• Title/Summary/Keyword: SecM

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Reproducibility of Regional Pulse Wave Velocity in Healthy Subjects

  • Im Jae-Joong;Lee, Nak-Bum;Rhee Moo-Yong;Na Sang-Hun;Kim, Young-Kwon;Lee, Myoung-Mook;Cockcroft John R.
    • International Journal of Vascular Biomedical Engineering
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    • v.4 no.2
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    • pp.19-24
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    • 2006
  • Background: Pulse wave velocity (PWV), which is inversely related to the distensibility of an arterial wall, offers a simple and potentially useful approach for an evaluation of cardiovascular diseases. In spite of the clinical importance and widespread use of PWV, there exist no standard either for pulse sensors or for system requirements for accurate pulse wave measurement. Objective of this study was to assess the reproducibility of PWV values using a newly developed PWV measurement system in healthy subjects prior to a large-scale clinical study. Methods: System used for the study was the PP-1000 (Hanbyul Meditech Co., Korea), which provides regional PWV values based on the measurements of electrocardiography (ECG), phonocardiography (PCG), and pulse waves from four different sites of arteries (carotid, femoral, radial, and dorsalis pedis) simultaneously. Seventeen healthy male subjects with a mean age of 33 years (ranges 22 to 52 years) without any cardiovascular disease were participated for the experiment. Two observers (observer A and B) performed two consecutive measurements from the same subject in a random order. For an evaluation of system reproducibility, two analyses (within-observer and between-observer) were performed, and expressed in terms of mean difference ${\pm}2SD$, as described by Bland and Altman plots. Results: Mean and SD of PWVs for aorta, arm, and leg were $7.07{\pm}1.48m/sec,\;8.43{\pm}1.14m/sec,\;and\;8.09{\pm}0.98m/sec$ measured from observer A and $6.76{\pm}1.00m/sec,\;7.97{\pm}0.80m/sec,\;and\;\7.97{\pm}0.72m/sec$ from observer B, respectively. Between-observer differences ($mean{\pm}2SD$) for aorta, arm, and leg were $0.14{\pm\}0.62m/sec,\;0.18{\pm\}0.84m/sec,\;and\;0.07{\pm}0.86m/sec$, and the correlation coefficients were high especially 0.93 for aortic PWV. Within-observer differences ($mean{\pm}2SD$) for aorta, arm, and leg were $0.01{\pm}0.26m/sec,\;0.02{\pm}0.26m/sec,\;and\;0.08{\pm}0.32m/sec$ from observer A and $0.01{\pm}0.24m/sec,\;0.04{\pm}0.28m/sec,\;and\;0.01{\pm}0.20m/sec$ from observer B, respectively. All the measurements showed significantly high correlation coefficients ranges from 0.94 to 0.99. Conclusion: PWV measurement system used for the study offers comfortable and simple operation and provides accurate analysis results with high reproducibility. Since the reproducibility of the measurement is critical for the diagnosis in clinical use, it is necessary to provide an accurate algorithm for the detection of additional features such as flow wave, reflection wave, and dicrotic notch from a pulse waveform. This study will be extended for the comparison of PWV values from patients with various vascular risks for clinical application. Data acquired from the study could be used for the determination of the appropriate sample size for further studies relating various types of arteriosclerosis-related vascular disease.

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Flame Propagation in Dust Cloud and its Flammability Limits (더스트 클라우드 내에서의 화염 진행과 연소 한계)

  • Moon, I.;Yoon, Y.;Kim, M.;Cho, T.
    • 한국연소학회:학술대회논문집
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    • 2003.12a
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    • pp.201-208
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    • 2003
  • Wheat dust cloud를 $5{\times}5{\times}214.1cm^3$ square tube내부에 발생시켜 화염의 전달과 연소 한계에 관한 연구를 수행하였다. 사용된 미립자는 $160{\mu}m-300{\mu}m$의 크기로 분류되어 주로 사용되었고 $300{\mu}m-325{\mu}m$크기의 미립자가 더불어 사용되었다. 연소 튜브는 연료로 사용되는 미립자를 튜브의 상단에서부터 컨베이어 벨트를 사용해서 공급받아 튜브의 하단에서 전기코일을 사용하여 점화시키는 구조로 고안되었다. 화염의 최대 진행속도는 작은 크기와 보다 큰 크기의 미립자를 사용했을 때가 각각 523cm/sec와 373cm/sec로 측정되었다. 연소 속도는 입자의 크기와 집접도(concentration)에 따라 변화를 보였는데 최소 3cm/sec에서 최대 7.5cm/sec로 관측되었다. 그러나 화염의 두께는 놀랍게도 입자의 집접도와 큰 연관이 없어 보였는데, 이는 앞으로도 보다 많은 연구를 통한 검증이 필요하리라 생각된다. 끝으로 fuel rich flammability는 $790g/m^3$으로 stoichiometric mixture $230g/m^3$에 비교해 월등히 높은 값으로 관측되었다.

