• 제목/요약/키워드: Second Primary

검색결과 1,914건 처리시간 0.024초

다발성 원발성 악성 종양 - 121 예의 임상적 분석- (Incidence and Significance of Multiple Primary Malignant Neoplasms)

  • 최은경;조문준;하성환;박찬일;방영주;김노경
    • Radiation Oncology Journal
    • /
    • 제4권2호
    • /
    • pp.129-133
    • /
    • 1986
  • 한 환자에서 두개 이상의 중복암이 발생하는 경우는 매우 드물게 알려져 왔으나 근래에 들어와 치료법의 발달로 환자의 수명이 연장되고 진단법이 발달되면서 그 보고가 증가되고 또한 관심도 높아지고 있는 상태이다. 따라서 이런 중복암을 가진 환자의 특성을 분석함으로써 발생할 수 있는 2차 3차 암의 조기 발견 및 나아가서는 발암 물질과 유전적 요인 등을 찾아 암의 치료 및 예방에 이응 할 수 있겠다. 이에 $1978.7\~1986.8$까지 8년간 서울 대학교 병원에서 중복암으로 진단되어 치료받은 121예를 대상으로 하여 다음과 같은 결과를 얻었다. 전체 발생율은$0.7\%$이 있으며 이중 2중복암이 119례, 3중복암이 2례 있었다. 동시성은 (6개월 이내) 51례, 속발성은 (6개월 이상) 70례이었으며 속발성의 경우 $70\%$이상에서 3년내에 2차 암이 발생했다. Moertel분류에 의한 mvlticentriz은 $11.6\%$로 다소 낮은 빈도를 보였으며 다른 장기에 발생한 중복암 중에서는 위암과 간암, 위암과 직장암의 빈도가 가장 높았다.

  • PDF

Clinical Features of Molar Root-Incisor Malformation: A Retrospective Study

  • Sejin Chun;Hyuntae Kim;Ji-Soo Song;Teo Jeon Shin;Hong-Keun Hyun;Jung-Wook Kim;Ki-Taeg Jang;Young-Jae Kim
    • 대한소아치과학회지
    • /
    • 제51권3호
    • /
    • pp.279-289
    • /
    • 2024
  • This study aimed to identify the clinical characteristics of molar root-incisor malformation (MRIM) and provide clinical considerations for treatments. Panoramic radiographs and electronic medical records of 64 patients with MRIM were retrospectively reviewed. Age, gender, follow-up period, medical history, complications, distribution of MRIM teeth, treatment, and prognosis were analyzed. Females were affected 1.56 times more than males, and the average age was 8.2 years. Dental complications, including periapical lesions, abscesses, and alveolar bone loss, were observed in 71.9%, and eruption disturbance of adjacent teeth was noticed in 37.5%. Most patients had medical histories in the first year of life. The most prevalent history was prematurity or low birthweight, followed by neurological conditions, surgeries, medications, and infections. All patients had MRIM on permanent first molars. The primary second molars were the second most frequently involved, followed by maxillary permanent central incisors and primary first molars. The prevalence was low on permanent lateral incisors and canines. Extraction was the most prevalent treatment done on MRIM-affected teeth, and most extraction sockets were managed by the eruption of permanent second molars. Few cases received endodontic treatment but with low success rates. Early detection of MRIM and prompt, appropriate treatment are important to avoid unnecessary discomfort from complications.

변색된 유전치의 순측접근에 의한 치수치료 및 레진수복 (LABIAL APPROACH OF PULP TREATMENT AND RESIN RESTORATION ON DISCOLORED NECROTIC PRIMARY ANTERIOR TOOTH)

  • 채문희;송제선;최형준;김성오
    • 대한장애인치과학회지
    • /
    • 제10권2호
    • /
    • pp.84-88
    • /
    • 2014
  • 1. 순측접근법은 치수치료를 순측으로 시행한 후 변색된 순측의 치질을 확대하여 삭제하고 레진으로 순면전체를 수복함으로써 치수치료와 동시에 심미성을 회복할 수 있다. 2. 순측으로 치수치료를 시행하므로 시야가 확보에 유리하고 기구조작이 용이해 행동조절이 잘 되지 않는 어린이에게 추천된다.

