• Title/Summary/Keyword: Secondary Disease

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Benefits and risks of therapeutic alternatives for macrolide resistant Mycoplasma pneumoniae pneumonia in children

  • Yang, Hyeon-Jong
    • Clinical and Experimental Pediatrics
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    • v.62 no.6
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    • pp.199-205
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    • 2019
  • Although Mycoplasma pneumoniae pneumonia (MPP) has been generally susceptible to macrolides, the emergence of macrolide-resistant MPP (MRMP) has made its treatment challenging. MRMP rapidly spread after the 2000s, especially in East Asia. MRMP is more common in children and adolescents than in adults, which is likely related to the frequent use of macrolides for treating M. pneumoniae infections in children. MRMP is unlikely to be related to clinical, laboratory, or radiological severity, although it likely prolongs the persistence of symptoms and the length of hospital stay. Thereby, it causes an increased burden of the disease and poor quality of life for the patient as well as a societal socioeconomic burden. To date, the only alternative treatments for MRMP are secondary antimicrobials such as tetracyclines (TCs) or fluoroquinolones (FQs) or systemic corticosteroids; however, the former are contraindicated in children because of concerns about potential adverse events (i.e., tooth discoloration or tendinopathy). A few guidelines recommended TCs or FQs as the second-line drug of choice for treating MRMP. However, there have been no evidence-based guidelines. Furthermore, safety issues have not yet been resolved. Therefore, this article aimed to review the benefits and risks of therapeutic alternatives for treating MRMP in children and review the recommendations of international or regional guidelines and specific considerations for their practical application.

Working Conditions and Health Status of Delivery Workers (배달종사자의 근로환경과 건강)

  • Lee, Bokim
    • Korean Journal of Occupational Health Nursing
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    • v.28 no.3
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    • pp.156-165
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    • 2019
  • Purpose: The purpose of this study was to compare working condition and health status between parcel delivery workers (PDW) and food delivery workers (FDW) and to examine the factors influencing their health status. Methods: This was a secondary analysis of data collected from the fifth Korean Working Conditions Survey (KWCS). Based on existing literature, a set of variables was chosen from the KWCS. Results: The proportion of PDW who carryied/moved heavy loads and experienced high job stress and lack of rest time was significantly higher than that of FDW. However, more FDW than their counterparts worked atypical hours. The differences in fatigue and well-being between PDW and FDW were not statistically significant. The multiple logistic regression analysis revealed low temperature, tobacco smoke, standing for long periods, and job stress were significant predictors of fatigue or well-being of FDW. Among PDW, noise, tobacco smoke, sitting for long periods, quantitative demands, hiding emotions, support from colleagues, job stress, no recovery period, and night work were significant predictors of fatigue or well-being. Conclusion: The findings of this study may be useful in developing nursing interventions for disease protection health promotion of delivery workers.

Evaluation of the Effectiveness and the Level of Self-Management Support on the Metabolic Syndrome Management Program at Public Health Centers in Seoul Metropolitan City (서울시 보건소 대사증후군관리사업의 효과와 자가관리 지원수준 평가)

  • Kim, Dong-Ok
    • Health Policy and Management
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    • v.29 no.1
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    • pp.19-26
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    • 2019
  • Background: The purpose of this study was to evaluate the effectiveness and the level of self-management support on the Metabolic Syndrome Management Program at public health centers in Seoul metropolitan city. Methods: The effectiveness on the Metabolic Syndrome Management Program were analyzed using secondary data from 1,312 community residents who were receiving program. The level of self-management support on Metabolic Syndrome Management Program was evaluated using an 'Assessment of Primary Care Resources and Supports for Chronic Disease Self-Management' from four public health centers. Results: The effectiveness on the Metabolic Syndrome Management Program was showed that decreased smoking (p= 0.044) and drinking (p< 0.001), and increased healthy dietary habit (p< 0.001) in health behaviors. It was showed that decreased triglyceride (p= 0.002) and increased high-density lipoprotein cholesterol (p< 0.001) in clinical indicators. The level of self-management support on Metabolic Syndrome Management Program was 98.1 points and it meaned that implementation is done in an organized and consistent manner using a team approach. There was difference in the level of self-management support by public health centers (p= 0.003). Conclusion: The Metabolic Syndrome Management Program in public health centers was effective, and level of self-management support was done as organizational level, but patient input and mental health were insufficient.