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Two Dimensional Shear Wave Velocity Using the Inversion of Surface Waves (표면파 역산을 이용한 2차원 S파 속도구조에 관한 연구)

  • Jung, Hee-Ok
    • Journal of the Korean earth science society
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    • v.21 no.6
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    • pp.675-682
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    • 2000
  • 25 seismic shot gathers were obtained to study the two dimensional subsurface shear wave velocities in a landfilled area near the Keum river estuary. Borehole(BH#1 and BH#2) tests at two sites were made in the same area. Standard Penetration Tests were also performed at the same time. The 2-D shear wave velocity structure resulted from the inversion of the seismic data shows that the subsurface of the studied area consists of the upper 1${\sim}$3 meter thick layer(200 m/sec${\sim}$700 m/sec), the middle 5${\sim}$8 m thick low velocity layer(100 m/sec${\sim}$400 m/sec), and the lower layer of 1000m/sec or higher shear wave velocities. The thickness of the low velocity layer decreases from the BH #1 site to the BH #2 site. The depth to the basement also decreases toward the BH #2 site. The examination of the S wave velocity structure, the description of the geologic contents, and the Standard Penetration Test values indicate that the middle layer of low shear wave velocity may be related to the clay content of the layer. On the other hand, the Standard Penetration test values increase with depth, showing no significant relationship with the geologic contents of the subsurface. This study shows that the inversion of surface waves can be effective in the study of the shear wave velocity, especially in the area where low velocity layers can be found. The method of inversion of surface waves also can be used as a viable technique to overcome the limit of the seismic refraction method.

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Analyses of Hydrology and Groundwater Level Fluctuation in Granite Aquifer with Tunnel Excavation (터널 굴착에 의한 화강암 대수층의 수리 수문 및 지하수위변동 분석)

  • Chung, Sang-Yong;Kim, Byung-Woo;Kang, Dong-Hwan;Shim, Byoung-Ohan;Cheong, Sang-Won
    • The Journal of Engineering Geology
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    • v.17 no.4
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    • pp.643-653
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    • 2007
  • Average hydraulic conductivity was $2.64{\times}10^{-8}m/sec$ average RQD was 78%, average porosity was 0.51%, and range of groundwater level was $77.06{\sim}125.97m$ by measured in 8 boreholes at the Surak Mt. tunnel area. Groundwater level of two peaks in the Surak Mt. tunnel area were estimated through linear regression analysis for groundwater level versus elevation. And, average horizontal hydraulic gradient in the Surak Mt. tunnel area was calculated 0.267. Minimum, maximum, and average hydraulic conductivities that estimated by field tests were $5.56{\times}10^{-9}m/sec,\;6.12{\times}10^{-8}m/sec,\;and\;2.64{\times}10^{-8}m/sec$, respectively. Groundwater discharge rates per 1 meter that estimated using minimum, maximum, and average hydraulic conductivities and average horizontal hydraulic gradient were $0.00585m^2/day,\;0.06434m^2/day,\;and\;0.02775m^2/day$, respectively. Pure groundwater recharge rate per unit recharge area was calculated 223.96 mm/yr through water balance analysis. Prediction simulation of groundwater level fluctuation with minimum, maximum, and average hydraulic conductivities were conducted. Discharge rate into the Surak Mt. tunnel for minimum hydraulic conductivity was small, but groundwaer drawdown was highly. Discharge rate into the Surak Mt. tunnel for maximum hydraulic conductivity was higher, but groundwaer level was recovered quickly.