원발성 위암과 후두암, 폐암 병발의 1례 (A Case of Triple Primary Cancers in Stomach, Larynx, and Lung)

  • 최주영;장혜정;이민진;심성신;류연주;문진욱;이진화;천은미;장중현
    • Tuberculosis and Respiratory Diseases
    • /
    • 제61권3호
    • /
    • pp.279-284
    • /
    • 2006
  • 다발성 원발성 악성종양은 최근 발생 빈도가 증가하고 있으며 이는 암의 진단 방법의 개선 및 인구의 고령화, 유해물질에 대한 노출증가에 기인한다. 국내에서도 다발성 원발성 악성종양에 대한 연구가 진행되어왔으며, 김등, 윤등이 보고하였다. 그러나 삼중복암의 발생하는 빈도는 매우 낮은 것으로 보고되어있다. 저자들은 이화여대 동대문 병원 내과에 입원한 다발성 원발성 위암, 후두암, 폐암 환자의 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

농촌다문화 초등학교 학생의 사회적 지지 및 부모-자녀간 의사소통이 정서지능에 미치는 영향 (Effects of Social Support and Parent-Child Communication on Emotional Intelligence of Multicultural Primary School Students in Rural Areas)

  • 이창식;박지영;임인택
    • 농촌지도와개발
    • /
    • 제19권4호
    • /
    • pp.881-904
    • /
    • 2012
  • 이 연구는 농촌 다문화 초등학교 학생들의 발달 과정에서 매우 중요한 사회적지지 및 부모-자녀간의 의사소통과 정서지능과의 관계를 파악하고 이러한 변인들이 일반 및 다문화가정 학생 간에 차이가 있는지를 확인하고자 하였다. 연구결과 첫째, 사회적지지, 개방적 의사소통 및 정서지능 간에는 유의미한 정적 상관관계가 있었으며, 반면 정서지능과 부모-역기능적 의사소통과는 유의미한 상관관계를 보이지 않았다. 둘째, 사회적지지, 부모-자녀 간 의사소통, 정서지능은 농촌소규모 다문화초등학교 일반가정 및 다문화가정 학생 간에 차이가 없었다. 셋째, 회귀분석 결과 농촌다문화 초등학교 학생들의 정서지능은 친구지지와 가족지지가 예측변인으로 나타났다.

경폐(經閉)(무월경(無月經))에 관(關)한 임상적(臨床的) 고찰(考察) (A Clinical Study on Amenorrhoea(經閉) Patients)

  • 이진무;이경섭;송병기
    • 대한한의학회지
    • /
    • 제17권2호
    • /
    • pp.405-417
    • /
    • 1996
  • An amenorrhoea means the pathologic condition that menstruation stops before the post menopausal period. Clinically, this is classified to both primary amenorrhoea and secondary amenorrhoea. Primary amenorrhoea indicate what has no first menstruation until 14 without secondary sexual sign or what has no first menstruation until 16 with secondary sexual sign before the time. Secondary amenorrhoea is diagnosised when a women with normal menstrual cycle before the onset doesn't have a menstruation over 6 months or appeals amenorrhoea for three times of her normal menstrual cycle. This clinical study was done on the patients who had come to gynecology department of oriental Hospital of Kyung Hee Medical Center from August 1, 1994 to July 31, 1995, complaining of amenorrhoea. The results obtained were as follows: 1. The amenorrhoea patient rate among outpatients who came to the deptment of gynecology was 3.4%. 2. The ratio between primary amenorrhoea and secondary amenorrhoea was 1 : 6.5. 33. The patient rate via other hospitals was 75% and Unremarkable finding(47.6%) was most numerous according to other hospital's diagnosis and hyperprolactinemia(11.9%), premature menopause(11.9%) were the second numerous diagnosis. 4. Unremarkable history(56.7%) was most numerous and among history, the fast(weight loss; 30%) was most numerous. 5. The most general symptom of amenorrhoea patient was indigestion(51.7%). 6. The most frequently used prescribtion for non-insurance was Onpojongoktang(溫胞種玉湯 ; 55%), for insurance was Gamisoyosan(加味逍遙散 ; 16.7%). 7. 25% patient show menstruation in their therapy and among this, 80% patient show menstruation within 40 days. 8. 26.9% secondary amenorrhoea patient show menstruation in their therapy and only one primary amenorrhoea patent(12.5%) shows the same result. 9. Among the effective used prescribtion, Onpojongoktang(溫胞種玉湯 ; 46.7%) is most numerous.

