• Title/Summary/Keyword: Secondary Flow Rate

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Studies of Cyclosporin A Biosynthesis under the Conditions of Limited Dissolved Oxygen or Carbon Source in Fed-batch Culture (용존산소 제한 또는 탄소원 제한 조건의 유가식배양에서의 Cyclosporin A 생합성 연구)

  • 전계택;박성관;권호균;정연호;정용섭;장용근;이영행
    • KSBB Journal
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    • v.13 no.2
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    • pp.203-208
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    • 1998
  • We investigated the effects of dissolved oxygen (D.O.) and fructose (C-source) on cell growth and biosynthesis of cyclosporin A (CyA) produced as a secondary metabolite by a wild-type filamentous fungus, Tolypocladium inflatum. This was performed by controlling the level of D.O. and the residual C-source, as required, through adjustment of medium flow rate, medium concentration and agitation rate in fed-batch cultures. CyA production was furned out to be maximal, when D.O. level was controlled around 10% saturated D.O. and concentration of the C-source was maintained sufficiently low (below 2 g/L) not to cause carbon catabolite repression. Under this culture condition, we obtained the highest values of CyA concentration (507.14 mg/L), Qp (2.11 mg CyA/L/hr), $Y_x/s$ (0.49 g DCW/g fructose), $Y_p/s$<(22.56 mg CyA/g fructose), and YTEX>$_p/x$ (48.31 mg CyA/g DCW), but relatively lower values of cell concentration (11.98 g DCW/L) and cell productivity (0.043 g DCW/L/hr), in comparison with other parallel fed-batch fermentation conditions. These results implied that, in the carbon-limited culture with 10% saturated D.O. level, the producer microorganism utilized the C-source more efficiently for secondary metabolism.

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Evaluation of water treatment characteristics at the improved circle secondary settling basin (개량 고속원형침전지의 수처리 특성 평가)

  • Jang, Honggyu;Cho, Youngman;Kim, Changwon
    • Journal of Korean Society of Water and Wastewater
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    • v.28 no.5
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    • pp.609-614
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    • 2014
  • Researcher of this study improved conventional circle secondary settling basin, through the way such as extend of inlet pipe length, introduction of device for inducting uniforming of flow, keeping of height of sludge interface. Also, we compared conventional circle settling basin to improved circle settling basin the water treatment efficiency. Result of research, when SVI is average 117, improvement rate of SS and BOD were 51.0%, 37.0% approximately compared to conventional settling basin. And when SVI is average 178, improvement rate of SS and BOD were 22.7%, 36.0% approximately. Also when SVI is average 196, improvement rate of SS and BOD were 24.7%, 30.3% approximately. When it's winter, improvement rate of SS, BOD, COD, TN and TP were 20.6%, 17.9%, 13.9%, 13.5%, 12.4% approximately. Therefore, we can be the judge, this improved settling basin can be used as the final settling basin in the waste water treatment plant.

A Characteristics of a Secondary flow in a Corner Section of Square Duct (정사각덕트의 코너부에서 이차유동 특성)

  • Joung, J.M.;Kim, J.H.;Yoo, Y.T.
    • Proceedings of the KSME Conference
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    • 2000.04b
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    • pp.753-758
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    • 2000
  • Heat engine and fluid machinery in the plant have to linked with various ducts network and the corresponding design have to be concerned about effectiveness and stability of system of plant. To optimum control and design system concerning stability, economization, operating effectiveness we have to exact analysis flow properties of a duct applying to fluid machinery, heat exchanger, cooling machine, air conditioning equipment. therefore, it is necessary to research the duct, heat transfer equipment, for increasing overall effectiveness of air conditioning system by suggesting basic data of the duct resulting from organic research. So we can contribute to technical development of the duct. In case of speeding up the flow rate of the duct, lots of wave velocity components are occurred the value of boundary layer resulting from developing the boundary layer at both walls of duct.

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Experimental Study on Flows within an Unshrouded Centrifugal Impeller Passage(I)-At the Shockless Condition- (개방형 원심회전차의 내부유동장에 관한 실험적 연구(1)-무충돌 유입조건에서-)

  • 김성원;조강래
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.19 no.9
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    • pp.2261-2270
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    • 1995
  • Flow patterns were measured in an unshrouded centrifugal impeller. The flow rate in measurements was fixed at the value corresponding to a nearly zero incidence at the blade inlet. By using a single slanted hot-wire probe and a Kiel probe mounted on the impeller hub disk, the 3-D relative velocities and the rotary stagnation pressures were measured in seven circumferential planes from the inlet to the outlet of the impeller rotating at 700rpm, which diameter is 0.39 meter, and the static pressures and the slip factor at the impeller outlet were calculated from the measured values. From the measured data, the primary/secondary flows, the leakage flows, the wake-jet flows, static pressure distribution on blade surfaces and the wake production mechanism in the impeller passage were investigated.

Analysis of Mining Performance and Flow Measurement Inside a Micro Mixer (마이크로 혼합기 내의 유동 계측 및 혼합 특성 해석)

  • Sung Jaey-ong;Lee In-won;Kim Byoung-Gyun;Yoon Eui-sik;Lee In-Seop
    • 한국가시화정보학회:학술대회논문집
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    • 2002.11a
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    • pp.45-48
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    • 2002
  • To investigate the flow related to the mixing, micro PIV measurements were performed in the middle plane of the channel. A passive micro mixer analyzed in this work has been designed in the shape of a three-dimensional microchannel and fabricated with PDMS molding process by KAIST. The mixing performance was evaluated for different flow rates using phenolphthalein and sodium hydroxide solutions. Results show that mixing is enhanced by the increase of flow rate, which yields stronger secondary flows with helical streamlines.

