重量)을 기준으로 할 때 심재(心材)가 37-43%, 변재(邊材)가 38-46%, 수피(樹皮)가 16-19% 이었다. 3. 우세목(優勢木)과 중간목(中間木)에서는 변재량(邊材量)이 심재량(心材量)보다 많았으나, 열세목(劣勢木)에서는 심재량(心材量)이 더 많았다. 4. 줄기의 변재단면적(邊材斷面積)과 엽중(葉重)또는 엽면적(葉面積)과의 관계는 높은 직선상관(直線相關)(r=0.9 이상, 1% 유의(有意))을 나타냈다. 5. 수고(樹高)에 따른 엽면적(葉面積)($m^2$)/변재면적(邊材面積)($cm^2$)의 비(比)인 k값은 0.24-2.05 까지 변화하였다. 6. 가지의 기부직경(基部直徑) 또는 기부단면적(基部斷面積)과 엽중(葉重)또는 엽면적(葉面積)과는 높은 상관(相關)(r=0.9 이상, 1% 유의(有意))을 갖는 직선식(直線式)을 나타냈다. 7. 수고(樹高)에 따른 우세목(優勢木), 중간목(中間木), 열세목(劣勢木)의 엽량(葉量)은 정규분포(正規分布)를 나타냈고, 누적(累積) 간재적량(幹材積量)은 심한 첨형분포(尖形分布)를 나타냈다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권16호
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• pp.7085-7088
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• 2015

Background: The high incidence of prostate cancer as the most common malignancy in males in many countries raises the question of developing reliable detection tests. The prostate specific antigen (PSA) test is the most widely used for screening for prostate cancer; however, its low specificity elevates the number of unnecessarily biopsies. Serum human kallikrein-2 (hK2) is considered as a promising marker, and especially its ratio to fPSA, for predicting the presence of malignancy to select the best choice referring to biopsy or surveillance. In this study, we investigated the role of hK2 and its combinations with other markers to discriminate prostate cancer from benign diseases in Syrian patients. Materials and Methods: In this prospective oriented cross-sectional cohort study, serum samples were collected from patients referred to many Hospitals in Damascus, Syria, between May 2011 and March 2012, and diagnosed with biopsy proven benign prostate hyperplasia (BPH) or prostate cancer (PCa). Serum was analyzed for hK2, PSA and fPSA, and the ratios of fPSA/PSA and hK2/fPSA were calculated. Results: We found that mean hK2/fPSA ratios were significantly higher (P=0.01) in prostate cancer patients than in the BPH or control groups. Also the ratio hk2/fPSA gave the largest area under the curve (AUC:0.96) which was significantly larger than for fPSA/PSA (AUC:0.41) indicative of higher specificity. Conclusions: Our results demonstrate that the ratio of hK2/fPSA might be superior to the use of fPSA/PSA alone. The hK2 could be shown to enhance the early detection of prostate cancer; especially the ratio hK2/fPSA improves specificity and hence may reduce the number of negative biopsies.