  • PDF

간혈관신티그램의 정상성과 간암 및 간농양에서의 변화 (Hepatoscintiangiography of Normal Liver and Its Alteration in Hepatomas and Liver Abscess)

  • 박용휘;정수교
    • 대한핵의학회지
    • /
    • 제20권1호
    • /
    • pp.25-31
    • /
    • 1986
  • This study was performed to establish normal hepatoscintiangiographic(HSA) pattern of hepatic blood flow and to investigate dynamic differential HSA findings of primary and metastatic carcinomas and abscess of the liver. HSA was carried out after intravenous bolus injection of 10 mCi of Tc-99m-phytate by obtaining sequential anterior images of 1-second exposure for 16 seconds. Observations included (1) baseline study of normal hepatic blood flow pattern by correlating with contrast angiogram, (2) time sequence phasing of normal HSA, and (3) analysis of altered patterns in primary and metastatic carcinomas and abscesses of the liver. Materials consisted of 20 normal subjects, 28 primary hepatocellular carcinomas, 16 metastatic carcinomas and 7 liver abscesses. Results were: (1) Normal HSA demonstrated 3 distinct phases of arterialization(AP), of arterial hepatogram(AHP), and of portal venous hepatogram(PVHP). The means of each phase were 5.3, 6.3 and 8.3 seconds, respectively. Portal vein could be seen in all but one of 20 normal subjects. (2) Pattern changes in diseases groups were early start of AP in carcinomas and very early start of AP in abscesses. AP became prolonged in all disease group. (3) Distinction between AHP was sharp in metastasis and abscesses but un sharp in primary hepatoma. Cold area or areas became vascularized in primary hepatoma but not in abscess. Cold areas of metastasis were inhomogeneously vascularized in late AP and throughout AHP and became relatively vascular as PVHP began. The cold area of abscess showed rim enhancement during AH and APH. These differences in HSA pattern were very useful in differential diagnosis of the diseases studied.

  • PDF

유치열기의 외상으로 인한 계승 영구치의 발육 및 맹출장애 (DEVELOPMENTAL AND ERUPTIONAL DISTURBANCES OF PERMANENT SUCCESSORS ASSOCIATED WITH TRAUMATIC INJURY TO PRIMARY TEETH)