Effect of Light Conditions on Photoinhibition of Ginseng and Tobacco (광조건이 인삼과 잎담배의 광저해에 미치는 영향)

  • ;Il Hou
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.30 no.2
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    • pp.126-130
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    • 1985
  • Photoinhibition studies were conducted with ginseng (Panax ginseng) grown under shade and tobacco (N. tobaccum cv. Bulgaria) grown under full sunlight. The plants were exposed to light intensity of 580, 1280, 1770, 2580 ${\mu}$E/㎡/sec in normal air for 3.6 9 hours. Light saturation of ginseng was observed at 550 ${\mu}$E/㎡/sec and that of tobacco was at 1600 ${\mu}$E/㎡/sec. Tobacco exposed to high light intensity and long duration of light irradiation didn't show entire reduction in photosynthetic capacity. But in ginseng, 20.3% of photosynthesis was reduced in light intensity of 2,580 ${\mu}$E/㎡/sec during 9 hours. Light response in photosynthesis differed considerably between tobacco and ginseng, and ginseng exposed to high light intensity showed remarkable reduction in photosynthesis. The extent of photoinhibition of ginseng was dependent on the length of exposure to the high light intensity. Stomatal resistance of ginseng seemed not to be changed by photoinhibition but mesophyll resistance was increased.

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Estimating the shear velocity profile of Quaternary silts using microtremor array (SPAC) measurements (Microtremor 배열 (SPAC) 측정을 이용한 제4기 실트층의 S파 속도구조 추정)

  • Roberts James;Asten Michael
    • Geophysics and Geophysical Exploration
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    • v.8 no.1
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    • pp.34-40
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    • 2005
  • We have used the microtremor method, with arrays of up to 96 m diameter, to carry out non-invasive estimation of shear-wave velocity profiles to a depth of 30 to 50 m in unconsolidated Quaternary Yarra Delta sediments. Two silt units (Coode Island Silt, and Fishermans Bend Silt) dominate our interpretation; the method yields shear velocities for these units with precision of $5\%$, and differentiates between the former, softer unit ($V_s$=130 m/sec) and the latter, firmer unit ($V_s$=235 m/sec). Below these silts, the method resolves a firm unit correlating with known gravels ($V_s$ 500 to 650 m/sec). Using surface traverses with the single-station H/V spectral ratio method, we show that the variation in thickness of the softer silt can be mapped rapidly but only qualitatively. The complexity of the geological section requires that array methods be used when quantitative shear-wave velocity profiles are desired.

Analysis of Seawater Transport based on Field Measurements at Pier-bridge between Busan New-port and the Nakdong River Estuary (부산 신항-낙동강 하구역 연결잔교부의 물질수송 해석(I) - 현장조사를 통한 잔교부 해수소통량 평가 -)

  • Lee, Young-Bok;Tawaret, Attapon;Kim, Heon-Tae;Yoon, Han-Sam
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.14 no.3
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    • pp.189-195
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    • 2008
  • This study analyzed the characteristics of sea water transport between Busan New-port and the Nakdong River estuary. A current meter was placed on a pier bridge and the current velocity was analyzed to determine the flow direction. Water temperature, salinity, turbidity, and tide were also measured to determine the characteristics of sea water and to describe the tidal current between the two regions. The results indicated that the dominant outflow direction of the ebb tidal current was from the Nakdong River estuary to Busan New-port. Conversely, during a flood tide, the dominant direction was from Busan New-port to the Nakdong River estuary. The maximum current speed during the first and second field measurements was about 13.18 and 30.80 cm/ sec, respectively. During the first field measurement, the total volume of sea water transport was $184.71\;m^3/sec$ and the residual volume transport was $+59.74\;m^3/sec$. By contrast, during the second field measurement, the respective values were $331.15\;m^3/sec$ and $28.88\;m^3/sec$.