Psychosocial Factors Associated with Metabolic Syndrome among Korean Men and Women Aged over 40 Years (40세 이상 성인 남녀의 대사증후군 관련 심리사회적 요인)

  • Ra, Jin Suk;Kim, Hye Sun
    • Journal of Korean Public Health Nursing
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    • v.33 no.1
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    • pp.20-32
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    • 2019
  • Objectives: This study identified biopsychosocial factors associated with metabolic syndrome among Korean men and women aged over 40 years. Methods: Secondary data from the 2010-2016 Korean National Health and Nutrition Examination Survey were used for this study. Based on the biopsychosocial model, psychosocial factors (stress, depression, smoking, binge alcohol consumption, physical activity) were assessed with control of biomedical (age, body mass index, family history of hypertension, dyslipidemia, type 2 diabetes mellitus, and cardiovascular disease) and biosocial factors (educational level and economic status). Data from 8,624 men and 7,321 women were analyzed by logistic regression analysis using a complex sample procedure. Results: Among men, current or past smoking habits (Adjusted Odds Ratio [AOR]: 1.349; 95% Confidence Interval [CI]: 1.155-1.575, p<.001) and binge alcohol consumption (AOR: 1.570, CI: 1.389-1.774, p<.001) were associated with metabolic syndrome. In addition, moderate (AOR: 1.205, CI: 1.038-1.400, p=.014) and low levels of physical activity (AOR: 1.296, CI: 1.109-1.514, p=.001) were associated with metabolic syndrome. Among women, low level of physical activity (AOR: 1.276, CI: 1.017-1.602, p=.036) was associated with metabolic syndrome. Conclusion: Gender specific interventions such as encouraging physical activity and prevention of smoking and excessive alcohol drinking are important to prevention of metabolic syndrome.

Factors Affecting the Depressive Mood Experience in University Students by Gender in COVID-19 Pandemic Situation: Using Community Health Survey Data for 2020 (코로나19 팬데믹 상황에서 성별에 따른 대학생의 우울감 경험에 영향을 미치는 요인: 2020 지역사회건강조사 자료 활용)

  • Kim, Kyung Sook
    • Health Policy and Management
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    • v.31 no.3
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    • pp.374-383
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    • 2021
  • Background: The purpose of this study is to identify the factors affecting the depressive mood experience in university students by gender. Methods: This study is a descriptive survey that conducted a secondary analysis using data from the 2020 Community Health Survey, which is conducted annually in Korea. The study targets 8,928 college students, 4,682 male students and 4,246 female students. Data analysis was conducted after creating a composite sample plan file that reflected layering variables, colony variables, and weights. Results: Factors affecting the depressive mood experience of both males and females were household income, smoking, subjective stress levels, changes in drinking and smoking, and the number of encounters caused by coronavirus disease 2019 (COVID-19). Factors influencing the depressive mood experience of females were the presence of breakfast, changes in physical activity due to COVID-19, and the presence of helpers in self-quarantine due to COVID-19 (p<0.05). Conclusion: Psychological counseling programs should be promoted to actively utilize mental health in those in their 20s and 30s. Universities also need to detect depressed students early through screening and perform timely and appropriate interventions.

Factors influencing health behavior of residents in Lao People's Democratic Republic: Focusing on mediating effect of health locus of control (라오스 주민의 건강행위에 영향을 미치는 요인: 건강통제위 매개효과를 중심으로)

  • Lee, Mee Sun;Lee, Gun Jeong
    • Journal of Korean Public Health Nursing
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    • v.35 no.2
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    • pp.268-282
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    • 2021
  • Purpose: This study sought to investigate health behavior (HB) and its affecting factors based on Anderson's behavioral model in Lao People's Democratic Republic (PDR). Also, it attempted to identify the mediation of the health locus of control (HLC) between HB and the affecting factors. Methods: Secondary data from 694 people without noncommunicable diseases (NCDs) from a survey conducted by the Ewha Womans and the Laos University were used. The measurements included predisposing, enabling, and needs factors, HLC, HB (current non-smoking, low-risk drinking, physical activity, fruit and vegetable consumption, medical checkup). The mediating effect was analyzed using Baron and Kenny's method and the Sobel test. Results: Predisposing (gender, educational level, ethnic), enabling (social support, item ownership in household) and the needs factors (body mass index) were affecting HB. Internal HLC had a positive influence on HB. The stronger the others and chance HLC, the lower the HB. Chance HLC mediated the relationship between the educational level and HB. Conclusion: There is a need to recognize the importance of chance HLC as a mediator between the educational level and HB. Through this result, high-quality nursing education for the prevention of NCDs should be developed considering the impact of chance HLC.

