• Korean Journal of Occupational Health Nursing
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• v.26 no.4
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• pp.247-260
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• 2017

Purpose: The purpose of this study was to investigate the individual and working environment-related factors affecting hypertension among middle-aged and elderly self-employed workers in South Korea. Methods: This was a secondary data analysis of data from the Korean Longitudinal Study of Aging (KLoSA). The study sample included 1,319 middle-aged and elderly self-employed workers who were diagnosed without hypertension and older than 45 years at Wave 1 of the KLoSA. Data were analyzed using descriptive statistics and Cox proportional hazards regression analysis using SPSS 20.0. Results: About 20% of the middle-aged and elderly self-employed workers were diagnosed with hypertension within about 8 years from the baseline. the significant predictors of hypertension among the participants were age, diabetes mellitus, body mass index, frequency of health examinations, working hours per week, the presence of regular day off, and the type of job. Conclusion: Middle-aged and elderly self-employed workers are vulnerable to work-related health problems. In order to prevent hypertension among self-employed workers, it is necessary to improve the work environment-related factors as well as individual life styles.

• Childhood Kidney Diseases
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• v.12 no.1
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• pp.105-110
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• 2008

Renovascular hypertension results from a lesion that impairs blood flow to a part of or all, of one or both kidneys. Renal artery stenosis is the major cause of renovascular hypertension and the most common cause of treatable secondary hypertension. Recently, percutaneous transluminal renal angioplasty(PTRA) with or without stent placement, has become the preferred choice for correcting symptomatic renal artery stenosis since it is less invasive than surgical reconstruction. PTRA with balloons designed for the dilatation for the dilatation of the coronary artery can be tried in small sized renal artery stenosis. We report a case of renovascular hypertension in a 13-year-old male who had small sized renal artery stenosis. Hypertension was controlled by PTRA with balloon dilatation.

• Korean Journal of Adult Nursing
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• v.29 no.1
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• pp.22-31
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• 2017

Purpose: The purposes of this secondary analysis study was to examine prevalence, risk factors and unmet healthcare needs among adults with hypertension. Methods: A sample of 3,386 adults over the age of 40 with hypertension were drawn from the Korea Health Panel Study (2013). Using SPSS 22.0 version, descriptive statistics including frequency, percentage, chi-square and logistic regression were performed. Results: Results showed that 18.9% of the sample reported unmet healthcare needs with the most frequently cited one was financial burdens (43.2%). The reported experiences of unmet healthcare needs differed by gender, marital status, vision or hearing impairment, memory problem, impaired mobility, subjective health status, total family income, depressive episode and the difficulty in making decisions. The sample participants were more likely to report unmet healthcare if they had vision impairment, low income and perception that their health status as moderate to poor. Those without vision impairment were less likely to report unmet healthcare needs. Conclusion: The identified risk factors of unmet healthcare needs should be addressed which would enhance access both to health care and to resolution of unmet healthcare needs. Since visual ability seems to impact perception of unmet healthcare needs, it may be useful to find ways to address this factor.

• Research in Community and Public Health Nursing
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• v.25 no.3
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• pp.159-169
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• 2014

Purpose: The purpose of this study was to evaluate the effectiveness of case management for patients with hypertension on their health status and medical service utilization. Methods: This study was a secondary analysis of data collected for a larger study of chronic disease management in 2008 using the National Health Insurance Corporation database. A total of 12,944 patients who received case management for hypertension were included in this analysis. The subjects of case management were classified into subgroups, namely, over-use, under-use, and non-use groups according to the amount of medical service utilization. To compare the medical service utilization, a control group was selected randomly. The data were analyzed through descriptive statistics, McNemar test, and ANOVA. Results: All the subgroups displayed significant differences in blood pressure, self-management, social support, and their characteristics of medical service utilization. The total medical expense of the under-use and non-use groups increased after case management. However, there was no decrease in the medical expense of the over-use group. Conclusion: This finding suggests that there is a need to re-examine why patients overuse medical services and to supplement specific strategies for encouraging appropriate medical service utilization, and enhancing case management efforts for the over-use group.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.3
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• pp.740-743
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• 2009

Hypertension is one of the modifiable risk factors for stroke and heart disease. Lowering blood pressure is a primary or secondary preventative measure for stroke and heart disease. There are many antihypertension drugs. But these day there comes some side effect of antihypertension drugs. Headache, sexual dysfunction, inertia, dizziness, depression, and so on. So we use Bangpungtongsung -san to stage 1 hypertensive patients. After treatment with Bangpungtongsung-san, patients showed antihypertensive effect and improvement in general condition. The result of this study suggest that Bangpungtongsung-san might be usefully applied for the treatment of hypertension.

• The Korean Journal of Applied Statistics
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• v.33 no.5
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• pp.555-567
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• 2020

Hypertension has a steadily increasing incidence rate as well as represents a risk factors for secondary diseases such as cardiovascular disease. Therefore, it is important to predict the incidence rate of the disease. In this study, we constructed nomograms that can predict the incidence rate of hypertension. We use data from the Korean National Health and Nutrition Examination Survey (KNHANES) for 2013-2016. The complex sampling data required the use of a Rao-Scott chi-squared test to identify 10 risk factors for hypertension. Smoking and exercise variables were not statistically significant in the Logistic regression; therefore, eight effects were selected as risk factors for hypertension. Logistic and Bayesian nomograms constructed from the selected risk factors were proposed and compared. The constructed nomograms were then verified using a receiver operating characteristics curve and calibration plot.