  • 임형수;이창섭;이상호
    • 대한소아치과학회지
    • /
    • 제28권2호
    • /
    • pp.255-260
    • /
    • 2001
  • 유치의 외상으로 인해 이환된 유치의 손상뿐만 아니라 형성 중인 계승 영구치의 발육과 맹출에도 영향을 줄 수 있다. 가장 흔한 합병증으로는 법랑질의 변색이나 법랑질 저형성증이며, 드물게 계승 영구치의 매복, 이소성 맹출, 치관 또는 치근 만곡, 치근 형성 정지를 유발할 수도 있다. 본 증례들에서는 유치열에 대한 외상성 손상으로 계승 영구치가 심각한 발육 및 맹출 장애를 보였다. 증례 1에서는 4세 7개월경의 외상으로 인해 상악 우측 유중절치와 상악 우측 유측절치가 측방 탈구되고 증례 2에서는 3세경의 외상으로 상악 우측 유중절치와 유측절치가 완전 탈구되었다. 그 결과 계승 영구치인 상악 우측 중절치와 측절치가 모두 동시에 매복되고 치근형성이 정지되었으며 이소성 맹출이 관찰되었다. 계승 영구치의 발육 장애를 조기에 진단하고 치료하기 위해서는 정기적인 임상 및 방사선학적 검사가 필요하다.

  • PDF

Erlotinib-Related Spontaneous Pneumothorax in Patient with Primary Lung Cancer

  • Nam, Hae-Seong;Lee, Hyeon-Jeong;Kim, Min-Su;Park, Sung-Wook;Jeon, Sang-Hoon;Cho, Jae-Hwa;Kwak, Seung-Min;Lee, Hong-Lyeol;Ryu, Jeong-Seon
    • Tuberculosis and Respiratory Diseases
    • /
    • 제69권6호
    • /
    • pp.465-468
    • /
    • 2010
  • Spontaneous pneumothorax (SPTx) associated with primary lung cancer is quite rare, but has been reported as the initial presentation or a complication of disease progression. Moreover, chemotherapy-related SPTx in primary lung cancer occurs at a very low frequency, accounting for less than 0.05% of all cases. Here, we report the first case of erlotinib-related SPTx in a patient with advanced lung adenocarcinoma in Korea. After 3 cycles of cisplatin-based chemotherapy as first-line therapy, erlotinib was administered as second-line treatment. Asymptomatic SPTx accompanied by a significant decrease in tumor size was observed in the left lung 7 weeks later. The patient received continuous administration of erlotinib, without additional treatment. This case showed that SPTx can occur in patients with primary lung cancer receiving erlotinib, and asymptomatic chemotherapy-related SPTx in primary lung cancer may not require therapeutic intervention.

영주향토음식 콘텐츠개발을 위한 주성분분석 및 문화유산 (소수서원, 부석사) 자원의 활용 연구 (Utilization Research of Cultural Heritage Resources (Sosuseowon & Buseoksa) and Primary Components Analysis for Development of Yeongju Local Food Content)

  • 최은영;안희정
    • 한국식품영양학회지
    • /
    • 제30권5호
    • /
    • pp.1068-1079
    • /
    • 2017
  • This study was applied to the PCA (Primary Components Analysis) for the sixteen table setting at the 2017 Yeongju local food contest. In this contest, we have developed a seonbibansang and a temple one-dish meal. As a result of the correlation analysis, the applicability and composition were 0.7980, harmony and taste were 0.7747 and easiness and composition were 0.7435. In the Primary Component $Y_1$, all the variables $X_1{\cdots}X_{10}$ mean that the quality of the food had positive values greater than zero. The second Primary Component $Y_2$ has a large positive value while $X_4$, $X_5$, $X_6$, $X_7$, $X_9$ have negative values. $Y_2$ is a value representing the sanitation variable, and can be considered a traditional and characteristic table setting natural to the native food in Yeongju. In addition, we developed an-hyangbansang and seonmyoaecheong food content by applying PCA factors (the elements of harmony, ease and sanitation). Table setting of an-hyangbansang provided energy 61.5%, protein 20.0% and fat 18.5% and seonmyoaecheong provided energy 62.7%, protein 15.4% and fat 22.2%. This satisfied the necessary amount of caloric nutrient intake that could be provided in a meal. Especially through story-telling, a modern interpretation - or rebranding - of local and traditional foods could make these traditional food products familiar to consumers currently. The developed table setting is felt to be conductive to the possible commercialization and introduction of traditional food into the mainstream commercial food service industry.