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Kinetics of Drying Shiitake Mushroom, Lentinus edodes sanryun No. 1 (표고버섯의 열풍건조속도론(熱風乾燥速度論)에 관한 연구(硏究))

  • Cho, Duk-Bong;Kim, Dong-Pil;Choi, Choon-Soon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.10 no.1
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    • pp.53-60
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    • 1981
  • Dehydration phenomena has been studied for the shiitake mushroom Lentinus edodes sanryun No.1, through which examine the effect of temperature and air velocity and derivation of its kinetics. Temperature effect for the dehydration rate constant were examined under the constant air velocity (1.5m/sec) with the variation of temperature from $40^{\circ}C$ to $55^{\circ}C$. Water content were reduced exponentially with the course of time and calculated dehydration rate constant values varies with temperature with an Arrhenius-type relationship, which had been expected in the chemical reaction kinetics. Influence of air velocity for the dehydration rate constant under the constant temperature $(45^{\circ}C)$ showed interesting results. For the range 1.0m/sec to 2.0m/sec, dehydration rate constant values are increased with the air velocity, but for the 2.0 to 3.1m/sec, dehydration rate constant values are decreased which were caused by case hardening. One of the selected conditions in the optimal dehydration range, temperature $50^{\circ}C$, air velocity 2m/see, and its measured humidity 38-41%, mathematical model of dehydration curve and dehydration rate equations were developed and the resulting kinetic models were X=6.94 $e^{-0.345t}$ and dx/dt = -2.39 $e^{-0.345t}$

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Studies on the Overflow from Torrential Stream -A Case Study at the Samsung-cheon in Mt. Kwanak- (야계(野溪)의 월류발생(越流發生)에 관(關)한 연구(硏究) -관악산(冠岳山) 삼성천(三聖川)에서의 시험사례(試驗事例)-)

  • Woo, Bo Myeong;Kim, Kyong Ha;Jeong, Do Hyeon
    • Journal of Korean Society of Forest Science
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    • v.77 no.3
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    • pp.269-275
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    • 1988
  • To investigate the cause of overflow in the torrential stream, the estimated peak flow of run-off and the maximum tarring capacity of the stream were measured at the upstream of Samsung-cheon located in Kwanak Aboretum during July, 1987. The results obtained from this study could be summarized as follows : 1. The surveyed catchment area was 477ha, which was 116 of the designed area (410ha) by the plan. 2. The maximum rainfall intensity measured was 99.5mm/hr and was almost same as the designed intensity(100mm/hr). 3. The surveyed run-off coefficient was 0.672 that was about twice as much as designed one(0.35). 4. The surveyed peak flow of run-off was $88.59m^3/sec$, 222% as large the designed one($39.9m^3/sec$). 5. The designed cross-sectional area of the stream was $17.25m^2$, which was 68% of the designed one$25.43m^2$. 6. The surveyed hydraulic mean radius was 0.94m, which was shorter than the designed one(1.28m). 7. The surveyed mean stream-bed gradient(0.998%) was almost the same as the designed one(1.00%). 8 The surveyed maximum velocity of flow passing through the stream was 2.87m/sec, 78.0 of the designed one(3.68m/sec). 9 The surveyed run-off capacity of the stream was $49.51m^3/sec$, 53% of the designed one ($93.5m^3/sec$).

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Molecular cloning and sequence Analysis of the Gene for SecY from Streptomyces coelicolor (Muller) (Streptomyces coelicolor에서 secY 유전자의 클로닝과 염기서열 결정)

  • Kim, Sang-Suk;Hyun, Chang-Gu;Kim, Young-Min;Lee, Joo-Hun;Chung, In-Kwon;Kim, Dae-Myung;Suh, Joo-Won
    • Microbiology and Biotechnology Letters
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    • v.23 no.6
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    • pp.678-686
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    • 1995
  • SecY is a central component of the protein export machinery that mediate the translocation of secretory proteins across the plasma membrane of Escherichia coli. In order to study the mechanism of protein secretion in Streptomyces, we have done cloning and sequencing of the Streptomyces coelicolor secY gene by using polymerase chain reaction method. The nucleotide sequence of the gene for SecY from S. coelicolor showed over 58% identity to that of M. luteus. The deduced amino acid sequences were highly homologous to those of other known SecY polypeptides, all having the potential to form 10 transmembrane segments, and especially second, fifth, and tenth segments were particularly conserved, sharing greater than 75% identity with W. lute s SecY. We propose that the conserved membrane-spanning segments actively participate in protein export. In B. subtilis and E. coli, the secY gene is a part of the spc operon, is preceded by the gene coding for ribosomal protein L15, and is likety coupled transcriptionally and translationally to the upstream L15 gene. In the other hand, secY gene of S. coelicolor and M. luteus have its own promoter region, are coupled translationally with adk gene and pr sented in adk operon.

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