• Physical Therapy Rehabilitation Science
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• v.12 no.2
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• pp.80-91
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• 2023

Objective: The purpose of this study is to identify factors that affect the incidence of hypertension using logistic regression and decision tree analysis, and to build and compare predictive models. Design: Secondary data analysis study Methods: We analyzed 9,859 subjects from the Korean health panel annual 2019 data provided by the Korea Institute for Health and Social Affairs and National Health Insurance Service. Frequency analysis, chi-square test, binary logistic regression, and decision tree analysis were performed on the data. Results: In logistic regression analysis, those who were 60 years of age or older (Odds ratio, OR=68.801, p<0.001), those who were divorced/widowhood/separated (OR=1.377, p<0.001), those who graduated from middle school or younger (OR=1, reference), those who did not walk at all (OR=1, reference), those who were obese (OR=5.109, p<0.001), and those who had poor subjective health status (OR=2.163, p<0.001) were more likely to develop hypertension. In the decision tree, those over 60 years of age, overweight or obese, and those who graduated from middle school or younger had the highest probability of developing hypertension at 83.3%. Logistic regression analysis showed a specificity of 85.3% and sensitivity of 47.9%; while decision tree analysis showed a specificity of 81.9% and sensitivity of 52.9%. In classification accuracy, logistic regression and decision tree analysis showed 73.6% and 72.6% prediction, respectively. Conclusions: Both logistic regression and decision tree analysis were adequate to explain the predictive model. It is thought that both analysis methods can be used as useful data for constructing a predictive model for hypertension.

• Clinical and Experimental Pediatrics
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• v.56 no.2
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• pp.52-59
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• 2013

Cardiomyopathy (CMP) is a heterogeneous disease caused by a functional abnormality of the cardiac muscle. CMP is of 2 major types, dilated and hypertrophic, and is further classified as either primary or secondary. Secondary CMP is caused by extrinsic factors, including infection, ischemia, hypertension, and metabolic disorders. Primary CMP is diagnosed when the extrinsic factors of secondary CMP are absent. Furthermore, the World Health Organization, American Heart Association, and European Cardiology Association have different systems for clinically classifying primary CMP. Primary CMP is rare and associated with a family history of the disease, implying that genetic factors might affect its incidence. In addition, the incidence of CMP varies widely according to patient ethnicity. Genetic testing plays an important role in the care of patients with CMP and their families because it confirms diagnosis, determines the appropriate care for the patient, and possibly affects patient prognosis. The diagnosis and genetic identification of CMP in patients' families allow the possibility to identify novel genes that may lead to new treatments. This review focuses on the epidemiology, pathophysiology, diagnosis, and treatment of CMP, with the aim of providing pediatricians with insights that may be helpful in the early identification and management of idiopathic CMP in children.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.3
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• pp.353-360
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• 2017

Several human diseases have been associated with mitochondrial voltage-dependent anion channel-1 (VDAC1) due to its role in calcium ion transportation and apoptosis. Recent studies suggest that VDAC1 may interact with endothelium-dependent nitric oxide synthase (eNOS). Decreased VDAC1 expression may limit the physical interaction between VDAC1 and eNOS and thus impair nitric oxide production, leading to cardiovascular diseases, including pulmonary arterial hypertension (PAH). In this report, we conducted meta-analysis of genome-wide expression data to identify VDAC1 influenced genes implicated in PAH pathobiology. First, we identified the genes differentially expressed between wild-type and Vdac1 knockout mouse embryonic fibroblasts in hypoxic conditions. These genes were deemed to be influenced by VDAC1 deficiency. Gene ontology analysis indicates that the VDAC1 influenced genes are significantly associated with PAH pathobiology. Second, a molecular signature derived from the VDAC1 influenced genes was developed. We suggest that, VDAC1 has a protective role in PAH and the gene expression signature of VDAC1 influenced genes can be used to i) predict severity of pulmonary hypertension secondary to pulmonary diseases, ii) differentiate idiopathic pulmonary artery hypertension (IPAH) patients from controls, and iii) differentiate IPAH from connective tissue disease associated PAH.

• Journal of Preventive Medicine and Public Health
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• v.7 no.2
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• pp.395-401
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• 1974

In order to figure out the normal range, lower limit of hypertension and upper limit of hypotension of the blood pressure of Korean, authors had measured blood pressure according to Korotkow's method for 31,897 healthy persons as samples who were occupied different levels of the social class except cases who would seem to be the essential hypertension and had the diseases affecting to secondary hypertension. A following conclusion was induced by actual measurement and statistical reasoning. 1. The normal range and limits of hypo- and hypertension by sex and age groups of Korean were demonstrated in Table 1 and Figure 1. 2. The more aging the higher value of blood pressure in both sexes, especially women rather than men and systolic as to diastolic. 3. Generally, blood pressure values of female were lower than male, after 55 years of age, however, the crossing phenomenon was recognizable. 4. To settle the normal and abnormal ranges of the blood pressure of Korean, it was attempted that $M{\pm}1.282{\sigma}$ as normal range, $M+2{\sigma}$ as lower limit of hypertension and $M-2{\sigma}$ as upper limit of hypotension were calculated, and regression lines were drawn to adjust the biological variables and derive continuity from each age class. (Fig. 2 and 3) 5. The blood pressure levels were becoming elevated as to getting increased of the body weight, particularly diastolic value at 40-49 age group in male and systolic value at 30-39 age group in female.