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A Study of the Thrust Vectoring Control Using Secondary Co- and Counter-Streams (2차 순유동과 역유동을 이용한 추력벡터 제어법에 관한 연구)

  • Lim Chae-Min;Kim Heuy-Dong
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2004.10a
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    • pp.109-112
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    • 2004
  • Of late, the thrust vectoring control, using fluidic co-flow and counter-flow concepts, has been received much attention since it not only improves the maneuverability of propulsive engine but also reduces an additional material load due to the trailing control wings, which in turn reduce the aerodynamic drag. However, the control effects are not understood well since the flow field involves very complicated non: physics such as shock wave/boundary layer interaction, separation and significant unsteadiness. Existing data are not enough to achieve the effectiveness and usefulness of the thrust vectoring control, and systematic work is required for the purpose of practical applications In the present study, computational study has been performed to investigate the effects of the thrust vector control using the fluidic co-and counter-flow concepts. The results obtained show that, for a given pressure ratio, the thrust deflection angle has a maximum value at a certain suction flow rate, which is at less than $5\%$ of the mass flow rate of the primary jet. With a longer collar, the same vector angle is achievable with smaller mass flow rate.

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Wear Characteristics of Multi- span Tube Due to Turbulence Excitation (다경간 전열관의 난류 가진에 의한 마모특성 연구)

  • Kim, Hyung-Jin;Sung, Bong-Zoo;Park, Chi-Yong;Ryu, Ki-Whan
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.16 no.9 s.114
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    • pp.904-911
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    • 2006
  • A modified energy method for the fretting wear of the steam generator tube is proposed to calculate the wear-out depth between the nuclear steam generator tube and its support. Estimation of fretting-wear damage typically requires a non-linear dynamic analysis with the information of the gap velocity and the flow density around the tube. This analysis is very complex and time consuming. The basic concept of the energy method is that the volume wear rate due to the fretting-wear phenomena Is related to work rate which is time rate of the product of normal contact force and sliding distance. The wearing motion is due to dynamic interaction between vibrating tube and its support structure, such as tube support plate and anti-vibration bar. It can be assumed that the absorbed work rate would come from turbulent flow energy around the vibrating tube. This study also numerically obtains the wear-out depth with various wear topologies. A new dissection method is applied to the multi-span tubes to represent the vibrational mode. It turns out that both the secondary side density and the normal gap velocity are important parameters for the fretting-wear phenomena of the steam generator tube.

Capacity Modulation of a Multi-Type Heat Pump System Using PID Control (PID 제어를 이용한 멀티형 열펌프의 용량조절)

  • 정대성;김민성;김민수;이원용
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.12 no.5
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    • pp.446-475
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    • 2000
  • Performance of a water-to-water multi-type heat pump system using R22 has been experimentally investigated. Total refrigerant flow rate was adjusted with a variable speed compressor and the refrigerant flow rate for two indoor units were controlled by electronic expansion valves. Evaporator outlet pressure of refrigerant and indoor unit outlet temperatures of secondary fluid were selected as controlled variables. Experiments were carried out for both cooling and heating modes using PID control method. Results show that the multi-type heat pump system can be adequately controlled by keeping control gains at certain levels for various operating conditions.

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Optimization of inlet velocity profile for uniform epitaxial growth (균일한 에피층 성장을 위한 입구 유속분포 최적화)

  • Cho W. K.;Choi D. H.;Kim M.-U.
    • 한국전산유체공학회:학술대회논문집
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    • 1998.11a
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    • pp.121-126
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    • 1998
  • A numerical optimization procedure is developed to find the inlet velocity profile that yields the most uniform epitaxial layer in a vertical MOCVD reactor. It involves the solution of fully elliptic equations of motion, temperature, and concentration; the finite volume method based on SIMPLE algorithm has been adopted to solve the Navier-Stokes equations. The overall optimization process is highly nonlinear and has been efficiently treated by the sequential linear programming technique that breaks the non-linear problem into a series of linear ones. The optimal profile approximated by a 6th-degree Chebyshev polynomial is very successful in reducing the spatial non-uniformity of the growth rate. The optimization is particularly effective to the high Reynolds number flow. It is also found that a properly constructed inlet velocity profile can suppress the buoyancy driven secondary flow and improve the growth-rate uniformity.

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Effects of Oxygen on the Properties of Mg-doped Zinc Tin Oxide Films Prepared by rf Magnetron Sputtering (rf 마그네트론 스퍼터링으로 증착한 Mg-doped Zinc Tin Oxide막의 특성에 미치는 산소의 영향)

  • Park, Ki Cheol;Ma, Tae Young
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.26 no.5
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    • pp.373-379
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    • 2013
  • Mg-doped zinc tin oxide (ZTO:Mg) thin films were prepared on glasses by rf magnetron sputtering. $O_2$ was introduced into the chamber during the sputtering. The optical properties of the films as a function of oxygen flow rate were studied. The crystal structure, elementary properties, and depth profiles of the films were investigated by X-ray diffraction (XRD), x-ray photoelectron spectroscopy (XPS), and secondary ion mass spectrometry (SIMS), respectively. Bottom-gate transparent thin film transistors were fabricated on $N^+$ Si wafers, and the variation of mobility, threshold voltage etc. with the oxygen flow rate were observed.