Molecular Perspectives of SARS-CoV-2: Pathology, Immune Evasion, and Therapeutic Interventions

  • Shah, Masaud;Woo, Hyun Goo
    • Molecules and Cells
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    • v.44 no.6
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    • pp.408-421
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    • 2021
  • The outbreak of coronavirus disease 2019 (COVID-19) has not only affected human health but also diverted the focus of research and derailed the world economy over the past year. Recently, vaccination against COVID-19 has begun, but further studies on effective therapeutic agents are still needed. The severity of COVID-19 is attributable to several factors such as the dysfunctional host immune response manifested by uncontrolled viral replication, type I interferon suppression, and release of impaired cytokines by the infected resident and recruited cells. Due to the evolving pathophysiology and direct involvement of the host immune system in COVID-19, the use of immune-modulating drugs is still challenging. For the use of immune-modulating drugs in severe COVID-19, it is important to balance the fight between the aggravated immune system and suppression of immune defense against the virus that causes secondary infection. In addition, the interplaying events that occur during virus-host interactions, such as activation of the host immune system, immune evasion mechanism of the virus, and manifestation of different stages of COVID-19, are disjunctive and require thorough streamlining. This review provides an update on the immunotherapeutic interventions implemented to combat COVID-19 along with the understanding of molecular aspects of the immune evasion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which may provide opportunities to develop more effective and promising therapeutics.

Life Satisfaction of College Students with Allergic disease (알러지 질환 대학생의 삶의 만족도에 관한 연구)

  • Lee, Seonhye
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.1
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    • pp.502-510
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    • 2021
  • This study was identified to affection factors the life satisfaction among the college students with allergies by ecological approaches. This study was secondary analysis by using the 2015 Korean Community Health Survey (CHS) raw data, it analyzed 1,862 college students with allergies. Male students' life satisfaction were explained by 7.9% as degree of allergic diseases, frequency of breakfast, networking with friends, social activities with relatives, social activities with religion, satisfaction of natural environment and medical health service. Female students' life satisfaction were explained by 3.0% as frequency of breakfast meal, social activities with relatives and satisfaction of natural environment. We need to make the strategies and policies to improve of student's intake breakfast and make campus' green space.

Factors Affecting Income from Public Agricultural Land Use: An Empirical Study from Vietnam

  • PHAM, Phuong Nam;TRAN, Thai Yen
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.6
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    • pp.1-9
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    • 2022
  • The study aims to determine the factors and their influence on the income from using public agricultural land of households. Public agricultural land is agricultural land, including land for growing annual crops, perennial crops, and land for aquaculture, leased by commune-level People's Committees with a lease term of not more than 5 years. Secondary data were collected for the 2017-2021 period at state agencies. Primary data were collected from a survey of 150 households renting public agricultural land. The regression model assumed that there were 28 factors belonging to 7 groups. The test results show that 25 factors affect income, and 03 factors do not. The group of COVID-19 pandemic factors has the strongest impact, followed by the groups of agricultural product market factors, land factors, capital factors, production cost factors, labor factors, and climatic factors. The impact rate of COVID-19 pandemic factors is the largest (23.00%); The impact rate of climatic factors is the smallest (6.04%). Proposals to increase income include good implementation of disease prevention and control; increasing the land lease term; accurately forecasting the supply and demand of the agricultural market; raising the level of the household head; ensuring sufficient production capital, and adapting to the climate.

Association between age at menarche, oral health behavior and oral health status (초경연령과 구강건강행태 및 구강건강상태와의 관련성)

  • Kim, In-Ja
    • Journal of Korean society of Dental Hygiene
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    • v.22 no.1
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    • pp.29-36
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    • 2022
  • Objectives: This study aimed to examine the association between age at menarche and two major oral diseases. Methods: Data from the 7th Korean National Health and Nutrition Examination Survey (2016-2018) were used. The participants included girls and women aged 12 years and above. Thedataofa total of 7,420 participants were analyzed. Statistical analyses were performed using complex samples cross-tabulation analysis and complex samples general linear model. Results: The average age at menarche of those aged 12 to 80 years was 13.81 years. The age at menarche was found to be associated with decayed-missing-filled teeth (DMFT) (p<0.05). When the age at menarche was nine years, DMFT was 4.20 when it was 19 years, DMFT was 10.80. The age at menarche was found to be associated with periodontal tissue state (p<0.05). The group with early menarche age had healthier periodontal tissues (17.1%), whereas the group with late menarche age had more unhealthy periodontal tissues (17.9%) (p<0.001). Conclusions: The age at menarche was associated with two major oral diseases. Therefore, it is necessary to provide women with oral hygiene care and oral health education to prevent major oral diseases before their secondary sex characteristics appear.